专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

US20100114210A1 IMPLANTABLE MEDICAL DEVICE LEAD CONNECTION ASSEMBLY 有权
标题翻译：可植入医疗设备引线连接组件
公开(公告)号：US20100114210A1
公开(公告)日：2010-05-06
申请号：US12363375
申请日：2009-01-30
申请人： William T. Donofrio , John E. Burnes , Paul G. Krause
发明人： William T. Donofrio , John E. Burnes , Paul G. Krause
IPC分类号： A61N1/375 , A61N1/39
CPC分类号： A61N1/3752 , H01R13/5224 , H01R24/58 , H01R2107/00 , H01R2201/12 , Y10S439/909
摘要： A lead connection assembly of an implantable medical device (IMD) may include at least two different types of electrical connectors. In some examples, the lead connection assembly may include first and second electrical connectors that have at least one of a different electrical contact arrangement, a different lead connection receptacle geometry or a different size than the first electrical connector. The first electrical connector may be electrically connected to a first therapy module that generates cardiac rhythm therapy that is delivered to a heart of a patient, and the second electrical connector may be electrically connected to a second therapy module that generates electrical stimulation that is delivered to a tissue site within the patient. The second electrical connector may be configured to be incompatible with a lead that delivers the cardiac rhythm therapy to the patient.
摘要翻译：可植入医疗装置（IMD）的引线连接组件可以包括至少两种不同类型的电连接器。在一些示例中，引线连接组件可以包括具有与第一电连接器不同的电接触布置，不同引线连接插座几何形状或不同尺寸中的至少一个的第一和第二电连接器。第一电连接器可以电连接到第一治疗模块，该第一治疗模块产生被递送到患者的心脏的心律疗法，并且第二电连接器可以电连接到产生电刺激的第二治疗模块，该电刺激被递送到患者内的组织部位。第二电连接器可以被配置为与将心律治疗递送给患者的引线不相容。

42. 发明申请

US20100198284A1 DETECTING AND TREATING ELECTROMECHANICAL DISSOCIATION OF THE HEART 有权
标题翻译：检测和治疗心脏的机械分离
公开(公告)号：US20100198284A1
公开(公告)日：2010-08-05
申请号：US12697019
申请日：2010-01-29
申请人： Xiaohong Zhou , Paul G. Krause , William T. Donofrio
发明人： Xiaohong Zhou , Paul G. Krause , William T. Donofrio
IPC分类号： A61N1/365 , A61N1/39
CPC分类号： A61N1/3627 , A61N1/0551 , A61N1/36114 , A61N1/36557 , A61N1/36564 , A61N1/3962
摘要： In some examples, an electromechanical disassociation state (EMD) of a heart of a patient can be treated by delivering electrical stimulation to a tissue site to at least one of modulate afferent nerve activity or inhibit efferent nerve activity upon determining that the heart is in an electromechanical dissociation state, where the tissue site comprises at least one of a nonmyocardial tissue site or a nonvascular cardiac tissue site. The delivery of electrical stimulation may effectively treat the EMD state of the heart, e.g., by enabling effective mechanical contraction of the heart. In another example, an electromechanical disassociation state of a heart of a patient can be treated by determining autonomic nervous system activity associated with a detected EMD state of the heart of a patient, and delivering electrical stimulation therapy to the patient based on the determined autonomic nervous system activity of the patient associated with the EMD state.
摘要翻译：在一些示例中，可以通过将电刺激递送至组织部位至少调整传入神经活动或抑制传出神经活动的至少一种来治疗患者心脏的机电解离状态（EMD），确定心脏处于机电解离状态，其中组织部位包含非心肌组织部位或非血管心脏组织部位中的至少一个。电刺激的递送可以有效地治疗心脏的EMD状态，例如通过使心脏有效的机械收缩。在另一个示例中，可以通过确定与患者的心脏的检测到的EMD状态相关联的自主神经系统活动来治疗患者的心脏的机电解离状态，并且基于确定的自主神经向患者输送电刺激疗法与EMD状态相关的患者的系统活动。

43. 发明授权

US09814886B2 Detecting and treating electromechanical dissociation of the heart 有权
公开(公告)号：US09814886B2
公开(公告)日：2017-11-14
申请号：US12697019
申请日：2010-01-29
申请人： Xiaohong Zhou , Paul G. Krause , William T. Donofrio
发明人： Xiaohong Zhou , Paul G. Krause , William T. Donofrio
IPC分类号： A61N1/00 , A61N1/362 , A61N1/36 , A61N1/39 , A61N1/05 , A61N1/365
CPC分类号： A61N1/3627 , A61N1/0551 , A61N1/36114 , A61N1/36557 , A61N1/36564 , A61N1/3962
摘要： In some examples, an electromechanical disassociation state (EMD) of a heart of a patient can be treated by delivering electrical stimulation to a tissue site to at least one of modulate afferent nerve activity or inhibit efferent nerve activity upon determining that the heart is in an electromechanical dissociation state, where the tissue site comprises at least one of a nonmyocardial tissue site or a nonvascular cardiac tissue site. The delivery of electrical stimulation may effectively treat the EMD state of the heart, e.g., by enabling effective mechanical contraction of the heart. In another example, an electromechanical disassociation state of a heart of a patient can be treated by determining autonomic nervous system activity associated with a detected EMD state of the heart of a patient, and delivering electrical stimulation therapy to the patient based on the determined autonomic nervous system activity of the patient associated with the EMD state.

44. 发明授权

US08473057B2 Shunt-current reduction housing for an implantable therapy system 有权
标题翻译：用于植入式治疗系统的分流电流还原壳体
公开(公告)号：US08473057B2
公开(公告)日：2013-06-25
申请号：US12609901
申请日：2009-10-30
申请人： William T. Donofrio , William J. Havel , Chris C. Christiansen , Paul G. Krause
发明人： William T. Donofrio , William J. Havel , Chris C. Christiansen , Paul G. Krause
IPC分类号： A61N1/375
CPC分类号： A61N1/375 , A61N1/08 , A61N1/36114 , A61N1/37 , A61N1/3718 , A61N1/37211 , A61N1/37288 , A61N1/3925 , A61N1/3962
摘要： Techniques for minimizing interference between first and second medical devices of a therapy system may include providing an outer housing for at least one of the medical devices that comprises an electrically insulative layer formed over at least the electrically conductive portions (e.g., an electrically conductive layer) of the housing, or providing an electrically insulative pouch around an electrically conductive housing of at least the first medical device. The electrically insulative layer or electrically insulative pouch may reduce or even eliminate shunt-current that flows into the medical device via the housing. The shunt-current may be generated by the delivery of electrical stimulation by the second medical device. In some examples, the techniques may also include shunt-current mitigation circuitry that helps minimize or even eliminate shunt-current that feeds into the first medical device via one or more electrodes electrically connected to the first medical device.
摘要翻译：用于最小化治疗系统的第一和第二医疗装置之间的干扰的技术可以包括提供用于至少一个医疗装置的外壳，其包括在至少导电部分（例如，导电层）上形成的电绝缘层，或者提供围绕至少第一医疗装置的导电外壳的电绝缘袋。电绝缘层或电绝缘袋可以减少甚至消除通过外壳流入医疗装置的分流电流。分流电流可以通过第二医疗装置的电刺激的传递来产生。在一些示例中，所述技术还可以包括分流电流缓解电路，其帮助最小化或甚至消除通过电连接到第一医疗设备的一个或多个电极馈入第一医疗设备的分流电流。

45. 发明申请

US20100114205A1 SHUNT-CURRENT REDUCTION HOUSING FOR AN IMPLANTABLE THERAPY SYSTEM 有权
标题翻译：用于可植入治疗系统的分流电流减少外壳
公开(公告)号：US20100114205A1
公开(公告)日：2010-05-06
申请号：US12609901
申请日：2009-10-30
申请人： William T. Donofrio , William J. Havel , Chris C. Christiansen , Paul G. Krause
发明人： William T. Donofrio , William J. Havel , Chris C. Christiansen , Paul G. Krause
IPC分类号： A61N1/375
CPC分类号： A61N1/375 , A61N1/08 , A61N1/36114 , A61N1/37 , A61N1/3718 , A61N1/37211 , A61N1/37288 , A61N1/3925 , A61N1/3962
摘要： Techniques for minimizing interference between first and second medical devices of a therapy system may include providing an outer housing for at least one of the medical devices that comprises an electrically insulative layer formed over at least the electrically conductive portions (e.g., an electrically conductive layer) of the housing, or providing an electrically insulative pouch around an electrically conductive housing of at least the first medical device. The electrically insulative layer or electrically insulative pouch may reduce or even eliminate shunt-current that flows into the medical device via the housing. The shunt-current may be generated by the delivery of electrical stimulation by the second medical device. In some examples, the techniques may also include shunt-current mitigation circuitry that helps minimize or even eliminate shunt-current that feeds into the first medical device via one or more electrodes electrically connected to the first medical device.
摘要翻译：用于最小化治疗系统的第一和第二医疗装置之间的干扰的技术可以包括提供用于至少一个医疗装置的外壳，其包括在至少导电部分（例如，导电层）上形成的电绝缘层，或者在至少第一医疗装置的导电外壳周围提供电绝缘袋。电绝缘层或电绝缘袋可以减少甚至消除通过外壳流入医疗装置的分流电流。分流电流可以通过第二医疗装置的电刺激的传递来产生。在一些示例中，所述技术还可以包括分流电流缓解电路，其帮助最小化或甚至消除通过电连接到第一医疗设备的一个或多个电极馈入第一医疗设备的分流电流。

46. 发明授权

US08612020B2 Implantable therapeutic nerve stimulator 有权
标题翻译：植入式治疗神经刺激器
公开(公告)号：US08612020B2
公开(公告)日：2013-12-17
申请号：US12570774
申请日：2009-09-30
申请人： William T. Donofrio
发明人： William T. Donofrio
IPC分类号： A61N1/04
CPC分类号： A61N1/0551 , A61N1/36114 , A61N1/37258 , A61N1/37282
摘要： A medical device includes an implantable device having a processor, a pulse generator and a first lead having first and second ends. The first end of the lead is operably and conductively coupled to the implantable device. A first electrode is operably and conductively coupled to the second end of the first lead. The first electrode has a sharp tip for transmitting and focusing a stimulation signal from the pulse generator to a tissue site.
摘要翻译：医疗装置包括具有处理器，脉冲发生器和具有第一和第二端的第一引线的可植入装置。引线的第一端可操作地和导电地耦合到可植入装置。第一电极可操作地并且导电地耦合到第一引线的第二端。第一电极具有尖锐的尖端，用于将来自脉冲发生器的刺激信号传输和聚焦到组织部位。

47. 发明授权

US08137277B2 Volumetric measurement and visual feedback of tissues 有权
标题翻译：组织的体积测量和视觉反馈
公开(公告)号：US08137277B2
公开(公告)日：2012-03-20
申请号：US13040730
申请日：2011-03-04
申请人： Jeffrey H. Nycz , Carlos E. Gil , William T. Donofrio , Jeetendra Subhash Bharadwaj
发明人： Jeffrey H. Nycz , Carlos E. Gil , William T. Donofrio , Jeetendra Subhash Bharadwaj
IPC分类号： A61B8/00
CPC分类号： A61B8/0875 , A61B8/4281 , A61B8/4472 , A61B8/56
摘要： Apparatus and methods for assessing tissue characteristics such as the dimensions and volume of an osteolytic lesion are disclosed. The apparatus may utilize ultrasound to provide visual and volumetric feedback related to a lesion or other tissue. Further the apparatus may be utilized to determine whether the lesion has been completely removed and filled with the appropriate amount of graft material.
摘要翻译：公开了用于评估组织特征如溶骨性病变的尺寸和体积的装置和方法。该装置可以利用超声波来提供与病变或其他组织相关的视觉和体积反馈。此外，该装置可以用于确定病变是否已被完全去除并且用适量的移植材料填充。

48. 发明授权

US07476233B1 Ultrasonic surgical system within digital control 有权
标题翻译：超声波外科系统数字控制
公开(公告)号：US07476233B1
公开(公告)日：2009-01-13
申请号：US09693621
申请日：2000-10-20
申请人： Eitan T. Wiener , William T. Donofrio
发明人： Eitan T. Wiener , William T. Donofrio
IPC分类号： H03L7/10
CPC分类号： A61B17/320068 , A61B2017/00026 , A61B2017/00725 , B06B1/0253 , B06B2201/76
摘要： An ultrasonic surgical system utilizes a digital control system to generate ultrasonic drive current for transducers that are located in a hand piece and are attached to a surgical scalpel or blade so as to vibrate the blade in response to the current. The digital control includes a digital signal processor (DSP) or microprocessor; a direct digital synthesis (DDS) device; a phase detection logic scheme, a control algorithm for seeking and maintaining resonance frequency; and design scheme that allows to regulate current, voltage, and power delivered to an ultrasonic device. The system allows the power versus load output curve to be tailored to a specific hand piece; the components of the digital system are much less sensitive to temperature variations; and the digital system provides increased flexibility in locating the resonance frequency of the blade and running diagnostic tests.
摘要翻译：超声外科系统利用数字控制系统为位于手持件中的换能器产生超声波驱动电流，并附接到外科手术刀或刀片，以便响应于电流使叶片振动。数字控制包括数字信号处理器（DSP）或微处理器; 直接数字合成（DDS）设备; 相位检测逻辑方案，用于寻找和维持共振频率的控制算法; 以及允许调节传递到超声波装置的电流，电压和功率的设计方案。该系统允许功率与负载输出曲线适合于特定的手部件; 数字系统的组件对温度变化不太敏感; 数字系统在确定叶片的共振频率和运行诊断测试方面提供了更大的灵活性。

49. 发明申请

US20080228072A1 Foreign Body Identifier 审中-公开
标题翻译：异物标识符
公开(公告)号：US20080228072A1
公开(公告)日：2008-09-18
申请号：US11687574
申请日：2007-03-16
申请人： Jeffrey H. Nycz , Carlos E. Gil , William T. Donofrio , Stanley Warren Olson , Jeetendra Bharadwaj
发明人： Jeffrey H. Nycz , Carlos E. Gil , William T. Donofrio , Stanley Warren Olson , Jeetendra Bharadwaj
IPC分类号： A61B8/00 , A61B17/00 , A61B17/08 , A61B5/05
CPC分类号： A61B5/05 , A61B5/4509 , A61B8/0833 , A61B8/4455 , A61B8/4472 , A61B8/56
摘要： A surgical instrument for the presence and/or location of a foreign body is disclosed. The surgical instrument is hand-held. In some embodiments, the surgical instrument includes transducers adapted for emitting and/or receiving signals. In such embodiments, the surgical instrument utilizes pulse-echo measurements to determine characteristics and/or location of the foreign body. In other embodiments, the surgical instrument includes a measurement circuit for detecting the presence and/or location of a foreign body by a change in the characteristics of the measurement circuit. The surgical instrument may be utilized to determine such things as the size of a foreign body, the orientation of a foreign body with respect to patient anatomy and/or another foreign body, and whether the foreign body has been completely removed.
摘要翻译：公开了一种用于异物的存在和/或位置的外科器械。手术器械是手持式的。在一些实施例中，外科器械包括适于发射和/或接收信号的换能器。在这样的实施例中，手术器械利用脉冲回波测量来确定异物的特征和/或位置。在其他实施例中，手术器械包括用于通过测量电路的特性的变化来检测异物的存在和/或位置的测量电路。外科器械可用于确定异物的尺寸，异物相对于患者解剖结构和/或另一异物的取向以及异物是否已被完全移除。

50. 发明授权

US07261106B2 Response testing for conscious sedation utilizing a cannula for support/response 有权
标题翻译：使用插管进行支持/反应的意识镇静的反应测试
公开(公告)号：US07261106B2
公开(公告)日：2007-08-28
申请号：US10670453
申请日：2003-09-25
申请人： William T. Donofrio
发明人： William T. Donofrio
IPC分类号： A61M16/00
CPC分类号： A61B5/6826 , A61B5/0002 , A61B5/0205 , A61B5/0488 , A61B5/0836 , A61B5/1106 , A61B5/1455 , A61B5/224 , A61B5/4821 , A61B5/6803 , A61B5/6815 , A61B5/6838 , A61M16/01 , A61M16/0666 , A61M16/0683 , A61M2016/0021 , A61M2205/3375 , A61M2205/3569 , A61M2205/3592 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/60 , A61M2230/63
摘要： A conscious sedation system and a cannula and response testing assemblage for a conscious sedation system. In one embodiment, a controller generates a request for a predetermined response from a patient and analyses at least a response made by the patient to the request to determine a level of sedation of the patient. A cannula is disposable on the face of the patient for monitoring the breathing of the patient. A request assembly communicates to the patient the request generated by the controller. A response assembly senses the response and communicates the response to the controller. At least a part of at least one of the request and response assemblies is supported by the cannula. In another embodiment, the cannula itself is used as the response assembly wherein the response is a breathing response of the patient to the request.
摘要翻译：有意义的镇静系统和用于清醒镇静系统的套管和反应测试组合。在一个实施例中，控制器生成来自患者的预定响应的请求，并且分析至少由患者对所述请求做出的响应以确定患者的镇静水平。套管在患者的表面上是一次性的，用于监测患者的呼吸。请求组件向患者传达由控制器产生的请求。响应组件感测响应并将响应传达给控制器。至少一个请求和响应组件的至少一部分由套管支撑。在另一个实施例中，套管本身被用作响应组件，其中响应是患者对该请求的呼吸响应。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式