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41. 发明申请

US20070143096A1 Data backup system including a data protection component 有权
标题翻译：数据备份系统包括数据保护组件
公开(公告)号：US20070143096A1
公开(公告)日：2007-06-21
申请号：US11605770
申请日：2006-11-28
申请人： Jeffrey Brunet , Ian Collins , Yousuf Chowdhary , Eric Li , Alex Lemelev
发明人： Jeffrey Brunet , Ian Collins , Yousuf Chowdhary , Eric Li , Alex Lemelev
IPC分类号： G06F9/455
CPC分类号： G06F3/0605 , G06F3/0632 , G06F3/065 , G06F3/0676 , G06F3/0677 , G06F3/0679 , G06F11/1451 , G06F11/1456 , G06F11/1461
摘要： A data backup system is provided for backing up data files from a data source and for securing those data files against accidental modification or deletion. The system comprises storage and a data protection component that includes an application programming interface defining a command set. The system can also comprise a backup application that is configured to use the commands of the command set. The data protection component allows applications that use the commands of the command set, such as the backup application, to access the storage of the system. The data protection component prevents operating systems and applications that do not use the commands of the command set from accessing the storage. The data protection function of the data protection component can optionally be disabled to allow open access to the storage.
摘要翻译：提供数据备份系统，用于从数据源备份数据文件，并保护这些数据文件免受意外修改或删除。该系统包括存储和数据保护组件，其包括定义命令集的应用程序编程接口。系统还可以包括配置为使用命令集的命令的备份应用程序。数据保护组件允许使用命令集的命令（如备份应用程序）访问系统存储的应用程序。数据保护组件防止不使用命令集命令的操作系统和应用程序访问存储。可以选择禁用数据保护组件的数据保护功能，以允许对存储器的打开访问。

42. 发明申请

US20070083354A1 Emulation component for data backup applications 有权
标题翻译：用于数据备份应用程序的仿真组件
公开(公告)号：US20070083354A1
公开(公告)日：2007-04-12
申请号：US11492380
申请日：2006-07-24
申请人： Ian Collins , Eric Li , Yousuf Chowdhary , Jeffrey Brunet
发明人： Ian Collins , Eric Li , Yousuf Chowdhary , Jeffrey Brunet
IPC分类号： G06F9/455
CPC分类号： G06F3/065 , G06F3/0605 , G06F3/0632 , G06F3/0676 , G06F3/0677 , G06F11/1451 , G06F11/1458 , G06F11/1461
摘要： An emulation component for a data backup system is provided. The emulation component represents a storage device, such as a flash memory device or a partition of a disk drive, as if it were an auto-launch device, that will trigger applications to execute automatically. Accordingly, other computing systems, such as personal computers, interact with the storage device, through the emulation component, as if the storage device were the auto-launch device. Because the emulation component makes this representation, merely connecting the emulation component between the storage device and the computing system can cause a backup application stored on the storage device to automatically execute on the computing system. A data backup appliance including an emulation component and a storage device is also provided. The backup system can also include an interface for connecting another removable device, such as a disk drive, for storing backup content from the data source.
摘要翻译：提供了一种用于数据备份系统的仿真组件。仿真组件表示存储设备，例如闪存设备或磁盘驱动器的分区，就像它是自动启动设备一样，将触发应用程序自动执行。因此，诸如个人计算机的其他计算系统通过仿真组件与存储设备交互，就像存储设备是自动发射设备一样。由于仿真组件做出这种表示，只需将存储设备和计算系统之间的仿真组件连接起来，就能够使存储在存储设备上的备份应用程序在计算系统上自动执行。还提供了包括仿真组件和存储设备的数据备份设备。备份系统还可以包括用于连接另一个可移动设备（如磁盘驱动器）的接口，用于从数据源存储备份内容。

43. 发明申请

US20060135570A1 Cyclic sulfamides for inhibiton of gamma-secretase 失效
标题翻译：用于抑制γ-分泌酶的环状磺酰胺
公开(公告)号：US20060135570A1
公开(公告)日：2006-06-22
申请号：US10533272
申请日：2003-10-31
申请人： Ian Collins , Joanne Hannam , Timothy Harrison , Andrew Madin , Mark Ridgill
发明人： Ian Collins , Joanne Hannam , Timothy Harrison , Andrew Madin , Mark Ridgill
IPC分类号： A61K31/433 , C07D271/12
CPC分类号： C07D417/10
摘要： Compounds of formula I: inhibit the processing of AP by gamma-secretase, and hence are useful for treatment or prevention of Alzheimer's disease.
摘要翻译：式I化合物：通过γ-分泌酶抑制AP的加工，因此可用于治疗或预防阿尔茨海默氏病。

44. 发明申请

US20050149368A1 Mobile care engine system 失效
标题翻译：移动护理引擎系统
公开(公告)号：US20050149368A1
公开(公告)日：2005-07-07
申请号：US10889693
申请日：2004-07-12
申请人： Jeffrey Brunet , Ian Collins , Yousuf Chowdhary , Stephen Kim
发明人： Jeffrey Brunet , Ian Collins , Yousuf Chowdhary , Stephen Kim
IPC分类号： H04W24/00 , H04Q7/20
CPC分类号： H04W24/00 , G06Q10/063 , G06Q10/20
摘要： A mobile care engine system is provided for delivering customer care to mobile devices, comprising. The mobile care engine system compares profile data from a mobile device with reference data and highlights any inconsistencies between the data, so that the device can be optimized. The inconsistencies are preferably determined using rule-based processing, and are automatically highlighted on the device display itself, or on a display of a customer service representative interface. Optionally, the system allows for corrective patches or settings to be sent to the device.
摘要翻译：提供了一种移动护理引擎系统，用于向移动设备提供客户服务，包括。移动护理引擎系统将来自移动设备的简档数据与参考数据进行比较，并突出显示数据之间的任何不一致，使得可以优化设备。不一致性优选地使用基于规则的处理来确定，并且在设备显示器本身上或在客户服务代表性界面的显示器上自动突出显示。可选地，系统允许将校正补丁或设置发送到设备。

45. 发明申请

US20050143369A1 Gamma-secretase inhibitors 失效
标题翻译： γ-分泌酶抑制剂
公开(公告)号：US20050143369A1
公开(公告)日：2005-06-30
申请号：US10982586
申请日：2004-11-05
申请人： Jose Castro Pineiro , Ian Collins , Timothy Harrison
发明人： Jose Castro Pineiro , Ian Collins , Timothy Harrison
IPC分类号： C07D417/04 , A61K31/554 , A61K31/54
CPC分类号： C07D417/04
摘要： Compounds of formula I: inhibit gamma-secretase and hence find use in treatment of Alzheimer's disease.
摘要翻译：式I化合物：抑制γ-分泌酶，因此可用于治疗阿尔茨海默氏病。

46. 发明授权

US3943141A Tetrazolyl containing naphthyridine 3-carboxamides 失效
标题翻译：含有四氮唑的三氮杂萘-3-甲酰胺
公开(公告)号：US3943141A
公开(公告)日：1976-03-09
申请号：US455072
申请日：1974-03-27
申请人： Gwynn Pennant Ellis , Ian Collins , David Martin Waters , David Edmund Bays
发明人： Gwynn Pennant Ellis , Ian Collins , David Martin Waters , David Edmund Bays
IPC分类号： C07D471/04 , C07D401/14
CPC分类号： C07D471/04 , Y10S514/826 , Y10S514/861
摘要： Compounds of the general formulae I and II and pharmaceutically acceptable salts thereof: ##SPC1##In which:R.sub.1 represents a hydrogen atom, a halogen atom, an alkenyl or alkyl group; or a group OR.sub.3 or NR.sub.3 R.sub.4 where R.sub.3 and R.sub.4 which may be the same or different and may represent a hydrogen atom, or an alkenyl group, or an alkyl group which alkyl group may optionally be substituted by one or more hydroxy, alkoxy, acyloxy, aryl, amino, alkylamino, dialkylamino, diaralkylamino or alkylaralkylamino groups; or R.sub.3 and R.sub.4 together with the nitrogen atom form a 5 or 6 membered heterocyclic ring that may optionally contain other hetero atoms.R.sub.2 has the same meanings as R.sub.3.The compounds have utility for the treatment of conditions in which combination of an antigen with a reaginic antibody is primarily responsible.
摘要翻译：通式I和II的化合物及其药学上可接受的盐：

47. 发明授权

US09541547B2 Fusion antibodies 有权
标题翻译：融合抗体
公开(公告)号：US09541547B2
公开(公告)日：2017-01-10
申请号：US12720108
申请日：2010-03-09
申请人： Gregory T. Bleck , Dona York , Ian Collins
发明人： Gregory T. Bleck , Dona York , Ian Collins
IPC分类号： C07K16/00 , G01N33/53 , A61K39/00
CPC分类号： G01N33/53 , A61K2039/505 , C07K16/00 , C07K2317/31 , C07K2319/00
摘要： The present invention provides novel antibodies. In particular, the present invention provides fusion antibodies comprising antibody heavy and light chain fusions. The present invention further provides multivalent antibodies comprising multiple fusion antibody chains. The present invention further provides methods of generating splice resistant antibody genes.
摘要翻译：本发明提供新型抗体。特别地，本发明提供了包含抗体重链和轻链融合物的融合抗体。本发明还提供了包含多个融合抗体链的多价抗体。本发明还提供了产生抗拼接抗体基因的方法。

48. 发明授权

US09519714B2 Presenting list previews among search results 有权
标题翻译：在搜索结果中列出列表预览
公开(公告)号：US09519714B2
公开(公告)日：2016-12-13
申请号：US12976422
申请日：2010-12-22
申请人： Olga Iosifovna Gurevich , Valerie Rose Nygaard , William Alan Fitzgerald , Jingwen Lu , Toby Takeo Sterrett , Ian Collins
发明人： Olga Iosifovna Gurevich , Valerie Rose Nygaard , William Alan Fitzgerald , Jingwen Lu , Toby Takeo Sterrett , Ian Collins
IPC分类号： G06F3/048 , G06F17/30
CPC分类号： G06F17/30864 , G06F17/30991
摘要： Systems, methods, and computer storage media having computer-executable instructions embodied thereon that facilitates the presentation of list previews among search results are provided. Upon referencing a user query that indicates a user intent to view a list, a search result within a search results page is presented that includes a list preview. Such a list preview includes at least a portion of a list within a webpage that corresponds with the search results.
摘要翻译：提供了具有便于在搜索结果之间呈现列表预览的其上体现的计算机可执行指令的系统，方法和计算机存储介质。在引用指示用户意图查看列表的用户查询时，呈现包括列表预览的搜索结果页面内的搜索结果。这样的列表预览包括与搜索结果相对应的网页内的列表的至少一部分。

49. 发明授权

US08691806B2 Pyrazole derivatives as protein kinase modulators 失效
标题翻译：吡唑衍生物作为蛋白激酶调节剂
公开(公告)号：US08691806B2
公开(公告)日：2014-04-08
申请号：US13536174
申请日：2012-06-28
申请人： Valerio Berdini , Gordon Saxty , Marinus Leendert Verdonk , Steven John Woodhead , Paul Graham Wyatt , Robert George Boyle , Hannah Fiona Sore , David Winter Walker , Ian Collins , Robert Downham , Robin Arthur Ellis Carr
发明人： Valerio Berdini , Gordon Saxty , Marinus Leendert Verdonk , Steven John Woodhead , Paul Graham Wyatt , Robert George Boyle , Hannah Fiona Sore , David Winter Walker , Ian Collins , Robert Downham , Robin Arthur Ellis Carr
IPC分类号： A61K31/397 , C07D231/12
CPC分类号： A61K31/415 , A61K9/0019 , A61K9/20 , A61K9/48 , A61K31/4155 , A61K31/4178 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D231/12 , C07D401/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/04 , C07D413/10
摘要： The invention provides compounds of the formula (I) having protein kinase B inhibiting activity: Also provided are pharmaceutical compositions containing the compounds, methods for preparing the compounds and their use as anticancer agents.
摘要翻译：本发明提供具有蛋白激酶B抑制活性的式（I）化合物：还提供含有化合物的药物组合物，制备化合物的方法及其作为抗癌剂的用途。

50. 发明授权

US08618121B2 9H-pyrimido[4,5-B]indoles, 9H-pyrido[4',3':4,5]pyrrolo[2,3-D]pyridines, and 9H 1,3,6,9 tetraaza-fluorenes as CHK1 kinase function inhibitors 有权
标题翻译： 9H-嘧啶并[4,5-B]吲哚，9H-吡啶并[4'，3'：4,5]吡咯并[2,3-D]吡啶，和9H 1,3,6,9四氮杂芴作为CHK1 激酶功能抑制剂
公开(公告)号：US08618121B2
公开(公告)日：2013-12-31
申请号：US12665961
申请日：2008-07-01
申请人： Ian Collins , John Charles Reader , Suki Klair , Jane Scanlon , Glynn Addison , Michael Cherry
发明人： Ian Collins , John Charles Reader , Suki Klair , Jane Scanlon , Glynn Addison , Michael Cherry
IPC分类号： A01N43/54 , A61K31/505 , C07D239/00 , C07D471/00 , C07D487/00 , C07D491/00
CPC分类号： C07D471/14 , C07D487/04 , C07D487/14
摘要： The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain tricyclic compounds (referred to herein as TC compounds), and especially certain 9H-pyrimido[4,5-b]indole, 9H-pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyridine, and 9H-1,3,6,9-tetraaza-fluorene compounds, which, inter alia, inhibit Checkpoint Kinase 1 (CHK1) kinase function. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit CHK1 kinase function, and in the treatment of diseases and conditions that are mediated by CHK1, that are ameliorated by the inhibition of CHK1 kinase function, etc., including proliferative conditions such as cancer, etc., optionally in combination with another agent, for example, (a) a DNA topoisomerase I or II inhibitor; (b) a DNA damaging agent; (c) an antimetabolite or TS inhibitor; (d) a microtubule targeted agent; and (e) ionising radiation.
摘要翻译：本发明一般涉及治疗化合物领域，更具体地涉及某些三环化合物（本文称为TC化合物），特别是某些9H-嘧啶并[4,5-b]吲哚，9H-吡啶并[4' 3'：4,5]吡咯并[2,3-d]吡啶和9 H-1,3,6,9-四氮杂芴化合物，其特别地抑制检测点激酶1（CHK1）激酶功能。本发明还涉及包含这些化合物的药物组合物，以及这些化合物和组合物在体外和体内的用途，以抑制CHK1激酶功能，以及治疗由CHK1介导的疾病和病症，即通过抑制CHK1激酶功能等改善，包括增殖条件如癌症等，任选地与另一种试剂组合，例如（a）DNA拓扑异构酶I或II抑制剂; （b）DNA损伤剂; （c）抗代谢物或TS抑制剂; （d）微管靶向剂; 和（e）电离辐射。

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