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41. 发明授权

US09237030B2 Solutions for upstream channel bonding 有权
标题翻译：上游通道结合的解决方案
公开(公告)号：US09237030B2
公开(公告)日：2016-01-12
申请号：US13589444
申请日：2012-08-20
申请人： Niki Pantelias , Lisa Denney , Edward Boyd , Andres Alvarez , Scott Hollums
发明人： Niki Pantelias , Lisa Denney , Edward Boyd , Andres Alvarez , Scott Hollums
IPC分类号： H04L12/28
CPC分类号： H04L12/2801 , H04L12/2869 , H04L12/2898
摘要： A cable modem that supports stateless requesting and/or limited contention-based requesting is provided herein. In an example, a physical layer (PHY) configured to communicate over a plurality of upstream channels is provided. A bandwidth requester is provided to request bandwidth using contention-based requesting over a first subset of the upstream channels for contention-based flows and request bandwidth using stateless requesting over a second subset of the upstream channels for stateless flows.
摘要翻译：本文提供支持无状态请求和/或有限争用请求的电缆调制解调器。在一个示例中，提供了经配置以在多个上行信道上进行通信的物理层（PHY）。提供带宽请求者以使用基于竞争的请求以上述信道的第一子集为基于竞争的流来请求带宽，并使用无状态请求通过无状态流的上行信道的第二子集来请求带宽。

42. 发明申请

US20100120840A1 Heterocyclic benzylamino derivatives, their manufacture and use as pharmaceutical agents 失效
公开(公告)号：US20100120840A1
公开(公告)日：2010-05-13
申请号：US11989272
申请日：2006-07-28
申请人： Edward Boyd , Frederick Brookfield , Jonathan Gridley , Konrad Honold , Raymond Lau , Stefan Scheiblich
发明人： Edward Boyd , Frederick Brookfield , Jonathan Gridley , Konrad Honold , Raymond Lau , Stefan Scheiblich
IPC分类号： A61K31/437 , C07D471/04 , A61P35/00 , A61P37/02
CPC分类号： C07D471/04
摘要： Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

43. 发明申请

US20080076736A1 COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF 审中-公开
标题翻译：含有抑制性卵巢囊虫病的组合物及其用途
公开(公告)号：US20080076736A1
公开(公告)日：2008-03-27
申请号：US11834505
申请日：2007-08-06
申请人： John Goddard , Donald Picker , Samuil Umansky , Steven Price , Jac Wijkmans , Edward Boyd , Anthony Baxter
发明人： John Goddard , Donald Picker , Samuil Umansky , Steven Price , Jac Wijkmans , Edward Boyd , Anthony Baxter
IPC分类号： A61K31/66 , A61P43/00 , C07F9/02 , C12N5/06
CPC分类号： C07F9/091
摘要： The invention provides anti-apoptotic compositions containing lysophosphatidic acids and methods for making and using the compositions. Such compositions may also contain LPA potentiating agents, including proteins, lipid membrane structures and polymers such as polyethylene glycols. The compositions can additionally contain other pharmaceutically effective agents such as drugs, antibiotics, wound healing agents and antioxidants.
摘要翻译：本发明提供含有溶血磷脂酸的抗凋亡组合物和制备和使用组合物的方法。此类组合物还可含有LPA增效剂，包括蛋白质，脂质膜结构和聚合物如聚乙二醇。组合物可另外含有其它药学上有效的试剂，例如药物，抗生素，伤口愈合剂和抗氧化剂。

44. 发明申请

US20070232681A1 Compounds Having Crth2 Antagonist Activity 审中-公开
公开(公告)号：US20070232681A1
公开(公告)日：2007-10-04
申请号：US10573670
申请日：2004-10-13
申请人： David Middlemiss , Mark Ashton , Edward Boyd , Frederick Brookfield , Richard Armer , Eric Pettipher
发明人： David Middlemiss , Mark Ashton , Edward Boyd , Frederick Brookfield , Richard Armer , Eric Pettipher
IPC分类号： A61K31/40 , A61K31/405 , C07D209/04 , C07D209/34
CPC分类号： C04B35/632 , C07D209/30 , C07D401/12 , C07D403/12 , C07D417/12
摘要： Compounds of general formula (I): wherein R1, R2, R3 and R4 are independently hydrogen, halo, C1-C6 alkyl, —O(C1-C6 alkyl), —CON(R9)2, —SOR9, —SO2R9, —SO2N(R9)2, —N(R9)2, —NR9COR9, —CO2R9, —COR9, —SR9, —OH, —NO2 or —CN; each R9 is independently hydrogen or C1-C6 alkyl; R5 and R6 are each independently hydrogen, or C1-C6 alkyl or together with the carbon atom to which they are attached form a C3-C7 cycloalkyl group; R7 is hydrogen or C1-C6 alkyl n is 1 or 2; X is a bond or, when n is 2, X may also be a NR9 group; wherein R9 is as defined above; when X is a bond R8 is C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, biphenyl or a 9-14 membered bicyclic or tricyclic heteroaryl group; when X is a NR9 group R8 may additionally be phenyl, naphthyl or a 5-7 membered heteroaromatic ring; and the R8 group is optionally substituted with one or more substituents selected from halo, C1-C6 alkyl, —O(C1-C6)alkyl, aryl, —O-aryl, heteroaryl, —O-heteroaryl, —CON(R9)2, —SOR9, —SO2R9, SO2N(9)2, —N(9)2, —NR9COR9, —CO2R9, —COR9, —SR9, —OH, —NO2 or —CN; wherein R9 is as defined above; and their pharmaceutically acceptable salts, hydrates, solvates, complexes and prodrugs are useful in the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.

45. 发明申请

US20060257149A1 Method and apparatus for accommodating multiple optical segments in an Ethernet passive optical network 审中-公开
标题翻译：用于在以太网无源光网络中容纳多个光纤段的方法和装置
公开(公告)号：US20060257149A1
公开(公告)日：2006-11-16
申请号：US11130731
申请日：2005-05-16
申请人： Ryan Hirth , Edward Boyd , Hoa Phan
发明人： Ryan Hirth , Edward Boyd , Hoa Phan
IPC分类号： H04J14/00
CPC分类号： H04J14/02 , H04B10/272
摘要： One embodiment of the present invention provides a system that accommodates multiple optical segments in an Ethernet passive optical network (EPON), wherein the EPON includes a central node and a number of remote nodes, and wherein the remote nodes reside in a number of optical segments. During operation, the system transmits downstream data from the central node to the remote nodes by broadcasting the data to the optical segments. In addition, the system selectively allows an optical segment to communicate with the central node during an upstream transmission period assigned to a remote node residing in that optical segment, thereby accommodating multiple optical segments and hence an increased number of remote nodes within the EPON.
摘要翻译：本发明的一个实施例提供了一种在以太网无源光网络（EPON）中容纳多个光纤段的系统，其中EPON包括中央节点和多个远程节点，并且其中远程节点驻留在多个光纤段。在运行期间，系统通过将数据广播到光段，从中央节点向远程节点发送下行数据。此外，该系统选择性地允许光学段在分配给驻留在该光学段中的远程节点的上行传输周期期间与中央节点进行通信，由此容纳多个光段，并因此容纳EPON内的远程节点的数量增加。

46. 发明申请

US20060097479A1 Fifth wheel king pin release mechanism having additional functions 失效
公开(公告)号：US20060097479A1
公开(公告)日：2006-05-11
申请号：US10982214
申请日：2004-11-05
申请人： William Hollis , William Hollis , Edward Boyd
发明人： William Hollis , William Hollis , Edward Boyd
IPC分类号： B62D53/06
CPC分类号： B62D53/08
摘要： A manual release mechanism for disengaging a king pin on a truck trailer from a fifth wheel of a truck cab includes a substantially straight lever arm with a first end being pivotally attached to the fifth wheel and a second end being spaced away from the fifth wheel extending horizontally from the first end. A pair of flat disks and a pair of slide bars are provided for slideably coupling to a release rod of the fifth wheel, such that a manual movement of the second end of the lever arm will cause pivoting thereof horizontally about the first end, thereby causing the release rod to be pulled outwardly to disengage the king pin from the fifth wheel. The lever arm is provided with an adjustable extension arm so that the length of the lever arm can be adjusted to an extent desired to best facilitate manipulation thereof. A lock pin is provided for securing the extension arm to the lever arm. A flexible cable secures the extension arm to the frame of the truck cab.

47. 发明申请

US20050119268A1 Treatment of CRTH2-mediated diseases and conditions 有权
标题翻译：治疗CRTH2介导的疾病和病症
公开(公告)号：US20050119268A1
公开(公告)日：2005-06-02
申请号：US10972060
申请日：2004-10-22
申请人： David Middlemiss , Mark Ashton , Edward Boyd , Frederick Brookfield
发明人： David Middlemiss , Mark Ashton , Edward Boyd , Frederick Brookfield
IPC分类号： A61K31/404 , A61K31/426 , A61K31/428 , A61K31/4709 , A61K31/498 , C07D209/08 , C07D209/10 , C07D209/12 , C07D401/06 , C07D403/06 , C07D417/06 , A61K31/405 , A61K31/427 , C07D417/02 , C07D43/02
CPC分类号： C07D209/12 , A61K31/404 , A61K31/426 , A61K31/428 , A61K31/4709 , A61K31/498 , C07D209/08 , C07D209/10 , C07D401/06 , C07D403/06 , C07D417/06
摘要： The present invention provides indole derivatives that antagonize prostaglandin D2, and that can be used to treat inflammatory diseases mediated by prostaglandin D2.
摘要翻译：本发明提供了拮抗前列腺素D 2 N的吲哚衍生物，其可用于治疗由前列腺素D 2 2介导的炎性疾病。

48. 发明申请

US20050047783A1 Method and apparatus for dynamically allocating upstream bandwidth in passive optical networks 失效
标题翻译：在无源光网络中动态分配上行带宽的方法和装置
公开(公告)号：US20050047783A1
公开(公告)日：2005-03-03
申请号：US10930336
申请日：2004-08-30
申请人： John Sisto , Edward Boyd
发明人： John Sisto , Edward Boyd
IPC分类号： H04L12/56 , H04Q11/00 , H04J14/00
CPC分类号： H04L47/27 , H04L47/15 , H04L47/22 , H04L47/2425 , H04L47/36 , H04L47/70 , H04L47/745 , H04L47/788 , H04L47/808 , H04Q11/0066 , H04Q11/0067 , H04Q2011/0064
摘要： One embodiment of the present invention provides a system that facilitates dynamic allocation of upstream bandwidth in a passive optical network which includes a central node and at least one remote node. Each remote node is coupled to at least one logical entity and includes a number of queues, each of which is associated with a logical entity and stores upstream data from the logical entity. The central node is coupled to an external network through a shared out-going uplink. During operation, the system receives a request from a remote node for a grant to transmit upstream data from a logical entity, wherein the request reports the state of a queue associated with a logical entity; wherein the size of the data to be transmitted does not exceed a transmission threshold assigned to that logical entity, and wherein a logical entity may not request more than what is allowed by the corresponding transmission threshold. If the request satisfies a bandwidth allocation policy, the system issues a grant to the remote node to transmit upstream data. In response to the grant, the system receives upstream data from the remote node. Next, the system transmits the received upstream data to the out-going uplink according to a set of SLAs.
摘要翻译：本发明的一个实施例提供了一种有助于在包括中央节点和至少一个远程节点的无源光网络中动态分配上行带宽的系统。每个远程节点耦合到至少一个逻辑实体并且包括多个队列，每个队列与逻辑实体相关联并且存储来自逻辑实体的上行数据。中央节点通过共享的外部上行链路耦合到外部网络。在操作期间，系统从远程节点接收用于从逻辑实体发送上行数据的许可的请求，其中所述请求报告与逻辑实体相关联的队列的状态; 其中要发送的数据的大小不超过分配给该逻辑实体的传输阈值，并且其中逻辑实体可以不超过相应的传输阈值允许的请求。如果请求满足带宽分配策略，则系统向远程节点发出授权以发送上行数据。响应于授权，系统从远程节点接收上游数据。接下来，系统根据一组SLA将接收到的上行数据发送到前进上行链路。

49. 发明授权

US06449291B1 Method and apparatus for time synchronization in a communication system 失效
标题翻译：通信系统中时间同步的方法和装置
公开(公告)号：US06449291B1
公开(公告)日：2002-09-10
申请号：US09199030
申请日：1998-11-24
申请人： Lawrence M. Burns , Edward Boyd
发明人： Lawrence M. Burns , Edward Boyd
IPC分类号： H04J306
CPC分类号： H04L12/2801 , H04J3/0655 , H04L47/28
摘要： A method and apparatus for time synchronization in a communications system such as a system including cable modems is provided. The synchronization method comprises the steps of receiving a first timestamp from a headend unit with the cable modem, and generating a first cable modem time reference with the cable modem in response to the receipt of the first timestamp. The cable modem then receives a second timestamp from the headend unit and generates a second cable modem time reference in response to the receipt of the second timestamp. A headend difference time comprising the difference of the first and second timestamps is then generated as is a cable modem difference time comprising the difference of the first and second cable modem time references. A clock error time that comprises the difference of the headend difference time and the cable modem difference time is then generated as well as a correction factor in response to the clock error time. The local clock of the cable modem is then synchronized with the master clock of the headend unit through the adjusting of the output of the local clock output in response to the correction factor. The correction factor in one instance comprises an offset value representative of the amount of clock error per local clock pulse. This offset value is added to an accumulator on each local clock pulse, and the local clock output is adjusted when the accumulator rolls over. The synchronized clock signal can then be utilized to determine a time slot in which the cable modem can transmit an upstream signal to the headend without colliding the upstream signal with upstream signals from other modems in the system.
摘要翻译：提供了一种用于诸如包括电缆调制解调器的系统的通信系统中的时间同步的方法和装置。所述同步方法包括以下步骤：从所述电缆调制解调器的头端单元接收第一时间戳，以及响应于接收到所述第一时间戳，与所述电缆调制解调器生成第一电缆调制解调器时间参考。电缆调制解调器然后从头端单元接收第二时间戳，并且响应于接收到第二时间戳而产生第二电缆调制解调器时间基准。然后产生包括第一和第二时间戳的差的前端差时间，以及包括第一和第二电缆调制解调器时间基准的差异的电缆调制解调器差分时间。然后产生包括前端差时间和电缆调制解调器差时间的差的时钟错误时间以及响应于时钟错误时间的校正因子。然后电缆调制解调器的本地时钟通过响应于校正因子调整本地时钟输出的输出而与前端单元的主时钟同步。一个实例中的校正因子包括表示每个本地时钟脉冲的时钟误差量的偏移值。该偏移值被加到每个本地时钟脉冲的累加器上，当累加器翻转时，调整本地时钟输出。然后可以利用同步的时钟信号来确定电缆调制解调器可以向前端发送上行信号的时隙，而不会使上游信号与系统中其他调制解调器的上行信号相冲突。

50. 外观设计

USD451039S1 Accelerometer 失效
标题翻译：加速度计
公开(公告)号：USD451039S1
公开(公告)日：2001-11-27
申请号：US29131281
申请日：2000-10-13
申请人： Steven L. King , Edward Boyd
设计人： Steven L. King , Edward Boyd

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