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41. 发明授权

US06275736B1 Hair clip retention system for headpiece of cochlear implant system 失效
标题翻译：用于耳蜗植入系统头盔的夹子固定系统
公开(公告)号：US06275736B1
公开(公告)日：2001-08-14
申请号：US09312158
申请日：1999-05-14
申请人： Janusz A. Kuzma , Lani A. Smith , Richard P. Malmgren
发明人： Janusz A. Kuzma , Lani A. Smith , Richard P. Malmgren
IPC分类号： A61N136
CPC分类号： H04R25/606 , A61N1/36036 , Y10S128/903
摘要： A hair clip for use with a cochlear implant system retains a headpiece assembly, including a transmitting coil, in an aligned position relative to an implanted stimulator. In one embodiment, the hair clip provides a retention system that uses a magnet which forms part of the transmitting coil. A comb or plurality of prongs forms part of the retention system. In another embodiment, the comb has central teeth that are made from ferromagnetic material, and typically also has a non-central teeth that are made from non-ferromagnetic material. The comb is placed and secured in the patient's hair over the area where a cochlear implant is implanted. The transmitting coil is then placed next to the comb, and the magnet within the transmitting coil attaches to the ferromagnetic teeth of the comb. In another embodiment, the transmitting coil is housed in a headpiece, and the headpiece and comb or hair clip are fastened together, along an edge of the comb or hair clip where the teeth or prongs are bonded, with a hinge attachment spring. In a further embodiment, the hair clip is formed from a single sheet of stainless steel, and a plurality of prongs engage a lower surface of the headpiece while a retaining band, with an integral spring, securely holds the headpiece in place against the prongs. The hair clip is opened by applying a manual force against the spring and retaining band.
摘要翻译：与耳蜗植入系统一起使用的发夹将相对于植入的刺激器保持在对准位置的包括发射线圈的头戴组件。在一个实施例中，发夹提供使用形成发射线圈的一部分的磁体的保持系统。梳子或多个插脚构成保持系统的一部分。在另一个实施例中，梳具有由铁磁材料制成的中心齿，并且通常还具有由非铁磁材料制成的非中心齿。将梳子放置并固定在植入人耳蜗植入物的区域上的患者头发中。然后将发射线圈放置在梳子附近，并且发射线圈内的磁体附着到梳子的铁磁齿上。在另一个实施例中，发射线圈被容纳在头盔中，并且头盔和梳子或发夹沿着梳子或发夹的边缘固定在一起，其中齿或尖头被接合在一起，具有铰链附接弹簧。在另一实施例中，发夹由单片不锈钢形成，并且多个插脚与头戴臂的下表面接合，而具有整体弹簧的保持带牢固地将针头固定在针头上。通过对弹簧和保持带施加手动力来打开发夹。

42. 发明授权

US06266568B1 Inflatable cochlear electrode array and method of making same 失效
标题翻译：充气耳蜗电极阵列及其制作方法
公开(公告)号：US06266568B1
公开(公告)日：2001-07-24
申请号：US09300800
申请日：1999-04-27
申请人： Alfred E. Mann , Thomas H. R. Lenarz , Janusz A. Kuzma , William Vanbrooks Harrison
发明人： Alfred E. Mann , Thomas H. R. Lenarz , Janusz A. Kuzma , William Vanbrooks Harrison
IPC分类号： A61N104
CPC分类号： A61N1/0541
摘要： An inflatable cochlear electrode array adapted for insertion into a human cochlear includes a flexible carrier on which a multiplicity of spaced-apart electrode contacts are carried, preferably along one side, e.g., a medial side, of the carrier. The flexible carrier also includes an inflatable compartment or section. In one embodiment, the inflatable section is located at the distal tip of the electrode array on a side of the flexible carrier that is opposite the electrode contacts. In another embodiment, the inflatable compartment or section is located along at least one half of the full length of the flexible carrier, forming a spine. In either embodiment, the electrode is readily inserted into the cochlea to a desired depth while the inflatable compartment or section remains in a deflated state. Thereafter, a desired modiolus-hugging position is achieved by inflating the inflatable compartment or section by injecting therein a suitable biocompatible fluid. A method of making an inflatable cochlear electrode is also disclosed.
摘要翻译：适于插入到人类耳蜗中的充气耳蜗电极阵列包括柔性载体，其上承载有多个间隔开的电极触点，优选地沿载体的一侧，例如内侧。柔性载体还包括可充气的隔室或部分。在一个实施例中，可充气部分位于与电极接触件相对的柔性载体侧上的电极阵列的远端。在另一个实施例中，可充气隔室或部分沿柔性载体的全长的至少一半定位，形成脊柱。在任一实施例中，电极容易地插入耳蜗到期望的深度，同时可充气隔间或部分保持在放气状态。此后，通过在其中注射合适的生物相容性流体来使充气室或部分膨胀来实现所需的夹层位置。还公开了制造充气耳蜗电极的方法。

43. 发明授权

US6129753A Cochlear electrode array with electrode contacts on medial side 有权
标题翻译：耳蜗电极阵列，内侧具有电极触点
公开(公告)号：US6129753A
公开(公告)日：2000-10-10
申请号：US247734
申请日：1999-02-09
申请人： Janusz A. Kuzma
发明人： Janusz A. Kuzma
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , Y10T29/49117 , Y10T29/49179
摘要： An implantable electrode array, adapted for insertion into a cochlea, provides improved stability of electrode contact direction. In-line electrodes are spaced-apart along one side of a flexible carrier. The structure of the electrode array facilitates bending of the array with the electrode contacts on the inside of the bend, yet deters flexing or twisting of the array in other directions. The electrode contacts preferably are each made from two strips of metal, arranged in a "T" shape (top view). During assembly, all of the "T" strips are held in position on an iron sheet. Two wire bundles are formed that pass along each side of each "T". The leg of each "T" is folded over to pinch at least one of the wires from one of the wire bundles therebetween. This pinched wire is then resistance welded to the strip. The sides of the "T" are then folded up and touch or nearly touch to form a ".DELTA." shape (side view). The wire bundles going to more distal electrodes pass through the ".DELTA." and are thus engaged by the ".DELTA.". A flexible carrier, made from, e.g., silicone rubber, is molded over and around the wire bundles and folded electrode T's, preferably in a slightly curved shape. The iron sheet is chemically etched away, leaving an array of spaced-apart electrode contact areas along one edge of the flexible carrier, each of which is electrically attached to at least one wire which passes through the carrier. The electrode array can be manufactured using low cost technology; and once made can be easily inserted, removed and reinserted, if required, into the cochlea or other curved body cavity.
摘要翻译：适于插入耳蜗的可植入电极阵列提供改善的电极接触方向的稳定性。在线电极沿着柔性载体的一侧间隔开。电极阵列的结构有利于电极触点在弯曲部内侧的阵列的弯曲，而且阻止阵列在其它方向的弯曲或扭转。电极接触件优选地由两条以“T”形（顶视图）排列的金属条制成。在组装期间，所有的“T”条都保持在铁板上的适当位置。形成通过每个“T”的每一侧的两个线束。每个“T”的腿被折叠以从其间的线束之一夹紧至少一根电线。然后将该夹紧的线材电阻焊接到带材上。然后将“T”的侧面折叠起来，触摸或接触以形成“DELTA”形状（侧视图）。穿过更远端电极的电线束通过“DELTA”并因此被“DELTA”接合。由例如硅橡胶制成的柔性载体在电线束和折叠电极T之上和之上被模制，优选地在稍微弯曲的形状。铁板被化学蚀刻掉，留下沿着柔性载体的一个边缘的间隔开的电极接触区域的阵列，每个电极接触区域电连接到穿过载体的至少一根电线。电极阵列可以使用低成本技术制造; 并且一旦制成可以容易地插入，移除并重新插入，如果需要，进入耳蜗或其他弯曲体腔。

44. 发明授权

US6096059A Microsurgical tool 失效
标题翻译：显微手术工具
公开(公告)号：US6096059A
公开(公告)日：2000-08-01
申请号：US251761
申请日：1999-02-18
申请人： Janusz A. Kuzma
发明人： Janusz A. Kuzma
IPC分类号： A61B17/28 , A61B17/30
CPC分类号： A61B17/29 , A61B17/30 , A61B17/2909 , A61B2017/2918 , A61B2017/305
摘要： A microsurgical tool (8), in the form of forceps, allows access and micro-manipulation into very small confined spaces, such as the cochlea. The microsurgical tool includes an activation body (10) and a working head (20). The activation body is made from a pair of leaf springs (11) joined permanently at one end to a sliding bracket (12) and joined at the other end to a central section (15) with removable screws (13). The central section (15) tapers to an extension (15A) that extends to the working head. A push arm (16) has a first end coupled to the sliding bracket (12) and a second end pivotally joined to the working head (20). The working head (20) is made from a first jaw part (21) attached to the extension (15A), and a second jaw part (22) pivotally connected to the second end of the push arm (16). In operation, pressing the pair of leaf springs together forces the sliding bracket to slide forward and close the first and second jaw parts together, while releasing the pair of leaf springs allows the sliding bracket to slide backward to open the jaw parts.
摘要翻译：以镊子形式的显微手术工具（8）允许进入和微操作进入非常小的密闭空间，例如耳蜗。显微手术工具包括激活体（10）和工作头（20）。激活体由一对永久地连接到滑动支架（12）的一对板簧（11）制成，并且在另一端与具有可拆卸的螺钉（13）的中心部分（15）连接。中心部分（15）向延伸到工作头部的延伸部（15A）逐渐变细。推臂（16）具有联接到滑动支架（12）的第一端和枢转地连接到工作头（20）的第二端。工作头（20）由附接到延伸部（15A）的第一钳口部分（21）和可枢转地连接到推动臂（16）的第二端的第二钳口部分（22）制成。在操作中，按压一对板簧一起迫使滑动支架向前滑动并将第一和第二钳口部分一起关闭，同时释放一对板簧允许滑动支架向后滑动以打开颚部件。

45. 发明授权

US6038484A Cochlear electrode with modiolar-hugging system including a flexible positioner 失效
标题翻译：耳蜗电极，包括柔性定位器
公开(公告)号：US6038484A
公开(公告)日：2000-03-14
申请号：US140034
申请日：1998-08-26
申请人： Janusz A. Kuzma
发明人： Janusz A. Kuzma
IPC分类号： A61F2/18 , A61F11/00 , A61N1/05 , H04R25/00
CPC分类号： A61N1/0541
摘要： An electrode system includes (1) an electrode array, made in a straight or curved shape, but made on a flexible carrier so that it can easily bend within a curved body cavity, such as the cochlea; and (2) a flexible positioner, typically molded in a curved shape from a silicone polymer so as to make it easy to slide into the body cavity. Some embodiments may further include an electrode guiding insert. Yet other embodiments include only a flexible positioner adapted to fill space within a human cochlea so as to force an electrode array against a modiolar wall of the cochlea. Insertion of the electrode array is performed using one of two methods. A first method involves first inserting the flexible positioner into the scala tympani (one of the channels of the cochlea) to a desired depth, which desired depth typically involves a rotation of about 360 degrees and causes the positioner to rest against the outer or lateral wall of the scala tympani, leaving an opening slightly larger than the cross-section of the electrode array adjacent the inner wall of the scala tympani, and then second inserting the electrode array into the opening defined by the positioner and inner wall. The guiding insert may be used, in some embodiments, to assist guiding the electrode array into this opening. A second method of insertion involves first inserting an electrode array into the scala tympani, and then second inserting the positioner into the scala tympani so as to lie between the electrode array and the outer wall of the scala tympani, thereby forcing the electrode array against the inner wall of the scala tympani. Insertion of the positioner into scala tympani after the electrode array has been at least partially inserted therein further carries the electrode array deeper into the scala tympani to a desired final position, and maintains it in that position.
摘要翻译：电极系统包括（1）电极阵列，其制成直线或弯曲形状，但制成在柔性载体上，使得其可容易地弯曲在弯曲的体腔内，例如耳蜗; 和（2）柔性定位器，通常由硅氧烷聚合物模制成弯曲形状，以使其容易滑入体腔。一些实施例可以进一步包括电极引导插入件。其它实施例仅包括柔性定位器，其适于填充人耳蜗内的空间，以便迫使电极阵列抵靠耳蜗的模腔壁。使用两种方法之一来进行电极阵列的插入。第一种方法包括首先将柔性定位器插入鼓风鼓（耳蜗的一个通道）到期望的深度，所需的深度通常涉及约360度的旋转，并使定位器抵靠外壁或侧壁的鼓风鼓，留下比邻近鼓膜内壁的电极阵列的横截面略大的开口，然后将电极阵列第二次插入由定位器和内壁限定的开口中。在一些实施例中，引导插入件可用于辅助引导电极阵列进入该开口。第二种插入方法包括首先将电极阵列插入鼓膜鼓中，然后将定位器第二次插入鼓膜鼓中，以便位于电极阵列和鼓膜外壁之间，从而迫使电极阵列抵抗鼓楼的内墙。在将电极阵列至少部分地插入其中之后，将定位器插入鼓鼓鼓中，进一步将电极阵列更深地插入鼓风鼓到期望的最终位置，并将其保持在该位置。

46. 发明授权

US08548604B2 Implantable microstimulators and methods for unidirectional propagation of action potentials 失效
标题翻译：可植入的微型激励器和动作电位单向传播的方法
公开(公告)号：US08548604B2
公开(公告)日：2013-10-01
申请号：US12960722
申请日：2010-12-06
申请人： Todd K. Whitehurst , Rafael Carbunaru , James P. McGivern , Matthew I. Haller , Tom Xiaohai He , Kerry Bradley , Janusz A. Kuzma
发明人： Todd K. Whitehurst , Rafael Carbunaru , James P. McGivern , Matthew I. Haller , Tom Xiaohai He , Kerry Bradley , Janusz A. Kuzma
IPC分类号： A61N1/05
CPC分类号： A61N1/37252 , A61N1/05 , A61N1/0556 , A61N1/36071 , A61N1/37205 , A61N1/37217 , A61N1/37288
摘要： Miniature implantable stimulators (i.e., microstimulators) are capable of producing unidirectionally propagating action potentials (UPAPs). The methods and configurations described may, for instance, arrest action potentials traveling in one direction, arrest action potentials of small diameters nerve fibers, arrest action potentials of large diameter nerve fibers. These methods and systems may limit side effects of bidirectional and/or less targeted stimulation.
摘要翻译：微型植入式刺激器（即微型刺激器）能够产生单向传播动作电位（UPAP）。所描述的方法和结构可以例如阻止在一个方向上行进的动作电位，阻止小直径神经纤维的动作电位，阻止大直径神经纤维的动作电位。这些方法和系统可以限制双向和/或较少靶向刺激的副作用。

47. 发明申请

US20130023972A1 ELECTRODE ARRAY ASSEMBLY AND METHOD OF MAKING SAME 有权
标题翻译：电极阵列组件及其制造方法
公开(公告)号：US20130023972A1
公开(公告)日：2013-01-24
申请号：US13620099
申请日：2012-09-14
申请人： Janusz A. Kuzma , Anne M. Pianca
发明人： Janusz A. Kuzma , Anne M. Pianca
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0551 , A61N1/0553 , Y10T29/49117 , Y10T29/49204 , Y10T29/49208 , Y10T29/4922
摘要： A lead assembly and a method of making a lead are provided. The method of making a multi-contact lead assembly comprises placing monofilament placed in the void spaces not occupied by the plurality of conductor wires and, in one embodiment, thermally fusing the monofilament to the like material spacer by applying heat just below the melting temperature of the monofilament and spacer material. Alternatively, the monofilament and spacer may be of different materials and heat is applied to cause at least one material to thermally reflow or melt. The conductive contacts may be located at either the distal end and/or proximal end of the lead. Oversized spacers may be used in order to provide extra material to fill voids during the thermal fusion/reflow process.
摘要翻译：提供引线组件和引线的方法。制造多接触引线组件的方法包括放置放置在未被多根导线占据的空隙空间中的单丝，并且在一个实施例中，通过施加刚好低于熔融温度单丝和间隔材料。或者，单丝和间隔件可以是不同的材料，并且施加热量以使至少一种材料热回流或熔化。导电触点可以位于引线的远端和/或近端处。可以使用超大间隔物，以便在热熔/回流过程期间提供额外的材料以填充空隙。

48. 发明授权

US08321028B1 Impact resistant implantable antenna coil assembly 有权
标题翻译：耐冲击植入式天线线圈组件
公开(公告)号：US08321028B1
公开(公告)日：2012-11-27
申请号：US12326804
申请日：2008-12-02
申请人： Chuladatta Thenuwara , William A. Morgan , Janusz A. Kuzma
发明人： Chuladatta Thenuwara , William A. Morgan , Janusz A. Kuzma
IPC分类号： A61N1/00
CPC分类号： A61N1/37229 , A61N1/36036
摘要： An impact resistant implantable antenna coil assembly comprising a flat antenna coil having a plurality of laterally separated turns of wire encapsulated with a non-orthogonal force absorbing coil reinforcement in a flexible biocompatible polymer and axially anchored with the reinforcement to a feedthrough case. Thus configured, non-orthogonal impact forces applied to the antenna coil assembly are absorbed and lateral components thereof that would otherwise be reflected as tensile forces in the plane of the coil are prevented from forming or from fracturing wire within the antenna coil.
摘要翻译：一种耐冲击植入式天线线圈组件，其包括平面天线线圈，该平面天线线圈具有多个横向分开的导线，其缠绕在柔性生物相容性聚合物中并且与所述加强件轴向锚固到馈通壳体上，所述线圈被非正交力吸收线圈加强件包封。因此，被施加到天线线圈组件的这种被配置的非正交冲击力被吸收，否则将被反射成线圈平面中的拉力的其横向分量被防止在天线线圈内形成或断裂线。

49. 发明申请

US20090240258A1 DETACHABLE HANDLE FOR IMPLANTABLE ELECTRICAL STIMULATION SYSTEMS AND METHODS OF MAKING AND USING 审中-公开
标题翻译：用于可植入电刺激系统的可拆卸手柄及其制造和使用方法
公开(公告)号：US20090240258A1
公开(公告)日：2009-09-24
申请号：US12406885
申请日：2009-03-18
申请人： Janusz A. Kuzma , Anne Margaret Pianca , Lani A. Smith
发明人： Janusz A. Kuzma , Anne Margaret Pianca , Lani A. Smith
IPC分类号： A61B17/00
CPC分类号： A61N1/056 , A61B2017/00469
摘要： A detachable handle includes a handle body that is substantially tubular and defines a hollow center region extending at least a portion of a longitudinal length of the handle body. The handle body is configured and arranged to receive a portion of a stylet handle within the hollow center region and removably attach to the stylet handle. The handle body includes an external gripping surface extending at least a portion of an exterior surface of the handle body.
摘要翻译：可拆卸手柄包括手柄主体，该手柄主体基本上是管状的并且限定了延伸至手柄主体的纵向长度的至少一部分的中空中心区域。手柄主体被构造和布置成接收在中空中心区域内的探针手柄的一部分并且可移除地附接到探针手柄。手柄本体包括延伸手柄主体的外表面的至少一部分的外部夹持表面。

50. 发明授权

US07444180B2 Implantable microstimulator with dissecting tip and/or retrieving anchor and methods of manufacture and use 失效
标题翻译：具有解剖尖端和/或检索锚的可植入微型刺激器以及制造和使用方法
公开(公告)号：US07444180B2
公开(公告)日：2008-10-28
申请号：US11138598
申请日：2005-05-25
申请人： Janusz A. Kuzma , Tom Xiaohai He , Anne Pianca
发明人： Janusz A. Kuzma , Tom Xiaohai He , Anne Pianca
IPC分类号： A61N1/00
CPC分类号： A61N1/375 , A61N1/0551 , A61N1/36003 , A61N1/37205 , A61N1/3756 , A61N2001/0578
摘要： An implantable microstimulator can include a housing having a first end; an electronic subassembly disposed within the housing; a plurality of electrodes disposed on the housing and coupled to the electronic subassembly; and a dissecting tip disposed at the first end of the housing. Another implantable microstimulator includes a housing having a first end; an electronic subassembly disposed within the housing; a plurality of electrodes disposed on the housing and coupled to the electronic subassembly; and a extraction aid disposed at the first end of the housing and configured and arranged for attachment of an extraction line.
摘要翻译：可植入微型刺激器可以包括具有第一端的壳体; 设置在所述壳体内的电子组件; 多个电极，设置在所述壳体上并联接到所述电子子组件; 以及设置在所述壳体的第一端处的解剖尖端。另一种可植入微型激励器包括具有第一端的外壳; 设置在所述壳体内的电子组件; 多个电极，设置在所述壳体上并联接到所述电子子组件; 以及设置在壳体的第一端处并被构造和布置成用于附接提取管线的提取助剂。

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