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41. 发明授权

US07655037B2 Combination barb restraint and stent attachment deployment mechanism 有权
标题翻译：组合倒钩约束和支架附件展开机构
公开(公告)号：US07655037B2
公开(公告)日：2010-02-02
申请号：US12104727
申请日：2008-04-17
申请人： James A. Fleming, III , David C. Majercak
发明人： James A. Fleming, III , David C. Majercak
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2002/8483 , A61F2220/0066 , A61F2220/0075 , A61F2250/0039
摘要： An aneurysmal repair system that utilizes a modified apex and delivery device is designed for accurate endoprosthesis delivery and deployment. The modified apex utilizes segments that overlap and hold one another down as well as the fixation barbs attached thereto. The delivery device holds or secures at least one section of the apex and may be easily released by retraction of a hold down member.
摘要翻译：使用改良的顶点和输送装置的动脉瘤修复系统被设计用于精确的内置假体递送和部署。修改的顶点使用重叠并相互保持的部分以及附着于其上的固定倒钩。输送装置保持或固定顶点的至少一个部分，并且可以通过缩回构件容易地释放。

42. 发明授权

US07527632B2 Modified delivery device for coated medical devices 有权
标题翻译：用于涂层医疗器械的改性递送装置
公开(公告)号：US07527632B2
公开(公告)日：2009-05-05
申请号：US10403195
申请日：2003-03-31
申请人： Michael J. Houghton , David C. Majercak
发明人： Michael J. Houghton , David C. Majercak
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2002/9665
摘要： Medical devices, and in particular implantable medical devices, including self-expanding stents, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment.
摘要翻译：医疗装置，特别是包括自扩张支架在内的植入式医疗装置可以被涂覆以最小化或基本上消除生物体对引入生物体的医疗装置的反应。可以修改用于递送可植入医疗装置的装置，以减少在展开期间损害可植入医疗装置的可能性。

43. 发明授权

US07306617B2 Spiral centering catheter 有权
标题翻译：螺旋定心导管
公开(公告)号：US07306617B2
公开(公告)日：2007-12-11
申请号：US10973583
申请日：2004-10-26
申请人： David C. Majercak
发明人： David C. Majercak
IPC分类号： A61M29/00
CPC分类号： A61M25/0069 , A61F2/958 , A61M25/0043 , A61M2025/1047
摘要： A catheter with proximal and distal ends having a spiral centering device attached near the catheter distal end. The spiral centering device has at least one spiral strut having a proximal end and a distal end. The spiral centering device resiliently tends to center the distal end portion of the catheter, steering the catheter away from the vessel wall during insertion through the vasculature and toward the treatment site. The spiral centering catheter may facilitate access to tortuous anatomy by preventing the distal catheter tip from catching on irregularities in the lumenal surface. If a stent is provided on the catheter, the spiral centering catheter may also facilitate uniform stent expansion by stabilizing the catheter during stent deployment.
摘要翻译：具有近端和远端的导管具有附接在导管远端附近的螺旋定心装置。螺旋定心装置具有至少一个具有近端和远端的螺旋支柱。螺旋定心装置弹性地倾向于使导管的远端部分居中，在插入通过脉管系统并朝向治疗部位时将导管转向血管壁。螺旋定心导管可以通过防止远侧导管尖端捕获内腔表面的不规则性来促进进入曲折的解剖结构。如果在导管上设置支架，则螺旋定心导管还可以通过在支架展开期间稳定导管来促进均匀的支架扩张。

44. 发明申请

US20070173929A1 Percutaneous endoprosthesis using suprarenal fixation and barbed anchors 有权
标题翻译：经皮内置假体使用肾上固定和棘刺锚
公开(公告)号：US20070173929A1
公开(公告)日：2007-07-26
申请号：US11338281
申请日：2006-01-24
申请人： Donald D. Boucher , Michael Dugery , Kirk L. Johnson , Isaac John Khan , David C. Majercak , Scott Lyle Rush
发明人： Donald D. Boucher , Michael Dugery , Kirk L. Johnson , Isaac John Khan , David C. Majercak , Scott Lyle Rush
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/07 , A61F2/89 , A61F2002/061 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/8483
摘要： An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.
摘要翻译：一种使用肾上固定治疗腹主动脉瘤的假体内装置。支架环使用在硝基酚膨胀过程中投射的自发光倒钩锚固在肾脏以上的区域。缝合线从支架环延伸到肾脏以下的区域到包括非扭结框架上的镍钛诺织物的分叉主干部分。分叉的躯干在髂动脉附近密封，并且包括具有自我扩张保留支柱的髂骨支架，用于非创伤性髂骨假肢的保持。具有保留突起和倒钩的肾上固定和可折叠细胞，其仅在镍钛诺膨胀过程中发光，有助于降低用于经皮输送的装置轮廓和护套，并可提供重新捕获锚固装置。

45. 发明授权

US06761731B2 Balloon-stent interaction to help reduce foreshortening 有权
标题翻译：气球支架相互作用有助于减少缩短
公开(公告)号：US06761731B2
公开(公告)日：2004-07-13
申请号：US10185504
申请日：2002-06-28
申请人： David C. Majercak
发明人： David C. Majercak
IPC分类号： A61F206
CPC分类号： A61F2/915 , A61F2/91 , A61F2/958 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2230/0013
摘要： The present design envisions a flexible connecting link used in conjunction with in-phase and half-phase circumferential sets of strut members. By increasing the total length and diagonality of the undulating connecting links, the present design is a stent that provides increased flexibility during delivery and enhanced conformability to the shape of a curved artery when the stent is deployed into a curved vessel such as a tortuous coronary artery. Also, unique balloon-stent interactions are described.
摘要翻译：本设计设计了一种与同相和半相圆周组合的支柱构件一起使用的柔性连接链节。通过增加起伏的连接链节的总长度和对角线，本设计是一种支架，其在输送期间提供增加的灵活性，并且当支架部署到诸如曲折冠状动脉的弯曲容器时对弯曲动脉的形状具有增强的适应性。此外，描述了独特的球囊支架相互作用。

46. 发明申请

US20120059452A1 PERCUTANEOUS ENDOPROSTHESIS USING SUPRARENAL FIXATION AND BARBED ANCHORS 有权
标题翻译：使用SUPRARENAL FIXATION和BARBED ANCHORS进行的PERCUTANEOUS ENDOPROSTHESISIS
公开(公告)号：US20120059452A1
公开(公告)日：2012-03-08
申请号：US13295213
申请日：2011-11-14
申请人： Donald D. Boucher , Michael Dugery , Kirk L. Johnson , Issac John Khan , David C. Majercak , Scott Lyle Rush
发明人： Donald D. Boucher , Michael Dugery , Kirk L. Johnson , Issac John Khan , David C. Majercak , Scott Lyle Rush
IPC分类号： A61F2/82
CPC分类号： A61F2/856 , A61F2/07 , A61F2/89 , A61F2002/061 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/8483
摘要： An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.
摘要翻译：一种使用肾上固定治疗腹主动脉瘤的假体内装置。支架环使用在硝基酚膨胀过程中投射的自发光倒钩锚固在肾脏以上的区域。缝合线从支架环延伸到肾脏以下的区域到包括非扭结框架上的镍钛诺织物的分叉主干部分。分叉的躯干在髂动脉附近密封，并且包括具有自我扩张保留支柱的髂骨支架，用于非创伤性髂骨假肢的保持。具有保留突起和倒钩的肾上固定和可折叠细胞，其仅在镍钛诺膨胀过程中发光，有助于降低用于经皮输送的装置轮廓和护套，并可提供重新捕获锚固装置。

47. 发明申请

US20100057187A1 INTRAVASCULAR STENT HAVING IMRPROVED DESIGN FOR LOADING AND DEPLOYING 审中-公开
标题翻译：具有加载和分配的IMRPROVED设计的血管内支架
公开(公告)号：US20100057187A1
公开(公告)日：2010-03-04
申请号：US12198150
申请日：2008-08-26
申请人： Salvatore G. Caldarise , David C. Majercak
发明人： Salvatore G. Caldarise , David C. Majercak
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2002/91575 , A61F2002/91591 , A61F2210/0076 , A61F2230/0054 , A61F2250/0036
摘要： A stent may be inserted into a vessel in order to open and then maintain the patency of the vessel. The stent has a strut design that increases the overall fatigue resistance of the stent. Each strut is tapered to better distribute strain and thus increase fatigue resistance. In addition, some of the struts may comprise protrusions to increase the pushability of the stent during loading into a delivery device.
摘要翻译：可以将支架插入容器中以便打开并且然后维持血管的通畅。支架具有支柱设计，可增加支架的整体抗疲劳性能。每个支柱是锥形的，以更好地分布应变，从而增加抗疲劳性。此外，一些支柱可以包括突起以增加在装载到输送装置中时支架的推动性。

48. 发明申请

US20090264992A1 COMBINATION BARB RESTRAINT AND STENT ATTACHMENT DEPLOYMENT MECHANISM 有权
标题翻译：组合杆限制和固定附件部署机制
公开(公告)号：US20090264992A1
公开(公告)日：2009-10-22
申请号：US12104727
申请日：2008-04-17
申请人： James A. Fleming, III , David C. Majercak
发明人： James A. Fleming, III , David C. Majercak
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2002/8483 , A61F2220/0066 , A61F2220/0075 , A61F2250/0039
摘要： An aneurysmal repair system that utilizes a modified apex and delivery device is designed for accurate endoprosthesis delivery and deployment. The modified apex utilizes segments that overlap and hold one another down as well as the fixation barbs attached thereto. The delivery device holds or secures at least one section of the apex and may be easily released by retraction of a hold down member.
摘要翻译：使用改良的顶点和输送装置的动脉瘤修复系统被设计用于精确的内置假体递送和部署。修改的顶点使用重叠并相互保持的部分以及附着于其上的固定倒钩。输送装置保持或固定顶点的至少一个部分，并且可以通过缩回构件容易地释放。

49. 发明授权

US06190403B1 Low profile radiopaque stent with increased longitudinal flexibility and radial rigidity 有权
标题翻译：低轮廓不透射线支架具有增加的纵向柔性和径向刚度
公开(公告)号：US06190403B1
公开(公告)日：2001-02-20
申请号：US09192101
申请日：1998-11-13
申请人： Robert E. Fischell , David R. Fischell , David C. Majercak
发明人： Robert E. Fischell , David R. Fischell , David C. Majercak
IPC分类号： A61F206
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91541 , A61F2002/91558 , A61F2250/0029
摘要： Disclosed is a comparatively thick-walled vascular stent comprising sets of strut members connected by flexible, longitudinally extending links. This design utilizes flexible links with a variety of different shapes. Adjacent flexible links around the circumference of the stent are designed to nest one into the other, allowing the stent to be both thick-walled and to crimp down without overlap onto a low profile balloon. The flexible links are attached to the sets of strut members not at the center like the “S” links of prior art stents, but off center near the end of the curved strut portion of each set of strut members. This off center attachment point allows for a more flexible link without increasing the cell size of the expanded stent. Small cell size is desirable to limit plaque prolapse into the lumen of the expanded stent and to increase the stent's radial rigidity. The relatively thin strut width with thick wall allows the flexible links to easily lengthen and shorten during stent delivery into the body while still providing each flexible link with a considerable degree of radial strength.
摘要翻译：公开了一种相对厚壁的血管支架，其包括通过柔性的纵向延伸的连杆连接的支柱构件组。这种设计利用各种不同形状的灵活链接。围绕支架圆周的相邻的柔性连接件被设计成将一个嵌入到另一个中，使得支架既可以是厚壁的，也可以无重叠地卷曲到低轮廓气球上。如现有技术支架的“S”链节，柔性连杆附接到不在中心的支柱构件组，但是在每组支柱构件的弯曲支柱部分的端部附近偏离中心。该中心附着点允许更灵活的连接，而不增加扩张的支架的电池尺寸。需要小细胞尺寸以限制斑块脱垂进入扩张的支架的内腔并增加支架的径向刚度。具有厚壁的相对薄的支柱宽度允许柔性连接件在支架输送到体内时容易地延长和缩短，同时仍然提供相当程度的径向强度的每个柔性连杆。

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