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41. 发明授权

US08353851B2 Apparatus for automatic replacement of instruments during minimally invasive procedures 有权
标题翻译：用于在微创手术期间自动更换仪器的装置
公开(公告)号：US08353851B2
公开(公告)日：2013-01-15
申请号：US11453611
申请日：2006-06-15
申请人： Jan Boese , Reinmar Killmann
发明人： Jan Boese , Reinmar Killmann
IPC分类号： A61B5/103 , A61B5/117
CPC分类号： A61B90/10 , A61B34/73 , A61B90/00 , A61B2017/00243 , A61B2017/00362 , A61B2017/3445
摘要： The invention relates to an apparatus for automatic replacement of instruments during minimally invasive procedures, comprising a housing, an outlet element for an instrument, a selection unit and a guide element.
摘要翻译：本发明涉及一种在微创手术过程中自动更换仪器的装置，包括一个外壳，一个仪器出口元件，一个选择单元和一个导向元件。

42. 发明申请

US20120307964A1 System for Medical Imaging Using Long Persistence Contrast Agents 有权
标题翻译：使用长寿命对比剂进行医学影像系统
公开(公告)号：US20120307964A1
公开(公告)日：2012-12-06
申请号：US13484311
申请日：2012-05-31
申请人： Andrew F. Hall , Jan Boese
发明人： Andrew F. Hall , Jan Boese
IPC分类号： A61B6/03
CPC分类号： A61B6/481 , A61B6/03 , A61B6/503 , A61B6/504 , A61B6/541
摘要： A system acquires images in the presence of a contrast agent of relatively long persistence using a synchronization processor, image acquisition device and imaging controller. The synchronization processor provides an image acquisition trigger signal for acquiring images at a particular point within both a cardiac and a respiratory cycle in response to signals representing cardiac and respiratory cycles. The image acquisition device includes an assembly comprising a radiation emitter and detector rotatable about a patient for acquiring images of a portion of patient anatomy at different angles. The imaging controller initiates acquisition of data representing multiple images in the presence of a contrast agent of relatively long persistence by repetitively, initiating rotation of the assembly to an angle, acquiring an image at the angle in response to the trigger signal and incrementally increasing the angle.
摘要翻译：系统使用同步处理器，图像获取装置和成像控制器在存在具有较长持久性的造影剂的情况下获取图像。同步处理器响应于表示心脏和呼吸周期的信号，提供用于在心脏和呼吸周期内的特定点获取图像的图像采集触发信号。图像采集装置包括一个组件，该组件包括辐射发射器和围绕患者旋转的检测器，用于以不同的角度获取患者解剖结构的一部分的图像。成像控制器在存在持续时间相对较长的造影剂的情况下启动表示多个图像的数据，重复地启动组件的旋转角度，响应于触发信号以角度获取图像并递增地增加角度。

43. 发明授权

US08099155B2 Method for assisting with percutaneous interventions 有权
标题翻译：辅助经皮介入治疗的方法
公开(公告)号：US08099155B2
公开(公告)日：2012-01-17
申请号：US12229332
申请日：2008-08-21
申请人： Jan Boese , Estelle Camus , Matthias John
发明人： Jan Boese , Estelle Camus , Matthias John
IPC分类号： A61B5/00
CPC分类号： A61B8/00 , A61B6/4441 , A61B6/464 , A61B6/5247 , A61B8/0841 , A61B8/483 , A61B17/3403 , A61B90/37 , A61B2017/00694 , A61B2017/3413 , A61B2090/364 , A61B2090/365 , A61B2090/367 , A61B2090/376 , A61B2090/3762 , A61B2090/378 , G06T7/38 , G06T2207/10081 , G06T2207/10132 , G06T2207/20221 , G06T2207/30056
摘要： The present invention relates to a method for assisting with percutaneous interventions, wherein 2D x-ray images of an object region are recorded before the intervention using a C-arm x-ray system or a robot-based x-ray system at different projection angles and 3D x-ray image data of the object region is reconstructed from the 2D x-ray recordings. One or more 2D or 3D ultrasound images are recorded before and/or during the intervention using an external ultrasound system and registered with the 3D image data. The 2D or 3D ultrasound images are then overlaid with the 3D image data record or a target region segmented therefrom or displayed next to one another in the same perspective. The method allows a puncture or biopsy to be monitored with a low level of radiation.
摘要翻译：本发明涉及一种辅助经皮干预的方法，其中使用C臂x射线系统或以不同投影角度的基于机器人的x射线系统在介入前记录对象区域的2D x射线图像并且从2D X射线记录重建对象区域的3D X射线图像数据。使用外部超声系统在干预之前和/或期间记录一个或多个2D或3D超声图像，并且与3D图像数据一起登记。然后将2D或3D超声图像与3D图像数据记录或从其分割的目标区域或以相同的视角彼此相邻地显示。该方法允许以低水平的辐射监测穿刺或活检。

44. 发明授权

US08054941B2 Method for the production of angiography recordings 有权
标题翻译：生产血管造影记录的方法
公开(公告)号：US08054941B2
公开(公告)日：2011-11-08
申请号：US12507818
申请日：2009-07-23
申请人： Jan Boese , Yu Deuerling-Zheng , Michael Zellerhoff
发明人： Jan Boese , Yu Deuerling-Zheng , Michael Zellerhoff
IPC分类号： H05G1/64 , H05G1/60 , H05G1/58 , G01N23/083
CPC分类号： A61B6/504 , A61B5/055 , A61B6/4458 , A61B6/481 , A61B6/488 , A61B6/541
摘要： The invention relates to a method for the production of angiography recordings. First, a mask image is recorded with a first modality. A contrast medium is injected after the first recording. A control image is recorded with a second modality after the injection of the contrast medium. A spreading of the contrast medium is determined based on the images and the control of subsequent recordings is analyzed. A recording criterion is checked to determine whether the recording criterion has been achieved. If it has not been achieved, the control image is repeatedly recorded for repeatedly determining the spreading of the contrast medium. If it has been achieved, a contrast image is recorded with the first modality and the mask image and the contrast image are processed and analyzed.
摘要翻译：本发明涉及一种生产血管造影记录的方法。首先，以第一模式记录掩模图像。在第一次记录之后注射造影剂。在注射造影剂之后，以第二模态记录控制图像。基于图像确定造影剂的扩展，并分析后续记录的控制。检查记录标准以确定是否已经实现了记录标准。如果还没有实现，则重复记录控制图像以重复确定造影剂的扩展。如果已经实现，则用第一模态记录对比度图像，并且处理和分析掩模图像和对比度图像。

45. 发明申请

US20110268341A1 Method for Reconstruction of a Current Three-Dimensional Image Dataset of an Object During a Monitoring Process and X-Ray Device 有权
标题翻译：在监测过程和X射线设备期间重建对象的当前三维图像数据集的方法
公开(公告)号：US20110268341A1
公开(公告)日：2011-11-03
申请号：US13094423
申请日：2011-04-26
申请人： Jan Boese , Frank Dennerlein
发明人： Jan Boese , Frank Dennerlein
IPC分类号： G06K9/00 , G01N23/04 , B82Y99/00
CPC分类号： A61B6/4007 , A61B6/4021 , A61B6/5205 , A61B2090/3764 , G06T11/006 , G06T2211/412 , H01J35/065 , H01J2201/30469 , H01J2235/062 , H01J2235/068
摘要： A method for reconstruction of an actual three-dimensional image dataset of an object during a monitoring process is proposed. Two-dimensional. X-ray projection images which correspond to a recording geometry are continuously recorded from different projection angles. The three-dimensional image dataset are reconstructed from a first number of these projection images, especially by a back projection method. The proportion of the oldest projection image contained in the current three-dimensional image dataset is removed from the three-dimensional image dataset and the proportion of the actual projection image is inserted in the three-dimensional image dataset after each recording of the actual projection image.
摘要翻译：提出了一种用于在监视过程中重建对象的实际三维图像数据集的方法。二维。对应于记录几何的X射线投影图像从不同的投影角度连续记录。从第一数量的这些投影图像，特别是通过反投影方法重构三维图像数据集。将包含在当前三维图像数据集中的最旧的投影图像的比例从三维图像数据集中去除，并且在每次记录实际投影图像之后将实际投影图像的比例插入到三维图像数据集中。

46. 发明授权

US08045780B2 Device for merging a 2D radioscopy image with an image from a 3D image data record 有权
标题翻译：用于将2D放射成像图像与来自3D图像数据记录的图像合并的装置
公开(公告)号：US08045780B2
公开(公告)日：2011-10-25
申请号：US11904583
申请日：2007-09-27
申请人： Jan Boese , Matthias John , Norbert Rahn
发明人： Jan Boese , Matthias John , Norbert Rahn
IPC分类号： G06K9/00
CPC分类号： G06T15/08 , G06T7/38 , G06T11/008 , G06T2207/10072
摘要： The invention relates to a device for merging a 2D radioscopy image with an image obtained from a 3D image data record, having a memory unit that stores the 2D radioscopy image and the 3D image data record, a segmentation unit that segments an inner surface of a hollow organ from the 3D image data record, a registration unit that registers the 2D radioscopy image with the 3D image data record, a back-projection unit that back-projects the pixels of the 2D radioscopy image onto the segmented surface, taking account of the projection geometry of the 2D radioscopy image and the registration, and an image merger unit that generates a virtual endoscopy view of the surface from the segmented surface using the back-projected pixels. The device primarily allows 2D radioscopy images to be superimposed during interventional procedures with a fly display of the interior of an interesting organ.
摘要翻译：本发明涉及一种用于将2D放射线图像与从3D图像数据记录获得的图像合并的装置，具有存储2D放射线图像和3D图像数据记录的存储单元，分割单元，其将来自3D图像数据记录的空心器官，将2D放射线图像与3D图像数据记录注册的登记单元，将2D放射线图像的像素反投影到分割表面上的背投影单元，考虑到 2D放射线图像的投影几何图像和配准，以及图像合并单元，其使用后投影像素从分割表面生成表面的虚拟内窥镜视图。该装置主要允许在介入手术过程中叠加2D放射成像图像，并显示有趣器官内部的飞行显示。

47. 发明授权

US08023707B2 Evaluation method for mapping the myocardium of a patient 有权
标题翻译：用于绘制患者心肌的评估方法
公开(公告)号：US08023707B2
公开(公告)日：2011-09-20
申请号：US12079142
申请日：2008-03-25
申请人： Jan Boese , Yu Deuerling-Zheng
发明人： Jan Boese , Yu Deuerling-Zheng
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： A61B6/481 , A61B6/4441 , A61B6/503 , A61B6/504 , A61B6/507 , G06T5/50 , G06T7/0012 , G06T2207/10116 , G06T2207/30048
摘要： The invention relates to an evaluation method for mapping the myocardium of a patient, in particular the automated, functional evaluation, for instance the heart perfusion, in angiographic series with the steps: recording a series of angiographic recordings directly after administering a contrast agent to the patient; determining a reference area in an angiographic recording; determining a trend pattern of the contrast agent as a reference curve within the reference area from the series of angiographic recordings; obtaining trend patterns of the contrast agent from all areas of the angiographic recordings; determining the correlation between the trend patterns and the reference curve as a measure for the interrelationship between statistical variables, comparison with stored reference curve; comparison of the correlation coefficient with a threshold value; and reproduction of a marker identifying the myocardium.
摘要翻译：本发明涉及用于映射患者心肌的评估方法，特别是血管造影系列中的自动功能评估（例如心脏灌注），其步骤为：在将造影剂施用于患者之后直接记录一系列血管造影记录患者; 确定血管造影记录中的参考区域; 确定造影剂的趋势图案作为来自该系列血管造影记录的参考区域内的参考曲线; 从血管造影记录的所有区域获得造影剂的趋势图; 确定趋势模式和参考曲线之间的相关性，作为统计变量之间相互关系的度量，与存储的参考曲线进行比较; 相关系数与阈值的比较; 以及识别心肌的标记物的繁殖。

48. 发明授权

US07916827B2 Method for evaluating projection datasets of an object undergoing examination 有权
标题翻译：评估正在进行检查的物体的投影数据集的方法
公开(公告)号：US07916827B2
公开(公告)日：2011-03-29
申请号：US11824456
申请日：2007-06-29
申请人： Jan Boese , Günter Lauritsch , Thomas Redel
发明人： Jan Boese , Günter Lauritsch , Thomas Redel
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B6/4441 , Y10S378/901
摘要： The invention relates to a method for evaluating projection datasets of an object undergoing examination. Each projection dataset is assigned a swiveling angle and a recording instant. Each data element of each projection dataset defines a projection line along which an X-ray beam has traveled from an X-ray source to an X-ray detector. The projection datasets form recording groups each of which corresponds with the projection datasets that were recorded during a single swiveling action. A computer determines reconstruction datasets using the projection datasets. Each reconstruction dataset contains at least one reconstruction data value assigned to a reconstruction line. Using a temporal interpolation, the computer determines the reconstruction datasets in such a way that they refer to a uniform reconstruction time. The computer determines a reconstruction of the object undergoing examination using the reconstruction datasets.
摘要翻译：本发明涉及一种用于评估正在进行检查的对象的投影数据集的方法。每个投影数据集被分配一个旋转角度和一个记录时刻。每个投影数据集的每个数据元素定义了X射线束从X射线源行进到X射线检测器的投影线。投影数据集形成记录组，每个记录组与在单次旋转动作期间记录的投影数据集相对应。计算机使用投影数据集确定重建数据集。每个重建数据集包含分配给重建线的至少一个重建数据值。使用时间插值，计算机以这样的方式确定重建数据集，即它们指的是统一的重建时间。计算机使用重建数据集确定正在进行检查的对象的重建。

49. 发明授权

US07899223B2 Method and device for generating a three-dimensional image data record of a moving object by means of X-ray tomography 有权
标题翻译：用于通过X射线层析成像生成运动物体的三维图像数据记录的方法和装置
公开(公告)号：US07899223B2
公开(公告)日：2011-03-01
申请号：US11238552
申请日：2005-09-29
申请人： Jan Boese , Günter Lauritsch
发明人： Jan Boese , Günter Lauritsch
IPC分类号： G06K9/00 , A61B6/00
CPC分类号： G06T11/005 , A61B5/0402 , A61B5/0456 , A61B5/7207 , A61B6/02 , A61B6/032 , A61B6/503 , A61B6/504 , A61B6/541 , G06T2211/412 , G06T2211/421
摘要： A precise and comparatively simple method for generating a three-dimensional image data record of a moving object using X-ray tomography and a device that is particularly suitable for implementing the method with an X-ray emitter/detector unit supported such that it can be rotated and with an evaluation unit are specified. According to the invention a number of two-dimensional raw images are grouped according to a cyclical relative time, at least two preliminary 3D image data records respectively are generated from raw images that correspond to one another according to this grouping, at least one movement matrix is derived by comparing two preliminary 3D image data records used as the source data record and the target data record respectively, a 3D image data record with compensation for movement corresponding to a reference time of the source data record is generated by applying the or each movement matrix to the associated target data record and the or each 3D image data record with compensation for movement is added to at least one further 3D image data record with compensation for movement or to another preliminary 3D-image data record corresponding to the same reference time.
摘要翻译：一种用于使用X射线层析成像生成运动物体的三维图像数据记录的精确且相对简单的方法，以及特别适合于利用支持X射线发射器/检测器单元来实现该方法的装置，使得其可以指定了旋转和评估单元。根据本发明，根据循环相对时间对多个二维原始图像进行分组，根据该分组，从原始图像分别生成至少两个初步3D图像数据记录，至少一个运动矩阵是通过比较分别用作源数据记录和目标数据记录的两个初步3D图像数据记录，通过应用该或每个运动来生成具有与源数据记录的参考时间相对应的运动补偿的3D图像数据记录矩阵到相关联的目标数据记录，并且具有用于移动补偿的每个3D图像数据记录被添加到具有补偿移动的至少一个另外的3D图像数据记录或对应于相同参考时间的另一初步3D图像数据记录。

50. 发明申请

US20100239148A1 Method and System for Automatic Aorta Segmentation 有权
标题翻译：自动主动脉分割的方法和系统
公开(公告)号：US20100239148A1
公开(公告)日：2010-09-23
申请号：US12725679
申请日：2010-03-17
申请人： Yefeng Zheng , Bogdan Georgescu , Matthias John , Jan Boese , Dorin Comaniciu
发明人： Yefeng Zheng , Bogdan Georgescu , Matthias John , Jan Boese , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06K9/4638 , G06K2209/051 , G06T7/12 , G06T2200/04 , G06T2207/10081 , G06T2207/30101
摘要： A method and system for aorta segmentation in a 3D volume, such as a C-arm CT volume is disclosed. The aortic root is detected in the 3D volume using marginal space learning (MSL) based segmentation. The aortic arch is detected in the 3D volume using MSL based segmentation. The ascending aorta is tracked from the aortic root to the aortic arch in the 3D volume, and the descending aorta is tracked from the aortic arch in the 3D volume.
摘要翻译：公开了一种用于3D体积中的主动脉分割的方法和系统，例如C臂CT体积。使用基于边缘空间学习（MSL）的分割在3D体积中检测主动脉根部。使用基于MSL的分割在3D体积中检测主动脉弓。升主动脉从主动脉根部追溯到3D体积中的主动脉弓，并且主动脉弓从3D体积中跟踪降主动脉。

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