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    • 41. 发明申请
    • CELLS FOR THE TREATMENT OF NERVOUS SYSTEM DISORDERS
    • 用于治疗神经系统疾病的细胞
    • US20120009160A1
    • 2012-01-12
    • US13233701
    • 2011-09-15
    • Mari DEZAWAHajime SawadaHiroshi KannoMasahiko Takano
    • Mari DEZAWAHajime SawadaHiroshi KannoMasahiko Takano
    • A61K35/28A61P25/00
    • C12N5/0619A61K9/0085A61K35/28A61K35/30A61K2035/124C12N5/0618C12N5/0658C12N5/0663C12N2501/42C12N2502/1358C12N2506/1353C12N2510/00
    • There is provided a method of inducing differentiation of bone marrow stromal cells to neural cells or skeletal muscle cells by introduction of a Notch gene. Specifically, the invention provides a method of inducing differentiation of bone marrow stromal cells to neural cells or skeletal muscle cells in vitro, which method comprises introducing a Notch gene and/or a Notch signaling related gene into the cells, wherein the finally obtained differentiated cells are the result of cell division of the bone marrow stromal cells into which the Notch gene and/or Notch signaling related gene have been introduced. The invention also provides a method of inducing further differentiation of the differentiation-induced neural cells to dopaminergic neurons or acetylcholinergic neurons. The invention yet further provides a treatment method for neurodegenerative and skeletal muscle degenerative diseases which employs neural precursor cells, neural cells or skeletal muscle cells produced by the method of the invention.
    • 提供了通过引入Notch基因诱导骨髓基质细胞分化为神经细胞或骨骼肌细胞的方法。 具体地说,本发明提供了一种在体外诱导骨髓基质细胞分化为神经细胞或骨骼肌细胞的方法,该方法包括将Notch基因和/或Notch信号传导相关基因引入细胞,其中最终获得的分化细胞 是引入了Notch基因和/或Notch信号传导相关基因的骨髓基质细胞的细胞分裂的结果。 本发明还提供了诱导分化诱导的神经细胞进一步分化为多巴胺能神经元或乙酰胆碱能神经元的方法。 本发明还进一步提供了一种神经变性和骨骼肌退行性疾病的治疗方法,其采用通过本发明的方法生产的神经前体细胞,神经细胞或骨骼肌细胞。
    • 43. 发明授权
    • Walking exercise supporting device
    • 步行运动辅助装置
    • US08021271B2
    • 2011-09-20
    • US12585954
    • 2009-09-29
    • Kouichirou KasamaHiroshi Kanno
    • Kouichirou KasamaHiroshi Kanno
    • A63B71/00
    • G01C21/20
    • A device can search for an appropriate walking route with an exercise condition such as of the calorie consumption and the walking speed. When a user enters information at least on the walking time, calorie consumption, walking speed, and distance as the exercise condition, the exercise condition is stored in a data storage unit of the device. When the user enters position information on the walking start point and the walking end point, the position information is also stored in the storage unit of the device. Map information is also previously stored in the data storage unit. A route searching unit of the device searches for the walking route and determines it according to the stored exercise condition, the position information and the map information. The determined walking route is presented to the user through a presenting unit of the device.
    • 设备可以搜索具有诸如卡路里消耗和步行速度的运动条件的适当的步行路线。 当用户至少在步行时间,卡路里消耗,步行速度和作为锻炼条件的距离时输入信息时,训练条件被存储在设备的数据存储单元中。 当用户输入步行起点和步行终点的位置信息时,位置信息也存储在装置的存储单元中。 地图信息也预先存储在数据存储单元中。 设备的路径搜索单元搜索步行路线,并根据存储的运动条件,位置信息和地图信息来确定。 所确定的步行路线通过设备的呈现单元呈现给用户。
    • 46. 发明申请
    • Walking exercise supporting device
    • 步行运动辅助装置
    • US20100022352A1
    • 2010-01-28
    • US12585954
    • 2009-09-29
    • Kouichirou KasamaHiroshi Kanno
    • Kouichirou KasamaHiroshi Kanno
    • A63B71/00
    • G01C21/20
    • A device can search for an appropriate walking route with an exercise condition such as of the calorie consumption and the walking speed. When a user enters information at least on the walking time, calorie consumption, walking speed, and distance as the exercise condition, the exercise condition is stored in a data storage unit of the device. When the user enters position information on the walking start point and the walking end point, the position information is also stored in the storage unit of the device. Map information is also previously stored in the data storage unit. A route searching unit of the device searches for the walking route and determines it according to the stored exercise condition, the position information and the map information. The determined walking route is presented to the user through a presenting unit of the device.
    • 设备可以搜索具有诸如卡路里消耗和步行速度的运动条件的适当的步行路线。 当用户至少在步行时间,卡路里消耗,步行速度和作为锻炼条件的距离时输入信息时,训练条件被存储在设备的数据存储单元中。 当用户输入步行起点和步行终点的位置信息时,位置信息也存储在装置的存储单元中。 地图信息也预先存储在数据存储单元中。 设备的路径搜索单元搜索步行路线,并根据存储的运动条件,位置信息和地图信息来确定。 所确定的步行路线通过设备的呈现单元呈现给用户。
    • 47. 发明授权
    • Wide-band slot antenna apparatus with constant beam width
    • 具有恒定波束宽度的宽带缝隙天线装置
    • US07642981B2
    • 2010-01-05
    • US12117535
    • 2008-05-08
    • Hiroshi KannoTomoyasu Fujishima
    • Hiroshi KannoTomoyasu Fujishima
    • H01Q13/10
    • H01Q13/10H01Q13/106
    • A slot antenna apparatus including: a grounding conductor having an outer edge including a first portion facing a radiation direction and a second portion other than the first portion, a one-end-open slot formed in the grounding conductor along the radiation direction such that an open end is provided at a center of the first portion, and a feed line including a strip conductor close to the grounding conductor and intersecting with the slot at least a part thereof to feed a radio frequency signal to the slot. The grounding conductor is formed to include at least one section at the second portion, the at least one section gradually approaches an axis passing through the slot and parallel to the radiation direction with increasing distance from the first portion.
    • 一种缝隙天线装置,包括:接地导体,其具有包括面向辐射方向的第一部分的外边缘和除了所述第一部分之外的第二部分,沿着所述辐射方向形成在所述接地导体中的一端开口槽, 开口端设置在第一部分的中心,以及馈电线,其包括靠近接地导体的带状导体,并且至少与其一部分相交,以将射频信号馈送到狭槽。 接地导体被形成为在第二部分处包括至少一个部分,至少一个部分逐渐接近穿过狭槽并平行于辐射方向的轴线,随着距离第一部分的距离的增加。
    • 49. 发明申请
    • ENDFIRE ANTENNA APPARATUS WITH MULTILAYER LOADING STRUCTURES
    • 端面天线装置与多层装载结构
    • US20090195460A1
    • 2009-08-06
    • US12361737
    • 2009-01-29
    • Hiroshi Kanno
    • Hiroshi Kanno
    • H01Q1/38H01Q13/00
    • H01Q1/243H01Q1/38H01Q13/28
    • A plurality of conductive strip elements compose multilayer loading structures on top and bottom surfaces of a dielectric transmission substrate, by which a part of intra-substrate transmission components of a electromagnetic wave are leaked out of the surfaces. Each multilayer loading structure includes a first conductive strip group of conductive strip elements within a first plane, and a second conductive strip group of conductive strip elements within a second plane, and the first and second conductive strip groups are formed to be capacitively coupled to each other. In each of the first and second conductive strip groups, the conductive strip elements are placed at intervals of a distance of a quarter or less of a reference adjacent distance, where the reference adjacent distance is defined as a distance for generating spatial harmonics of the electromagnetic wave on the surfaces of the dielectric transmission substrate.
    • 多个导电带状元件在电介质传输基板的顶表面和底表面上构成多层加载结构,电磁波的一部分基板内传输分量从该表面泄漏出表面。 每个多层加载结构包括在第一平面内的导电条带元件的第一导电条带组和第二平面内的导电条带元件的第二导电条带组,并且第一和第二导电条带组被形成为电容耦合到每个 其他。 在每个第一和第二导电条带组中,导电条带元件以参考相邻距离的四分之一或更小的距离放置,其中参考相邻距离被定义为用于产生电磁空间谐波的距离 在电介质传输基板的表面上形成波。