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41. 发明申请

US20070140604A1 Bearing unit and rotary drive using the same 审中-公开
标题翻译：轴承单元和旋转驱动使用相同
公开(公告)号：US20070140604A1
公开(公告)日：2007-06-21
申请号：US11604721
申请日：2006-11-28
申请人： Yuji Shishido , Kenichiro Yazawa , Takeshi Kaneko , Kiyoyuki Takada , Hiroshi Sato , Yoshiaki Kakinuma , Ichiro Nakamura
发明人： Yuji Shishido , Kenichiro Yazawa , Takeshi Kaneko , Kiyoyuki Takada , Hiroshi Sato , Yoshiaki Kakinuma , Ichiro Nakamura
IPC分类号： F16C32/06
CPC分类号： F16C33/107 , F16C17/026 , F16C17/107 , F16C33/103 , H02K5/1675 , H02K7/085
摘要： A bearing unit for rotatably supporting a shaft comprises a seamless holding member with a gap allowing a shaft to run through and extend to the outside, a bearing arranged in the inside of the holding member to rotatably support the shaft so as to make it radially revolvable, an anti-shaft-release member fitted to the shaft so as to abut the bearing in order to prevent the shaft from slipping away in the thrusting direction and a space-forming member arranged in the inside of the holding member so as to secure a space around the anti-shaft-release member. A bearing unit may further comprise an lubricating oil seal member and the space-forming member may be used to form a passage way for lubricating oil to prevent lubricating oil from leaking.
摘要翻译：用于可旋转地支撑轴的轴承单元包括具有允许轴穿过并延伸到外部的间隙的无缝保持构件，布置在保持构件内侧的轴承，以可旋转地支撑轴，以使其可径向旋转安装在所述轴上以抵抗所述轴承以防止所述轴在推动方向上滑落的防轴释放构件以及布置在所述保持构件内部的空间形成构件，以便确保防轴释放构件周围的空间。轴承单元还可以包括润滑油密封构件，并且空间形成构件可以用于形成用于润滑油的通道，以防止润滑油泄漏。

42. 发明申请

US20060270682A1 Substituted Aryloxymethyl Bicyclicmethyl Acetamide Compounds 失效
公开(公告)号：US20060270682A1
公开(公告)日：2006-11-30
申请号：US11421242
申请日：2006-05-31
申请人： Tadashi Inoue , Satoshi Nagayama , Yuji Shishido
发明人： Tadashi Inoue , Satoshi Nagayama , Yuji Shishido
IPC分类号： A61K31/501 , A61K31/4439 , A61K31/428 , A61K31/423 , A61K31/4184 , A61K31/4192
CPC分类号： C07D277/62 , C07D209/34 , C07D231/56 , C07D235/06 , C07D235/26 , C07D249/18 , C07D263/58
摘要： This invention provides a compound of the formula (I): wherein A=B=D represents NR10—C(O)—NR9, S—C(O)—NR9, NR9—C(O)—S, NR9—C(O)—O, CR10—C(O)—NR9, O—C(O)—NR9, NR10—C(O)—CR9, NR10—NR9—C(O), C(O)—NR9—NR10, NR10—N═CR9, N═N—CR9, NR10—CR9═N, N═CR9—NR10, NR10—N═N, N═N—NR10, S—CR9═N or N═CR9—S; X1 represents CR1 or N; X2 and X3 each independently represents CR8 or N; R1, R6, R8, R9 and R10 each independently represents hydrogen, halogen, hydroxy, (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkoxy, (C1-C6)alkoxy-(C1-C6)alkyl, (C1-C6)alkoxy-(C1-C6)alkoxy, halo(C1-C6)alkyl, (C1-C6)alkylthio, (C1-C6)alkylsulfinyl or (C1-C6)alkylsulfonyl; R2, R3, R4, and R5 each independently represents hydrogen, (C1-C6)alkyl, halogen, halo(C1-C6)alkyl, or hydroxy(C1-C6)alkyl; and R7 represents halogen, (C1-C6)alkyl, halo(C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkoxy, (C1-C6)alkoxy-(C1-C6)alkyl, (C1-C6)alkoxy-(C1-C6)alkoxy, [(C1-C6)alkyl]NH— or [(C1-C6)alkyl]2N—; or a pharmaceutically acceptable salt thereof, provided that: (i) when A=B=D represents NR10—N═N or N═N—NR10, then R2 represents (C1-C6)alkyl, halogen, halo(C1-C6)alkyl or hydroxy(C1-C6)alkyl; or (ii) when A=B=D represents NR10—N═N or N═N—NR10, and R2 represents (C1-C6)alkyl, then R7 represents halogen, (C1-C6)alkyl, (C1-C6)alkoxy, hydroxy(C1-C6)alkoxy, (C1-C6)alkoxy-(C1-C6)alkyl, (C1-C6)alkoxy-(C1-C6)alkoxy, [(C1-C6)alkyl]NH— or [(C1-C6)alkyl]2N—. These compounds are useful for the treatment of disease conditions caused by overactivation of VR1 receptor such of pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.

43. 发明申请

US20050254736A1 Bearing unit, and motor using same 失效
公开(公告)号：US20050254736A1
公开(公告)日：2005-11-17
申请号：US11185832
申请日：2005-07-21
申请人： Yuji Shishido , Kenichiro Yazawa , Shinichiro Kato , Shuichi Kikuchi , Toru Ujiie
发明人： Yuji Shishido , Kenichiro Yazawa , Shinichiro Kato , Shuichi Kikuchi , Toru Ujiie
IPC分类号： F16C17/02 , F16C17/04 , F16C17/10 , F16C17/26 , F16C29/06 , F16C32/06 , F16C33/10 , F16C33/20 , F16C35/02 , G11B19/20 , H02K5/16 , H02K7/08
CPC分类号： F16C35/02 , F16C17/026 , F16C17/107 , F16C33/103 , F16C33/107 , F16C41/008 , F16C2370/12 , G11B19/2018 , H02K5/1677 , H02K7/085
摘要： A bearing unit is provided which includes a shaft (51) to support rotatably, radial bearing (55) to support the shaft (51) circumferentially, a thrust bearing (66) to support the shaft (51) in the direction of thrusting, and a housing (56) having the radial bearing (55) and thrust bearing (66) disposed therein and in which a viscous fluid (57) is filled. The housing (56) has a sealed structure except for a shaft insertion hole (65) formed therein and through which the shaft 51 is introduced. Between the outer surface of the shaft (51) and the inner surface of the shaft insertion hole (65), there is defined a gap (69) having a sufficient width to prevent the viscous fluid (57) filled in the housing (56) from leaking out of the latter. The housing (56) is formed as a one-piece structure by molding a synthetic resin.

44. 发明申请

US20050163404A1 Bearing unit and rotation drive device using the same 失效
标题翻译：轴承单元和旋转驱动装置使用相同
公开(公告)号：US20050163404A1
公开(公告)日：2005-07-28
申请号：US10506433
申请日：2004-01-08
申请人： Yuji Shishido , Kenichiro Yazawa , Takeshi Kaneko , Kiyoyuki Takada , Hiroshi Sato , Yoshiaki Kakinuma , Ichiro Nakamura
发明人： Yuji Shishido , Kenichiro Yazawa , Takeshi Kaneko , Kiyoyuki Takada , Hiroshi Sato , Yoshiaki Kakinuma , Ichiro Nakamura
IPC分类号： F16C17/10 , F16C33/10 , H02K5/16 , H02K5/167 , H02K7/08 , F16C32/06
CPC分类号： F16C33/107 , F16C17/026 , F16C17/107 , F16C33/103 , H02K5/1675 , H02K7/085
摘要： A bearing unit (90) for rotatably supporting a shaft (100) comprises a seamless holding member (120) with a gap allowing a shaft to run through and extend to the outside, a bearing (130) arranged in the inside of the holding member to rotatably support the shaft so as to make it radially revolvable, an anti-shaft-release member (115) fitted to the shaft so as to abut the bearing in order to prevent the shaft from slipping away in the thrusting direction and a space-forming member (113) arranged in the inside of the holding member so as to secure a space around the anti-shaft-release member. A bearing unit may further comprise an lubricating oil seal member and the space-forming member may be used to form a passage way for lubricating oil to prevent lubricating oil from leaking.
摘要翻译：用于可旋转地支撑轴（100）的轴承单元（90）包括具有允许轴穿过并延伸到外部的间隙的无缝保持构件（120），布置在保持构件内部的轴承（130）为了可旋转地支撑轴以使其可径向旋转，安装在轴上的防轴释放构件（115）以便抵靠轴承，以防止轴在推动方向上滑落，形成构件（113），其设置在所述保持构件的内部，以便确保所述防轴释放构件周围的空间。轴承单元还可以包括润滑油密封构件，并且空间形成构件可以用于形成用于润滑油的通道，以防止润滑油泄漏。

45. 发明授权

US06772427B2 Motor securing structures and disc drive 失效
标题翻译：电机固定结构和磁盘驱动器
公开(公告)号：US06772427B2
公开(公告)日：2004-08-03
申请号：US10182050
申请日：2002-10-24
申请人： Yuji Shishido , Takashi Mochida , Mitsuhiro Ueno , Kazutaka Nakajima
发明人： Yuji Shishido , Takashi Mochida , Mitsuhiro Ueno , Kazutaka Nakajima
IPC分类号： G11B2300
CPC分类号： G11B19/2009 , H02K5/26
摘要： A structure for securing a spindle motor (15) supported on a motor substrate (32) to a chassis (13). The motor substrate (32) and the chassis (13) are coupled by at least three coupling sections (33). At least two of the coupling sections (33) are fixed support members (33a) which hold and space the motor substrate (32) and the chassis (13) from each other at a prescribed distance. The remaining coupling section is an adjusting support member (33b) that holds the motor substrate (32) and the chassis (13) from each other at a variable distance. Rigid holding means is incorporated in the adjusting support member (33b) and holds the motor substrate (32) and the chassis (13) so that the motor substrate (32) and the chassis (13) remain rigid.
摘要翻译：一种用于将支撑在马达基板（32）上的主轴马达（15）固定到底盘（13）上的结构。马达基板（32）和底架（13）通过至少三个连接部分（33）联接。耦合部分（33）中的至少两个是固定的支撑部件（33a），其将电动机基板（32）和底架（13）保持并以规定距离彼此间隔开。剩余的联接部分是以可变距离彼此保持马达基板（32）和底架（13）的调节支撑部件（33b）。刚性保持装置结合在调节支撑构件（33b）中并且保持马达基板（32）和底架（13），使得马达基板（32）和底架（13）保持刚性。

46. 发明授权

US06506775B1 Substituted benzylaminopiperidine compounds 失效
标题翻译：取代的苄基氨基哌啶化合物
公开(公告)号：US06506775B1
公开(公告)日：2003-01-14
申请号：US09564398
申请日：2000-05-01
申请人： Kunio Satake , Yuji Shishido , Hiroaki Wakabayashi
发明人： Kunio Satake , Yuji Shishido , Hiroaki Wakabayashi
IPC分类号： C07D21156
CPC分类号： C07D211/56
摘要： The invention provides a compound of formula (I): and its pharmaceutically acceptable salts, wherein R is halo C2-C8 alkenyl or halo C2-C8 alkynyl; R1 is hydrogen, halo or C1-C6 alkoxy; or R and R1, together with the two carbon atoms to which they are attached, form a C4-C6 cycloalkyl or a C4-C6 oxacycloalkyl ring wherein said ring may be optionally substituted by one or more substituents selected from the group consisting of halo, C1-C6 alkyl and halo C1-C6 alkyl; X is C1-C6 alkoxy, halo C1-C6 alkoxy, phenoxy or halo; and Ar is phenyl optionally substituted by halo. These compounds are useful in the treatment of a gastrointestinal disorder; a central nervous system (CNS) disorder; an inflammatory disease; emesis; urinary incontinence; pain; migraine; sunburn; diseases, disorders and adverse conditions caused by Heliobacter pylori; or angiogenesis especially CNS disorders in a mammalian subject, especially humans.
摘要翻译：本发明提供式（I）化合物及其药学上可接受的盐，其中R为卤代C 2 -C 8烯基或卤代C 2 -C 8炔基; R 1为氢，卤素或C 1 -C 6烷氧基;或R和R 1与它们连接的两个碳原子形成C 4 -C 6环烷基或C 4 -C 6氧杂环烷基环，其中所述环可任选地被一个或多个选自卤素，C 1 -C 6烷基和卤代C 1 -C 6烷基的取代基取代， C6烷基; X是C1-C6烷氧基，卤代C1-C6烷氧基，苯氧基或卤代; 并且Ar是任选被卤素取代的苯基。这些化合物可用于治疗胃肠道疾病; 中枢神经系统（CNS）障碍; 炎性疾病; 呕吐尿失禁疼痛; 偏头痛晒斑; 由幽门螺杆菌引起的疾病，病症和不良状况; 或血管发生，尤其是哺乳动物受试者尤其是人类的CNS疾病。

47. 发明授权

US6005749A Rotation drive apparatus 失效
标题翻译：旋转驱动装置
公开(公告)号：US6005749A
公开(公告)日：1999-12-21
申请号：US35845
申请日：1998-03-06
申请人： Hiroshi Ikuta , Fumiharu Sudo , Toru Nakahara , Mitsuhiro Ueno , Yuji Shishido
发明人： Hiroshi Ikuta , Fumiharu Sudo , Toru Nakahara , Mitsuhiro Ueno , Yuji Shishido
IPC分类号： F16F15/36 , G01M1/36 , G11B25/04 , G11B33/08 , H02K15/16 , G11B17/02 , H02K5/24
CPC分类号： G01M1/36 , F16F15/363 , G11B25/043 , G11B33/08 , H02K15/165
摘要： A magnet is provided which holds spherical balancers in the central portion of a rotor when the rotation of the rotor is stopped. When rotations of the rotor is started, a larger torque T.sub.0 is transmitted from the rotor to the balancers. Thus, the balancers quickly start rotating. When the rotor rotates at high speed, the centrifugal force separates the balancers from the magnet and moves the same to the outer wall portion of the rotor. At this time, a torque T.sub.0 which is transmitted from the rotor to the balancer is reduced so that the balancers are moved in the circumferential direction. Thus, the automatic aligning operation is performed. The number (n) of the balancers is made to be a value obtained by the following equation:n=180/.theta.+0.5 (all digits to the right of the decimal point are discarded)wherein .theta.: angle of balancer balls disposed in the outer portion, in which .theta.=2sin.sup.-1 {r/(R-r)}R: radius of movable spacer: radius of each balancer ball
摘要翻译：提供一种磁体，当转子的旋转停止时，磁体在转子的中心部分保持球形平衡器。当转子的转动开始时，转矩越大，转矩越大，平衡器转速越大。因此，平衡机迅速开始旋转。当转子高速旋转时，离心力将平衡器与磁体分开并将其移动到转子的外壁部分。此时，从转子传递到平衡器的转矩T0减小，使得平衡器沿圆周方向移动。因此，执行自动对准操作。平衡器的数量（n）为通过以下等式获得的值：n = 180 /θ+0.5（舍弃小数点右侧的所有数字）其中theta：平衡器球的角度位于外部，其中θ= 2sin-1 {r /（Rr）} R：可移动空间的半径r：每个平衡球的半径

48. 发明授权

US08252790B2 Pyrazole-3-carboxamide derivative having 5-HT2B receptor antagonist activity 有权
标题翻译：具有5-HT2B受体拮抗剂活性的吡唑-3-甲酰胺衍生物
公开(公告)号：US08252790B2
公开(公告)日：2012-08-28
申请号：US13129916
申请日：2009-11-24
申请人： Tatsuya Yamagishi , Kiyoshi Kawamura , Tadashi Inoue , Yuji Shishido , Hiroaki Ito
发明人： Tatsuya Yamagishi , Kiyoshi Kawamura , Tadashi Inoue , Yuji Shishido , Hiroaki Ito
IPC分类号： A61K31/5375 , C07D413/02
CPC分类号： C07D487/04 , A61K31/415 , A61K31/4155 , A61K31/437 , A61K31/454 , A61K31/5377 , A61K31/553 , C07D231/14 , C07D401/04 , C07D401/14 , C07D403/04 , C07D409/04 , C07D413/14 , C07D417/04 , C07D471/04
摘要： Disclosed is a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof, which is useful as a selective antagonist of a 5-HT2B receptor. The compound and salt are useful for treatment or prevention of various diseases and conditions associated with a 5-HT2B receptor.
摘要翻译：公开了通式（I）表示的化合物或其药学上可接受的盐，其可用作5-HT 2B受体的选择性拮抗剂。该化合物和盐可用于治疗或预防与5-HT 2B受体相关的各种疾病和病症。

49. 发明授权

US08153651B2 Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same 失效
标题翻译：酰胺衍生物作为离子通道配体和药物组合物及其使用方法
公开(公告)号：US08153651B2
公开(公告)日：2012-04-10
申请号：US12742425
申请日：2008-11-13
申请人： Matthew Cox , Donogh John Roger O'Mahony , Maria De Los Angeles Estiarte-Martinez , Tadashi Kawashima , Satoshi Nagayama , Yuji Shishido , Hirotaka Tanaka , Matthew Alexander James Duncton , Andrew Antony Calabrese
发明人： Matthew Cox , Donogh John Roger O'Mahony , Maria De Los Angeles Estiarte-Martinez , Tadashi Kawashima , Satoshi Nagayama , Yuji Shishido , Hirotaka Tanaka , Matthew Alexander James Duncton , Andrew Antony Calabrese
IPC分类号： A01N43/42 , A61K31/44 , C07D471/02
CPC分类号： C07D215/48 , C07C311/08 , C07C2602/10 , C07D265/36 , C07D311/58 , C07D311/66 , C07D319/20 , C07D405/04
摘要： Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
摘要翻译：公开了具有下列化学式的化合物：化合物可以制备成药物组合物，并且可以用于预防和治疗哺乳动物包括人的多种病症，包括作为非限制性实例的疼痛，炎症，创伤性损伤等。

50. 发明授权

US07753590B2 Bearing unit and driving motor using the bearing unit 失效
标题翻译：轴承单元和驱动电机使用轴承单元
公开(公告)号：US07753590B2
公开(公告)日：2010-07-13
申请号：US11758312
申请日：2007-06-05
申请人： Yuji Shishido , Kenichiro Yazawa , Makoto Chiyoda
发明人： Yuji Shishido , Kenichiro Yazawa , Makoto Chiyoda
IPC分类号： F16C32/06
CPC分类号： F16C33/74 , F16C2370/12
摘要： A bearing unit includes: a radial bearing for bearing in a circumferential direction of a shaft; a thrust bearing for bearing one end in a thrust direction of the shaft; a housing provided on the outside of the radial bearing and the thrust bearing and filled with a viscous fluid; a seal member united with the housing so as to contain the radial bearing and the thrust bearing in a sealed state, the seal member having a shaft passing hole through which the shaft is passed; and a passage for discharging air present inside the housing, the passage formed between the housing and the radial bearing, and the passage providing communication between the one end side and the other end side in the thrust direction of the shaft projecting from the radial bearing, wherein the cross-sectional shape of the passage is a shape including at least one acute angle.
摘要翻译：轴承单元包括：用于在轴的圆周方向上轴承的径向轴承; 用于在轴的推力方向上承载一端的止推轴承; 设置在径向轴承的外侧的壳体和止推轴承，并且填充有粘性流体; 密封构件，其与所述壳体结合，以将所述径向轴承和所述推力轴承保持在密封状态，所述密封构件具有轴穿过所述轴通过的轴穿过孔; 以及用于排出存在于壳体内的空气的通道，形成在壳体和径向轴承之间的通道，以及在从径向轴承突出的轴的推力方向上的一端侧和另一端侧之间提供连通的通道，其中所述通道的横截面形状是包括至少一个锐角的形状。

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