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41. 发明授权

US09846319B2 Pockels cell driver circuit comprising resistive, inductive or capacitive elements 有权
公开(公告)号：US09846319B2
公开(公告)日：2017-12-19
申请号：US15229701
申请日：2016-08-05
申请人： BME Messgeräte Entwicklung KG , Helmholtz-Zentrum Dresden-Rossendorf e.V.
发明人： Thorald Horst Bergmann , Fedor Bergmann , Mathias Siebold , Markus Löser
IPC分类号： H03B1/00 , H03K3/00 , G02F1/03 , H01S3/107 , H03K5/07 , H01S3/10 , H01S3/16
CPC分类号： G02F1/0327 , G02F1/03 , H01S3/10038 , H01S3/10061 , H01S3/107 , H01S3/1618 , H01S3/1643 , H01S3/235 , H03K5/07
摘要： The driver circuit comprises a first node (J1), which is connected to a first terminal of the Pockels cell (CP), a second node (J2), which is connected to a second terminal of the Pockels cell (CP), wherein the first node (J1) is connected to a first potential (+HV) via a first switching unit (S1) and the second node (J2) is connected to the first potential (+HV) via a second switching unit (S2) and wherein the first node (J1) is connected to a second potential (−HV) via a first resistance (R1) and the second node (J2) is connected to the second potential (−HV) via a second resistance (R2); and wherein the first node (J1) is connected to the second node (J2) via a series circuit comprising a third resistance (R3) and an inductance (L1).

42. 发明申请

US20160027606A1 ARRANGEMENT FOR A QUICK ELECTRON BEAM X-RAY COMPUTER TOMOGRAPHY 审中-公开
标题翻译：快速电子束X射线计算机图像的安排
公开(公告)号：US20160027606A1
公开(公告)日：2016-01-28
申请号：US14781404
申请日：2014-04-02
申请人： HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V.
发明人： Frank BARTHEL
IPC分类号： H01J35/14 , H01J35/08 , H05G1/02
CPC分类号： H01J35/14 , H01J35/08 , H01J35/30 , H01J2235/163 , H05G1/02
摘要： A system for electron beam X-ray computer tomography, which requires no considerable axial extension of the electron emitter and substantially eliminates electron-optical beam guidance elements is provided by disposing an X-ray detector arc and the target around the examination cross-section within an irradiation plane, and radially introducing an electron beam generated in the electron beam generator into the magnetic flux region of one or more longitudinal coils from within or outside the coils and forcing the same onto a circular path by way of the magnetic field. By periodically changing the field strength, the radius of the circular path is increased, as a result of which the electron beam impinges on the target in a tangentially migrating focal spot. Radiography projections of the object located in the center of the system are recorded by the X-ray detector surrounding the target, the target and x-ray detector planes being with or without axial offset.
摘要翻译：一种电子束X射线计算机断层摄影系统，其不需要电子发射器的相当大的轴向延伸并且基本上消除电子束引导元件，是通过将X射线检测器电弧和目标围绕检查横截面设置在照射平面，并且将从电子束发生器中产生的电子束径向地引入到线圈内部或外部的一个或多个纵向线圈的磁通量区域中，并且通过磁场将其强制到圆形路径上。通过周期性地改变场强，循环路径的半径增加，结果电子束在切向迁移的焦斑中撞击靶。位于系统中心的物体的射线照相投影由围绕目标的X射线检测器记录，目标和X射线检测器平面具有或不具有轴向偏移。

43. 发明申请

US20160011136A1 ARRANGEMENT FOR DETERMINING THE PHASE DISTRIBUTION IN MULTIPHASE MEDIA HAVING AT LEAST ONE HIGHLY C0NDUCTIVE PHASE 有权
标题翻译：用于确定具有至少一个高级相位的多媒体媒体中的相位分布的布置
公开(公告)号：US20160011136A1
公开(公告)日：2016-01-14
申请号：US14771070
申请日：2014-02-28
申请人： HELMHOLTZ-ZENTRUM DRESDEN - ROSSENDORF E. V.
发明人： Eckhard SCHLEICHER , Martin LOSCHAU , Laurens VAN CAMPEN
IPC分类号： G01N27/22
CPC分类号： G01N27/223 , G01F1/662 , G01F1/74 , G01N27/07 , G01N27/08 , G01N27/221 , G01N27/226 , G01N33/2823
摘要： A grid sensor for measuring the phase distribution of a multiphase substance mixture with gaseous and liquid components in the presence of a highly conductive phase (such as salt water or liquid metal) employs 3 superposed electrode planes and an electronic measuring device. Application areas include determination of the liquid distribution and the fill level in containers, as well as the investigation of gas-liquid multiphase flows, in particular in pipelines, e.g. in petroleum production and processing.
摘要翻译：用于在高导电相（如盐水或液态金属）存在下测量具有气态和液态组分的多相物质混合物的相分布的栅格传感器采用3个重叠的电极平面和电子测量装置。应用领域包括确定容器中的液体分布和填充水平，以及气 - 液多相流动的调查，特别是在管道中的测量。在石油生产和加工。

44. 发明申请

US20140377176A1 Functionalised silicon nanoparticles 审中-公开
标题翻译：官能化硅纳米粒子
公开(公告)号：US20140377176A1
公开(公告)日：2014-12-25
申请号：US14364245
申请日：2012-12-12
申请人： Westfaelische Wilhelms-Universitaet Muenster , Helmholtz-Zentrum Dresden-Rossendorf
发明人： Holger Stephan , Ralf Bergmann , Alexander Ruffani , Luisa DeCola
IPC分类号： A61K9/51 , A61K49/00 , A61K51/12 , A61K47/48 , A61K31/519 , A61K31/65 , A61K33/24 , A61K31/282 , A61K31/513 , C07F7/08 , A61K31/337
CPC分类号： A61K9/5123 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/65 , A61K33/24 , A61K47/54 , A61K47/6923 , A61K49/0093 , A61K51/1244 , B82Y30/00 , C01B33/02 , C01B33/027 , C01P2002/82 , C01P2002/84 , C01P2004/04 , C01P2004/64 , C01P2004/84 , C01P2006/42 , C07F7/0827 , C09C1/28 , C09C1/3063 , Y10T428/2982
摘要： The present invention is related to silicon nanoparticles, a pharmaceutical composition comprising silicon nanoparticles, a method for synthesis of the silicon nanoparticles and their use for in vivo diagnostics, visualization of drug delivery or staining of cells, biological processes or pathways. The silicon nanoparticles are characterised that they comprise a silicon core of a size of 1 to 10 nm and are terminated with allylamine or poly(allylamine) comprising up to 10 allylamine groups.
摘要翻译：本发明涉及硅纳米颗粒，包含硅纳米颗粒的药物组合物，用于合成硅纳米颗粒的方法及其用于体内诊断，药物递送或细胞染色的可视化，生物过程或途径的用途。硅纳米颗粒的特征在于它们包含大小为1至10nm的硅芯，并以含有至多10个烯丙胺基团的烯丙胺或聚（烯丙胺）封端。

45. 发明申请

US20130258319A1 NEEDLE PROBE FOR ANALYSIS OF MULTIPHASE FLOWS, PRODUCTION AND USE OF NEEDLE PROBE 审中-公开
标题翻译：用于多相流动分析的针头探针，针刺探头的生产和使用
公开(公告)号：US20130258319A1
公开(公告)日：2013-10-03
申请号：US13855292
申请日：2013-04-02
申请人： HELMHOLTZ-ZENTRUM DRESDEN - ROSSENDORF E.V.
发明人： Eckart SCHLEICHER , Stefan KAYSER
IPC分类号： G01R1/067 , G01N21/85
CPC分类号： G01R1/06711 , G01N21/85 , G01N21/8507 , G01N27/07
摘要： A triaxial constructed needle probe for reliable differentiation of multiphase media, comprises a probe body having a central light conductor having a metallic surface and a distal end of which is to be inserted in the medium, a first electrically insulating sheath disposed around the optical fiber, a hollow cylindrical shield electrode arranged around the first insulating sheath, a second electrically insulating sheath arranged around the shield electrode, and a hollow cylindrical reference electrode arranged around the second insulating sheath, as well as a measuring circuit for measuring the optical refractive index and electrical conductivity of the medium.
摘要翻译：一种用于多相介质可靠分化的三轴构造的针探针，包括具有中心导体的探针体，所述中心导体具有金属表面并且其远端将被插入到介质中，围绕光纤设置的第一电绝缘护套，布置在第一绝缘护套周围的中空圆柱形屏蔽电极，围绕屏蔽电极布置的第二电绝缘护套和布置在第二绝缘护套周围的中空圆柱形参考电极，以及用于测量光学折射率和电气的测量电路介质的电导率。

46. 发明公开

US20230167879A1 TWO-AXIS ROTATOR 审中-公开
公开(公告)号：US20230167879A1
公开(公告)日：2023-06-01
申请号：US17905338
申请日：2021-03-03
申请人： HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF E.V.
发明人： Stefan Findeisen
IPC分类号： F16H1/22 , F16M11/12 , F16M11/18
CPC分类号： F16H1/225 , F16M11/12 , F16M11/18
摘要： The invention relates to a two-axis rotator for producing a rotation about two orthogonal spatial axes, and to a handling device comprising a two-axis rotator of this kind. The two-axis rotator for producing a rotation about two mutually orthogonal rotational axes comprises a main body, a first rotor and a second rotor, wherein the first rotor is mounted on or in the main body so as to be able to rotate about a first rotational axis, and the second rotor is mounted on or in the first rotor so as to be able to rotate about a second rotational axis, and wherein the first rotor has a first drive and the second rotor has a second drive, and the first drive and the second drive can be driven independently of one another.

47. 发明授权

US11353460B2 L2A5 antibody or functional fragment thereof against tumour antigens 有权
公开(公告)号：US11353460B2
公开(公告)日：2022-06-07
申请号：US16964900
申请日：2019-01-17
申请人： UNIVERSIDADE NOVA DE LISBOA , INSTITUTO PORTUGUÊS DE ONCOLOGIA DO PORTO FG, EPE , HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF—INSTITUTE OF RADIOPHARMACEUTICAL CANCER RESEARCH
发明人： Paula Alexandra Quintela Videira , Carlos Manuel Mendes Novo , Liliana Raquel Rodrigues Loureiro , Mylène Adelaide do Rosário Carrascal , José Alexandre Ribeiro de Castro Ferreira , Maria Angelina de Sá Palma , Lúcio Lara Santos , Luís Carlos Oliveira Lima , Wengang Chai , Michael Bachmann
IPC分类号： G01N33/574 , A61P35/00 , C07K16/30
摘要： This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer.
The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.

48. 发明授权

US11156574B2 Apparatus for characterizing the electrical resistance of a measurement object 有权
公开(公告)号：US11156574B2
公开(公告)日：2021-10-26
申请号：US16483937
申请日：2018-03-01
申请人： Helmholtz-Zentrum Dresden-Rossendorf E.V.
发明人： Tobias Kosub , Denys Makarov
IPC分类号： G01N27/04 , G01N27/92
摘要： The invention relates to a measuring apparatus for characterizing the electrical resistance of a measurement object, comprising an electric energy source having two poles, a voltage measuring device having two measuring inputs, four connecting contacts for the connection of four contact electrodes, and a switching device for the variable electrical pairwise connection of each one of the poles and measuring inputs to each one of the connecting contacts, forming different wiring configurations, wherein the measuring device is configured to carry out at least two measuring sequences with different wiring configurations and to determine the series resistance of the measurement object by incorporating the current and voltage signals acquired in these wiring configurations.

49. 发明申请

US20210131747A1 Heat Exchanger 有权
公开(公告)号：US20210131747A1
公开(公告)日：2021-05-06
申请号：US16638786
申请日：2018-08-03
申请人： Helmholtz-Zentrum Dresden - Rossendorf e.V. , Technische Universität Dresden
发明人： Sebastian Unger , Uwe Hampel
IPC分类号： F28F1/02 , F28F1/28
摘要： The invention relates to a heat exchanger having at least one partition and surface elements which project from at least one side of the partition and which enlarge the surface of the partition and around which a fluid can flow. The problem addressed by the present invention is that of proposing heat exchangers of low mass with high thermal transmission capacity. This problem is solved by means of a heat exchanger in which the surface elements are formed so as to project in the manner of fins from the partition, and the surface elements have reinforcement beads, wherein the reinforcement beads extend as far as the partition.

50. 发明授权

US09812640B2 Complementary resistance switch, contact-connected polycrystalline piezo- or ferroelectric thin-film layer, method for encrypting a bit sequence 有权
公开(公告)号：US09812640B2
公开(公告)日：2017-11-07
申请号：US14800785
申请日：2015-07-16
申请人： Helmholtz-Zentrum Dresden-Rossendorf e. V.
发明人： Tiangui You , Heidemarie Schmidt , Nan Du , Danilo Buerger , Ilona Skorupa , Niveditha Manjunath
IPC分类号： H04L9/00 , H01L45/00 , H01L31/0749 , H01L27/24 , G09C1/00 , H04L9/06 , H03K19/08 , G11C13/00
CPC分类号： H01L45/147 , G09C1/00 , G11C13/0007 , H01L27/2472 , H01L31/0749 , H01L45/065 , H01L45/08 , H01L45/1233 , H01L45/1641 , H01L45/165 , H03K19/08 , H04L9/00 , H04L9/065 , H04L2209/12 , Y02E10/541
摘要： Disclosed is a complementary resistor switch (3) comprising two outer contacts, between which two piezo- or ferroelectric layers (11a and 11b) having an inner common contact are situated. At least one region (11′, 11″) of the layers is modified, either the outer contacts are rectifying (S) and the inner contact is non-rectifying (0), or vice versa, the modified regions are formed at the rectifying contacts, the layers have different strain-dependent structural phases with different band gaps and/or different polarization charges, and the electrical conductivity of the layers is different. Also disclosed are a connectable resistor structure having at least one Schottky contact at two adjoining piezo- or ferroelectric layers, a polycrystalline piezo- or ferroelectric layer comprising modified crystallites, and a method and circuits for encrypting and decrypting a bit sequence.

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