专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

US20170238834A1 BIOMAGNETISM MEASUREMENT DEVICE 审中-公开
公开(公告)号：US20170238834A1
公开(公告)日：2017-08-24
申请号：US15501777
申请日：2015-08-05
申请人： National University Corporation Tokyo Medical and Dental University , TDK CORPORATION
发明人： Shigenori KAWABATA , Satoshi SUMIYA , Shuichi OKAWA
IPC分类号： A61B5/05
CPC分类号： A61B5/05 , A61B5/04005 , A61B5/04007 , A61B5/04009 , A61B5/0515 , A61B5/062 , A61B5/4064 , A61B5/407 , A61B5/6852 , A61B5/6853 , A61B5/6868 , A61B5/687 , A61B5/6873 , A61B5/6876 , A61B5/6885 , A61B2562/043
摘要： A biomagnetism measurement device includes a tubular body, an inflatable portion inflatable upon supply of gas, and a magnetic sensor portion that detects a magnetic field from outside the tubular body. The inflatable portion is located at a required region of the tubular body, and the magnetic sensor portion is fixed to an inner wall of the inflatable portion. The tubular body and the inflatable portion include the same material, and the wall thickness of the inflatable portion is thinner than that of the tubular body.

42. 发明申请

US20170029389A1 PAIN-RELATED COMPOUND AND MEDICAL COMPOSITION 有权
标题翻译：与PAIN相关的化合物和医药组合物
公开(公告)号：US20170029389A1
公开(公告)日：2017-02-02
申请号：US15105985
申请日：2014-12-18
申请人： KYOTO UNIVERSITY , NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY , KAGOSHIMA UNIVERSITY
发明人： Masatoshi HAGIWARA , Masayasu TOYOMOTO , Takamitsu HOSOYA , Suguru YOSHIDA , Takashi KURIHARA
IPC分类号： C07D277/64
CPC分类号： C07D277/64
摘要： Provided is a pain-related compound, a pain-related pharmaceutical composition, and use of the same. Provided in one or more embodiments is a compound represented by Formula (I), a prodrug of the same, or a pharmaceutically permissible salt of any of the same.
摘要翻译：提供疼痛相关化合物，疼痛相关药物组合物及其用途。在一个或多个实施方案中提供由式（I）表示的化合物，其前体药物或其药学上可允许的盐。

43. 发明申请

US20160199512A1 POLYROTAXANE AND MEDICINAL COMPOSITION 审中-公开
标题翻译：聚氨酯和药物组合物
公开(公告)号：US20160199512A1
公开(公告)日：2016-07-14
申请号：US14913978
申请日：2014-08-18
申请人： National University Corporation Tokyo Medical and Dental University
发明人： Atsushi Tamura , Nobuhiko Yui
IPC分类号： A61K47/48 , A61K9/00
CPC分类号： A61K47/6951 , A61K9/0085
摘要： A medicinal composition for diseases caused by dyslipidemia and/or autophagy dysfunction, etc., said medicinal composition comprising polyrotaxane that carries bulky substituents introduced, via intracellularly degradable bonds, into both ends of a linear molecule penetrating through plural cyclic molecules.
摘要翻译：由血脂异常和/或自噬功能障碍引起的疾病的药物组合物等，所述药物组合物含有通过细胞内可降解的键引入的大体积取代基的多聚轮烷进入穿过多个环状分子的线性分子的两端。

44. 发明申请

US20160051731A1 HYBRID GEL COMPRISING PARTICULATE DECELLULARIZED TISSUE 审中-公开
标题翻译：混合凝胶包裹颗粒状细胞组织
公开(公告)号：US20160051731A1
公开(公告)日：2016-02-25
申请号：US14888871
申请日：2014-05-02
申请人： THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE , NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY , SAPPORO MEDICAL UNIVERSITY , ADEKA CORPORATION
发明人： Junichi MATSUDA , Sumika MIYABASHIRA , Satomi HARANO , Akio KISHIDA , Tsuyoshi KIMURA , Jun NEGISHI , Tetsuya HIGAMI , Seiichi FUNAMOTO , Ken-ichiro HIWATARI , Akiko TASAKI
IPC分类号： A61L27/52 , A61L27/22 , A61L27/26 , C12N5/00 , A61L27/36
CPC分类号： A61L27/52 , A61K35/22 , A61K35/30 , A61K35/34 , A61K35/407 , A61K35/42 , A61K38/363 , A61K38/4833 , A61L27/225 , A61L27/26 , A61L27/3633 , A61L27/3683 , A61L27/3691 , A61L27/3695 , A61L27/54 , A61L2430/00 , A61L2430/20 , A61L2430/32 , C12N5/0068 , C12N2533/50 , C12N2533/56 , C12N2533/90
摘要： A hybrid gel comprising a particulate decellularized tissue (obtained by pulverizing animal-derived biological tissues that are decellularized (decellularized biological tissues)), fibrinogen and thrombin; a cell culture material comprising the hybrid gel; a method for preparing the hybrid gel; and a kit comprising a particulate decellularized tissue and a biological tissue adhesive are provided. The hybrid gel of the present invention exerts the effect to promote differentiation and gain of function of stem cells and the therapeutic effect to a variety of diseases.
摘要翻译：一种混合凝胶，其包含颗粒脱细胞组织（通过粉碎去细胞化的（来自脱细胞的生物组织）的动物衍生的生物组织），纤维蛋白原和凝血酶获得; 包含所述杂交凝胶的细胞培养物质; 制备混合凝胶的方法; 并提供了包含颗粒脱细胞组织和生物组织粘合剂的试剂盒。本发明的混合凝胶发挥促进干细胞分化和增殖功能的效果以及对各种疾病的治疗效果。

45. 发明申请

US20150314163A1 MOUTH-OPENING TRAINING DEVICE 审中-公开
标题翻译：开放式培训设备
公开(公告)号：US20150314163A1
公开(公告)日：2015-11-05
申请号：US14654130
申请日：2013-12-18
申请人： NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
发明人： Hiroyuki YOSHITAKE
IPC分类号： A63B23/03
CPC分类号： A63B23/032 , A61H1/02 , A61H2201/0153 , A61H2201/1253 , A61H2201/1604 , A61H2201/1647 , A61H2201/1676 , A61H2205/026 , A63B23/03
摘要： The purpose of the present invention is to provide a mouth-opening training device with which continuous rotational movement and anterior sliding movement of the temporomandibular joint can be performed smoothly, the device thereby being capable of guiding the movement of the mandible so as to trace an actual mandibular mouth-opening movement. The mouth-opening training device is provided with: an upper member, the base end of which is grasped and the tip of which can engage with a user's maxilla; a lower member, the tip of which can engage with the user's mandible and a portion of which is in contact with the upper member so as to allow sliding; and a connecting section for connecting the upper member to the lower member so as to allow sliding and allow opening and closing. As the tip of the upper member is opened with respect to the tip of the lower member, the lower member moves in the direction of the tip.
摘要翻译：本发明的目的是提供一种开口训练装置，其能够平稳地执行颞下颌关节的连续旋转运动和前滑动运动，因此该装置能够引导下颌骨的运动，以便跟踪实际下颌开口运动。开口训练装置设置有：上部构件，其基端被抓握并且其尖端可与使用者的上颌骨接合; 下部构件，其尖端可与使用者的下颌骨接合，并且其一部分与上部构件接触以允许滑动; 以及用于将上部构件连接到下部构件以便允许滑动并允许打开和关闭的连接部分。当上部构件的尖端相对于下部构件的顶端打开时，下部构件沿尖端的方向移动。

46. 发明申请

US20150225421A1 COMPOUND AND PHARMACEUTICAL COMPOSITION FOR NEUROPSYCHOLOGICAL DISORDER OR MALIGNANT TUMOR 有权
标题翻译：神经病理障碍或恶性肿瘤的化合物和药物组合物
公开(公告)号：US20150225421A1
公开(公告)日：2015-08-13
申请号：US14418342
申请日：2013-07-30
申请人： KYOTO UNIVERSITY , NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY , KINOPHARMA, INC.
发明人： Masatoshi Hagiwara , Hiroshi Onogi , Isao Kii , Takamitsu Hosoya , Yuto Sumida
IPC分类号： C07D513/04 , C07D405/06 , C07D417/06
CPC分类号： C07D513/04 , C07D405/06 , C07D417/06
摘要： The present invention provides a compound and a pharmaceutical composition for neuropsychological disorders or malignant tumors, the use of the compound and the pharmaceutical composition, or a method for preventing, improving, inhibiting the development of, and/or treating neuropsychological disorders or malignant tumors with the use of the compound and the pharmaceutical composition. One or more embodiments disclose a compound expressed by the following general formula (I) or (II) or a pharmaceutically acceptable salt of the compound:
摘要翻译：本发明提供了用于神经心理学障碍或恶性肿瘤的化合物和药物组合物，该化合物和药物组合物的用途，或用于预防，改善，抑制发展和/或治疗神经心理障碍或恶性肿瘤的方法，使用该化合物和药物组合物。一个或多个实施方案公开了由以下通式（I）或（II）表示的化合物或其化合物的药学上可接受的盐：

47. 发明授权

US08975403B2 Process for producing substituted benzo[F]imidazo[1,2-A]quinoxalin-3(11H)-ones 有权
标题翻译：取代苯并[F]咪唑并[1,2-A]喹喔啉-3（11H）酮的制备方法
公开(公告)号：US08975403B2
公开(公告)日：2015-03-10
申请号：US14189706
申请日：2014-02-25
申请人： JNC Corporation , National University Corporation Tokyo Medical and Dental University
发明人： Satoshi Inouye , Yuiko Miura , Suguru Yoshida , Takamitsu Hosoya
IPC分类号： C07D241/36 , C07D487/04 , C07D241/38 , C07D241/44 , C07D241/54
CPC分类号： C07D241/38 , C07D241/20 , C07D241/44 , C07D241/54 , C07D487/04 , Y02P20/55
摘要： A simple process for producing v-coelenterazine compounds has been desired. Described is a process for producing a v-coelenterazine compound represented by general formula (II) comprising (1) the step of reacting a compound of general formula (VIII) with a methyltriphenylphosphonium salt in the presence of a base to give a compound represented by general formula (IX), (2) the step of performing a ring-closing metathesis reaction on any one selected from the group consisting of the compound represented by general formula (IX) and a compound of general formula (X) which is the compound of general formula (IX) wherein the amino is protected with R5, and then deprotecting R4 and, if any, R5 to give a v-coelenteramine compound represented by general formula (XIV), and (3) the step of reacting the compound of general formula (XIV) with a compound represented by general formula (XV) to give the compound of general formula (II).
摘要翻译：已经需要制备v-肠溶纤维素化合物的简单方法。本发明描述了一种制备由通式（II）表示的β-环糊精化合物的方法，包括（1）在碱存在下使通式（Ⅷ）化合物与甲基三苯基鏻盐反应，得到由通式（IX），（2）对选自由通式（IX）表示的化合物和作为化合物的通式（X）的化合物的任何一种进行闭环复分解反应的步骤的通式（IX）的化合物，其中氨基被R 5保护，然后使R 4和（如果有的话）R 5脱保护，得到由通式（XIV）表示的v-内网络胺化合物，和（3）通式（XIV）与通式（XV）表示的化合物反应，得到通式（II）的化合物。

48. 发明申请

US20140271317A1 BIOCOMPATIBLE Co-Cr-Mo ALLOY 审中-公开
标题翻译：生物交联Co-Cr-Mo合金
公开(公告)号：US20140271317A1
公开(公告)日：2014-09-18
申请号：US14352216
申请日：2012-10-18
申请人： KYOCERA Medical Corporation , NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
发明人： Naoyuki Nomura , Takao Hanawa
IPC分类号： C22C19/07 , B22F3/105
CPC分类号： C22C19/07 , A61L27/045 , A61L27/047 , A61L31/022 , B22F3/1055 , C22C1/0433 , Y02P10/295
摘要： The present invention is to provide a Co—Cr—Mo alloy excellent in mechanical properties such as yield strength and tensile strength. The present invention is a biocompatible Co—Cr—Mo alloy comprising, in mass %, more than 30% and not more than 36% of Cr, 5 to 8% of Mo, 0.20 to 0.65% of N, and the balance consisting of Co and inevitable impurities, and produced by layered manufacturing. The biocompatible Co—Cr—Mo alloy of the present invention preferably has a solidification structure of a dendrite structure and the primary arm spacing of the dendrite structure is not more than 5 μm.
摘要翻译：本发明提供一种机械性能如屈服强度和拉伸强度优异的Co-Cr-Mo合金。本发明是一种生物相容性的Co-Cr-Mo合金，以质量％计含有30％以上且36％以下的Cr，5〜8％的Mo，0.20〜0.65％的N，余量由 Co和不可避免的杂质，并通过分层制造生产。本发明的生物相容性Co-Cr-Mo合金优选具有枝晶结构的固化结构，枝晶结构的主臂间隔不大于5μm。

49. 发明申请

US20140248690A1 LIQUID REFLUX HIGH-SPEED GENE AMPLIFICATION DEVICE 审中-公开
标题翻译：液体REFLUX高速基因放大器件
公开(公告)号：US20140248690A1
公开(公告)日：2014-09-04
申请号：US14273673
申请日：2014-05-09
申请人： KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY , NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
发明人： Hiroyuki Takei , Hideyuki TERAZONO , Kenji YASUDA
IPC分类号： B01L7/00 , C12Q1/68
CPC分类号： B01L7/52 , B01L3/50851 , B01L3/50855 , B01L2300/185 , B01L2400/0622 , B01L2400/0633 , B01L2400/0644 , C12Q1/686 , F28D7/0008 , F28D15/00 , F28D2021/0077 , F28F27/02 , F28F2280/02
摘要： One embodiment provides a liquid reflux reaction control device comprising: a reaction vessel having one or a plurality of wells configured to accommodate a sample; a heat exchange vessel provided in contact with the reaction vessel so as to conduct heat to the reaction vessel, and comprising an inlet and an outlet respectively for introducing and draining a liquid of a predetermined temperature; a plurality of liquid reservoir tanks provided with a temperature-controllable heat source for maintaining liquids of predetermined temperatures; a tubular flow channel that connects the inlet and the outlet of the heat exchange vessel with the liquid reservoir tanks; a pump disposed on the tubular flow channel, and configured to circulate the liquid between the heat exchange vessel and the liquid reservoir tank; and a switching valve disposed on the tubular flow channel, and configured to control the flow of the circulating liquid.
摘要翻译：一个实施方案提供了一种液体回流反应控制装置，包括：具有配置成容纳样品的一个或多个阱的反应容器; 设置为与反应容器接触以便将热量传导到反应容器的热交换容器，并且包括分别用于引入和排出预定温度的液体的入口和出口; 设置有用于保持预定温度的液体的温度可控热源的多个储液箱; 连接热交换容器的入口和出口与液体储存罐的管状流动通道; 泵，其设置在所述管状流动通道上，并且构造成使所述液体在所述热交换容器和所述储液箱之间循环; 以及设置在所述管状流路上的切换阀，其构成为控制所述循环液的流动。

50. 发明申请

US20140170331A1 BIOMATERIAL, JOINT PROSTHESIS USING THE BIOMATERIAL AND METHOD OF PRODUCING THE SAME 有权
标题翻译：生物材料，使用生物材料的联合优势及其生产方法
公开(公告)号：US20140170331A1
公开(公告)日：2014-06-19
申请号：US14186183
申请日：2014-02-21
申请人： KYOCERA Medical Corporation , NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY , THE UNIVERSITY OF TOKYO
发明人： Masayuki KYOMOTO , Kazuhiko ISHIHARA , Yasuhiko IWASAKI , Toru MORO , Kozo NAKAMURA , Yoshio TAKATORI , Hiroshi KAWAGUCHI , Tomohiro KONNO , Noboru YAMAWAKI
IPC分类号： A61L27/34 , B05D3/06 , B05D1/18
CPC分类号： A61L27/34 , A61F2/30767 , A61F2/32 , A61F2/34 , A61F2002/30685 , A61F2002/30934 , A61F2002/3611 , A61F2310/00011 , A61F2310/00179 , A61L27/42 , B05D1/18 , B05D3/067 , B23K35/3618 , C22F1/11 , C22F1/183 , Y10T428/24917 , Y10T428/24926 , Y10T428/31536
摘要： The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.
摘要翻译：本发明的目的是提供一种关节假体，轴承材料及其制造方法，其抑制滑动部分的磨损，并且即使在重复的日常操作中也抑制磨料粉末的生产。为了实现该目的，提供了一种生物材料，包括：由金属，合金或陶瓷制成的基底; 以及层叠在基材上的生物相容性材料层，其中通过表面处理在基材上形成羟基，而生物相容性材料层包含含有磷酸胆碱基团的聚合物，基材和生物相容性材料层通过粘合剂层结合，与基材的羟基和生物相容性材料层结合。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式