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41. 发明授权

US06775880B2 Protectant application 有权
标题翻译：保护应用
公开(公告)号：US06775880B2
公开(公告)日：2004-08-17
申请号：US10042603
申请日：2002-01-09
申请人： Gary A. Kasper , Samuel N. Hansen , John L. Jansen , Phong Hoang Tran , Eric J. Hansen , Gabriel S. Vander Baan
发明人： Gary A. Kasper , Samuel N. Hansen , John L. Jansen , Phong Hoang Tran , Eric J. Hansen , Gabriel S. Vander Baan
IPC分类号： A47L1130
CPC分类号： A47L11/4075 , A47L11/34 , A47L11/4083 , A47L11/4088 , Y10T137/0402
摘要： A hand-held nozzle is attached to the end of a vacuum and fluid delivery hose of an upright deep cleaner. The nozzle includes a reservoir to contain a solution to be applied to a surface. When a solution delivery system of the deep cleaner is pressurized, water from the upright cleaner clean water tank is routed through the hose to the hand-held nozzle. The water is routed through a venturi valve connected to the reservoir, which draws the solution to the valve to mix with the water stream. The resultant mixture flows from the hand-held nozzle for application to a surface being treated. One embodiment of the solution reservoir includes a retainer cap bonded to the reservoir and utilizing a bayonet-type mounting arrangement for mounting the reservoir to a nozzle assembly.
摘要翻译：手持式喷嘴连接到直立深度清洁器的真空和流体输送软管的端部。喷嘴包括容纳要施加到表面的溶液的储存器。当深度清洁剂的溶液输送系统被加压时，来自直立清洁剂的清洁水箱的水通过软管被引导到手持式喷嘴。水通过连接到储存器的文丘里阀，其将溶液抽吸到阀以与水流混合。所得混合物从用于施加的手持喷嘴流向被处理的表面。溶液储存器的一个实施例包括结合到储存器的保持器盖，并且利用卡口式安装装置将储存器安装到喷嘴组件。

42. 发明授权

US5981213A Methods and compositions relating to useful antigens of moraxella catarrhalis 失效
标题翻译：与卡他莫拉菌的有用抗原相关的方法和组合物
公开(公告)号：US5981213A
公开(公告)日：1999-11-09
申请号：US450351
申请日：1995-05-25
申请人： Eric J. Hansen , Merja E. Helminen , Isobel Maciver
发明人： Eric J. Hansen , Merja E. Helminen , Isobel Maciver
IPC分类号： A61K38/00 , A61K39/00 , A61P31/04 , C07K14/21 , C07K16/12 , C12P21/08 , C12P21/06 , C07H21/02 , C12N1/12 , C12N15/00
CPC分类号： C07K16/1203 , C07K14/212 , C07K16/1214 , C07K16/1217 , A61K2039/505 , A61K38/00 , A61K39/00
摘要： The present disclosure relates to Moraxella catarrhalis outer membrane vesicle (OMV) compositions, to selected antigenic proteins from the outer membranes of M. catarrhalis which have a variety of useful properties, and to monoclonal antibodies against these proteins. Particular "Outer Membrane Proteins" (OMPs) of the invention are characterized as having molecular weights of about 30 kD, 80 kD (also termed CopB protein) and between about 200 and 700 kD (HMWP antigen). Passive immunization with monoclonal antibodies directed against these proteins confers protection against homologous and heterologous Moraxella catarrhalis strains in animal models, and active immunization with outer membrane vesicles also enhances pulmonary clearance of distinct M. catarrhalis strains. This demonstrates both the utility of antibodies in conferring passive immunity and the usefulness of OMPs, or variants thereof, in the preparation of vaccines. Also disclosed are DNA segments encoding these OMPs, methods for preparing the antigens, or variants, through the application of recombinant DNA techniques, as well as diagnostic methods and related embodiments.
摘要翻译：本公开内容涉及卡他莫拉菌外膜囊泡（OMV）组合物，具有多种有用特性的卡他莫拉胶囊的外膜的选定抗原蛋白质以及针对这些蛋白质的单克隆抗体。本发明的特定的“外膜蛋白”（OMP）的特征在于具有约30kD，80kD（也称为CopB蛋白）和约200至700kD（HMWP抗原）的分子量。用针对这些蛋白质的单克隆抗体的被动免疫赋予动物模型中的同源和异源卡他莫拉菌株的保护，并且与外膜囊泡的主动免疫也增强了不同的卡他莫拉菌株的肺清除。这证明了抗体在赋予被动免疫中的效用以及OMP或其变体在制备疫苗中的用途。还公开了编码这些OMP的DNA片段，通过应用重组DNA技术制备抗原或变体的方法，以及诊断方法和相关实施方案。

43. 发明授权

US5356778A Method for detection of gram-negative bacterial liposaccharides in biological fluids 失效
标题翻译：检测生物体液中革兰氏阴性细菌脂肪糖的方法
公开(公告)号：US5356778A
公开(公告)日：1994-10-18
申请号：US972498
申请日：1993-02-05
申请人： Eric J. Hansen , Robert S. Munford , Jussi Mertsola
发明人： Eric J. Hansen , Robert S. Munford , Jussi Mertsola
IPC分类号： G01N33/53 , G01N33/569 , G01N33/577 , G01N33/579
CPC分类号： G01N33/579 , G01N33/56916 , G01N33/577 , Y10S435/81 , Y10S435/879 , Y10S436/815 , Y10S436/821
摘要： The invention relates to a method of detecting gram-negative bacterial endotoxin using antibody capture combined with amoebocyte lysate chromogenic detection. The method is highly sensitive and rapid and may be used for detection of specific endotoxin. In a particular application, picogram levels of Haemophilus influenzae type b endotoxin are detected in plasma taken from previously infected mammals. In another particular application, the method is applied to the detection and diagnosis of disease, through the detection of endotoxin from disease-causing organisms. A specific example is the diagnosis of chancroid through the detection of endotoxin from H. ducreyi.
摘要翻译： PCT No.PCT / US91 / 04864 Sec。 371日期：1993年2月5日 102（e）日期1993年2月5日PCT 1991年7月10日PCT公布。出版物WO92 / 01228 日期1992年1月23日。本发明涉及使用抗体捕获与变形细胞裂解物显色检测结合来检测革兰氏阴性细菌内毒素的方法。该方法灵敏度高，可快速检测特异性内毒素。在特定应用中，从先前感染的哺乳动物的血浆中检测到流感嗜血杆菌b型内毒素的皮克水平。在另一个具体应用中，该方法通过检测来自致病生物体的内毒素来应用于疾病的检测和诊断。一个具体的例子是通过检测杜氏红细菌中的内毒素来诊断黄疸。

44. 发明授权

US08844584B1 Apparatus and method for a pressurized dispenser refill system 有权
标题翻译：加压分配器补充系统的装置和方法
公开(公告)号：US08844584B1
公开(公告)日：2014-09-30
申请号：US13022368
申请日：2011-02-07
申请人： Kevin Haley , Eric J. Hansen , Christopher D. Barr , Eric C. Huffman , Kenneth M. Lenkiewicz , Joseph P. Perry , Justin Benacquisto
发明人： Kevin Haley , Eric J. Hansen , Christopher D. Barr , Eric C. Huffman , Kenneth M. Lenkiewicz , Joseph P. Perry , Justin Benacquisto
IPC分类号： B65B31/00
CPC分类号： B65B31/00 , B65B3/17 , B65B3/26 , B65B31/003 , B65D83/0055 , B65D83/62
摘要： A sustainable system for refilling a pressurized fluid dispenser comprises a container body having a first fluid dispenser that includes a valved opening, a pouch mounted within the container body for storing a fluid composition and fluidly coupled with the valved opening of the container for dispensing the contents of the pouch and a fluid refill system. A pressurized gas can be provided between the pouch and the container body for pressurizing the contents of the pouch. The fluid refill system includes at least one reservoir having a fluid composition therein and a second fluid dispenser having a fitting that is adapted to dispense the fluid composition from the at least one reservoir into the pouch. A controller can be programmed to respond to input signals to position the container with the fluid refill system and to dispense the fluid composition under pressure into the pouch.
摘要翻译：用于再填充加压流体分配器的可持续系统包括具有第一流体分配器的容器体，所述第一流体分配器包括阀门开口，安装在容器体内的袋，用于存储流体组合物并与容器的阀门开口流体连接以分配内容物的袋和液体补充系统。可以在袋和容器主体之间设置加压气体，以加压袋的内容物。流体补充系统包括至少一个其中具有流体组合物的储存器和具有适于将流体组合物从至少一个储存器分配到袋中的配件的第二流体分配器。可以将控制器编程为响应于输入信号以将流体替换系统定位在容器上，并将压力下的流体组合物分配到袋中。

45. 发明申请

US20130239026A1 MULTI-DIMENSIONAL CONTENT DELIVERY MECHANISM 审中-公开
标题翻译：多维内容传送机制
公开(公告)号：US20130239026A1
公开(公告)日：2013-09-12
申请号：US13413653
申请日：2012-03-07
申请人： Mohammed Omar Farooque , Amalachandran Susainathan , Eric J. Hansen , John C. Wyss , Amitava Majumdar , Jeniffer Lewis
发明人： Mohammed Omar Farooque , Amalachandran Susainathan , Eric J. Hansen , John C. Wyss , Amitava Majumdar , Jeniffer Lewis
IPC分类号： G06F3/048
CPC分类号： G06Q30/02 , G06F16/44 , G06Q10/10
摘要： A content delivery mechanism as a single object (also referred to as object bar) in a user interface. The object bar is a dynamic, context sensitive, adaptive multi-dimensional content delivery vehicle. The polymorphic nature of the object bar and the dynamic mechanism of delivering assistance content and controls (e.g., chat, videos, etc.) make it suitable for use in different application and customer scenarios. The object bar can be packed with N icons, in any order for any given context, with each icon designed to denote a specific dimension of information (a specific information type or intent type). The object bar can be docked on any side of the application view port and the user can chose to minimize it. When employed in an assistance environment for assistance content delivery and controls, a set of icons provides 360-degree perspective of the page.
摘要翻译：作为用户界面中的单个对象（也称为对象条）的内容传递机制。对象栏是一种动态的，上下文相关的自适应多维内容传送工具。对象栏的多态性以及提供辅助内容和控制（例如聊天，视频等）的动态机制使其适合于在不同的应用和客户场景中使用。对象栏可以以任何给定上下文的顺序打包N个图标，每个图标旨在表示信息的特定维度（特定信息类型或意图类型）。对象栏可以停靠在应用程序视图端口的任意一侧，用户可以选择将其最小化。在帮助内容交付和控制的辅助环境中工作时，一组图标可以提供页面的360度视角。

46. 发明申请

US20100264165A1 MANUAL SPRAY CLEANER PACKAGE 审中-公开
标题翻译：手动喷雾清洁器包装
公开(公告)号：US20100264165A1
公开(公告)日：2010-10-21
申请号：US12759100
申请日：2010-04-13
申请人： Eric J. Hansen , Christopher D. Barr , Mary Jasch , Romaneerat Nemcek
发明人： Eric J. Hansen , Christopher D. Barr , Mary Jasch , Romaneerat Nemcek
IPC分类号： B65D83/14 , B65B31/00
CPC分类号： B32B15/08 , B65D83/425 , B65D83/62 , C09K3/30 , C11D3/3947 , C11D17/0043 , C11D17/041
摘要： A disinfecting solution package comprising a dispensing container having a body with a closed bottom and an open upper end forming a neck and a dispensing valve mounted in the neck. A flexible pouch is mounted within the container and has an open upper end that is sealed to the dispensing valve. A disinfecting composition containing a disinfecting agent is stored in the flexible pouch. A pressurized gas is between the container body and the flexible pouch to pressurize the disinfecting solution within the flexible pouch.
摘要翻译：一种消毒溶液包装，包括具有封闭底部的主体和形成颈部的开放上端的分配容器和安装在颈部中的分配阀。柔性袋安装在容器内，并且具有密封到分配阀的敞开的上端。含有消毒剂的消毒组合物储存在柔性袋中。加压气体在容器主体和柔性袋之间，以对柔性袋内的消毒溶液加压。

47. 发明授权

US07569683B2 UspA2 nucleic acid of Moraxella catarrhalis 失效
标题翻译：莫斯卡氏杆菌的UspA2核酸
公开(公告)号：US07569683B2
公开(公告)日：2009-08-04
申请号：US12044818
申请日：2008-03-07
申请人： Eric J. Hansen , Christoph Aebi , Leslie D. Cope , Isobel Maciver , Michael J. Fiske , Ross A. Fredenburg
发明人： Eric J. Hansen , Christoph Aebi , Leslie D. Cope , Isobel Maciver , Michael J. Fiske , Ross A. Fredenburg
IPC分类号： C07H21/04
CPC分类号： C07K14/212 , A61K39/00 , C07K16/1217
摘要： The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two proteins and comprises an epitope that is recognized by the MAb 17C7. One or more than one of these species may aggregate to form the very high molecular weight form (i.e. greater than 200 kDa) of the UspA antigen. Compositions and both diagnostic and therapeutic methods for the treatment and study of M. catarrhalis are disclosed.
摘要翻译：本发明公开了两种新型蛋白质UspA1和UspA2及其各自的基因uspA1和uspA2的存在。每个蛋白质包含在两种蛋白质之间保守的区域，并且包含由MAb 17C7识别的表位。这些物质中的一种或多于一种可能聚集形成UspA抗原的非常高分子量形式（即大于200kDa）。公开了组合物以及用于治疗和研究卡他莫拉菌的诊断和治疗方法。

48. 发明申请

US20090126144A1 PROTECTANT APPLICATION 审中-公开
标题翻译：保护申请
公开(公告)号：US20090126144A1
公开(公告)日：2009-05-21
申请号：US12339823
申请日：2008-12-19
申请人： Gary A. Kasper , Eric J. Hansen
发明人： Gary A. Kasper , Eric J. Hansen
IPC分类号： A47L7/00 , B08B3/08
CPC分类号： A47L11/4075 , A47L11/34 , A47L11/4083 , A47L11/4088 , Y10T137/0402
摘要： A portable surface cleaning apparatus has a first tank connected to the housing and with a body of a liquid protectant composition therein, a second tank mounted to the housing with a body of water therein, and a fluid delivery system with an inlet in fluid communication with each of the first and second tanks and an outlet in fluid communication with a spray nozzle for spraying a mixture of the liquid protectant and water onto a surface.
摘要翻译：便携式表面清洁装置具有连接到壳体的第一罐和其中具有液体保护剂组合物的主体，安装在壳体上的第二罐，其中具有水体，以及流体输送系统，其具有与第一和第二储罐中的每一个以及与用于将液体保护剂和水的混合物喷射到表面上的喷嘴流体连通的出口。

49. 发明授权

US07198070B1 Assembling aerosol container packages 有权
标题翻译：组装气溶胶容器包装
公开(公告)号：US07198070B1
公开(公告)日：2007-04-03
申请号：US10711483
申请日：2004-09-21
申请人： Eric J. Hansen , Timothy S. Parker
发明人： Eric J. Hansen , Timothy S. Parker
IPC分类号： B65B1/04
CPC分类号： B65B35/58 , B65B17/02 , B65B57/14
摘要： A process of filling containers includes a passivating the filling equipment immediately prior to filling the containers with an oxidizing composition. Adjacent containers filled with different compositions are oriented relative to each other by marking the containers with a visible indicia representative of a pick up point of a dip tube within the container, rotating the containers relative to each other until the pick up point of each dip tube is positioned is a predetermined relationship to each other and thereafter adhering the containers are to each other in the predetermined relationship.
摘要翻译：填充容器的过程包括在用氧化组合物填充容器之前立即钝化填充设备。填充有不同成分的相邻容器相对于彼此定位，通过用容器中的汲取管的拾取点的可见标记标记容器，使容器相对于彼此旋转直到每个汲取管的拾取点被定位为彼此之间的预定关系，此后以预定关系彼此粘附容器。

50. 发明授权

US6131237A Upright extraction cleaning machine 有权
标题翻译：立式提取清洗机
公开(公告)号：US6131237A
公开(公告)日：2000-10-17
申请号：US133832
申请日：1998-08-13
申请人： Gary A. Kasper , David E. McDowell , Eric J. Hansen
发明人： Gary A. Kasper , David E. McDowell , Eric J. Hansen
IPC分类号： A47L5/30 , A47L5/32 , A47L7/00 , A47L11/30 , A47L11/34 , A47L11/40 , B01F3/08 , C11D3/00 , C11D3/39 , C11D7/32 , C11D11/00 , F16K31/54 , H05B3/00
CPC分类号： A47L5/30 , A47L11/30 , A47L11/34 , A47L11/4044 , A47L11/4083 , A47L11/4088 , A47L5/225 , A47L5/32 , A47L7/0009 , A47L7/0023 , A47L7/0038 , A47L7/0042 , A47L9/0036 , B01F3/088 , C11D11/007 , C11D3/0031 , C11D3/39 , C11D3/3905 , C11D3/3947 , C11D7/3254 , F16K31/54 , H05B3/00 , C11D3/3917
摘要： A portable surface cleaning apparatus comprises a base module for movement along the surface; an upright handle pivotally attached to the base module; a fluid dispensing system including at least one fluid supply tank mounted to the handle or the base module, a dispensing nozzle mounted to the base module for applying a cleaning fluid to a surface to be cleaned, and a heater for heating the fluid to be applied to the surface to be cleaned to a temperature less than boiling; a fluid recovery tank mounted to the handle or the base module for holding recovered fluid; a suction nozzle associated with the base module; a working air conduit extending between the recovery tank and the suction nozzle; and a vacuum source and fluid communication with the recovery tank for generating a flow of working air from the suction nozzle through the working air conduit and through the recovery tank to thereby recovering fluid from the surface to be cleaned through the suction nozzle and working air conduit and into the recovery tank. A method for cleaning a surface in which a fluid cleaning solution is contained in a tank and dispensed on the surface through a nozzle and the cleaning solution is recovered from the surface with suction and deposited into a recovery tank includes, according to the invention, the steps of admixing an oxidizing agent with the cleaning solution, and heating the admixture prior to the step of dispensing the cleaning solution onto the surface to be cleaned.
摘要翻译：便携式表面清洁装置包括用于沿着表面移动的基座模块; 可枢转地连接到基座模块的直立手柄; 流体分配系统，包括安装到手柄或基座模块的至少一个流体供应罐;安装到基座模块的分配喷嘴，用于将清洁流体施加到待清洁的表面;以及加热器，用于加热要施加的流体待表面清洗至低于沸点的温度; 安装到手柄或基座模块上用于保持回收的流体的流体回收罐; 与所述基座模块相关联的吸嘴; 在回收罐和吸嘴之间延伸的工作空气导管; 以及真空源并与回收罐流体连通，用于从吸嘴通过工作空气管道和通过回收罐产生工作空气流，从而通过吸嘴和工作空气管道从要清洁的表面回收流体并进入回收罐。一种用于清洁其中流体清洁溶液容纳在罐中并通过喷嘴分配在表面上的表面的清洁方法，并且从吸附表面回收清洁溶液并将其沉积到回收罐中的方法包括根据本发明，将氧化剂与清洁溶液混合的步骤，以及在将清洁溶液分配到待清洁表面的步骤之前加热混合物。

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