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41. 发明授权

US08369934B2 Contact over-torque with three-dimensional anatomical data 有权
标题翻译：接触过扭矩与三维解剖数据
公开(公告)号：US08369934B2
公开(公告)日：2013-02-05
申请号：US12830708
申请日：2010-07-06
申请人： Raju R. Viswanathan
发明人： Raju R. Viswanathan
IPC分类号： A61B5/055 , A61B19/00
CPC分类号： A61B1/00158 , A61B5/042 , A61B5/06 , A61B5/1076 , A61B5/6885 , A61B34/73
摘要： A method is provided for establishing contact of a medical device against a three-dimensional surface geometry within a subject body, the method comprising obtaining a three-dimensional tissue surface geometry of an anatomical region within the subject body, obtaining a target location on the surface for the device to contact, determining local surface geometry information in a neighborhood of the target location, and using this information to determine a change of at least one control variable for effecting an over-torque of the medical device to enhance contact of the device with the target surface.
摘要翻译：提供了一种用于建立医疗装置与受试者体内的三维表面几何形状的接触的方法，所述方法包括获得所述对象体内的解剖区域的三维组织表面几何形状，获得所述表面上的目标位置用于使所述设备接触，确定所述目标位置附近的局部表面几何信息，以及使用所述信息来确定至少一个控制变量的变化，以实现所述医疗设备的过扭矩以增强所述设备与目标表面。

42. 发明授权

US08348858B2 Stent delivery guide wire 有权
标题翻译：支架输送导丝
公开(公告)号：US08348858B2
公开(公告)日：2013-01-08
申请号：US11325680
申请日：2006-01-04
申请人： Raju R. Viswanathan , Jonathan C. Sell
发明人： Raju R. Viswanathan , Jonathan C. Sell
IPC分类号： A61B5/00
CPC分类号： A61M25/09 , A61F2/958 , A61F2002/9583 , A61F2210/009 , A61M25/0127
摘要： A guide wire for magnetically navigating a medical device through in a subject's body comprising an elongate wire having a proximal and distal end, a portion adjacent the distal end that is more flexible than the more proximal portions of the elongate wire, and a first magnetically responsive element on the distal end of the elongate wire. The guide wire further comprises one or more magnetically responsive elements spaced apart from the first magnetically responsive element and disposed on the more flexible portion of the elongate wire. The guide wire provides for bending or deflecting the distal end of the stent, to provide easier navigation of the distal end of the guide wire and the stent through the vasculature of a subject body.
摘要翻译：一种用于磁性导航医疗装置通过被检体的引导线，包括具有近端和远端的细长线，与远端相邻的部分比细长线的较近端部更柔性，以及第一磁性响应细长丝线的远端上的元件。引导线还包括一个或多个与第一磁响应元件间隔开的并且设置在细长线的更柔性部分上的磁响应元件。引导线用于弯曲或偏转支架的远端，以便通过主体的脉管系统提供引导线和支架远端的更容易的导航。

43. 发明授权

US07560923B2 Signal acquisition and processing method and apparatus for magnetic resonance imaging 失效
公开(公告)号：US07560923B2
公开(公告)日：2009-07-14
申请号：US11981865
申请日：2007-10-31
申请人： Raju R. Viswanathan
发明人： Raju R. Viswanathan
IPC分类号： G01V3/00
CPC分类号： G01R33/3808 , G01R33/4833
摘要： A method and apparatus are disclosed for Magnetic Resonance Imaging using specialized signal acquisition and processing techniques for image reconstruction with a generally inhomogeneous static magnetic field. New signal processing methods for image reconstruction and for minimizing dephasing effects are disclosed. Imaging systems with smaller static magnetic field strengths and smaller hardware demands than those with homogeneous static magnetic fields are provided, leading to significant reductions in system size and cost as compared to standard MRI systems. Such systems can also exploit imaging coils having high Signal-to-Noise-Ratio (SNR), including those made from Carbon nanotube conductors, leading to further imaging system efficiencies.

44. 发明申请

US20090138009A1 MAGNETICALLY GUIDED ENERGY DELIVERY APPARATUS 有权
标题翻译： MAGNETICALLY指导能源交付工具
公开(公告)号：US20090138009A1
公开(公告)日：2009-05-28
申请号：US12265013
申请日：2008-11-05
申请人： Raju R. Viswanathan , Gareth T. Munger , Ashwini K. Pandey , Christopher D. Minar
发明人： Raju R. Viswanathan , Gareth T. Munger , Ashwini K. Pandey , Christopher D. Minar
IPC分类号： A61B18/14
CPC分类号： A61M25/09 , A61B18/1492 , A61B2018/00101 , A61B2034/2051 , A61M2025/09183
摘要： This invention describes an energy delivery apparatus for delivering electrical energy at a target location, said energy delivery apparatus being usable in combination with a magnetic field and comprising an electrical conductor having a substantially elongated configuration; an electrode for delivering electrical energy at the target location, with the electrode being electrically coupled to the electrical conductor and having an exposed surface with at least a portion of the exposed surface having one of its principal radii of curvature smaller than 0.35 mm; an insulating dielectric coating along a substantial portion of the length of the electrical conductor, with the dielectric coating having a dielectric constant smaller than about 3; at least one guiding element mounted to the electrical conductor, with at least one of the guiding elements including a magnetically responsive material. The magnetic field is used to move the guiding element in order to position the electrode substantially adjacent to the target location.
摘要翻译：本发明描述了一种用于在目标位置传送电能的能量输送装置，所述能量输送装置可与磁场结合使用并且包括具有基本细长构型的电导体; 用于在目标位置处传送电能的电极，其中电极电耦合到电导体并且具有暴露表面，其中暴露表面的至少一部分具有小于0.35mm的其主曲率半径之一; 绝缘电介质涂层沿电导体的长度的大部分，电介质涂层的介电常数小于约3; 安装到电导体的至少一个引导元件，其中至少一个引导元件包括磁响应材料。磁场用于移动引导元件，以使电极基本上邻近目标位置。

45. 发明申请

US20080169815A1 Method and apparatus for high-gain magnetic resonance imaging 失效
公开(公告)号：US20080169815A1
公开(公告)日：2008-07-17
申请号：US11890256
申请日：2007-08-03
申请人： Raju R. Viswanathan
发明人： Raju R. Viswanathan
IPC分类号： G01R33/36
CPC分类号： G01R33/34061 , B82Y10/00 , B82Y25/00 , G01R33/34053 , G01R33/3415 , G01R33/3808
摘要： A method and apparatus for Magnetic Resonance Imaging with specialized imaging coils possessing high Signal-to-Noise-Ratio (SNR). Imaging and/or Radio Frequency receiving coils include a ballistic electrical conductor such as carbon nanotubes, the ballistic electrical conductor having a resistance that does not increase significantly with length. Due to their enhanced SNR properties, system designs with smaller static magnetic field strength can be constructed for the same quality of imaging, leading to substantial reductions in system size and cost, as well as to enhanced imaging with existing MRI systems.

46. 发明授权

US06560475B1 Microcoil device for local wide field-of-view and large gain magnetic resonance imaging 失效
标题翻译：用于局部宽视场和大增益磁共振成像的微线圈设备
公开(公告)号：US06560475B1
公开(公告)日：2003-05-06
申请号：US09532667
申请日：2000-03-21
申请人： Raju R. Viswanathan
发明人： Raju R. Viswanathan
IPC分类号： A61B505
CPC分类号： A61B5/055 , A61B5/4839 , A61B2090/3954 , A61M25/0043 , A61M25/0105 , A61M25/0108 , A61M25/0127 , G01R33/285
摘要： Microcoil designs are provided that enable unique RF response Field profiles that are particularly useful in MRI imaging procedures, particularly where fields of view outside of the medical device are desirable. These devices are particulatly for use within an organism, the device comprising an element having at least one RF receiver, the coils of said microcoils defining a cross-section that lies in a plane oriented at 0 to 90 (or 0 to 80) degrees to the longest axis of the device. Another way of describing the device is as a device for use in an organism, the device comprising an element having at least one wound microcoil with at least three windings on the microcoil. Each winding has an aspect ratio of greater than one. The aspect ratio of each winding is measured as the ratio of longest to shortest dimension in a cross section situated approximately transverse to the winding axis of the coil windings, the winding axis also being transverse to the longest axis of said device. Another way of describing the device for use within an organism is as a device comprising an element having at least one RF receiver microcoil, the coils of the microcoils defining a cross-sectional contour having an alignment value of at least 0.75 with the longest axis of the device. The coil windings of the microcoil may have the cross-section comprise a geometric shape, such as a curvilinear shape, a polygon (regular or irregular), or a polygon where comers on the polygon are softened (e.g., slighly rounded). The device may comprise a catheter having at least one lumen. At least one microcoil should be located with its longest dimension defining a longitudinal spatial extent (direction) parallel to the at least one lumen and the coils having a conductor thickness of greater than 0.01 mm and less than 2.4 mm.
摘要翻译：提供微线圈设计，其实现独特的RF响应在MRI成像过程中特别有用的场概况，特别是在需要医疗设备外的视场时。这些装置特别地用于生物体内，该装置包括具有至少一个RF接收器的元件，所述微线圈的线圈限定了一个横截面，该横截面位于朝向0至90（或0至80）度至设备的最长轴。描述装置的另一种方式是用作生物体的装置，该装置包括具有至少一个在微线圈上具有至少三个绕组的缠绕微线圈的元件。每个绕组的纵横比大于1。每个绕组的纵横比以与线圈绕组绕组轴线近似横截面的横截面中的最长与最短尺寸之比测量，卷绕轴线也横向于所述装置的最长轴线。描述在生物体内使用的装置的另一种方式是作为包括具有至少一个RF接收器微线圈的元件的装置，微线圈的线圈限定具有至少0.75的对准值的横截面轮廓，其中最长轴装置。微线圈的线圈绕组可以具有包括几何形状，例如曲线形状，多边形（规则的或不规则的）或多边形上的多边形的多边形的多边形的横截面（例如，细长的圆形）。该装置可以包括具有至少一个内腔的导管。至少一个微线圈应该被定位，其最长尺寸限定平行于至少一个内腔的纵向空间范围（方向），并且具有大于0.01mm且小于2.4mm的导体厚度的线圈。

47. 发明授权

US08196590B2 Variable magnetic moment MR navigation 失效
标题翻译：可变磁矩MR导航
公开(公告)号：US08196590B2
公开(公告)日：2012-06-12
申请号：US12145419
申请日：2008-06-24
申请人： Michael E. Sabo , Rogers C. Ritter , Roger N. Hastings , Raju R. Viswanathan
发明人： Michael E. Sabo , Rogers C. Ritter , Roger N. Hastings , Raju R. Viswanathan
IPC分类号： A61B19/00 , A61M35/00
CPC分类号： A61B5/055 , A61B5/06
摘要： A method of navigating a medical device in an operating region in a subject. The method includes applying a magnetic field to the operating region and changing the magnetic moment of the medical device by selectively changing a physical condition of at least one magnet element in the medical device to change the orientation of the device with respect to the applied magnetic field.
摘要翻译：一种在受试者的操作区域中导航医疗装置的方法。该方法包括通过选择性地改变医疗装置中的至少一个磁体元件的物理状态来改变医疗装置的磁矩并改变相对于所施加的磁场的装置的取向来改变操作区域的磁场。

48. 发明授权

US08192374B2 Estimation of contact force by a medical device 有权
标题翻译：由医疗设备估计接触力
公开(公告)号：US08192374B2
公开(公告)日：2012-06-05
申请号：US11484884
申请日：2006-07-11
申请人： Raju R. Viswanathan
发明人： Raju R. Viswanathan
IPC分类号： A61B5/103 , A61B5/117 , A61B5/05 , A61B17/00 , A61B18/04
CPC分类号： A61B18/04 , A61B34/20 , A61B34/73 , A61B2034/102 , A61B2034/2051 , A61B2090/064 , A61B2090/065
摘要： A method is provided for establishing contact of a medical device against a tissue surface within a subject body, the method comprising determination of the geometrical configuration of the distal portion of the medical device, and using this together with known control variable information to determine and control the contact force of the distal tip of the medical device against the tissue surface.
摘要翻译：提供了一种用于建立医疗装置与受试者身体内的组织表面的接触的方法，所述方法包括确定医疗装置的远端部分的几何构型，并将其与已知的控制变量信息一起确定和控制医疗装置的远端顶端对组织表面的接触力。

49. 发明申请

US20110033100A1 REGISTRATION OF THREE-DIMENSIONAL IMAGE DATA TO 2D-IMAGE-DERIVED DATA 失效
标题翻译：将三维图像数据注册到2D图像衍生数据
公开(公告)号：US20110033100A1
公开(公告)日：2011-02-10
申请号：US12835211
申请日：2010-07-13
申请人： Raju R. Viswanathan
发明人： Raju R. Viswanathan
IPC分类号： G06K9/00
CPC分类号： G06K9/00208 , G06T7/33 , G06T7/38 , G06T2207/10072 , G06T2207/10121 , G06T2207/30048 , G06T2207/30101
摘要： A method for obtaining registration of a three-dimensional image data set of an anatomical vessel with corresponding two-dimensional image data of the vessel in an X-ray imaging system, where the method comprise the user identifying two points on an anatomical vessel on at least two X-ray image planes, the user identifying two similar points on the surface of the corresponding three-dimensional anatomical image data, determining the orientation direction of the vessel from the two user identified image data surface points, determining the orientation direction of the vessel from the two points obtained from the X-ray image planes, and calculating a transformation of the three-dimensional image data to obtain a best fit registration of the direction derived from the image surface points with the direction derived from the X-ray image data points.
摘要翻译：一种用于在X射线成像系统中获得具有血管的相应二维图像数据的解剖血管的三维图像数据集的注册的方法，其中所述方法包括用户识别解剖血管上的两个点至少两个X射线图像平面，用户识别相应三维解剖图像数据的表面上的两个相似点，从两个用户识别的图像数据表面点确定血管的取向方向，确定血管的取向方向从X射线图像平面获得的两点获取血管，并计算三维图像数据的变换，以获得从图像表面点导出的方向与从X射线图像导出的方向的最佳拟合配准数据点。

50. 发明申请

US20110022029A1 CONTACT OVER-TORQUE WITH THREE-DIMENSIONAL ANATOMICAL DATA 有权
标题翻译：联系超扭矩与三维解剖数据
公开(公告)号：US20110022029A1
公开(公告)日：2011-01-27
申请号：US12830708
申请日：2010-07-06
申请人： Raju R. Viswanathan
发明人： Raju R. Viswanathan
IPC分类号： A61M25/00
CPC分类号： A61B1/00158 , A61B5/042 , A61B5/06 , A61B5/1076 , A61B5/6885 , A61B34/73
摘要： A method is provided for establishing contact of a medical device against a three-dimensional surface geometry within a subject body, the method comprising obtaining a three-dimensional tissue surface geometry of an anatomical region within the subject body, obtaining a target location on the surface for the device to contact, determining local surface geometry information in a neighborhood of the target location, and using this information to determine a change of at least one control variable for effecting an over-torque of the medical device to enhance contact of the device with the target surface.
摘要翻译：提供了一种用于建立医疗装置与受试者体内的三维表面几何形状的接触的方法，所述方法包括获得所述对象体内的解剖区域的三维组织表面几何形状，获得所述表面上的目标位置用于使所述设备接触，确定所述目标位置附近的局部表面几何信息，以及使用所述信息来确定至少一个控制变量的变化，以实现所述医疗设备的过扭矩以增强所述设备与目标表面。

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