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41. 发明授权

US08108608B2 Systems and methods of maintaining freshness of a cached object based on demand and expiration time 有权
标题翻译：根据需求和到期时间来保持缓存对象的新鲜度的系统和方法
公开(公告)号：US08108608B2
公开(公告)日：2012-01-31
申请号：US12020649
申请日：2008-01-28
申请人： Prakash Khemani , Prabakar Sundarrajan , Lakshmi Kumar , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravanakumar Annamalaisami
发明人： Prakash Khemani , Prabakar Sundarrajan , Lakshmi Kumar , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravanakumar Annamalaisami
IPC分类号： G06F12/00
CPC分类号： H04L63/0485 , H04L63/166 , H04L63/168 , H04L67/2842
摘要： A device that implements a method for performing integrated caching in a data communication network. The device is configured to receive a packet from a client over the data communication network, wherein the packet includes a request for an object. At the operating system/kernel level of the device, one or more of decryption processing of the packet, authentication and/or authorization of the client, and decompression of the request occurs prior to and integrated with caching operations. The caching operations include determining if the object resides within a cache, serving the request from the cache in response to a determination that the object is stored within the cache, and sending the request to a server in response to a determination that the object is not stored within the cache.
摘要翻译：实现在数据通信网络中执行集成缓存的方法的设备。该设备被配置为通过数据通信网络从客户端接收分组，其中分组包括对对象的请求。在设备的操作系统/内核级别，分组的解密处理，客户端的认证和/或授权以及请求的解压缩中的一个或多个发生在高速缓存操作之前并且与缓存操作相结合。高速缓存操作包括确定对象是否驻留在高速缓存中，响应于确定对象被存储在高速缓存中而从高速缓存提供请求，以及响应于对象不是的确定将请求发送到服务器存储在缓存中。

42. 发明授权

US07849270B2 System and method for performing entity tag and cache control of a dynamically generated object not identified as cacheable in a network 有权
公开(公告)号：US07849270B2
公开(公告)日：2010-12-07
申请号：US12838171
申请日：2010-07-16
申请人： Prabakar Sundarrajan , Prakash Khemani , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravana Annamalaisami , Bharath Bhushan K R , Anil Kumar
发明人： Prabakar Sundarrajan , Prakash Khemani , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravana Annamalaisami , Bharath Bhushan K R , Anil Kumar
IPC分类号： G06F12/08
CPC分类号： H04L67/2852 , H04L69/329
摘要： The present invention is directed towards a method and system for modifying by a cache responses from a server that do not identify a dynamically generated object as cacheable to identify the dynamically generated object to a client as cacheable in the response. In some embodiments, such as an embodiment handling HTTP requests and responses for objects, the techniques of the present invention insert an entity tag, or “etag” into the response to provide cache control for objects provided without entity tags and/or cache control information from an originating server. This technique of the present invention provides an increase in cache hit rates by inserting information, such as entity tag and cache control information for an object, in a response to a client to enable the cache to check for a hit in a subsequent request.

43. 发明授权

US08572721B2 Methods and systems for routing packets in a VPN-client-to-VPN-client connection via an SSL/VPN network appliance 有权
标题翻译：通过SSL / VPN网络设备在VPN客户端到VPN客户端连接中路由数据包的方法和系统
公开(公告)号：US08572721B2
公开(公告)日：2013-10-29
申请号：US11462174
申请日：2006-08-03
申请人： Arkesh Kumar , James Harris , Ajay Soni
发明人： Arkesh Kumar , James Harris , Ajay Soni
IPC分类号： H04L29/06
CPC分类号： H04L63/0272 , H04L12/4641 , H04L63/166
摘要： In a method and system for routing packets between clients, a packet is received from a first client connected to a secure sockets layer virtual private network (an SSL/VPN) network appliance. An identification is made, responsive to an inspection of the received packet, of i) a type of connection required for transmission of the received packet to a destination address identified by the received packet and ii) a second client connected via an SSL/VPN connection to the SSL/VPN network appliance and associated with the identified destination address. A request is made for establishment by the second client of a connection of the identified type within the SSL/VPN connection. The received packet is transmitted to the second client via the established connection of the identified type.
摘要翻译：在用于在客户端之间路由分组的方法和系统中，从连接到安全套接层层虚拟专用网（SSL / VPN）网络设备的第一客户端接收分组。响应于所接收的分组的检查，进行识别i）将接收的分组传输到由接收分组识别的目的地地址所需的连接类型，以及ii）经由SSL / VPN连接连接的第二客户端到SSL / VPN网络设备并与所识别的目的地址相关联。请求由第二客户端建立SSL / VPN连接中识别类型的连接。所接收的分组经由所识别类型的建立的连接被发送到第二客户端。

44. 发明授权

US08495305B2 Method and device for performing caching of dynamically generated objects in a data communication network 有权
标题翻译：用于在数据通信网络中执行动态生成的对象的缓存的方法和设备
公开(公告)号：US08495305B2
公开(公告)日：2013-07-23
申请号：US11324131
申请日：2005-12-30
申请人： Prabakar Sundarrajan , Prakash Khemani , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravana Annamalaisami , Bharath Bhushan K.R. , Anil Kumar
发明人： Prabakar Sundarrajan , Prakash Khemani , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravana Annamalaisami , Bharath Bhushan K.R. , Anil Kumar
IPC分类号： G06F12/00
CPC分类号： H04L67/42 , G06F17/30902
摘要： A method for maintaining a cache of dynamically generated objects. The method includes storing in the cache dynamically generated objects previously served from an originating server to a client. A communication between the client and server is intercepted by the cache. The cache parses the communication to identify an object determinant and to determine whether the object determinant indicates whether a change has occurred or will occur in an object at the originating server. The cache marks the object stored in the cache as invalid if the object determinant so indicates. If the object has been marked as invalid, the cache retrieves the object from the originating server.
摘要翻译：一种用于维护动态生成的对象的缓存的方法。该方法包括将先前从始发服务器提供的动态生成的对象存储到缓存器中。客户端和服务器之间的通信被缓存拦截。高速缓存解析通信以识别对象行列式，并且确定对象行列式是否指示发生服务器上的对象是否已发生或将发生更改。如果对象行列式指示，高速缓存将存储在缓存中的对象标记为无效。如果对象被标记为无效，缓存将从始发服务器检索该对象。

45. 发明授权

US08250301B2 Systems and methods of marking large objects as non-cacheable 有权
标题翻译：将大对象标记为不可缓存的系统和方法
公开(公告)号：US08250301B2
公开(公告)日：2012-08-21
申请号：US12020963
申请日：2008-01-28
申请人： Prakash Khemani , Prabakar Sundarrajan , Lakshmi Kumar , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravanakumar Annamalaisami
发明人： Prakash Khemani , Prabakar Sundarrajan , Lakshmi Kumar , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravanakumar Annamalaisami
IPC分类号： G06F12/00
CPC分类号： H04L63/0485 , H04L63/166 , H04L63/168 , H04L67/2842
摘要： A device that implements a method for performing integrated caching in a data communication network. The device is configured to receive a packet from a client over the data communication network, wherein the packet includes a request for an object. At the operating system/kernel level of the device, one or more of decryption processing of the packet, authentication and/or authorization of the client, and decompression of the request occurs prior to and integrated with caching operations. The caching operations include determining if the object resides within a cache, serving the request from the cache in response to a determination that the object is stored within the cache, and sending the request to a server in response to a determination that the object is not stored within the cache.
摘要翻译：实现在数据通信网络中执行集成缓存的方法的设备。该设备被配置为通过数据通信网络从客户端接收分组，其中分组包括对对象的请求。在设备的操作系统/内核级别，分组的解密处理，客户端的认证和/或授权以及请求的解压缩中的一个或多个发生在高速缓存操作之前并且与缓存操作相结合。高速缓存操作包括确定对象是否驻留在高速缓存中，响应于确定对象被存储在高速缓存中而从高速缓存提供请求，以及响应于对象不是的确定将请求发送到服务器存储在缓存中。

46. 发明授权

US08108525B2 Systems and methods for managing a plurality of user sessions in a virtual private network environment 有权
标题翻译：用于在虚拟专用网络环境中管理多个用户会话的系统和方法
公开(公告)号：US08108525B2
公开(公告)日：2012-01-31
申请号：US11462341
申请日：2006-08-03
申请人： Arkesh Kumar , James Harris , Ajay Soni
发明人： Arkesh Kumar , James Harris , Ajay Soni
IPC分类号： G06F15/16
CPC分类号： H04L63/0272 , H04L12/4641 , H04L67/14
摘要： Methods for establishing an SSL/VPN session on behalf of a user of a client where the user has a previously existing session are described. Methods include receiving, by an appliance, a request from a first client operated by a user to establish a virtual private network session; creating, by the appliance, a temporary virtual private network session with the client; identifying, by the appliance, an existing virtual private network session previously established on behalf of the user; terminating the previous session; and creating a new virtual private network session with the client using the temporary session. Other methods may further include transmitting a request to a user corresponding to whether to terminate one or more previous sessions, and transferring session data from a previously existing session to a current session. Corresponding systems are also described.
摘要翻译：描述代表用户具有先前存在的会话的客户端的用户建立SSL / VPN会话的方法。方法包括由设备接收来自用户操作的第一客户机的请求以建立虚拟专用网络会话; 由设备创建与客户端的临时虚拟专用网络会话; 由设备识别以前代表用户建立的现有虚拟专用网络会话; 终止前一届会议; 并使用临时会话与客户端创建新的虚拟专用网络会话。其他方法还可以包括：向用户发送对应于是否终止一个或多个先前会话的请求，以及将会话数据从先前存在的会话传送到当前会话。还描述了相应的系统。

47. 发明申请

US20070156876A1 System and method for performing flash caching of dynamically generated objects in a data communication network 有权
标题翻译：用于在数据通信网络中执行动态生成的对象的快速缓存的系统和方法
公开(公告)号：US20070156876A1
公开(公告)日：2007-07-05
申请号：US11324141
申请日：2005-12-30
申请人： Prabakar Sundarrajan , Prakash Khemani , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravana Annamalaisami , Bharat Bhushan KR , Anil Kumar
发明人： Prabakar Sundarrajan , Prakash Khemani , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravana Annamalaisami , Bharat Bhushan KR , Anil Kumar
IPC分类号： G06F15/173
CPC分类号： H04L67/28 , H04L63/102 , H04L67/2852
摘要： The present invention is directed towards a method and system for providing a technique referred to as flash caching to respond to requests for an object, such as a dynamically generated object, from multiple clients. This technique of the present invention uses a dynamically generated object stored in a buffer for transmission to a client, for example in response to a request from the client, to also respond to additional requests for the dynamically generated object from other clients while the object is stored in the buffer. Using this technique, the present invention is able to increase cache hit rates for extremely fast changing dynamically generated objects that may not otherwise be cacheable.
摘要翻译：本发明涉及一种用于提供被称为闪存缓存以响应来自多个客户端的诸如动态生成的对象的对象的请求的技术的方法和系统。本发明的这种技术使用存储在缓冲器中的动态生成的对象，例如响应于来自客户端的请求，向客户端发送，还响应来自其他客户机的动态生成对象的附加请求，而对象是存储在缓冲区中。使用这种技术，本发明能够增加非常快速变化的动态产生的对象的高速缓存命中率，这些对象可能不是可高速缓存的。

48. 发明申请

US20060015570A1 Method and device for performing integrated caching in a data communication network 有权
标题翻译：用于在数据通信网络中执行集成缓存的方法和设备
公开(公告)号：US20060015570A1
公开(公告)日：2006-01-19
申请号：US11169002
申请日：2005-06-29
申请人： Prakash Khemani , Prabakar Sundarrajan , Lakshmi Kumar , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravanakumar Annamalaisami
发明人： Prakash Khemani , Prabakar Sundarrajan , Lakshmi Kumar , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravanakumar Annamalaisami
IPC分类号： G06F15/16
CPC分类号： H04L63/0485 , H04L63/166 , H04L63/168 , H04L67/2842
摘要： A device that implements a method for performing integrated caching in a data communication network. The device is configured to receive a packet from a client over the data communication network, wherein the packet includes a request for an object. At the operating system/kernel level of the device, one or more of decryption processing of the packet, authentication and/or authorization of the client, and decompression of the request occurs prior to and integrated with caching operations. The caching operations include determining if the object resides within a cache, serving the request from the cache in response to a determination that the object is stored within the cache, and sending the request to a server in response to a determination that the object is not stored within the cache.
摘要翻译：实现在数据通信网络中执行集成缓存的方法的设备。该设备被配置为通过数据通信网络从客户端接收分组，其中分组包括对对象的请求。在设备的操作系统/内核级别，分组的解密处理，客户端的认证和/或授权以及请求的解压缩中的一个或多个发生在高速缓存操作之前并且与缓存操作相结合。高速缓存操作包括确定对象是否驻留在高速缓存中，响应于确定对象被存储在高速缓存中而从高速缓存提供请求，以及响应于对象不是的确定将请求发送到服务器存储在缓存中。

49. 发明授权

US08507670B2 Matrix metalloproteinase inhibitors 有权
标题翻译：基质金属蛋白酶抑制剂
公开(公告)号：US08507670B2
公开(公告)日：2013-08-13
申请号：US12438182
申请日：2007-08-21
申请人： Viswajanani J. Sattigeri , Venkata P. Palle , Manoj Kumar Khera , Ranadheer Reddy , Manoj Kumar Tiwari , Ajay Soni , Abdul Rehman Abdul Rauf , Sony Joseph , Arpita Musib , Sunanda G. Dastidar , Punit Kumar Srivastava
发明人： Viswajanani J. Sattigeri , Venkata P. Palle , Manoj Kumar Khera , Ranadheer Reddy , Manoj Kumar Tiwari , Ajay Soni , Abdul Rehman Abdul Rauf , Sony Joseph , Arpita Musib , Sunanda G. Dastidar , Punit Kumar Srivastava
IPC分类号： C07D253/08 , A61K31/53 , A61P19/02
CPC分类号： A61K31/4155 , A61K31/4035 , A61K31/41 , A61K31/438 , A61K31/4439 , A61K31/444 , A61K31/502 , A61K31/506 , A61K31/517 , A61K31/53 , A61K31/536 , A61K45/06 , C07D209/44 , C07D209/48 , C07D253/08 , C07D265/26 , C07D401/06 , C07D401/10 , C07D401/14 , C07D403/10 , C07D405/10 , C07D409/06 , C07D409/10 , C07D409/14 , C07D413/10
摘要： The present invention relates to β-hydroxy and amino substituted carboxylic acids, which act as matrix metalloprotease inhibitors, particularly diastereomerically pure β-hydroxy carboxylic acids, corresponding processes for the synthesis of and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, periodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase using the compounds.
摘要翻译：本发明涉及β-羟基和氨基取代的羧酸，其作为基质金属蛋白酶抑制剂，特别是非对映体纯的β-羟基羧酸，用于合成的相应方法和含有本发明化合物的药物组合物。本发明的化合物可用于治疗各种炎性，自身免疫性和过敏性疾病，例如治疗哮喘，类风湿性关节炎，COPD，鼻炎，骨关节炎，牛皮癣关节炎，牛皮癣，肺纤维化，伤口愈合障碍，肺部炎症，急性呼吸窘迫综合征，牙周炎，多发性硬化症，牙龈炎，动脉粥样硬化，新生内膜增生，其导致再狭窄和缺血性心力衰竭，中风，肾脏疾病，肿瘤转移和其他炎症性疾病，其特征在于过度表达和过度激活使用该化合物的基质金属蛋白酶。

50. 发明授权

US08499057B2 System and method for performing flash crowd caching of dynamically generated objects in a data communication network 有权
标题翻译：用于在数据通信网络中执行动态生成的对象的闪存人群缓存的系统和方法
公开(公告)号：US08499057B2
公开(公告)日：2013-07-30
申请号：US13031919
申请日：2011-02-22
申请人： Prabakar Sundarrajan , Prakash Khemani , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravana Annamalaisami , Bharath Bushan K. R. , Anil Kumar
发明人： Prabakar Sundarrajan , Prakash Khemani , Kailash Kailash , Ajay Soni , Rajiv Sinha , Saravana Annamalaisami , Bharath Bushan K. R. , Anil Kumar
IPC分类号： G06F15/16 , G06F15/173
CPC分类号： G06F17/30902
摘要： The present invention is directed towards a “flash crowd” technique for handling situations where the cache receives additional requests, e.g., nearly simultaneous requests, for the same object during the time the server is processing and returning the response object for a first requestor. Once all such nearly simultaneous requests are responded to by the cache, the object is flushed from the cache, with no additional expiry time or invalidation action needed. This technique of the present invention enables data to be cached and served for very small amounts of time for objects that would otherwise be considered non-cacheable. As such, this technique yields a significant improvement in applications that serve fast changing data to a large volume of concurrent users, such, for example, as real time stock quotes, or a fast evolving news story.
摘要翻译：本发明涉及一种用于处理高速缓存在服务器处理期间为相同对象接收附加请求（例如几乎同时的请求）并返回第一请求者的响应对象的情况的“闪存人群”技术。一旦所有这些几乎同时的请求都被缓存所响应，则该对象从缓存中刷新，而不需要额外的到期时间或无效操作。本发明的这种技术使数据被缓存并且被服务非常少的时间，否则将被认为是不可缓存的对象。因此，这种技术在将快速变化的数据提供给大量并发用户（例如实时股票报价或快速发展的新闻故事）的应用程序中产生了显着的改进。

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