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    • 46. 发明申请
    • LOCATION SPECIFIC SEARCH FOR REGIONAL SATELLITE VEHICLES
    • 位置特定搜索区域卫星车辆
    • US20090318167A1
    • 2009-12-24
    • US12145361
    • 2008-06-24
    • Rayman Wai PonMarc IscheBorislav RisticJie Wu
    • Rayman Wai PonMarc IscheBorislav RisticJie Wu
    • H04Q7/20
    • G01S19/252G01S19/06
    • A position location system, method, and apparatus are disclosed. A wireless device receives a first signal and obtains an identifier indicative of a first location from the first signal. The first signal can be received from a cellular base station and the first identifier can be a mobile country code. The wireless device uses the identifier to determine the availability of signals from a regional satellite system at the first location. If signals from the regional satellite system are available at the first location, the wireless device retrieves information associated with one or more satellite vehicles in the regional satellite system. The information can include pseudo-random number codes and a Doppler search range corresponding to the first location. The wireless device receives a second signal and processes the second signal to obtain first satellite signal information. The wireless device determines its position at least partially based on the first satellite signal information.
    • 公开了位置定位系统,方法和装置。 无线设备接收第一信号并且从第一信号获得指示第一位置的标识符。 可以从蜂窝基站接收第一信号,并且第一标识符可以是移动国家代码。 无线设备使用标识符来确定来自第一位置的区域卫星系统的信号的可用性。 如果来自区域卫星系统的信号在第一位置可用,则无线设备检索与区域卫星系统中的一个或多个卫星车辆相关联的信息。 该信息可以包括对应于第一位置的伪随机数码和多普勒搜索范围。 无线设备接收第二信号并处理第二信号以获得第一卫星信号信息。 无线设备至少部分地基于第一卫星信号信息确定其位置。
    • 48. 发明申请
    • OPTICAL AMPLIFYING APPARATUS
    • 光学放大装置
    • US20080205460A1
    • 2008-08-28
    • US12014514
    • 2008-01-15
    • Takeo OKANIWAJie WuNobuyuki KagiToru Yoshikawa
    • Takeo OKANIWAJie WuNobuyuki KagiToru Yoshikawa
    • H01S3/13
    • H04B10/294H01S3/06754H01S3/09415H01S3/10015H01S3/10069H01S3/1301H01S3/1305H04B10/2931
    • The present invention provides an optical amplifying apparatus having: a CPU 11 for processing various signals; a plurality of circuits 17, 18 for controlling respective devices 4, 9 required for optical amplification; a first storing unit 14 for storing a program supplied from a user a gate array 12 for storing various parameters for controlling the devices 4, 9, the gate array being updated based on the program which is stored in the first storing unit 14 and sent via the CPU 11; a latch unit 13, provided between the gate array 12 and the circuits 17, 18, for interrupting a signal path from the gate array 12 to the circuits 17, 18 after receiving a starting signal of an update from the CPU 11 until the update being finished and for controlling the circuits 17, 18 based on the parameters stored in the gate array 12 before the signal path is interrupted; and a second storing unit 16 for, at least during the update, storing the various parameters which are stored in the gate array 12 before the update.
    • 本发明提供一种具有:用于处理各种信号的CPU 11的光放大装置; 用于控制光放大所需的各个装置4,9的多个电路17,18; 第一存储单元14,用于存储从用户提供的程序,用于存储用于控制设备4,9的各种参数的门阵列12,基于存储在第一存储单元14中的程序更新门阵列,并经由 CPU 11; 锁存单元13,设置在门阵列12和电路17,18之间,用于在接收到来自CPU 11的更新的起始信号直到更新为止之后中断从门阵列12到电路17,18的信号路径 在信号路径被中断之前基于存储在门阵列12中的参数来完成并控制电路17,18; 以及第二存储单元16,用于至少在更新期间,存储在更新之前存储在门阵列12中的各种参数。
    • 49. 发明申请
    • Method for Decreasing Nicotine and Other Substance Use in Humans
    • 减少人体中尼古丁和其他物质使用的方法
    • US20080176887A1
    • 2008-07-24
    • US11972993
    • 2008-01-11
    • Jie Wu
    • Jie Wu
    • A61K31/435A61K31/20A61P25/34
    • A61K36/185
    • A method for decreasing nicotine and other substance use in humans is disclosed. Tetrahydroberberine (THB) and its analogs, l-Tetrahydropalmatine (l-THP) and l-Stepholidine (l-SPD), are present in and can be isolated from several plants in the Magnoliidae superorder. According to the disclosed method, THB and its analogs are used to block nicotine-induced DA release, and modulate heterologous or homoeric expression of human nicotinic acetylcholine receptors (nAChR) in humans. Specifically, THB exhibits bi-directory modulation of α4β2-nAChR-mediated currents induced by nicotine. THB also shows predominant inhibition on homologously expressed α7-nAChR function. Thus, according to the disclosed method, THB is used to simultaneous blockade midbrain DA system function, the brain reward center, and neuronal α4β2- and α7-nAChR function, the major nicotine targets in the brain. Therefore, THB and its analogs serve as a novel class of natural compounds to decrease nicotine dependence in humans. Furthermore other substances, such as alcohol, cocaine, and opiates, also operate by triggering the brain reward center, resulting in a cycle of substance or alcohol abuse. THB and its analogs can be used to decrease use of substances such as alcohol, cocaine, and opiates. Finally, because THB and its analogs are DA antagonists, THB and its analogs can also be used as a treatment for Parkinson's Disease, Alzheimer's Disease and Schizophrenia.
    • 公开了一种减少人体中尼古丁和其他物质使用的方法。 四氢小檗碱(THB)及其类似物1-四氢al嗪(1-THP)和1- Step hol啶(1-SPD)存在于并可以从Magnoliidae超级序列中的几种植物中分离出来。 根据所公开的方法,泰铢及其类似物用于阻断尼古丁诱导的DA释放,并调节人类烟碱乙酰胆碱受体(nAChR)的异源或同源性表达。 具体来说,泰铢表现出由尼古丁诱导的α4β2-nAChR介导的电流双目录调制。 THB也显示出对同源表达的α7-nAChR功能的主要抑制作用。 因此,根据所公开的方法,泰铢用于同时封锁中脑DA系统功能,脑回报中心和神经元α4β2和α7-nAChR功能,大脑中主要的尼古丁目标。 因此,泰铢及其类似物作为一类新型天然化合物,可以减少人体尼古丁依赖。 此外,其他物质,如酒精,可卡因和阿片剂,也可以通过触发大脑的回报中心,导致物质或酒精滥用的循环。 泰铢及其类似物可用于减少酒精,可卡因和阿片剂等物质的使用。 最后,由于泰铢及其类似物是DA拮抗剂,泰铢及其类似物也可用作帕金森病,阿尔茨海默病和精神分裂症的治疗。