专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

US20070171430A1 SYSTEMS AND METHODS FOR PROVIDING MIRROR TUNNEL MICROPSCOPY 审中-公开
标题翻译：用于提供微波隧道微波的系统和方法
公开(公告)号：US20070171430A1
公开(公告)日：2007-07-26
申请号：US11624601
申请日：2007-01-18
申请人： Guillermo J. Tearney , Brett E. Bouma , Aydogan Ozcan
发明人： Guillermo J. Tearney , Brett E. Bouma , Aydogan Ozcan
IPC分类号： G01B11/02
CPC分类号： G02B27/08 , G01J3/36 , G02B17/006 , G02B21/00 , G02B21/367 , G02B27/46
摘要： Exemplary apparatus and method for obtaining information associated with at least one image of at least one portion of a sample can be provided. For example, at least one first electro-magnetic radiation can be provided from the at least one portion (e.g., using a first electro-magnetic radiation guiding arrangement which is configured to provide). A plurality of spatial frequency bands of the image associated with the first electro-magnetic radiation can be generated. Further, at least one second electro-magnetic radiation which is associated with the spatial frequency bands of the image can be received (e.g., using a second arrangement), and the image can be reconstructed based on the spatial frequency bands.
摘要翻译：可以提供用于获得与样品的至少一部分的至少一个图像相关联的信息的示例性装置和方法。例如，可以从至少一个部分（例如，使用配置为提供的第一电磁辐射引导装置）提供至少一个第一电磁辐射。可以产生与第一电磁辐射相关联的图像的多个空间频带。此外，可以接收与图像的空间频带相关联的至少一个第二电磁辐射（例如，使用第二布置），并且可以基于空间频带重建图像。

42. 发明授权

US06831781B2 Confocal microscopy with multi-spectral encoding and system and apparatus for spectroscopically encoded confocal microscopy 有权
标题翻译：具有多光谱编码的共聚焦显微镜和用于光谱编码的共焦显微镜的系统和装置
公开(公告)号：US06831781B2
公开(公告)日：2004-12-14
申请号：US09999182
申请日：2001-11-29
申请人： Guillermo J. Tearney , Brett E. Bouma , Robert H. Webb , Constantinos Pitris , Millen Shishkov
发明人： Guillermo J. Tearney , Brett E. Bouma , Robert H. Webb , Constantinos Pitris , Millen Shishkov
IPC分类号： G02B2106
CPC分类号： A61B1/00096 , A61B1/00172 , A61B5/0068 , A61B5/0075 , A61B5/0084 , A61B5/415 , A61B5/418 , A61B5/6852 , G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/0291 , G01J3/06 , G01J3/12 , G01J3/14 , G01J3/18 , G01J3/28 , G01J2003/062 , G01J2003/064 , G01J2003/065 , G01J2003/069 , G02B21/0028 , G02B21/0056 , G02B21/0064 , G02B21/0076 , G02B23/2453
摘要： A scanning confocal microscopy system and apparatus, especially useful for endoscopy with a flexible probe which is connected to the end of an optical fiber (9). The probe has a grating (12) and a lens (14) which delivers a beam of multi-spectral light having spectral components which extend in one dimension across a region of an object and which is moved to scan in another dimension. The reflected confocal spectrum is measured to provide an image of the region.
摘要翻译：一种扫描共聚焦显微镜系统和装置，特别适用于连接到光纤端部（9）的柔性探头的内窥镜检查。探针具有光栅（12）和透镜（14），其传送具有光谱分量的多光谱光束，该光谱分量在一个维度上延伸跨越物体的区域并且被移动以在另一维度上扫描。测量反射共焦光谱以提供该区域的图像。

43. 发明授权

US06341036B1 Confocal microscopy with multi-spectral encoding 有权
标题翻译：共聚焦显微镜与多光谱编码
公开(公告)号：US06341036B1
公开(公告)日：2002-01-22
申请号：US09622971
申请日：2000-08-24
申请人： Guillermo J. Tearney , Brett E. Bouma , Robert H. Webb
发明人： Guillermo J. Tearney , Brett E. Bouma , Robert H. Webb
IPC分类号： G02B2100
CPC分类号： G02B21/0064 , A61B5/0062 , A61B5/0066 , A61B5/0068 , A61B5/0075 , A61B5/0084 , A61B5/6852 , G01J3/28 , G02B21/0028 , G02B21/0056 , G02B21/0076 , G02B23/2453
摘要： A scanning confocal microscopy system, especially useful for endoscopy with a flexible probe which is connected to the end of an optical fiber(9). The probe has a grating(12) and a lens(14) which delivers a beam of multi-spectral light having spectral components which extend in one dimension across a region of an object and which is moved to scan in another dimension. The reflected confocal spectrum is measured to provide an image of the region.
摘要翻译：一种扫描共聚焦显微镜系统，特别适用于连接到光纤端部的柔性探头（9）的内窥镜检查。探针具有光栅（12）和透镜（14），其传送具有光谱分量的多光谱光束，该光谱分量在一个维度上延伸跨越物体的区域并且被移动以在另一维度上扫描。测量反射共焦光谱以提供该区域的图像。

44. 发明授权

US09615748B2 Endoscopic biopsy apparatus, system and method 有权
公开(公告)号：US09615748B2
公开(公告)日：2017-04-11
申请号：US12690686
申请日：2010-01-20
申请人： Guillermo J. Tearney , Brett E. Bouma , Dongkyun Kang , Melissa J. Suter
发明人： Guillermo J. Tearney , Brett E. Bouma , Dongkyun Kang , Melissa J. Suter
IPC分类号： A61B6/00 , A61B5/00 , A61B5/02
CPC分类号： A61B5/0066 , A61B5/0068 , A61B5/0075 , A61B5/0086
摘要： Exemplary embodiments of apparatus, method and system for determining a position on or in a biological tissue can be provided. For example, using such exemplary embodiment, it is possible to control the focus of an optical imaging probe. In another exemplary embodiment, it is possible to implement a marking apparatus together with or into an optical imaging probe. According to one exemplary embodiment, it is possible (using one or more arrangements) to receive information associated with at least one image of at least one portion of the biological tissue obtained using an optical imaging technique. Further, it is possible to, based on the information, cause a visible change on or in at least location of the portion(s) using at least one electro-magnetic radiation.

45. 发明授权

US09282931B2 Methods for tissue analysis 有权
标题翻译：组织分析方法
公开(公告)号：US09282931B2
公开(公告)日：2016-03-15
申请号：US13251594
申请日：2011-10-03
申请人： Guillermo J. Tearney , Brett E. Bouma
发明人： Guillermo J. Tearney , Brett E. Bouma
IPC分类号： A61B5/00 , A61B1/00 , A61B1/07 , A61B5/02 , G01N21/49 , A61B1/06
CPC分类号： A61B5/6885 , A61B1/00082 , A61B1/0615 , A61B1/07 , A61B5/0066 , A61B5/0068 , A61B5/0075 , A61B5/0084 , A61B5/02007 , A61B5/7207 , A61B5/7257 , G01N21/49
摘要： The invention relates to methods and systems to optically analyze samples such as tissue based on speckle patterns of microscopic motion, such as Brownian motion.
摘要翻译：本发明涉及基于诸如布朗运动的微观运动的斑纹图案光学分析诸如组织的样品的方法和系统。

46. 发明授权

US08804126B2 Systems, methods and computer-accessible medium which provide microscopic images of at least one anatomical structure at a particular resolution 有权
标题翻译：以特定分辨率提供至少一个解剖结构的微观图像的系统，方法和计算机可访问介质
公开(公告)号：US08804126B2
公开(公告)日：2014-08-12
申请号：US13042230
申请日：2011-03-07
申请人： Guillermo J. Tearney , Brett E. Bouma , Joseph A. Gardecki , Linbo Liu
发明人： Guillermo J. Tearney , Brett E. Bouma , Joseph A. Gardecki , Linbo Liu
IPC分类号： G01B9/02
CPC分类号： A61B5/0066 , A61B5/0044 , A61B5/0075 , A61B5/0084 , G01B9/02091 , G02B6/32
摘要： Exemplary embodiments of systems and methods can be provided which can generate data associated with at least one portion of a sample. For example, at least one first radiation can be forwarded to the portion through at least one optical arrangement. At least one second radiation can be received from the portion which is based on the first radiation. Based on an interaction between the optical arrangement and the first radiation and/or the second radiation, the optical arrangement can have a first transfer function. Further, it is possible to forward at least one third radiation to the portion through such optical arrangement (or through another optical arrangement), and receive at least one fourth radiation from the portion which is based on the third radiation. Based on an interaction between the optical arrangement (or the other optical arrangement) and the third radiation and/or the fourth radiation, the optical arrangement (or the other optical arrangement) can have a second transfer function. The first transfer function can be at least partially different from the second transfer function. The data can be generated based on the second and fourth radiations.
摘要翻译：可以提供可以生成与样品的至少一部分相关联的数据的系统和方法的示例性实施例。例如，可以通过至少一个光学布置将至少一个第一辐射转发到该部分。可以从基于第一辐射的部分接收至少一个第二辐射。基于光学布置和第一辐射和/或第二辐射之间的相互作用，光学装置可以具有第一传递函数。此外，可以通过这种光学装置（或通过另一种光学装置）将至少一个第三辐射转发到该部分，并且从基于第三辐射的部分接收至少一个第四辐射。基于光学布置（或另一个光学布置）和第三辐射和/或第四辐射之间的相互作用，光学布置（或另一个光学布置）可以具有第二传递函数。第一传递函数可以至少部分地不同于第二传递函数。可以基于第二和第四辐射来生成数据。

47. 发明授权

US08150496B2 Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties 有权
标题翻译：通过测量组织光学性质测定动脉粥样硬化斑块类型的方法和装置
公开(公告)号：US08150496B2
公开(公告)日：2012-04-03
申请号：US12188679
申请日：2008-08-08
申请人： Guillermo J. Tearney , Brett E. Bouma
发明人： Guillermo J. Tearney , Brett E. Bouma
IPC分类号： A61B5/05
CPC分类号： G01B9/02014 , A61B1/00165 , A61B5/0066 , A61B5/0084 , G01B9/02007 , G01B9/02072 , G01B9/02083 , G01B9/02088 , G01B9/02091 , G01B2290/70
摘要： Methods for diagnosing vulnerable atherosclerotic plaque using optical coherence tomography to measure tissue optical properties, including backreflectance of heterogeneous layers, such as plaque cap, lipid pool composition and macrophage presence. Methods also include measurement of spatially and temporally dependent reflectance, measurement of multiple wavelength reflectance, low coherence interferometry, polarization and quantification of macrophage content.
摘要翻译：使用光学相干断层扫描来诊断易受伤害的动脉粥样硬化斑块的方法来测量组织光学性质，包括异质层的后向反射，例如斑块盖，脂质池组成和巨噬细胞存在。方法还包括空间和时间依赖反射率的测量，多波长反射率的测量，低相干干涉测量，极化和巨噬细胞含量的定量。

48. 发明授权

US08097864B2 System, method and computer-accessible medium for providing wide-field superresolution microscopy 失效
标题翻译：用于提供广域超分辨率显微镜的系统，方法和计算机可访问介质
公开(公告)号：US08097864B2
公开(公告)日：2012-01-17
申请号：US12693563
申请日：2010-01-26
申请人： Guillermo J. Tearney , Brett E. Bouma , Jing Yuan
发明人： Guillermo J. Tearney , Brett E. Bouma , Jing Yuan
IPC分类号： G01N21/64
CPC分类号： G01N21/6458 , G02B21/0032 , G02B21/0072 , G02B21/0076 , G02B21/16 , G02B27/48
摘要： Exemplary embodiments of apparatus, system, method and computer-accessible medium using which at least one first pulsed electro-magnetic radiation is generated. Such radiation depletes at least one excited state of at least one molecule. Further, it is possible to generate at least one second electro-magnetic radiation based on the first pulsed electro-magnetic radiation(s). For example, the second electro-magnetic radiation(s) can have a pattern with a plurality of spots.
摘要翻译：产生至少一个第一脉冲电磁辐射的装置，系统，方法和计算机可访问介质的示例性实施例。这种辐射消耗至少一种分子的至少一种激发态。此外，可以基于第一脉冲电磁辐射产生至少一个第二电磁辐射。例如，第二电磁辐射可以具有具有多个点的图案。

49. 发明申请

US20100110414A1 SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR TRACKING VESSEL MOTION DURING THREE-DIMENSIONAL CORONARY ARTERY MICROSCOPY 有权
标题翻译：系统，方法和计算机可访问介质在三维冠状动脉微血管中跟踪血管运动
公开(公告)号：US20100110414A1
公开(公告)日：2010-05-06
申请号：US12437392
申请日：2009-05-07
申请人： Christopher Max Colice , Brett E. Bouma , Guillermo J. Tearney , Jinyong Ha , Milen Shishkov
发明人： Christopher Max Colice , Brett E. Bouma , Guillermo J. Tearney , Jinyong Ha , Milen Shishkov
IPC分类号： G01P3/36 , G01P3/00
CPC分类号： A61B5/0084 , A61B5/0062 , A61B5/0066 , A61B5/0097 , A61B5/1076 , A61B5/1114 , A61B5/489 , A61B5/6844 , A61B5/6852 , A61B8/08 , A61B8/0891 , A61B8/12 , A61B8/488 , A61B90/36 , A61B2090/364 , A61B2090/3782 , G01S15/50 , G01S15/60 , G01S15/87 , G01S17/50 , G01S17/87
摘要： Exemplary embodiments of apparatus, method and computer accessible medium can be provided which can facilitate a determination of at least one characteristic of a structure. For example, it is possible to use at least one first arrangement which can be structured to provide at least one first transmitted radiation along a first axis and at least one second transmitted radiation along a second axis. The first and second transmitted radiations can impact the structure and generate respective first and second returned radiation. The first and second axis can be provided at a predetermined angle with respect with one another which is greater than 0. Further, at least one second arrangement can be provided which can be configured to receive data associated with the first and second returned radiations, and determine at least one relative velocity between the structure and the first arrangement along the first and second axes.
摘要翻译：可以提供装置，方法和计算机可访问介质的示例性实施例，其可以有助于确定结构的至少一个特征。例如，可以使用至少一个第一布置，其可被构造成沿着第一轴线提供至少一个第一透射辐射以及沿着第二轴线提供至少一个第二透射辐射。第一和第二透射辐射可以影响结构并产生相应的第一和第二反射辐射。第一和第二轴线可以彼此相对于预定角度提供，该角度大于0.此外，可以提供至少一个第二布置，其可被配置为接收与第一和第二返回辐射有关的数据，以及确定沿着第一和第二轴线的结构和第一布置之间的至少一个相对速度。

50. 发明申请

US20090073439A1 APPARATUS, COMPUTER-ACCESSIBLE MEDIUM AND METHOD FOR MEASURING CHEMICAL AND/OR MOLECULAR COMPOSITIONS OF CORONARY ATHEROSCLEROTIC PLAQUES IN ANATOMICAL STRUCTURES 审中-公开
标题翻译：装置，计算机可接受的介质和测量化学和/或分子结构的冠状动脉造影剂在解剖结构中的方法
公开(公告)号：US20090073439A1
公开(公告)日：2009-03-19
申请号：US12210979
申请日：2008-09-15
申请人： Guillermo J. Tearney , Brett E. Bouma , Jason T. Motz , Joseph A. Gardecki , Alexandra H. Chau
发明人： Guillermo J. Tearney , Brett E. Bouma , Jason T. Motz , Joseph A. Gardecki , Alexandra H. Chau
IPC分类号： G01N21/00 , G02B6/06 , G06G7/48
CPC分类号： A61B5/0075 , A61B5/0084 , A61B5/02007
摘要： Exemplary apparatus and method can be provided for controlling at least one electro-magnetic radiation. For example, it is possible to rotate and/or translate at least one optical waveguide. At least one of the optical waveguide(s) can receive a first radiation at a first wavelength and transmit the first radiation to at least one sample. Such optical waveguide and/or another optical waveguide may receive a second radiation at a second wavelength that is different from the first wavelength. For example, the second radiation may be produced based on an inelastic scattering of the first radiation. In addition, exemplary apparatus and method can be provided which can also be used to receive data associated with the second radiation, determine at least one characteristic of the at least one sample based on the data, and generate the image and/or the map of a portion of the arterial sample based on the at least one characteristic. Further, exemplary computer-accessible medium can be provided which includes a software arrangement thereon. When a processing arrangement executes the software arrangement, the processing arrangement is configured to modify at least one characteristic of an arrangement using certain procedures. These exemplary procedures include simulating at least one electro-magnetic radiation provided into and out of the arrangement, simulating an inelastic scattering radiation from at least one simulated sample, receiving the simulated inelastic scattering radiation into and out of the simulated arrangement, and determining a simulated characteristic of the simulated arrangement as a function of the simulated inelastic scattering radiation.
摘要翻译：可以提供示例性的装置和方法来控制至少一个电磁辐射。例如，可以旋转和/或平移至少一个光波导。至少一个光波导可以接收第一波长的第一辐射并将第一辐射传输到至少一个样本。这种光波导和/或另一光波导可以接收与第一波长不同的第二波长的第二辐射。例如，可以基于第一辐射的非弹性散射来产生第二辐射。此外，可以提供示例性的装置和方法，其还可以用于接收与第二辐射相关联的数据，基于数据确定至少一个样本的至少一个特性，并且生成图像和/或基于至少一个特征的动脉样本的一部分。此外，可以提供示例性的计算机可访问介质，其中包括其上的软件布置。当处理装置执行软件装置时，处理装置被配置为使用某些程序来修改装置的至少一个特性。这些示例性程序包括模拟提供入和排出的至少一个电磁辐射，模拟来自至少一个模拟样本的非弹性散射辐射，将模拟的非弹性散射辐射接收到模拟装置中和从模拟装置中取出，以及确定模拟作为模拟非弹性散射辐射的函数的模拟布置的特征。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式