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41. 发明申请

US20050065397A1 Endoluminal tool deployment system 有权
公开(公告)号：US20050065397A1
公开(公告)日：2005-03-24
申请号：US10991118
申请日：2004-11-16
申请人： Vahid Saadat , Richard Ewers , Eugene Chen , David Miller
发明人： Vahid Saadat , Richard Ewers , Eugene Chen , David Miller
IPC分类号： A61B1/005 , A61B1/018 , A61B1/313 , A61B17/34 , A61B1/00
CPC分类号： A61B17/00234 , A61B1/0055 , A61B1/0057 , A61B1/018 , A61B1/313 , A61B2017/003 , A61B2017/00323 , A61B2017/00349 , A61B2017/2906 , A61B2017/3445 , A61B2090/306 , A61B2090/508 , A61M25/0043 , A61M25/0105 , A61M25/0147 , A61M2025/0096
摘要： Systems, devices and methods are provided for endoscopic procedures involving tissue manipulations beyond the capabilities of traditional endoscopic instruments. Embodiments of the systems include an elongated main body having a scope therethrough and at least one steerable tool arm which extends from the distal end of the main body. In preferred embodiments, the system includes two tool arms, each arm steerable to form a curve laterally outward which then bends laterally inward so that the arms form an angular shape. In addition, end effectors extend from the distal ends of each tool arm for use in manipulation of tissue. The angular shape brings the end effectors together in view of the scope for cooperative movements which are continuously visible by the surgeon. In addition, the tool arms may be steerable in any additional direction and may be rotateable to allow grasping, elevation and more complex manipulation of tissue.

42. 发明授权

US6057689A Apparatus and method for leak detection in a fluid-filled balloon useful to treat body tissue 失效
标题翻译：用于治疗身体组织的流体填充球囊中的泄漏检测装置和方法
公开(公告)号：US6057689A
公开(公告)日：2000-05-02
申请号：US905367
申请日：1997-08-04
申请人： Vahid Saadat
发明人： Vahid Saadat
IPC分类号： A61M25/00 , A61F2/958 , G01M3/18 , G01R31/12 , G01N27/00
CPC分类号： G01M3/187
摘要： An apparatus for detecting leaks in a fluid-filled device used to treat a patient's tissue includes an catheter having an expandable device defining a fluid reservoir about the distal end of the catheter. An internal electrode is in electrical contact with a conductive fluid within the fluid reservoir. A grounding electrode is outside of the fluid reservoir, in electrical contact with the patient's tissue. Voltage is supplied to the internal electrode and the grounding electrode. Where a leak occurs in the expandable device, conductive fluid will contact the patient's tissue, thus creating an electrical current path between the internal electrode and the grounding electrode. This so-called "leak current" is used to generate a leak alarm signal.
摘要翻译：用于检测用于治疗患者组织的流体填充装置中的泄漏的装置包括具有可扩张装置的导管，该可扩张装置围绕导管的远端界定流体储存器。内部电极与流体储存器内的导电流体电接触。接地电极位于流体储存器的外部，与患者的组织电接触。电压被提供给内部电极和接地电极。在可扩张装置中发生泄漏的情况下，导电流体将接触病人的组织，从而在内部电极和接地电极之间产生电流通路。这种所谓的“泄漏电流”用于产生泄漏报警信号。

43. 发明授权

US5972012A Cutting apparatus having articulable tip 失效
标题翻译：切割装置具有铰接尖端
公开(公告)号：US5972012A
公开(公告)日：1999-10-26
申请号：US27828
申请日：1998-02-19
申请人： John H. Ream , Vahid Saadat
发明人： John H. Ream , Vahid Saadat
IPC分类号： A61B17/00 , A61B17/22 , A61B17/28 , A61B17/30 , A61B17/32 , A61B17/34 , A61B18/14 , A61B19/00
CPC分类号： A61B17/32002 , A61B17/3207 , A61B17/320758 , A61B18/148 , A61B17/3478 , A61B18/1492 , A61B2017/00022 , A61B2017/00026 , A61B2017/00247 , A61B2017/003 , A61B2017/00398 , A61B2017/00685 , A61B2017/00703 , A61B2017/22077 , A61B2017/2927 , A61B2017/308 , A61B2017/320028 , A61B2017/320084 , A61B2017/3445 , A61B2017/3488 , A61B2018/00196 , A61B2018/00208 , A61B2018/00267 , A61B2018/00279 , A61B2018/00291 , A61B2018/00392 , A61B2018/00738 , A61B2018/00761 , A61B2018/00839 , A61B2018/00916 , A61B2018/124 , A61B2018/1435 , A61B2018/1437 , A61B2018/1861 , A61B2090/064 , A61B2090/3782 , A61B2090/3784 , A61B2218/002 , A61B2218/007 , A61B34/20 , A61B90/37
摘要： Apparatus and methods for intraoperatively performing surgery to create transmural channels in tissue, for example, as in transmyocardial revascularization, are provided using apparatus having an end region containing a mechanical cutting head and means for articulating the end-region to access hard-to-reach portions of the anatomy. The handpiece is coupled by a disposable cable to a controller that houses a vacuum pump and mechanisms for driving the cutting head. The cutting head is adapted to cooperate with the vacuum pump to evacuate tissue severed during the channel forming process.
摘要翻译：用于在手术中进行手术以在组织中产生透壁通道的装置和方法，例如在心肌血运重建中，使用具有包含机械切割头的端部区域的装置和用于铰接末端区域以访问难以到达的装置部分解剖结构。手持件通过一次性电缆连接到容纳真空泵的控制器和用于驱动切割头的机构。切割头适于与真空泵配合以排出在通道形成过程中切断的组织。

44. 发明授权

US5954714A Heated balloon having rotary fluid impeller 失效
标题翻译：加热气球具有旋转流体叶轮
公开(公告)号：US5954714A
公开(公告)日：1999-09-21
申请号：US752501
申请日：1996-11-20
申请人： Vahid Saadat , John J. McIntyre , Gail Stevens
发明人： Vahid Saadat , John J. McIntyre , Gail Stevens
IPC分类号： A61B17/42 , A61B17/00 , A61B18/00 , A61B18/04 , A61B18/08 , A61F7/12 , A61M25/00 , A61B17/38
CPC分类号： A61F7/123 , A61B18/08 , A61B18/00 , A61B2017/00557 , A61B2017/4216 , A61B2018/00559
摘要： Apparatus for thermal coagulation having an improved circulation assembly and heating assembly. The apparatus includes a balloon catheter secured to and in fluid communication with a handle for inserting the apparatus into a human uterus. A distensible bladder is secured to the distal end of the catheter and encloses a heating assembly having a tubular core configured with a spiral groove which retains a heating filament. An impeller having at least two blades is positioned distal of the heating assembly and includes a cable having a distal end secured to the impeller. The impeller cable is partially disposed in the handle, in the elongate tubular member and in the core of the heating element, such that axial rotation of said cable rotates the blades of said impeller. During use of the apparatus, the distensible bladder is inflated with a fluid to a desired pressure and rotation of the impeller blades is initiated. The inflation fluid within the distensible bladder is heated to a desired temperature, which is maintained for a desired time interval. The inflation fluid within the distensible bladder is allowed to cool and rotation of the impeller blades is terminated. Thereafter, the inflation fluid is removed from the balloon catheter to deflate the distensible bladder.
摘要翻译：具有改进的循环组件和加热组件的热凝固装置。该装置包括固定在手柄上且与手柄流体连通的气囊导管，用于将装置插入人子宫。可扩张的囊被固定到导管的远端，并且包围一个加热组件，该加热组件具有一个管状芯体，其配置有一个保持加热细丝的螺旋槽。具有至少两个叶片的叶轮位于加热组件的远侧，并且包括具有固定到叶轮的远端的电缆。叶轮电缆部分地设置在手柄中，在细长管状构件中和加热元件的芯部中，使得所述电缆的轴向旋转使所述叶轮的叶片旋转。在使用该装置的过程中，可膨胀囊被流体充气至期望的压力，并且叶轮叶片的旋转开始。可膨胀膀胱内的充气流体被加热到期望的温度，其保持期望的时间间隔。允许扩张囊内的充气流体冷却并终止叶轮的旋转。此后，将膨胀流体从球囊导管中移出以使可膨胀囊膨胀。

45. 发明授权

US5899915A Apparatus and method for intraoperatively performing surgery 失效
标题翻译：术中手术手术及方法
公开(公告)号：US5899915A
公开(公告)日：1999-05-04
申请号：US953046
申请日：1997-10-17
申请人： Vahid Saadat
发明人： Vahid Saadat
IPC分类号： A61B17/32 , A61B17/00 , A61B17/22 , A61B17/28 , A61B17/30 , A61B17/34 , A61B18/14 , A61B19/00
CPC分类号： A61B17/32002 , A61B17/3207 , A61B17/320758 , A61B18/148 , A61B17/3478 , A61B18/1492 , A61B2017/00022 , A61B2017/00026 , A61B2017/00247 , A61B2017/003 , A61B2017/00398 , A61B2017/00685 , A61B2017/00703 , A61B2017/22077 , A61B2017/2927 , A61B2017/308 , A61B2017/320084 , A61B2017/3445 , A61B2017/3488 , A61B2018/00196 , A61B2018/00208 , A61B2018/00267 , A61B2018/00279 , A61B2018/00291 , A61B2018/00392 , A61B2018/00738 , A61B2018/00761 , A61B2018/00839 , A61B2018/00916 , A61B2018/124 , A61B2018/1435 , A61B2018/1437 , A61B2018/1861 , A61B2090/064 , A61B2090/3782 , A61B2090/3784 , A61B2218/002 , A61B2218/007 , A61B34/20 , A61B90/37
摘要： Apparatus and methods for intraoperatively performing surgery to create transmural channels in tissue, for example, as in transmyocardial revascularization, are provided using a device including a mechanical end effector and means for stabilizing the end effector in contact with the tissue. The end effector is adapted to cooperate with a source of suction to evacuate tissue severed during the channel forming process, and may optionally include an electrode for cauterizing the tissue surrounding the channel.
摘要翻译：使用包括机械末端执行器的装置和用于稳定与组织接触的末端执行器的装置来提供用于在手术中进行手术以在组织中产生透壁通道的装置和方法，例如在心肌血运重建中。端部执行器适于与吸入源协作以排出在通道形成过程期间切断的组织，并且可任选地包括用于烧灼围绕通道的组织的电极。

46. 发明授权

US10335131B2 Methods for preventing tissue migration 有权
公开(公告)号：US10335131B2
公开(公告)日：2019-07-02
申请号：US11877386
申请日：2007-10-23
申请人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam , Chris A. Rothe
发明人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam , Chris A. Rothe
IPC分类号： A61B1/00 , A61B17/02 , A61B1/313 , A61B17/34 , A61B1/005 , A61B6/00 , A61B8/08
摘要： A method of inhibiting tissue migration comprises positioning an open area of a hood against or adjacent to a tissue region. The method also comprises displacing an opaque fluid with a transparent fluid from the open area. The method includes engaging a portion of the tissue region within the open area via an end effector advanced through the open area and which grasps onto the portion. The end effector includes a tapered section, tapered along its entire length, through which a lumen extends. The tapered section includes threads extending from a surface of the tapered section in a direction orthogonal to the longitudinal axis. The tissue region is pierced while displacing the opaque fluid with the transparent fluid through the distal opening of the hood and while maintaining engagement of the portion of the tissue region such that distal movement of the tissue is inhibited.

47. 发明授权

US09814522B2 Apparatus and methods for ablation efficacy 有权
公开(公告)号：US09814522B2
公开(公告)日：2017-11-14
申请号：US13081363
申请日：2011-04-06
申请人： Michael J. Drews , Bryan Wylie , Leslie Oley , Vahid Saadat
发明人： Michael J. Drews , Bryan Wylie , Leslie Oley , Vahid Saadat
IPC分类号： A61B18/14 , A61B18/00 , A61B18/08 , A61B90/00
CPC分类号： A61B18/1492 , A61B18/082 , A61B2018/00273 , A61B2018/00351 , A61B2018/00375 , A61B2018/0038 , A61B2018/00577 , A61B2018/00982 , A61B2018/1472 , A61B2018/1475 , A61B2090/0436 , A61B2090/0481 , A61B2218/002
摘要： Apparatus and methods for ablation efficacy are described herein where a hood having a deployable elongated feature can extend beyond a distal face of the hood. The elongated feature can channel the energy to the deeper regions within the tissue (such as trabeculated regions or other tissue structures) such that the energy can be delivered to the target tissue despite small or large irregularities in the target tissue surface (or region) and/or changes in the relative distances between the hood and the target tissue.

48. 发明申请

US20160227989A1 Delivery Of Biological Compounds To Ischemic And/Or Infarcted Tissue 审中-公开
标题翻译：向缺血和/或梗塞组织递送生物化合物
公开(公告)号：US20160227989A1
公开(公告)日：2016-08-11
申请号：US15130416
申请日：2016-04-15
申请人： Vahid Saadat , Sekhar S. Rao
发明人： Vahid Saadat , Sekhar S. Rao
IPC分类号： A61B1/00 , A61B1/015 , A61B1/05 , A61B5/00
CPC分类号： A61B1/00165 , A61B1/00089 , A61B1/00096 , A61B1/00147 , A61B1/015 , A61B1/05 , A61B1/12 , A61B5/0084 , A61B5/6882 , A61B5/7282 , A61M25/0074 , A61M25/0082 , A61M25/0084
摘要： The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue.
摘要翻译：在本文中描述了将生物化合物递送至缺血和/或梗死组织，其中这样的系统可以包括展开导管和可展开成扩展构型的附接成像罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。此外，任何数量的治疗工具也可以通过展开导管并进入成像罩，以在组织上执行任何数量的程序，用于识别，定位和/或获取缺血和/或梗死组织。

49. 发明授权

US09247952B2 Devices and methods for tissue access 有权
标题翻译：用于组织进入的装置和方法
公开(公告)号：US09247952B2
公开(公告)日：2016-02-02
申请号：US12984162
申请日：2011-01-04
申请人： Jeffery L. Bleich , Edwin J. Hlavka , Vahid Saadat , David J. Miller , James R. Yurchenco
发明人： Jeffery L. Bleich , Edwin J. Hlavka , Vahid Saadat , David J. Miller , James R. Yurchenco
IPC分类号： A61B17/00 , A61B17/32 , A61B17/16 , A61B17/29 , A61B17/3205 , A61B17/3207 , A61B17/34 , A61B19/00 , A61F2/00 , A61B5/00 , A61B17/295 , A61B18/02 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/20 , A61B17/14 , A61B18/00 , A61N1/36 , A61N7/02
CPC分类号： A61B17/320016 , A61B5/4893 , A61B17/149 , A61B17/1671 , A61B17/29 , A61B17/295 , A61B17/32002 , A61B17/32053 , A61B17/320758 , A61B17/3401 , A61B17/3403 , A61B17/3421 , A61B17/3496 , A61B18/02 , A61B18/082 , A61B18/1477 , A61B18/1487 , A61B18/1815 , A61B18/20 , A61B90/04 , A61B2017/00261 , A61B2017/00287 , A61B2017/003 , A61B2017/00867 , A61B2017/320004 , A61B2017/320044 , A61B2017/32006 , A61B2017/3445 , A61B2017/3447 , A61B2018/00577 , A61B2018/00595 , A61B2018/1407 , A61B2018/1425 , A61B2034/2063 , A61B2090/061 , A61B2090/08021 , A61B2090/374 , A61B2090/376 , A61B2090/3762 , A61F2/0045 , A61N1/36017 , A61N7/02
摘要： Methods and apparatus are provided for selective surgical removal of tissue, e.g., for enlargement of diseased spinal structures, such as impinged lateral recesses and pathologically narrowed neural foramen. In some embodiments, a surgical tissue removal device includes a flexible elongate body that is adapted to conform with the target anatomy and a guidewire connector at the distal end region of the flexible elongate body configured to removably connect to the end of a guidewire so that the guidewire and flexible elongate body can be pulled distally. The body may have at least one blade edge, and the flexible elongate body may be a thin, flat, ribbon shaped flexible body that includes a profile having a width that is substantially greater than a height.
摘要翻译：提供了用于选择性手术去除组织的方法和装置，例如用于扩大患病的脊柱结构，例如冲击的侧向凹陷和病理变窄的神经孔。在一些实施例中，手术组织去除装置包括适于与目标解剖结构一致的柔性细长主体和在柔性细长主体的远端区域处的导丝连接器，其构造成可移除地连接到导丝的端部，使得导丝和柔性细长体可以向远侧拉。主体可以具有至少一个叶片边缘，并且柔性细长主体可以是薄的，扁平的带状柔性主体，其包括具有基本上大于高度的宽度的轮廓。

50. 发明授权

US09192287B2 Tissue visualization device and method variations 有权
标题翻译：组织可视化装置和方法的变化
公开(公告)号：US09192287B2
公开(公告)日：2015-11-24
申请号：US13526254
申请日：2012-06-18
申请人： Vahid Saadat , Chris A. Rothe , Edmund Tam , Ruey-Feng Peh
发明人： Vahid Saadat , Chris A. Rothe , Edmund Tam , Ruey-Feng Peh
IPC分类号： A61B1/00 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/02 , A61B5/00 , A61B17/00 , A61B17/04 , A61B8/12 , A61B17/22 , A61B18/24
CPC分类号： A61B1/00085 , A61B1/0008 , A61B1/00082 , A61B1/00089 , A61B1/00091 , A61B1/00177 , A61B1/005 , A61B1/012 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/02007 , A61B5/6882 , A61B8/12 , A61B17/00234 , A61B17/0057 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/22012 , A61B18/24 , A61B2017/048 , A61B2017/0496
摘要： Tissue visualization devices and variations thereof are described herein where such devices may utilize a variety of methods for facilitating clearing of the device of opaque bodily fluids and sealing between the device and the underlying tissue surface. Additionally, methods and devices for enhancing navigation of the device through a patient body are also described.
摘要翻译：本文描述了组织可视化装置及其变型，其中这样的装置可以利用各种方法来促进不透明体液的装置的清除和装置与下面的组织表面之间的密封。此外，还描述了用于增强穿过患者身体的装置导航的方法和装置。

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