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41. 发明授权

US07049583B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US07049583B2
公开(公告)日：2006-05-23
申请号：US10636753
申请日：2003-08-08
申请人： Robert Harold Bateman , Jeff Brown
发明人： Robert Harold Bateman , Jeff Brown
IPC分类号： H01J49/04
CPC分类号： H01J49/0418 , H01J49/424
摘要： A mass spectrometer is disclosed comprising an ion trap ion source wherein a microtitre sample or target plate forms part of one end-cap electrode.
摘要翻译：公开了一种质谱仪，其包括离子阱离子源，其中微量滴定样品或靶板形成一个端帽电极的一部分。

42. 外观设计

USD516217S1 Handheld biomedical monitoring device 失效
标题翻译：手持式生物医学监测装置
公开(公告)号：USD516217S1
公开(公告)日：2006-02-28
申请号：US29203950
申请日：2004-04-21
申请人： Jeff Brown , Michael Heare
设计人： Jeff Brown , Michael Heare

43. 发明授权

US06906318B2 Ion detector 有权
标题翻译：离子检测器
公开(公告)号：US06906318B2
公开(公告)日：2005-06-14
申请号：US10777574
申请日：2004-02-12
申请人： Robert Harold Bateman , Jeff Brown , Martin Green
发明人： Robert Harold Bateman , Jeff Brown , Martin Green
IPC分类号： B01D59/44 , G01K1/08 , H01J37/244 , H01J49/00 , H01J49/40
CPC分类号： H01J43/246
摘要： An ion detector 7 for a mass spectrometer is disclosed comprising a microchannel plate 8 which receives ions 12 at an input surface and releases secondary electrons 16 from an output surface. A detecting device 9 having a detecting surface is arranged to receive at least some of the electrons 16 emitted by the microchannel plate 8. The area of the detecting surface is substantially greater than the area of the output surface of the microchannel plate 8.
摘要翻译：公开了一种用于质谱仪的离子检测器7，其包括微通道板8，微通道板8在输入表面处接收离子12并从输出表面释放二次电子16。具有检测表面的检测装置9布置成接收由微通道板8发射的至少一些电子16。检测表面的面积显着大于微通道板8的输出表面的面积。

44. 发明授权

US06875980B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US06875980B2
公开(公告)日：2005-04-05
申请号：US10636767
申请日：2003-08-08
申请人： Robert Harold Bateman , Jeff Brown
发明人： Robert Harold Bateman , Jeff Brown
IPC分类号： H01J49/34 , H01J49/40 , H01J49/42
CPC分类号： H01J49/004 , H01J49/42
摘要： A mass spectrometer is disclosed wherein a relatively energetic pulse of ions having a relatively narrow spread of mass to charge ratios are ejected from a quadrupole ion trap and received in an ion trap upstream of a Time of Flight mass analyser. The ions are collisionally cooled within the ion trap and are pulsed out of the ion trap and into an extraction region of the Time of Flight mass analyser without substantially exciting the ions. This enables improved operation with the Time of Flight mass analyser. According to another embodiment, parent ions are fragmented and the resulting fragment ions are stored in two ion traps having different low mass cut-offs. The trapping system enables MS/MS experiments to be performed with a very high duty cycle.
摘要翻译：公开了一种质谱仪，其中具有相对较窄的质荷比扩散的相对高能的离子脉冲从四极离子阱排出并被接收在飞行时间质量分析器上游的离子阱中。离子在离子阱内被碰撞冷却，并从离子阱中脉冲出并进入飞行时间质量分析仪的提取区域，而基本上不激励离子。这可以通过“飞行时间”质量分析仪进行改进的操作。根据另一个实施方案，母体离子是碎片化的，所得到的碎片离子存储在具有不同低质量截止值的两个离子阱中。捕获系统能够以非常高的占空比执行MS / MS实验。

45. 发明申请

US20050023453A1 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US20050023453A1
公开(公告)日：2005-02-03
申请号：US10633702
申请日：2003-08-05
申请人： Robert Bateman , Kevin Giles , John Hoyes , Steve Pringle , Jeff Brown
发明人： Robert Bateman , Kevin Giles , John Hoyes , Steve Pringle , Jeff Brown
IPC分类号： H01J49/00 , H01J49/42
CPC分类号： H01J49/4225
摘要： A mass spectrometer is disclosed comprising an ion trap wherein ions which have been temporally separated according to their mass to charge ratio or ion mobility enter the ion trap. Once at least some of the ions have entered the ion trap, a plurality of ion trapping regions are created along the length of the ion trap in order to fractionate the ions. Alternatively, the ions may be received within one or more axial trapping regions which are translated along the ion trap with a velocity which is progressively reduced to zero.
摘要翻译：公开了一种质谱仪，其包括离子阱，其中根据其质荷比或离子迁移率暂时分离的离子进入离子阱。一旦至少一些离子已经进入离子阱，沿着离子阱的长度产生多个离子捕获区域，以分离离子。或者，离子可以被接收在一个或多个沿着离子阱平移的轴向捕获区域中，其速度逐渐减小到零。

46. 发明授权

US06794640B2 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US06794640B2
公开(公告)日：2004-09-21
申请号：US10301710
申请日：2002-11-22
申请人： Robert Harold Bateman , Jeff Brown , Anthony James Gilbert
发明人： Robert Harold Bateman , Jeff Brown , Anthony James Gilbert
IPC分类号： H01J4900
CPC分类号： H01J49/004 , H01J49/401 , H01J49/42
摘要： A mass spectrometer is disclosed comprising a mass selective ion trap such as a 3D quadrupole field ion trap upstream of a pusher electrode of an orthogonal acceleration Time of Flight mass analyzer. According to a first embodiment bunches of ions are released from the ion trap and the pusher electrode is energised after a delay time which is progressively varied. According to a second embodiment ions are released from the ion trap in reverse order of mass to charge ratio with the ions having the largest mass to charge ratio being released first. By appropriate release of the ions from the ion trap it is possible to ensure that substantially all of the ions arrive at the pusher electrode at substantially the same time. According to both embodiments it is possible to achieve a duty cycle approaching 100% across a large range of mass to charge ratios.
摘要翻译：公开了一种质谱仪，其包括质量选择性离子阱，例如正交加速时间飞行质量分析仪的推进器电极上游的3D四极场离子阱。根据第一实施例，一束离子从离子阱中释放出来，并且推进器电极在逐渐变化的延迟时间之后通电。根据第二实施方案，离子从离子阱以与质荷比最大的离子的质荷比相反的顺序被释放。通过从离子阱适当释放离子，可以确保基本上所有的离子基本上同时到达推动器电极。根据两个实施例，可以实现在大范围的质荷比之间接近100％的占空比。

47. 发明授权

US06243760B1 Information dissemination system with central and distributed caches 失效
标题翻译：具有中央和分布式缓存的信息传播系统
公开(公告)号：US06243760B1
公开(公告)日：2001-06-05
申请号：US08881113
申请日：1997-06-24
申请人： Brian Armbruster , Peter Wall , Jeff Brown
发明人： Brian Armbruster , Peter Wall , Jeff Brown
IPC分类号： G06F1338
CPC分类号： G06F17/3089 , G06F17/30902 , H04L67/28 , H04L67/2842 , H04L67/2885 , H04L67/42 , H04L69/16 , H04L69/329
摘要： A system for disseminating information over a wide area network includes a central caching unit for storing data to be made available over the wide area network. Local access give users access to the wide area network. Distributed caching units associated with the local access nodes for store cacheable material. A satellite communications system establishes satellite communications between the central caching unit and the local caching units for the transfer of cacheable material from the central caching unit to the local units. A router at the local access nodes routes packets from users to a destination address. The router includes local routing tables containing the addresses of material cached at the associated local node and responds to routing requests for locally cached material by directing the requests to the local cache.
摘要翻译：用于通过广域网传播信息的系统包括用于存储要在广域网上可用的数据的中央缓存单元。本地访问使用户可以访问广域网。与本地访问节点相关联的分布式缓存单元用于存储可缓存材料。卫星通信系统在中央缓存单元和本地高速缓存单元之间建立卫星通信，用于将可缓冲材料从中央缓存单元传送到本地单元。本地接入节点的路由器将数据包从用户路由到目的地址。路由器包括本地路由表，其中包含在关联的本地节点缓存的资料的地址，并通过将请求引导到本地缓存来响应本地缓存资源的路由请求。

48. 发明授权

US5221457A System for analyzing ion levels in fluids 失效
标题翻译：用于分析流体中离子水平的系统
公开(公告)号：US5221457A
公开(公告)日：1993-06-22
申请号：US763696
申请日：1991-09-23
申请人： John R. North , Robert L. Kay , Jeff Brown , Mark Eike , Neil Plotkin
发明人： John R. North , Robert L. Kay , Jeff Brown , Mark Eike , Neil Plotkin
IPC分类号： G01N33/487
CPC分类号： G01N33/48785
摘要： A system for analyzing the ion level of a fluid sample including an analyzer instrument, containing electrical circuitry for analyzing the ion level of the fluid sample, in electrical communication with a sensor unit having an ion selective electrode in communication with the fluid sample and electrical contacts for communication with the analyzer instrument. A recharger unit for the analyzer instrument is also disclosed.
摘要翻译：一种用于分析流体样品的离子水平的系统，包括分析仪器，其包含用于分析流体样品的离子水平的电路，与具有与流体样品和电触点连通的离子选择性电极的传感器单元电连通用于与分析仪器通讯。还公开了一种用于分析仪器的充电器单元。

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