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41. 发明授权

US09180084B2 Cassia derivatives 有权
标题翻译：决明子衍生物
公开(公告)号：US09180084B2
公开(公告)日：2015-11-10
申请号：US14125190
申请日：2012-05-17
申请人： Carole A. Lepilleur , Dennis Malaba , John J. Mullay , Denise W. Rafferty , Duane G. Krzysik , Xin Liu , Eric H. Anderson
发明人： Carole A. Lepilleur , Dennis Malaba , John J. Mullay , Denise W. Rafferty , Duane G. Krzysik , Xin Liu , Eric H. Anderson
IPC分类号： A61K8/73 , A61Q5/02 , A61Q5/06 , C08B37/00 , C08L5/00 , A61Q5/12 , A61K8/97 , C11D3/22 , A61Q5/00 , A61Q5/10 , A61Q7/00 , A61Q11/00 , A61Q15/00 , A61Q17/04 , A61Q19/02 , A61Q19/04 , A61Q19/06 , A61Q19/08
CPC分类号： A61K8/737 , A61K8/97 , A61Q5/006 , A61Q5/02 , A61Q5/06 , A61Q5/10 , A61Q5/12 , A61Q7/00 , A61Q11/00 , A61Q15/00 , A61Q17/04 , A61Q19/02 , A61Q19/04 , A61Q19/06 , A61Q19/08 , C08B37/0087 , C08L5/00 , C11D3/225
摘要： This invention relates to a cationically and amphiphilically modified polygalactomannan having repeating units with an average D-mannosyl to D-galactosyl residue ratio of at least 5 to 1 and to compositions containing same. A portion of the hydrogen atoms of hydroxyl groups situated on the mannosyl and galactosyl residues of the galactomannan are replaced with an amphiphilic and a cationic substituent.
摘要翻译：本发明涉及具有平均D-甘露糖基至D-半乳糖基残基比例至少为5:1的重复单元的阳离子和两亲改性的聚半乳甘露聚糖以及含有它们的组合物。位于半乳甘露聚糖的甘露糖基和半乳糖基残基的羟基的一部分氢原子被两亲性和阳离子取代基取代。

42. 发明授权

US08990242B2 Enhanced query suggestions in autosuggest with corresponding relevant data 有权
标题翻译：自动提示中增强的查询建议与相应的相关数据
公开(公告)号：US08990242B2
公开(公告)日：2015-03-24
申请号：US13209891
申请日：2011-08-15
申请人： Asad Mohiuddin , Glen Joseph Fernandes , Hussein Mohamed Mehanna , Tabreez Govani , Ashwin Satyanarayana , Xin Liu
发明人： Asad Mohiuddin , Glen Joseph Fernandes , Hussein Mohamed Mehanna , Tabreez Govani , Ashwin Satyanarayana , Xin Liu
IPC分类号： G06F17/30
CPC分类号： G06F17/3064 , G06F17/30646
摘要： Methods and computer-storage media having computer-executable instructions embodied thereon that facilitate determining enhanced query suggestions are provided. A plurality of query suggestions responsive to a user query are received. Items of data corresponding to the query suggestions are received. Based on the received query suggestions and the received items of data, enhanced query suggestions are determined. In embodiments, an enhanced query suggestion includes one or more items of data related to a respective query suggestion. A user may select at least a portion of an enhanced query suggestion. In embodiments, selection of a portion of an enhanced query suggestion provides additional information.
摘要翻译：提供了具有便于确定增强的查询建议的其上包含有计算机可执行指令的方法和计算机存储介质。接收响应于用户查询的多个查询建议。收到与查询建议相对应的数据项。根据收到的查询建议和收到的数据项，确定增强查询建议。在实施例中，增强查询建议包括与相应查询建议相关的一个或多个数据项。用户可以选择增强查询建议的至少一部分。在实施例中，增强查询建议的一部分的选择提供附加信息。

43. 发明授权

US08695446B2 System and method for detecting pluggage in a conduit for delivery of solids and carrier gases to a flowing gas stream 有权
标题翻译：用于检测用于将固体和载气输送到流动气流的管道中的行李的系统和方法
公开(公告)号：US08695446B2
公开(公告)日：2014-04-15
申请号：US13003138
申请日：2009-07-08
申请人： Xin Liu , Jon E. Miller
发明人： Xin Liu , Jon E. Miller
IPC分类号： G01N19/00
CPC分类号： B01D53/83 , B01D53/0446 , B01D2251/404 , B01D2251/604 , B01D2257/2045 , B01D2257/302 , B01D2257/602 , Y10T137/8158
摘要： A process and system for detecting pluggage in a conduit that is feeding a solid and carrier gas to a flowing gas.
摘要翻译：一种用于检测导管中的行李的过程和系统，其将固体和载气供给流动的气体。

44. 发明申请

US20140021049A1 MICROFLUIDIC SYSTEMS 有权
标题翻译：微流体系统
公开(公告)号：US20140021049A1
公开(公告)日：2014-01-23
申请号：US13725459
申请日：2012-12-21
申请人： Tony R. JOAQUIM , Lewis Joe Stafford , Ross Stewart Chambers , Xin Liu , Clive Adrian Smith , Xin Li , Graeme Whyte
发明人： Tony R. JOAQUIM , Lewis Joe Stafford , Ross Stewart Chambers , Xin Liu , Clive Adrian Smith , Xin Li , Graeme Whyte
IPC分类号： G01N27/447
CPC分类号： G01N27/44791 , B01L3/0268 , B01L3/502784 , B01L2200/0652 , B01L2200/0673 , B01L2400/0415 , B01L2400/043 , G01N15/1484 , G01N2015/149
摘要： A flow cell for a microfluidic device can include a chamber, first microfluidic entry and exit channels, second microfluidic entry and exit channels, a first electrode, and a second electrode. A microfluidic device can include a microfluidic channel, a laser to excite fluorescent material, and a detector to detect fluorescence emission. Methods of merging a droplet from an emulsion in to a second stream of fluid and of detecting a content of a droplet in a stream are further disclosed.
摘要翻译：用于微流体装置的流动池可以包括室，第一微流体入口和出口通道，第二微流体入口和出口通道，第一电极和第二电极。微流体装置可以包括微流体通道，激发荧光材料的激光器和检测器以检测荧光发射。进一步公开了将液滴从乳液合并到第二流体流中并且检测流中的液滴含量的方法。

45. 发明授权

US08523455B2 Ruggedized fiber optic connector assembly 有权
公开(公告)号：US08523455B2
公开(公告)日：2013-09-03
申请号：US12534796
申请日：2009-08-03
申请人： James P. Luther , Thomas Theuerkorn , Xin Liu
发明人： James P. Luther , Thomas Theuerkorn , Xin Liu
IPC分类号： G02B6/38 , G02B6/42
CPC分类号： G02B6/3869 , G02B6/3887
摘要： A ruggedized fiber optic connector assembly includes a substantially hollow plug housing; and a glue body disposed within the substantially hollow plug housing; wherein the glue body includes a first portion that is configured to engage and retain an optical cable comprising an optical fiber and one or more strength members; wherein the glue body includes a second portion that is configured to engage and retain a connector sub-assembly comprising an optical ferrule; wherein the second portion of the glue body includes a pair of opposed snap hooks that are configured to engage a corresponding pair of opposed recesses of the connector sub-assembly; and wherein the optical fiber and the optical ferrule are optically coupled.

46. 发明授权

US08513981B2 Squelch detection method and circuit using rectifying circuit for detecting out-of-band signal 有权
标题翻译：静噪检测方法和电路采用整流电路检测带外信号
公开(公告)号：US08513981B2
公开(公告)日：2013-08-20
申请号：US13316737
申请日：2011-12-12
申请人： Xin Liu , Arvind Bomdica
发明人： Xin Liu , Arvind Bomdica
IPC分类号： H03K5/22
CPC分类号： H03F3/45179 , H03F3/45632 , H03F3/505 , H03F2200/78 , H03F2203/45394 , H03F2203/45418 , H03F2203/45478 , H03F2203/45562 , H03F2203/45648
摘要： A circuit for detecting out-of-band signals is disclosed. In one embodiment, the circuit includes a first differential circuit configured to level shift and positively rectify a differential input signal to produce a first output component of a differential output signal. The first differential circuit is further configured to generate and provide a common mode voltage of the differential input signal as a second component of the differential output signal. The circuit further includes a second differential circuit configured to level shift and output first and second fixed voltages based on an input reference voltage and a ground voltage. The circuit is configured to provide the differential output signal and the first and second fixed voltages to an indicator circuit configured to assert an indication responsive to detecting that a differential voltage of the differential output signal is greater than a differential voltage of the first and second fixed voltages.
摘要翻译：公开了一种用于检测带外信号的电路。在一个实施例中，电路包括第一差分电路，其被配置为对差分输入信号进行电平移位和正整流以产生差分输出信号的第一输出分量。第一差分电路还被配置为产生并提供差分输入信号的共模电压作为差分输出信号的第二分量。该电路还包括第二差分电路，其被配置为基于输入参考电压和接地电压来电平移位和输出第一和第二固定电压。电路被配置为将差分输出信号和第一和第二固定电压提供给指示器电路，该指示器电路被配置为响应于检测到差分输出信号的差分电压大于第一和第二固定的差分电压而断言指示电压。

47. 发明申请

US20130195338A1 INSTRUMENT-BASED IMAGE REGISTRATION FOR FUSING IMAGES WITH TUBULAR STRUCTURES 有权
标题翻译：基于仪器的图像注册，用于用管状结构融合图像
公开(公告)号：US20130195338A1
公开(公告)日：2013-08-01
申请号：US13640752
申请日：2011-03-29
申请人： Di Xu , Xin Liu , Luis Felipe Gutierrez
发明人： Di Xu , Xin Liu , Luis Felipe Gutierrez
IPC分类号： G06K9/00
CPC分类号： G06K9/0014 , A61B6/03 , A61B6/12 , A61B6/4441 , A61B6/466 , A61B6/5235 , A61B6/547 , G06T7/33 , G06T2207/10081 , G06T2207/10116 , G06T2207/30061
摘要： A system and method for registering three-dimensional images with two-dimensional intra-operative images includes segmenting (24) a tubular structured organ in a three-dimensional image of the organ, and projecting (26) the three-dimensional image of the organ into two-dimensional space to provide a projected image. A medical instrument depicted in a two-dimensional image of the medical instrument is segmented (28). A similarity score is computed between the projected image and a shape of the medical instrument depicted in the two-dimensional image to determine a best match. The projected image is registered (30) to the two-dimensional image based on the best match.
摘要翻译：用于用二维手术图像记录三维图像的系统和方法包括在器官的三维图像中分割（24）管状结构器官，并且突出（26）器官的三维图像进入二维空间以提供投影图像。分割医疗器械的二维图像中描绘的医疗器械（28）。在投影图像和二维图像中描绘的医疗器械的形状之间计算相似度得分以确定最佳匹配。基于最佳匹配将投影图像记录（30）到二维图像。

48. 发明授权

US08476458B2 Methods and compositions for modulating P300/CBP activity 有权
公开(公告)号：US08476458B2
公开(公告)日：2013-07-02
申请号：US12665751
申请日：2008-06-19
申请人： Ronen Marmorstein , Xin Liu , Philip A. Cole , Ling Wang , Erin M. Bowers , David J. Meyers , Chandrani Mukherjee
发明人： Ronen Marmorstein , Xin Liu , Philip A. Cole , Ling Wang , Erin M. Bowers , David J. Meyers , Chandrani Mukherjee
IPC分类号： C07D231/00 , C07D231/06 , C07D307/00 , C07D317/00 , C07D323/02
CPC分类号： A61K31/5585 , A61K31/4015 , A61K31/402 , A61K31/4025 , C07D405/06 , C12N9/1029 , C12Q1/48 , C12Y203/01048 , C40B30/02 , G01N2333/91057 , G01N2500/04 , Y02A90/26
摘要： The present invention relates to a method for identifying compounds that modulate the activity of p300/CBP. Compounds of the invention are identified by designing or screening for a compound which binds to at least one amino acid residue of the newly identified lysine-CoA inhibitor binding site, L1 loop, electronegative pocket, or electronegative groove of the HAT domain of p300/CBP and testing the compound for its ability to modulate the activity of p300/CBP. Compositions and methods for preventing or treating diseases or disorders associated with p300/CBP are also provided as is a method for producing a semi-synthetic HAT domain.

49. 发明申请

US20130129639A1 Cassia Derivatives 审中-公开
标题翻译：决明子衍生物
公开(公告)号：US20130129639A1
公开(公告)日：2013-05-23
申请号：US13695135
申请日：2011-04-28
申请人： Eric H. Anderson , Carole A. Lepilleur , Dennis N. Malaba , John J. Mullay , Denise W. Rafferty , Duane G. Krzysik , Xin Liu
发明人： Eric H. Anderson , Carole A. Lepilleur , Dennis N. Malaba , John J. Mullay , Denise W. Rafferty , Duane G. Krzysik , Xin Liu
IPC分类号： A61K31/736 , A61K8/73 , A61Q15/00 , A61Q5/00 , A61Q1/02 , A61Q17/04 , A61Q5/06 , A61Q5/08 , A61Q19/02 , A61Q11/00 , A61P31/10 , A61K8/92 , A61Q5/02 , A61Q5/12 , A61Q19/10 , C08B37/00
CPC分类号： C08B37/0087 , A61K8/737 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q19/00 , C08L5/00 , C11D3/227
摘要： This invention relates to a cationically and hydrophobically modified polygalactomannan having repeating units with a D-mannosyl to D-galactosyl residue ratio of at least 5 to 1 and to compositions containing same. A portion of the hydrogen atoms of hydroxyl groups situated on the mannosyl and galactosyl residues of the galactomannan are replaced with a hydrophobic substituent and a cationic substituent.
摘要翻译：本发明涉及具有D-甘露糖基至D-半乳糖基残基比例至少为5:1的重复单元的阳离子和疏水改性的聚半乳甘露聚糖和含有它们的组合物。位于半乳甘露聚糖的甘露糖基和半乳糖基残基上的羟基的一部分氢原子被疏水取代基和阳离子取代基取代。

50. 发明申请

US20130073568A1 RANKING STRUCTURED OBJECTS AND ACTIONS ON A SOCIAL NETWORKING SYSTEM 审中-公开
标题翻译：对社会网络系统的结构化对象和行为进行排序
公开(公告)号：US20130073568A1
公开(公告)日：2013-03-21
申请号：US13239343
申请日：2011-09-21
申请人： Vladimir Federov , Xin Liu , David Michael Proudfoot , Wei Xu
发明人： Vladimir Federov , Xin Liu , David Michael Proudfoot , Wei Xu
IPC分类号： G06F17/30
CPC分类号： G06Q50/01 , G06F16/9535 , G06Q30/0269
摘要： A social networking system includes a mechanism for integrating user actions on objects outside of the social networking system in the social graph. External system operators include widgets that, when executed by user devices, record user interactions that correspond to a defined structure of actions and objects. Information about the actions and the objects is gathered from external systems as users of the social networking system interact with the external systems. Content items are ranked according to the information about the actions and the objects as well as preferences of the viewing users.
摘要翻译：社交网络系统包括将社交网络系统外的对象的用户动作整合到社交图中的机制。外部系统操作员包括小部件，当由用户设备执行时，记录与定义的动作和对象结构相对应的用户交互。关于动作和对象的信息是从外部系统收集的，因为社交网络系统的用户与外部系统进行交互。根据关于动作和对象的信息以及观看用户的偏好来对内容项进行排名。

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