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41. 发明授权

US5824014A Medical therapy device producing a variable therapy in response to measured sensor values corrected with temporal fluctuation values 失效
标题翻译：医疗治疗装置响应于用时间波动值校正的测量传感器值产生可变疗法
公开(公告)号：US5824014A
公开(公告)日：1998-10-20
申请号：US806753
申请日：1997-03-03
申请人： Tran Thong , Dennis Digby , Max Schaldach
发明人： Tran Thong , Dennis Digby , Max Schaldach
IPC分类号： A61N1/365 , A61N1/368 , A61N1/39
CPC分类号： A61N1/368 , A61N1/36557 , A61N1/36585 , A61N1/3962
摘要： A medical therapy device includes at least one sensor for detecting a varle that can be measured on the body of a patient. An evaluating and control device is connected to the output of the sensor. A therapy device is connected to the output of the evaluating and control device and provides different therapies or therapy variables as a function of the value of the therapy control variable. A processing unit has an input connected to the output of a time controlled fluctuation-value generator which is connected between the output of the sensor and the input of the evaluating and control device. At least one temporal fluctuation value is combined with the sensor measured value in a processing unit which produces a corrected sensor measured value that is fed to the evaluating and control device so that, a value of the therapy control variable determined by the evaluating and control device is changed in comparison to a determination of the therapy control variable for an original measured value and/or a measured value corrected with a different fluctuation value.
摘要翻译：医疗治疗装置包括至少一个传感器，用于检测可在患者身上测量的变量。评估和控制装置连接到传感器的输出端。治疗装置连接到评估和控制装置的输出，并且作为治疗控制变量的值提供不同的疗法或治疗变量。处理单元具有连接到传感器的输出和评估和控制装置的输入之间的时间控制波动值发生器的输出的输入。至少一个时间波动值与处理单元中的传感器测量值组合，该处理单元产生被馈送到评估和控制装置的校正的传感器测量值，使得由评估和控制装置确定的治疗控制变量的值与用于原始测量值的治疗控制变量的确定和/或用不同波动值校正的测量值相比变化。

42. 发明授权

US5609611A Pacemaker system with porous electrode and residual charge or after-potential reduction 失效
标题翻译：起搏器系统具有多孔电极和残留电荷或后电位降低
公开(公告)号：US5609611A
公开(公告)日：1997-03-11
申请号：US403723
申请日：1995-03-17
申请人： Armin Bolz , Max Schaldach
发明人： Armin Bolz , Max Schaldach
IPC分类号： A61N1/05 , A61N1/37 , A61N1/36
CPC分类号： A61N1/3706 , A61N1/0565
摘要： A cardiac pacemaker system is provided which includes a stimulation electrode adapted for being anchored in the heart. An output capacitor is coupled to the stimulation electrode. A first circuit coupled to the output capacitor generates stimulation pulses. A second circuit coupled to the output capacitor generates an autoshort pulse following each stimulation pulse to reduce a residual charge of the output capacitor for eliminating an after potential following a stimulation pulse by the stimulation electrode. A third circuit coupled to the output capacitor acquires an evoked pulse of the heart from an electrical signal picked up by the stimulation electrode. The stimulation electrode includes a porous surface coating made of an inert material and has an active surface that is substantially larger than a surface of the basic geometric form of the stimulation electrode. The second circuit includes circuit means for changing the time duration of the autoshort pulses as a function of the acquisition of the evoked pulses, with the time duration of the autoshort pulses being limited to 70 ms.
摘要翻译： PCT No.PCT / DE93 / 00887 Sec。 371日期1995年3月17日 102（e）1995年3月17日PCT PCT 1993年9月16日PCT公布。公开号WO94 / 06508 日期1994年3月31日提供了一种心脏起搏器系统，其包括适于锚定在心脏中的刺激电极。输出电容器耦合到刺激电极。耦合到输出电容器的第一电路产生刺激脉冲。耦合到输出电容器的第二电路在每个刺激脉冲之后产生自动转换脉冲，以减少输出电容器的剩余电荷，以消除刺激电极在刺激脉冲之后的后置电位。耦合到输出电容器的第三电路从由刺激电极拾取的电信号获取心脏的诱发脉冲。刺激电极包括由惰性材料制成的多孔表面涂层，并且具有基本上大于刺激电极的基本几何形状的表面的活性表面。第二电路包括电路装置，用于根据获取的诱发脉冲改变自动更新脉冲的持续时间，自动更新脉冲的持续时间被限制为70ms。

43. 发明授权

US5447523A Pacemaker with physiological control of stimulation 失效
标题翻译：起搏器具有刺激的生理控制
公开(公告)号：US5447523A
公开(公告)日：1995-09-05
申请号：US277290
申请日：1994-07-22
申请人： Max Schaldach
发明人： Max Schaldach
IPC分类号： A61N1/365
CPC分类号： A61N1/36514
摘要： A demand cardiac pacemaker implantable in a patient which includes a pulse generator which generates stimulating pulses at a controllable variable rate and has electrodes for applying stimulating pulses from the pulse generator to the heart of a patient. The length of the pre-ejection period (PEP) for the left ventricle in each heart cycle, which length is a function of the physiological demand of the patient, is detected and an output signal which is a function of the length of the pre-ejection period is produced. This output signal is used to control the pulse generator to produce stimulating pulses at a rate based on the output signal, and to apply the stimulating pulses to the electrodes in the absence of spontaneous heart action.
摘要翻译：可植入患者体内的需求心脏起搏器，其包括以可控可变速率产生刺激脉冲的脉冲发生器，并具有用于将来自脉冲发生器的刺激脉冲施加到患者心脏的电极。检测每个心脏周期中左心室的预喷射时期（PEP）的长度，该长度是患者的生理需求的函数，并且输出信号是预处理时间长度的函数，产生喷射期。该输出信号用于控制脉冲发生器以基于输出信号的速率产生刺激脉冲，并且在没有自发心脏作用的情况下将刺激脉冲施加到电极。

44. 发明授权

US5336243A Physiologically controlled pacemaker and pacemaker control system with detection of the spatial position of the patient 失效
标题翻译：生理控制的起搏器和起搏器控制系统，检测患者的空间位置
公开(公告)号：US5336243A
公开(公告)日：1994-08-09
申请号：US31911
申请日：1993-03-16
申请人： Max Schaldach
发明人： Max Schaldach
IPC分类号： A61N1/365
CPC分类号： A61N1/36542 , A61N1/36585
摘要： A cardiac pacemaker control system includes a stress detector system (1) for producing a controlled basic stimulation rate based on signals picked up within a patient's body related to physical stress and derived from a pre-ejection period of the patient. A detection device (10, 15) detects a spatial orientation of the patient, and produces an output switching signal (20) for changing the controlled basic stimulation rate depending upon the position of the patient which represents an additional measure of physical stress.
摘要翻译：心脏起搏器控制系统包括应力检测器系统（1），用于基于在与患者身体相关的患者身体中拾取的信号产生受控的基本刺激速率，并从患者的预喷射期间导出。检测装置（10,15）检测患者的空间取向，并且产生输出切换信号（20），用于根据代表身体应力的附加量度的患者的位置来改变受控的基本刺激速率。

45. 发明授权

US5318592A Cardiac therapy system 失效
标题翻译：心脏治疗系统
公开(公告)号：US5318592A
公开(公告)日：1994-06-07
申请号：US943249
申请日：1992-09-14
申请人： Max Schaldach
发明人： Max Schaldach
IPC分类号： A61N1/365 , A61N1/36
CPC分类号： A61N1/365
摘要： A cardiac therapy system for use with a conventional cardiac pacemaker ciit is controlled by activity signals of the autonomous nervous system (ANS) in a patient's body which constitute a measure for the patient's cardiovascular output requirement. The system includes pickup circuitry for detecting at least the autonomous nervous system activity signals in the patient's body, a control circuit for generating control signals as a function of time and/or intensity of the autonomous nervous system signals picked up in the patient's body, a neurostimulator for changing vascular resistance by nerve stimulation of the patient in adaptation to the patient's intracardial output requirement, in response to control signals from the control circuit, an arrythmia suppressor for generating anti-arrhythmia stimulation pulses to the patient's heart which are controlled by control signals from the control circuit, and a pump assist for assisting the pumping of the patient's heart in response to control signals from the control circuit.
摘要翻译：与常规心脏起搏器电路一起使用的心脏治疗系统由患者体内的自主神经系统（ANS）的活动信号控制，构成对患者心血管输出要求的度量。该系统包括用于至少检测患者身体中的自主神经系统活动信号的拾取电路，用于产生作为在患者体内拾取的自主神经系统信号的时间和/或强度的函数的控制信号的控制电路，神经刺激器，用于响应于来自控制电路的控制信号，适应于患者的心内输出要求，通过患者的神经刺激来改变血管阻力，用于产生由控制信号控制的患者心脏的抗心律失常刺激脉冲的心律失常抑制器以及响应于来自控制电路的控制信号而辅助泵送患者心脏的泵辅助。

46. 发明授权

US4932408A Cardiac pacemaker 失效
标题翻译：心脏起搏器
公开(公告)号：US4932408A
公开(公告)日：1990-06-12
申请号：US26678
申请日：1987-03-17
申请人： Max Schaldach
发明人： Max Schaldach
IPC分类号： A61N1/365
CPC分类号： A61N1/36585
摘要： A cardiac pacemaker for implanting in a patient includes a device for applying stimulating pulses to the heart of the patient at a rate determined by a pacing parameter; a plurality of devices for detecting a corresponding plurality of physiological parameters which are respectively associated with physical exertion of the patient and producing a corresponding plurality of output signals representative of the corresponding physiological parameters; a circuitry device receiving the first output signals for varying the pacing parameter as a function of the first output signal, an external programming device in communication with the circuitry device; a linking element in communication with the external programming devices which selectably links the circuitry device with a selectable one of the plurality of device for detecting; and the external programming device causing the linking element to select a given one of the plurality of detecting device for linking with the circuitry device.
摘要翻译：用于植入患者的心脏起搏器包括用于以由起搏参数确定的速率将刺激脉冲施加到患者心脏的装置; 多个装置，用于检测分别与患者的身体运动相关联的相应的多个生理参数，并产生表示对应的生理参数的对应的多个输出信号; 接收用于根据第一输出信号改变起搏参数的第一输出信号的电路装置，与电路装置通信的外部编程装置; 与外部编程设备通信的链接元件，其可选地将所述电路设备与所述多个用于检测的设备中的可选择的一个连接; 以及外部编程装置，其使得所述链接元件选择所述多个检测装置中的给定的一个以与所述电路装置链接。

47. 发明授权

US4325384A Digitally controlled amplitude regulating device for electrocardiographic signals 失效
标题翻译：用于心电图信号的数字控制振幅调节装置
公开(公告)号：US4325384A
公开(公告)日：1982-04-20
申请号：US101495
申请日：1979-12-10
申请人： Reinhard Blaser , Klaus Olach , Max Schaldach
发明人： Reinhard Blaser , Klaus Olach , Max Schaldach
IPC分类号： A61B5/04 , H03G3/20 , A61N1/36
CPC分类号： H03G1/0088 , A61B5/04004 , H03G3/30 , Y10S128/902
摘要： A signal processing device composed of: a signal input for receiving an electrocardiographic signal containing a succession of QRS complexes; a signal output; a digitally operating unit having a transmission factor which is variable in discrete steps and connected between the signal input and output for supplying to the signal output a signal containing representations of the QRS complexes contained in the signal received by the signal input, with the relation between the amplitude of the signal at the signal output and the amplitude of the corresponding portions of the signal received by the signal input being proportional to the existing transmission factor of the digitally operating unit; and a transmission factor control unit connected to monitor the signal at the signal output for increasing the transmission factor of the digitally operating unit by one step in response to each appearance at the signal output of a QRS complex representation having a peak value between selected first and second threshold values and for reducing the transmission factor by one step in response to each appearance at the signal output of a QRS complex representation having a peak value greater than a selected third threshold value higher than each of the first and second threshold values.
摘要翻译：一种信号处理装置，包括：用于接收包含一系列QRS复合物的心电图信号的信号输入; 信号输出; 数字操作单元，其具有可在离散步长中变化并连接在信号输入和输出之间的传输因子，用于向信号输出提供包含由信号输入接收的信号中包含的QRS复合物的表示的信号，信号输出处的信号的幅度和由信号输入接收的信号的对应部分的幅度与数字操作单元的现有传输因子成正比; 以及传输因子控制单元，其连接以监测信号输出处的信号，以响应于QRS复数表示的信号输出处的每个出现增加数字操作单元的传输因子一步，所述QRS复数表示具有在所选择的第一和第第二阈值，并且用于响应于QRS复数表示的信号输出处的每个出现响应于大于比第一和第二阈值中的每一个阈值高的所选择的第三阈值的峰值，将传输因子减小一个步长。

48. 发明申请

US20090093855A1 HOUSING FOR A MEDICAL IMPLANT 有权
标题翻译：住院医疗植物
公开(公告)号：US20090093855A1
公开(公告)日：2009-04-09
申请号：US12336659
申请日：2008-12-17
申请人： Niels Mueller , Max Schaldach , Wiebke Neumann , Werner Uhrlandt , Marcel Starke
发明人： Niels Mueller , Max Schaldach , Wiebke Neumann , Werner Uhrlandt , Marcel Starke
IPC分类号： A61N1/375
CPC分类号： A61N1/3752 , Y10T29/49 , Y10T29/49016 , Y10T29/49144 , Y10T29/49146 , Y10T29/49147 , Y10T29/4998
摘要： Housing for medical implant, such as cardiac pacemaker, defibrillator, cardioverter, etc. Housing including hollow housing and terminal body attached to hollow housing, which has electrical terminal(s), situated in an externally accessible cavity of the terminal body, for connecting an electrode line, and terminal body including a base body made of electrically insulating plastic, connected to hollow housing and carries electrical supply lines and electrical contacts, which are electrically connected thereto, for the electrical terminal so that the contacts are connected via the electrical supply lines to electrical components in the interior of the hollow housing, electrical supply lines being welded to the electrical contacts and the electrical supply lines and electrical contacts, which are welded to one another, being embedded in the base body and thus fixed in their final position, and the base body being glued to the hollow housing an adhesive between hollow housing and terminal body.
摘要翻译：用于医疗植入物的住房，例如心脏起搏器，除颤器，心律转复器等。包括中空壳体和终端主体的壳体，其附接到中空壳体，其具有位于终端主体的外部可访问腔中的电气端子，用于连接电极线和端子体，其包括由电绝缘塑料制成的基体，连接到中空壳体并且承载与电端子电连接的电源线和电触点，使得触点经由电源线连接到中空壳体内部的电气部件，焊接到彼此焊接的电触头和供电线路和电触头的电源线嵌入基体并因此固定在其最终位置，并且基体在中空壳体和端子之间粘合剂粘合到中空壳体上身体。

49. 发明申请

US20070250120A1 ACTIVE IMPLANTABLE MEDICAL DEVICE WITH AT LEAST TWO DIAGNOSTIC AND/OR THERAPEUTIC FUNCTIONS 有权
标题翻译：具有至少两个诊断和/或治疗功能的活动可植入医疗装置
公开(公告)号：US20070250120A1
公开(公告)日：2007-10-25
申请号：US11738277
申请日：2007-04-20
申请人： Erhard FLACH , Wolfgang Geistert , Roland Jacobsen , Max Schaldach , Axel Ulbrich
发明人： Erhard FLACH , Wolfgang Geistert , Roland Jacobsen , Max Schaldach , Axel Ulbrich
IPC分类号： A61N1/18 , A61N1/36
CPC分类号： A61N1/3752 , A61N1/37 , A61N1/37211 , A61N1/375
摘要： An active medical implantable device with at least two diagnostic and/or therapeutic functions is constructed from separate active implant modules (2 to 7) which are adapted to the respective desired functions and can be coupled to each other.
摘要翻译：具有至少两个诊断和/或治疗功能的主动医学可植入装置由独立的有源植入模块（2至7）构成，其适用于各自所需的功能并可相互耦合。

50. 发明授权

US06917832B2 Stimulation apparatus 有权
标题翻译：刺激装置
公开(公告)号：US06917832B2
公开(公告)日：2005-07-12
申请号：US10167987
申请日：2002-06-12
申请人： Helmut Hutten , Max Schaldach, Jr.
发明人： Max Schaldach
IPC分类号： A61N1/37
CPC分类号： A61N1/3712
摘要： A stimulation apparatus, in particular for a human heart, has a stimulation unit, a signal detector and a control unit. The stimulation unit is adapted to deliver a stimulation pulse having a pulse duration, a pulse strength and a stimulation intensity. The signal detector is adapted to detect stimulation success on the basis of a picked-up signal. The control unit is connected to the stimulation unit and to the signal detector. It is designed such that the stimulation intensity varies depending upon the picked-up signal. A time-determining unit is provided that is at least indirectly connected to the control unit and with which a time difference between the delivery of a stimulation pulse and the pick-up of the picked-up signal or a signal feature of the picked-up signal can be detected.
摘要翻译：刺激装置，特别是对于人的心脏，具有刺激单元，信号检测器和控制单元。刺激单元适于传送具有脉冲持续时间，脉冲强度和刺激强度的刺激脉冲。信号检测器适于基于拾取信号来检测刺激成功。控制单元连接到刺激单元和信号检测器。其设计使得刺激强度根据拾取信号而变化。提供了一个时间确定单元，其至少间接地连接到控制单元，并且通过该时间差发送刺激脉冲的传送和拾取信号的拾取或拾取的信号特征之间的时间差可以检测到信号。

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