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41. 发明授权

US4567838A Apparatus and process for dropping feed dog and lifting presser foot simultaneously 失效
标题翻译：用于同时放下饲料狗和起重压脚的装置和方法
公开(公告)号：US4567838A
公开(公告)日：1986-02-04
申请号：US586859
申请日：1984-03-06
申请人： Peter Vogel
发明人： Peter Vogel
IPC分类号： D05B27/24 , D05B29/02
CPC分类号： D05B27/24
摘要： The lifting device (19) of the presser foot (21) of a sewing machine is operable through the use of an operating axle (18) and a toggle lever (20). The operating axle (18) is connected to a slide (15) capable of engaging and disengaging a coupling mechanism (10). The coupling mechanism (10) is arranged between the lifting device (6) of the feed dog (3) and the oscillating drive means (7) of the lifting device. During the lifting of the presser foot (21) by means of the toggle lever (20), the coupling pin (12) of the coupling mechanism (10) is simultaneously placed out of engagement with the driven oscillating lever (8) by means of the slide (15). Thus the drive of the lifting device (6) is interrupted, and a spring (13) pulls the feed dog (3) into its lowered position. Thus the manipulation of the sewing material is made possible without the feed dog presenting an obstacle.
摘要翻译：缝纫机的压脚（21）的提升装置（19）可通过使用操作轴（18）和肘节杆（20）来操作。操作轴（18）连接到能够接合和分离联接机构（10）的滑块（15）。联接机构（10）布置在进料斗（3）的提升装置（6）和提升装置的振动驱动装置（7）之间。在通过肘杆（20）提升压脚（21）期间，联接机构（10）的联接销（12）同时被放置在与被驱动的摆动杆（8）的啮合之外，借助于幻灯片（15）。因此，提升装置（6）的驱动被中断，并且弹簧（13）将进给爪（3）拉到其降低的位置。因此，无需进给狗出现障碍就可以进行缝制材料的操作。

42. 发明授权

US4477575A Process and composition for separating plasma or serum from whole blood 失效
标题翻译：从全血中分离血浆或血清的方法和组成
公开(公告)号：US4477575A
公开(公告)日：1984-10-16
申请号：US289943
申请日：1981-08-04
申请人： Peter Vogel , Hans-Peter Braun , Dieter Berger , Wolfgang Werner
发明人： Peter Vogel , Hans-Peter Braun , Dieter Berger , Wolfgang Werner
IPC分类号： A61K35/14 , A61M1/00 , B01D39/20 , G01N33/48 , G01N33/49 , G01N33/52 , G01N1/18
CPC分类号： G01N33/491 , B01D39/2017 , G01N33/48 , G01N33/525 , Y10T436/25375
摘要： A composition and process for permitting the separation of plasma or serum from whole blood. The composition includes glass fibers having an average diameter of from 0.2.mu. to 5.mu. and a density of 0.1 g/cm.sup.2 to 0.5 g/cm.sup.2. The process includes the steps of slowly trickling whole blood onto one side of a layer composed of the composition of glass fibers, whereby plasma or serum separated from the blood becomes available at another side of the layer. The total volume of the plasma or serum separated from the blood is limited to at most 50% of the absorption volume of the glass fiber layer.
摘要翻译：允许血浆或血清从全血分离的组合物和方法。该组合物包含平均直径为0.2〜5μm，密度为0.1g / cm 2〜0.5g / cm 2的玻璃纤维。该方法包括以下步骤：将全血慢慢滴入由玻璃纤维组合物组成的层的一侧，从血液中分离的血浆或血清在层的另一侧可用。从血液分离的血浆或血清的总体积被限制在玻璃纤维层的吸收体积的至多50％。

43. 发明授权

US4385114A Oxidation indicators comprising 3,3',5,5'-tetraalkylbenzidine compounds 失效
标题翻译：包含3,3'，5,5'-四烷基联苯胺化合物的氧化指示剂
公开(公告)号：US4385114A
公开(公告)日：1983-05-24
申请号：US236487
申请日：1981-02-23
申请人： Werner Guthlein , Walter Rittersdorf , Hugo Tiedemann , Peter Vogel , Wolfgang Werner
发明人： Werner Guthlein , Walter Rittersdorf , Hugo Tiedemann , Peter Vogel , Wolfgang Werner
IPC分类号： C07C211/50 , C07C67/00 , C07C209/00 , C07C209/54 , C12Q1/00 , C12Q1/26 , C12Q1/28 , G01N21/78 , G01N31/00 , G01N31/22 , G01N33/50 , C12Q1/60 , C12Q1/62
CPC分类号： C12Q1/26 , C12Q1/28 , G01N31/228 , C12Q2326/10 , C12Q2326/12 , Y10S435/805 , Y10S436/81 , Y10T436/144444 , Y10T436/206664
摘要： The detection and determination of (a) hydrogen peroxide or of a substance which reacts with the formation of hydrogen peroxide or (b) of peroxidase or a peroxidatively active substance, is carried out by contacting an unknown sample with a chromogen and, in case (a), with a peroxidatively active substance or in case (b) with hydrogen peroxide or a substance which reacts with the formation of hydrogen peroxide, and evaluating the coloration produced by the reaction, wherein, as the chromogen, there is used at least one 3,3',5,5'-tetraalkylbenzidine compound of the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which can be the same or different, are straight-chained or branched alkyl radicals containing up to 6 and preferably up to 4 carbon atoms.
摘要翻译：（a）过氧化氢或与过氧化氢或过氧化物酶或过氧化物活性物质的（b）反应形成的物质的检测和测定是通过将未知样品与色原体接触进行的，如果（ a），具有过氧化活性物质或在（b）过氧化氢或与形成过氧化氢反应的物质的情况下，以及评价由反应产生的着色，其中作为色原，使用至少一种具有下式的3,3'，5,5'-四烷基联苯胺化合物：其中R 1，R 2，R 3和R 4可以相同或不同，是含有至多6个的直链或支链烷基，优选最多4个碳原子。

44. 发明授权

US3975398A 9-Substituted 3-aminocarbazole compounds 失效
标题翻译： 9-取代的3-氨基咔唑化合物
公开(公告)号：US3975398A
公开(公告)日：1976-08-17
申请号：US487338
申请日：1974-07-10
申请人： Wolfgang Werner , Peter Vogel , Hugo Tiedemann , Werner Guthlein
发明人： Wolfgang Werner , Peter Vogel , Hugo Tiedemann , Werner Guthlein
IPC分类号： C07D209/88 , C12Q1/28 , C12Q1/54 , G01N31/00 , G01N31/22 , G01N33/50 , G01N33/66 , G01N33/68
CPC分类号： C12Q1/28 , C07D209/88 , C12Q1/54 , C12Q2326/00 , C12Q2326/14 , Y10S436/81
摘要： Novel 3-aminocarbazole compounds of the formula: ##SPC1##WhereinX is hydrogen or halogen,Y is oxygen or represents two hydrogen atoms; andR.sub.1 and R.sub.2, which can be the same or different, are hydrogen, lower alkyl or hydroxyalkyl or amino; andn is 1 or 2, with the proviso that when n is 2, X, Y, R.sub.1 and R.sub.2 cannot all be hydrogen atoms,As well as the salts thereof with inorganic and organic acids; are outstandingly effective indicators for the determination of glucose and provide stable compositions for such glucose determination.
摘要翻译：新型3-氨基咔唑化合物，具有下式：

45. 发明授权

US10417059B1 Staged application programming interface 有权
公开(公告)号：US10417059B1
公开(公告)日：2019-09-17
申请号：US16054729
申请日：2018-08-03
申请人： Amit Arya , George Chiramattel Kunjachan , Peter Vogel , Tyler Riding , Jennifer Martin
发明人： Amit Arya , George Chiramattel Kunjachan , Peter Vogel , Tyler Riding , Jennifer Martin
IPC分类号： G06F9/54 , G06K9/62 , G06F16/21 , G06F16/2457
摘要： A method may include receiving, via a network and from a source application, partial data including values for parameters defined according to an application programming interface (API). Each parameter may be defined by the API as optional. The partial data may be incomplete for use by a target application. The method may further include obtaining a set of contextual data correlated with the partial data, generating augmented partial data by combining the partial data and contextual data selected from the set of contextual data, determining that the augmented partial data satisfies a transaction completion criterion of a transaction schema, and in response to determining that the augmented partial data satisfies the transaction completion criterion, sending the augmented partial data to a transaction store used by the target application.

46. 发明申请

US20120030776A1 NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO 审中-公开
标题翻译：新的基因破坏，组合物和方法相关
公开(公告)号：US20120030776A1
公开(公告)日：2012-02-02
申请号：US12910746
申请日：2010-10-22
申请人： Katherin E. Combs , Ling Ling Culbertson , Frederic de Sauvage , Zhiyong Ding , Joel Edwards , Rosemary Girgis , Allison Anne Byers Horner , Harald Junge , Jagath Reddy Junutula , Erin Marie Massey , Dina Rebecca McLain , Charles Montgomery , Bobby Joe Payne , Heidi Phillips , Ni Nancy Qian , Carolina Rangel , Tracy Ellen Willis Sevaux , Zheng-Zheng Shi , Mary Jean Sparks , Joy Anne Stala , Peter Vogel , Weilan Ye
发明人： Katherin E. Combs , Ling Ling Culbertson , Frederic de Sauvage , Zhiyong Ding , Joel Edwards , Rosemary Girgis , Allison Anne Byers Horner , Harald Junge , Jagath Reddy Junutula , Erin Marie Massey , Dina Rebecca McLain , Charles Montgomery , Bobby Joe Payne , Heidi Phillips , Ni Nancy Qian , Carolina Rangel , Tracy Ellen Willis Sevaux , Zheng-Zheng Shi , Mary Jean Sparks , Joy Anne Stala , Peter Vogel , Weilan Ye
IPC分类号： A61K49/00 , C12Q1/48 , C12Q1/42 , C40B30/04 , C12Q1/02
CPC分类号： A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/03 , C12N15/8509
摘要： The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO69122, PRO204, PRO214, PRO222, PRO234, PRO265, PRO309, PRO332, PRO342, PRO356, PRO540, PRO618, PRO944, PRO994, PRO1079, PRO1110, PRO1122, PRO1138, PRO1190, PRO1272, PRO1286, PRO1295, PRO1309, PRO1316, PRO1383, PRO1384, PRO1431, PRO1434, PRO1475, PRO1481, PRO1568, PRO1573, PRO1599, PRO1604, PRO1605, PRO1693, PRO1753, PRO1755, PRO1777, PRO1788, PRO1864, PRO1925, PRO1926, PRO3566, PRO4330, PRO4423, PRO36935, PRO4977, PRO4979, PRO4980, PRO4981, PRO5801, PRO5995, PRO6001, PRO6095, PRO6182, PRO7170, PRO7171, PRO7436, PRO9912, PRO9917, PRO37337, PRO37496, PRO19646, PRO21718, PRO19820, PRO21201, PRO20026, PRO20110, PRO23203 or PRO35250 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
摘要翻译：本发明涉及转基因动物，以及与基因功能表征相关的组合物和方法。具体地，本发明提供转基因小鼠，其包括PRO69122，PRO204，PRO214，PRO222，PRO234，PRO265，PRO309，PRO332，PRO342，PRO356，PRO540，PRO618，PRO944，PRO994，PRO1079，PRO1110，PRO1122，PRO1138，PRO1190，PRO1272中的中断，PRO1286，PRO1295，PRO1309，PRO1316，PRO1383，PRO1384，PRO1431，PRO1434，PRO1475，PRO1481，PRO1568，PRO1573，PRO1599，PRO1604，PRO1605，PRO1693，PRO1753，PRO1755，PRO1777，PRO1788，PRO1864，PRO1925，PRO1926，PRO3566，PRO4330 ，PRO4423，PRO36935，PRO4977，PRO4979，PRO4980，PRO4981，PRO5801，PRO5995，PRO6001，PRO6095，PRO6182，PRO7170，PRO7171，PRO7436，PRO9912，PRO9917，PRO37337，PRO37496，PRO19646，PRO21718，PRO19820，PRO21201，PRO20026，PRO20110，PRO23203 或PRO35250基因。这样的体内研究和表征可以提供有用的识别和发现治疗和/或治疗用于预防，改善或矫正与基因中断相关的疾病或功能障碍如神经障碍; 心血管，内皮或血管生成障碍; 眼睛异常; 免疫学障碍; 肿瘤疾病; 骨代谢异常或障碍; 脂代谢紊乱或发育异常。

47. 发明申请

US20110252485A1 Novel gene disruptions, compositions and methods relating thereto 审中-公开
标题翻译：与之相关的新型基因破坏，组合物和方法
公开(公告)号：US20110252485A1
公开(公告)日：2011-10-13
申请号：US13159202
申请日：2011-06-13
申请人： Frederic de Sauvage , Ellen Filvaroff , Jagath Reddy Junutula , Bobby Joe Payne , Zheng-Zheng Shi , Mary Jean Sparks , Peter Vogel
发明人： Frederic de Sauvage , Ellen Filvaroff , Jagath Reddy Junutula , Bobby Joe Payne , Zheng-Zheng Shi , Mary Jean Sparks , Peter Vogel
IPC分类号： A61K49/00
CPC分类号： G01N33/5088 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/03 , A01K2267/0306 , A01K2267/035 , C07K14/47 , C12N15/8509 , G01N33/6893 , G01N2500/00
摘要： The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO844, PRO1131 or PRO5992 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
摘要翻译：本发明涉及转基因动物，以及与基因功能表征相关的组合物和方法。具体地说，本发明提供包含PRO844，PRO1131或PRO5992基因中断的转基因小鼠。这样的体内研究和表征可以提供有用的识别和发现治疗和/或治疗用于预防，改善或矫正与基因中断相关的疾病或功能障碍如神经障碍; 心血管，内皮或血管生成障碍; 眼睛异常; 免疫学障碍; 肿瘤疾病; 骨代谢异常或障碍; 脂代谢紊乱或发育异常。

48. 发明申请

US20110200579A1 NOVEL GENE DISRUPTIONS, COMPOSITIONS AND METHODS RELATING THERETO 审中-公开
标题翻译：新的基因破坏，组合物和方法相关
公开(公告)号：US20110200579A1
公开(公告)日：2011-08-18
申请号：US12375668
申请日：2008-01-22
申请人： Jaime-Jo Cunningham , Peter Vogel
发明人： Jaime-Jo Cunningham , Peter Vogel
IPC分类号： A61K39/395 , G01N33/48 , C12N5/10 , C07K16/18 , C12Q1/02 , A61P3/10 , A61P9/10 , A61P35/00 , A61P17/02 , A61P19/02 , A61P37/00 , A61P7/00 , A61P19/10 , C12N5/00
CPC分类号： C12N15/8509 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0306
摘要： The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO57290 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as cardiovascular, endothelial or angiogenic disorders; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; or developmental abnormalities.
摘要翻译：本发明涉及转基因动物，以及与基因功能表征相关的组合物和方法。具体地，本发明提供包含PRO57290基因中断的转基因小鼠。这样的体内研究和表征可以提供有用的识别和发现用于预防，改善或矫正与基因破坏如心血管，内皮或血管生成障碍相关的疾病或功能障碍的治疗和/或治疗; 免疫学障碍; 肿瘤疾病; 骨代谢异常或障碍; 或发育异常。

49. 发明申请

US20110199198A1 Method for operating a heads-up display system, heads-up display system 审中-公开
标题翻译：用于操作平视显示系统，平视显示系统的方法
公开(公告)号：US20110199198A1
公开(公告)日：2011-08-18
申请号：US12931725
申请日：2011-02-08
申请人： Yiwen Yang , Lutz Bersiner , Mario Mueller-Frahm , Moez Selem , Peter Vogel , Gerrit De Boer , Andreas Engelsberg , Holger Modler
发明人： Yiwen Yang , Lutz Bersiner , Mario Mueller-Frahm , Moez Selem , Peter Vogel , Gerrit De Boer , Andreas Engelsberg , Holger Modler
IPC分类号： B60R25/10 , G09G5/00
CPC分类号： G02B27/01 , B60K35/00 , B60K2370/191 , B60K2370/193 , B60K2370/334 , B60R1/00 , B60R2300/308 , B60R2300/8093 , G02B2027/0138 , G02B2027/014 , G02B2027/0187
摘要： In a method for operating a heads-up display system of a vehicle, the roadway state of the roadway to be traveled by the vehicle is checked using at least one suitable sensor, and a warning message is displayed at a location on the windshield in the case of detection of a critical roadway state, the location of the warning message corresponding to the dangerous, driving area of the roadway as viewed from the driver's perspective.
摘要翻译：在一种用于操作车辆的平视显示系统的方法中，使用至少一个合适的传感器检查车辆行驶的道路的道路状态，并且在挡风玻璃上的位置显示警告消息从驾驶员的角度来看，检测到巷道状态的情况，对应于巷道的危险驾驶区域的警告信息的位置。

50. 发明申请

US20110191865A1 Novel Gene Disruptions, Compositions and Methods Relating Thereto 审中-公开
标题翻译：新型基因中断，组成和方法
公开(公告)号：US20110191865A1
公开(公告)日：2011-08-04
申请号：US11457708
申请日：2009-06-03
申请人： Joel A. Edwards , Wenhu Huang , Charles A. Montgomery , Ni Nancy Qian , Zheng-Zheng Shi , Mary Jean Sparks , Peter Vogel , Mindy Westbrook
发明人： Joel A. Edwards , Wenhu Huang , Charles A. Montgomery , Ni Nancy Qian , Zheng-Zheng Shi , Mary Jean Sparks , Peter Vogel , Mindy Westbrook
IPC分类号： G01N33/48 , A61K39/395 , C12Q1/02 , C12N5/10 , C12N5/071 , C07K16/18 , A61P35/00 , A61P25/00 , A61P9/00 , A61P3/00 , A61P37/02 , A61P25/24 , A61P25/22 , A61P25/18 , A61P27/02 , A61P27/06 , A61P27/12 , A61P3/10 , A61P9/10 , A61P9/04 , A61P9/12 , A61P29/00 , A61P19/02 , A61P19/10
CPC分类号： C07K14/47 , A01K2217/075
摘要： The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO227, PRO233, PRO238, PRO1328, PRO4342, PRO7423, PRO10096, PRO21384, PRO353 or PRO1885 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
摘要翻译：本发明涉及转基因动物，以及与基因功能表征相关的组合物和方法。具体地，本发明提供包含PRO227，PRO233，PRO238，PRO1328，PRO4342，PRO7423，PRO10096，PRO21384，PRO353或PRO1885基因中断的转基因小鼠。这样的体内研究和表征可以提供有用的识别和发现治疗和/或治疗用于预防，改善或矫正与基因中断相关的疾病或功能障碍如神经障碍; 心血管，内皮或血管生成障碍; 眼睛异常; 免疫学障碍; 肿瘤疾病; 骨代谢异常或障碍; 脂代谢紊乱或发育异常。

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