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41. 发明申请

US20110118473A1 PROCESS FOR CONVERTING 9-DIHYDRO-13ACETYLBACCATIN III PACLITAXEL AND DOCETAXEL 审中-公开
标题翻译：转化9-二羟基-13-乙酰胆碱三磷脂和白藜芦醇的方法
公开(公告)号：US20110118473A1
公开(公告)日：2011-05-19
申请号：US12674632
申请日：2008-08-21
申请人： Jian Liu
发明人： Jian Liu
IPC分类号： C07D413/12 , C07D305/14
CPC分类号： C07D413/12 , C07D305/14
摘要： Processes for the preparation of docetaxel and paclitaxel or analogs from 9-dihydro-13-acetylbaccatin III via key intermediates (4), (5), (6), (6′), (8) and (8′) or via intermediate (12) as well as processes for the preparation of said intermediates are disclosed. Said processes involve, in particular, oxidation of the hydroxy group at C-10, reaction with side chain precursors and intramolecular isomerisation of the oxo at C-10 to produce the 9-oxo isomer. Paclitaxel and docetaxel are useful in the treatment of cancer. Formulae (I), (II), (III).
摘要翻译：通过关键中间体（4），（5），（6），（6'），（8）和（8'）制备多西他赛和紫杉醇或类似物从9-二氢-13-乙酰浆果赤霉素III或通过中间体（12）以及制备所述中间体的方法。所述方法特别涉及C-10处羟基的氧化，与侧链前体的反应以及在C-10处氧代的分子内异构化以产生9-氧代异构体。紫杉醇和多西紫杉醇可用于治疗癌症。式（I），（II），（III）。

42. 发明授权

US07872870B2 Heat dissipation device with fastener 有权
标题翻译：带扣件的散热装置
公开(公告)号：US07872870B2
公开(公告)日：2011-01-18
申请号：US12492139
申请日：2009-06-26
申请人： Jian Liu , Jing Zhang
发明人： Jian Liu , Jing Zhang
IPC分类号： H05K7/20 , F16B13/00
CPC分类号： H01L23/4093 , F28F3/02 , H01L2924/0002 , Y10T24/44026 , H01L2924/00
摘要： An electronic device comprises a printed circuit board, an electronic component mounted on the printed circuit board, a heat dissipation device dissipating heat generated by the electronic component and a plurality of wires on the printed circuit board. The heat dissipation device comprises a heat sink and a pair of fasteners securing the heat sink to the printed circuit board. Each fastener comprises a frame body having a gap defined at a top portion thereof. The wires in a form of a wire harness extend through the gap of the frame body and into the frame body.
摘要翻译：电子设备包括印刷电路板，安装在印刷电路板上的电子部件，散热由电子部件产生的热量和散布在印刷电路板上的多根导线的散热装置。散热装置包括散热器和将散热器固定到印刷电路板的一对紧固件。每个紧固件包括具有限定在其顶部部分的间隙的框体。线束形式的线材延伸穿过框架体的间隙并进入框架体。

43. 发明授权

US07869504B2 Coefficient scaling operational units 有权
标题翻译：系数缩放操作单位
公开(公告)号：US07869504B2
公开(公告)日：2011-01-11
申请号：US11262150
申请日：2005-10-28
申请人： Zhenguo Wang , Jian Liu , Tianyi Zhou , Xiaohai Zhao , Zhonghan Deng
发明人： Zhenguo Wang , Jian Liu , Tianyi Zhou , Xiaohai Zhao , Zhonghan Deng
IPC分类号： H04N7/12 , G06K9/00
CPC分类号： H04N19/42 , H04N19/12 , H04N19/126 , H04N19/136 , H04N19/18 , H04N19/61
摘要： Techniques for providing a coefficient scaling operational unit to perform the coefficient scaling computation for various image compression schemes are disclosed. To minimize multiple units, each for one image encoding/decoding scheme (e.g., MPEG4 and WMV9), a single coefficient scaling operational unit is designed to accommodate various standards. In one embodiment, the coefficient scaling operational unit comprises an arithmetic logic unit. The arithmetic logic unit operates in accordance with a formula involving multiplication and division. Parameters such as coefficients and quantization parameters are provided to perform the coefficient scaling operation.
摘要翻译：公开了用于提供系数缩放操作单元以执行各种图像压缩方案的系数缩放计算的技术。为了最小化多个单元，针对一个图像编码/解码方案（例如，MPEG4和WMV9），单个系数缩放操作单元被设计为适应各种标准。在一个实施例中，系数缩放操作单元包括算术逻辑单元。算术逻辑单元根据涉及乘法和除法的公式进行操作。提供诸如系数和量化参数的参数以执行系数缩放操作。

44. 发明授权

US07687603B2 Guanidinium delivery carriers 失效
标题翻译： Guanidinium输送载体
公开(公告)号：US07687603B2
公开(公告)日：2010-03-30
申请号：US11526224
申请日：2006-09-22
申请人： Gang Zhao , Lei Yu , Jian Liu , Chieko Kitaura , Xinghe Wang , Chris Castello
发明人： Gang Zhao , Lei Yu , Jian Liu , Chieko Kitaura , Xinghe Wang , Chris Castello
IPC分类号： A61K38/05
CPC分类号： C07K5/0215 , A61K31/555 , A61K47/641 , A61K47/645 , A61K49/085 , A61K49/146 , C07K7/02
摘要： Disclosed herein are transmembrane transporter compounds containing guanidinium groups. Also disclosed herein are methods for transporting a biologically active moiety across a biological membrane using the transmembrane transporter compounds. Particularly, this invention provides a method for the delivery of a biologically active moiety across the biological membranes of such membranes as endothelial tissues.
摘要翻译：本文公开了含有胍基的跨膜转运体化合物。本文还公开了使用跨膜转运体化合物在生物膜上输送生物活性部分的方法。特别地，本发明提供了一种在诸如内皮组织之类的膜的生物膜上递送生物活性部分的方法。

45. 发明申请

US20100067746A1 OPTICAL MOTION SENSING PROCESS 失效
标题翻译：光学运动感应过程
公开(公告)号：US20100067746A1
公开(公告)日：2010-03-18
申请号：US11720828
申请日：2006-04-27
申请人： Jian Liu , Shuwei Hou
发明人： Jian Liu , Shuwei Hou
IPC分类号： G06K9/00
CPC分类号： G06F3/038 , G06F3/03543
摘要： A motion sensing process senses a mouse moving relative to a surface by taking a reference image and a sample image of the surface. The process shifts the reference image to neighboring pixel positions arranged in certain patterns and compares the sample image with the reference image at its original pixel position at the shifted pixel positions. A motion vector describing a displacement of the object with respect to the surface is generated from such comparisons. In one embodiment, the pattern includes the original pixel position and neighboring pixel position arranged five rows and five columns with the total number of the pixel positions less than twenty five. In another embodiment, the process selects one of four elongated patterns based on the orientation of a predicted motion vector. In yet another specific embodiment, the process selects one of eight directional patterns based on the direction of the predicted motion vector.
摘要翻译：运动感测过程通过拍摄表面的参考图像和样本图像来感测鼠标相对于表面的移动。该处理将参考图像移动到以某些图案排列的相邻像素位置，并将样本图像与其移位像素位置处的原始像素位置处的参考图像进行比较。从这样的比较生成描述物体相对于表面的位移的运动矢量。在一个实施例中，图案包括原始像素位置和布置成五行和五列的相邻像素位置，其中像素位置的总数小于二十五。在另一个实施例中，该过程基于预测运动矢量的取向来选择四个细长图案之一。在另一具体实施例中，该过程基于预测运动矢量的方向选择八个方向图中的一个。

46. 发明申请

US20100051230A1 FAN HOLDER 失效
标题翻译：风扇座
公开(公告)号：US20100051230A1
公开(公告)日：2010-03-04
申请号：US12202403
申请日：2008-09-01
申请人： Jian Liu , Jun Luo
发明人： Jian Liu , Jun Luo
IPC分类号： F28F7/00
CPC分类号： H01L23/427 , H01L23/467 , H01L2924/0002 , H01L2924/00
摘要： A fan holder used to secure a fan to a heat dissipation device, includes a main body for mounting the fan thereon, a pair of blocking wings and a pair of baffle walls extending from the main body to define a space for receiving the fan therein. The blocking wings each include a pair of locking protrusions engaging in the fan to prevent the fan from moving vertically. The baffle walls each includes a pair of blocking flanges fittingly received in cutouts defied in the fan to prevent the fan from moving horizontally along a lateral direction of the fan holder. The baffle walls engage with front and rear sides of the fan for preventing the fan from moving along a front-to-rear direction.
摘要翻译：用于将风扇固定到散热装置的风扇架包括：用于将风扇安装在其上的主体，一对阻挡翼和从主体延伸的一对挡板，以限定用于在其中容纳风扇的空间。阻挡翼各自包括一对接合在风扇中的锁定突起，以防止风扇垂直移动。挡板壁每个包括一对阻挡凸缘，其适合地接收在风扇中的缺口中，以防止风扇沿风扇保持器的横向方向水平移动。挡板壁与风扇的前侧和后侧接合，以防止风扇沿着前后方向移动。

47. 发明授权

US07590155B2 Hybrid high power laser to achieve high repetition rate and high pulse energy 有权
标题翻译：混合大功率激光器实现高重复率和高脉冲能量
公开(公告)号：US07590155B2
公开(公告)日：2009-09-15
申请号：US11198078
申请日：2005-08-04
申请人： Jian Liu
发明人： Jian Liu
IPC分类号： H01S3/30
CPC分类号： H01S3/06754 , G02B6/4214 , H01S3/0632 , H01S3/06708 , H01S3/08009 , H01S3/094007 , H01S3/094019 , H01S3/0941 , H01S3/1618 , H01S3/2308 , H01S2301/02 , H01S2301/03
摘要： A fiber laser cavity that provides a new pulse shaping and spectral shaping technique is disclosed in this invention to achieve the purpose of resolving the difficulties arising from the issues related to Q-switched solid state lasers. The laser system achieves high repetition rate (1 kHz-100 kHz) and high pulse-to-pulse energy stability with small timing jitter of the laser pulses and scalable to the Joule pulse energy level. The laser system of this invention employs new approach with a hybrid fiber/waveguide master Oscillator-High Power Amplifier (MOPA) laser system in combination with the pulse shaping technology that allows not only to scale the fiber laser pulse energy to the multi-Joule level with high pulse-to-pulse energy stability but also achieve precise control of laser pulse timing jitter in a scale of
摘要翻译：在本发明中公开了提供新的脉冲整形和频谱整形技术的光纤激光腔，以实现解决与Q开关固体激光器有关的问题所引起的困难的目的。激光系统实现了高重复率（1 kHz-100 kHz）和高脉冲到脉冲能量稳定性，激光脉冲的定时抖动小，并可扩展到焦耳脉冲能级。本发明的激光系统采用混合光纤/波导主振荡器 - 大功率放大器（MOPA）激光系统的新方法，与脉冲整形技术相结合，不仅可以将光纤激光脉冲能量缩放到多焦耳级具有高的脉冲到脉冲能量稳定性，但也可以实现精确控制激光脉冲定时抖动，其规模小于100 ps，比相同参数达到500-1000的Q开关系统至少要5到10倍精度 ps范围。

48. 发明申请

US20090105118A1 Preparation and applications of novel complexes made by gamma-polyglutamic acid and cisplatin 审中-公开
标题翻译：由γ-聚谷氨酸和顺铂制备的新型复合物的制备和应用
公开(公告)号：US20090105118A1
公开(公告)日：2009-04-23
申请号：US11975507
申请日：2007-10-19
申请人： Haifeng Ye , Zirong Wu , Jing Huang , Li Jin , Rongzhang Hu , Chengliang He , Jian Liu
发明人： Haifeng Ye , Zirong Wu , Jing Huang , Li Jin , Rongzhang Hu , Chengliang He , Jian Liu
IPC分类号： A61K38/02 , C07K2/00 , A61P35/00
CPC分类号： A61K38/02 , A61K33/24 , A61K47/645 , A61K2300/00
摘要： A series of complexes made by γ-polyglutamic acid (γ-PGA) and cisplatin, their preparation and applications in biomedical field, specifically in cancer treatment. The complexes may be made by binding free cisplatin on small molecule γ-PGA through the reaction between carboxylic group of γ-PGA and Cl of cisplatin. The complexes show effective anticancer effect and are easy and cost effective to prepare.
摘要翻译：由γ-聚谷氨酸（γ-PGA）和顺铂制成的一系列复合物，它们在生物医学领域的应用，特别是癌症治疗。复合物可以通过γ-PGA的羧基与顺铂的C1反应在小分子γ-PGA上结合游离顺铂来制备。复合物显示出有效的抗癌作用，并且制备容易且成本有效。

49. 发明申请

US20090061627A1 METHOD FOR PRODUCING A METAL BACKSIDE CONTACT OF A SEMICONDUCTOR COMPONENT, IN PARTICULAR, A SOLAR CELL 失效
标题翻译：用于制造特别是太阳能电池的半导体元件的金属背面接触的方法
公开(公告)号：US20090061627A1
公开(公告)日：2009-03-05
申请号：US12202123
申请日：2008-08-29
申请人： Roland Trassl , Jian Liu , Stephan Wieder , Juergen Henrich , Gerhard Rist
发明人： Roland Trassl , Jian Liu , Stephan Wieder , Juergen Henrich , Gerhard Rist
IPC分类号： H01L21/768 , H01L21/677
CPC分类号： H01L31/022425 , Y02E10/50
摘要： The present invention relates to a method for manufacturing a backside contact of a semiconductor component, in particular, of a solar cell, comprising a metallic layer on the backside of a substrate in a vacuum treatment chamber, and the use of a vacuum treatment system for performing said method. Through this method and its use, in particular silicon based solar cells, can be provided with a back contact in a simple manner in a continuous process sequence, wherein the process sequence can be provided particularly efficient and economical, since no handling systems for rotating the substrate are required, and in particular silk screening steps can be dispensed with.
摘要翻译：本发明涉及一种用于制造半导体部件，特别是太阳能电池的背面接触的方法，所述太阳能电池在真空处理室中在基板的背面上包括金属层，并且使用真空处理系统执行所述方法。通过这种方法及其使用，特别是硅基太阳能电池可以以连续的工艺顺序以简单的方式提供背面接触，其中可以提供特别有效和经济的工艺顺序，因为没有用于旋转基材是必需的，特别是可以省去丝印步骤。

50. 发明申请

US20090041062A1 FIBER-BASED TUNABLE LASER 审中-公开
标题翻译：光纤激光器
公开(公告)号：US20090041062A1
公开(公告)日：2009-02-12
申请号：US12100669
申请日：2008-04-10
申请人： Jian Liu
发明人： Jian Liu
IPC分类号： H01S3/10 , H01S3/30
CPC分类号： H01S3/0057 , G02B6/29361 , G02B6/29395 , G02B6/4215
摘要： A fiber-based tunable laser includes a spectrum-expansion device comprising a micro structured fiber configured to receive a pump laser pulse having a first band width and a first pulse energy, and to produce a spectrally expanded laser pulse having a second band width at least two times broader than the first band width. The fiber-based tunable laser also includes a combiner that can couple the pump laser pulse into the spectrum-expansion device and a filter that can select a signal laser wavelength within the second band width and to produce a signal laser pulse at the signal laser wavelength. The signal laser pulse has a third band width narrower than the second band width. One or more cavity fibers allow propagation of the spectrally expanded laser pulse and the signal laser pulse between the spectrum-expansion device and the filter.
摘要翻译：基于光纤的可调谐激光器包括频谱扩展装置，其包括被配置为接收具有第一带宽和第一脉冲能量的泵浦激光脉冲的微结构光纤，并且产生具有至少第二带宽的光谱扩展的激光脉冲比第一个带宽宽两倍。基于光纤的可调谐激光器还包括可以将泵激光脉冲耦合到频谱扩展装置中的组合器和可以在第二带宽内选择信号激光波长并且以信号激光波长产生信号激光脉冲的滤波器。信号激光脉冲具有比第二带宽窄的第三带宽。一个或多个空腔光纤允许频谱扩展的激光脉冲和信号激光脉冲在频谱扩展装置和滤波器之间传播。

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