专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

US20060079555A1 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof 审中-公开
标题翻译：二芳基亚甲基哌啶衍生物，其制备方法及用途
公开(公告)号：US20060079555A1
公开(公告)日：2006-04-13
申请号：US10550661
申请日：2004-04-01
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： C07D211/32 , A61K31/445
CPC分类号： C07D417/12 , C07D211/70
摘要： Compounds of general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, m and n are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译：制备其中R 1，R 2，R 3，R 4，R 5，R 6，R 7，m和n如本说明书中所定义的通式（I）的化合物及其盐，对映异构体和包含该化合物的药物组合物。它们可用于治疗，特别是治疗疼痛。

42. 发明授权

US06442714B1 Web-based integrated testing and reporting system 有权
标题翻译：基于Web的综合测试和报告系统
公开(公告)号：US06442714B1
公开(公告)日：2002-08-27
申请号：US09271016
申请日：1999-03-17
申请人： Andrew Griffin , Daniel Paul Teeter , Shannon Rae Smith
发明人： Andrew Griffin , Daniel Paul Teeter , Shannon Rae Smith
IPC分类号： G06F1100
CPC分类号： G06F11/2294
摘要： A centralized product testing system and method for its operation are disclosed. The system has a test application server that communicates with remote users as a web-based application. Equipment testers login to the system through their web browser. They can then run tests while viewing instructions for the test and entering results in dynamically-generated web browser forms tailored to their test. Completed forms (including files generated by test equipment tied to a tester's computer) can then be uploaded to the testing system. The testing system relates the test data to the product under test and stores the data in a relational database. The test data can then be used to dynamically generate preliminary or formal test reports for compliance and other purposes. The system has many benefits. For example, because test procedures, data, and report forms are all centrally stored, they can be reliably maintained and quickly updated. Each user need only have a working web browser in order to be walked through a complicated testing process. The system reduces errors and greatly decreases effort as compared to a manual system where each tester must create report documents individually and manually.
摘要翻译：公开了一种集中的产品测试系统及其操作方法。该系统具有与远程用户作为基于Web的应用程序进行通信的测试应用程序服务器。设备测试人员通过网络浏览器登录系统。然后，他们可以在查看测试指令并输入结果时运行测试，动态生成针对其测试的Web浏览器表单。完成的表格（包括与测试人员计算机相连的测试设备产生的文件）可以上传到测试系统。测试系统将测试数据与被测产品相关联，并将数据存储在关系数据库中。然后，测试数据可用于动态生成初步或正式的测试报告以实现合规性和其他目的。系统具有许多优点。例如，由于测试程序，数据和报表单都是集中存储的，所以可以可靠地维护并快速更新。每个用户只需要一个工作的Web浏览器，以便通过一个复杂的测试过程。与手动系统相比，系统可以减少错误并大大降低工作量，每个测试人员必须单独和手动创建报告文档。

43. 发明申请

US20100130477A1 Spirocyclobutyl Piperidine Derivatives 审中-公开
标题翻译：螺环丁基哌啶衍生物
公开(公告)号：US20100130477A1
公开(公告)日：2010-05-27
申请号：US12623585
申请日：2009-11-23
申请人： Peter Bernstein , Dean Brown , Andrew Griffin , Maxime C. Tremblay , Steven Wesolowski
发明人： Peter Bernstein , Dean Brown , Andrew Griffin , Maxime C. Tremblay , Steven Wesolowski
IPC分类号： A61K31/551 , C07D487/00 , C07D223/14 , A61K31/497 , A61P25/28 , A61P25/18 , A61P25/22 , A61P25/00 , A61P3/04
CPC分类号： C07D401/10 , C07D221/20 , C07D401/04 , C07D401/06 , C07D401/14
摘要： Disclosed herein is at least one spirocyclobutyl piperidine derivative, at least one pharmaceutical composition comprising at least one spirocyclobutyl piperidine derivative disclosed herein, and at least one method of using at least one spirocyclobutyl piperidine derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
摘要翻译：本文公开了至少一种螺环丁基哌啶衍生物，至少一种包含本文公开的至少一种螺环丁基哌啶衍生物的药物组合物和至少一种使用本文公开的至少一种螺环丁基哌啶衍生物来治疗至少一种组胺H3受体相关病症随之而来。

44. 发明授权

US07396834B2 4(Phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders 失效
标题翻译： 4（苯基 - 哌嗪基 - 甲基）苯甲酰胺衍生物及其用于治疗疼痛或胃肠道疾病的用途
公开(公告)号：US07396834B2
公开(公告)日：2008-07-08
申请号：US10533744
申请日：2003-11-05
申请人： William Brown , Andrew Griffin , Niklas Plobeck , Christopher Walpole
发明人： William Brown , Andrew Griffin , Niklas Plobeck , Christopher Walpole
IPC分类号： A61K31/495 , A61K31/496 , C07D295/155 , C07D307/52
CPC分类号： C07D295/155 , C07D307/52
摘要： Compounds of general formula: wherein R1 and R2 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译：制备其中R 1和R 2的化合物如说明书中所定义，以及其盐，对映异构体和包含该化合物的药物组合物。它们可用于治疗，特别是治疗疼痛。

45. 发明申请

US20070293502A1 Diarylmethyl Piperazine Derivatives, Preparations Thereof and Uses Thereof 审中-公开
标题翻译：二芳基甲基哌嗪衍生物，其制备及其用途
公开(公告)号：US20070293502A1
公开(公告)日：2007-12-20
申请号：US10596851
申请日：2005-01-05
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： C07D295/155 , A61K31/495 , A61P25/04 , A61P25/22
CPC分类号： C07D295/155
摘要： Compounds of formula: wherein R1, R2 and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译：其中R 1，R 2和R 3的化合物如说明书中所定义，以及其盐，对映体和药物制备包括这些化合物的组合物。它们可用于治疗，特别是治疗疼痛。

46. 发明授权

US07253173B2 4(Phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain of gastrointestinal disorders 失效
标题翻译： 4（苯基 - 哌嗪基 - 甲基）苯甲酰胺衍生物及其用于治疗胃肠道疾病的疼痛的用途
公开(公告)号：US07253173B2
公开(公告)日：2007-08-07
申请号：US10533654
申请日：2003-11-05
申请人： William Brown , Andrew Griffin , Paul Jones , Daniel Pagé , Niklas Plobeck , Christopher Walpole
发明人： William Brown , Andrew Griffin , Paul Jones , Daniel Pagé , Niklas Plobeck , Christopher Walpole
IPC分类号： C07D24/04 , A61K31/4965 , A61K31/497 , A61P25/04
CPC分类号： C07D213/38 , C07D215/12 , C07D233/64 , C07D277/28 , C07D295/155 , C07D307/52 , C07D333/20
摘要： Compounds of general formula (I) wherein R1, R2 and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain
摘要翻译：其中R 1，R 2和R 3的通式（I）的化合物如说明书中所定义，以及盐，对映异构体并且制备包含该化合物的药物组合物。它们可用于治疗，特别是治疗疼痛

47. 发明申请

US20070099957A1 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof 审中-公开
标题翻译：二芳基亚甲基哌啶衍生物，其制备方法及用途
公开(公告)号：US20070099957A1
公开(公告)日：2007-05-03
申请号：US10555980
申请日：2004-05-13
申请人： William Brown , Andrew Griffin , Shujuan Jin
发明人： William Brown , Andrew Griffin , Shujuan Jin
IPC分类号： A61K31/454 , A61K31/445 , C07D211/26 , C07D401/02
CPC分类号： C07D211/70 , C07D401/06 , C07D417/06
摘要： Compounds of formula: (I) wherein R1, R2, R3, R4 and R7 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译：式（I）的化合物，其中R 1，R 2，R 3，R 4和R 4，本说明书中定义的，以及其盐，对映异构体和包含该化合物的药物组合物。它们可用于治疗，特别是治疗疼痛。

48. 发明申请

US20070066655A1 Diarylmethylidene piperidine derivatives and their use as delta opiod receptor agonists 审中-公开
标题翻译：二芳基亚甲基哌啶衍生物及其作为δ阿片受体激动剂的用途
公开(公告)号：US20070066655A1
公开(公告)日：2007-03-22
申请号：US10555981
申请日：2004-05-13
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： A61K31/453 , A61K31/452 , C07D409/02 , C07D405/02
CPC分类号： C07D211/70 , C07D401/06 , C07D405/06 , C07D409/06 , C07D417/06
摘要： Compounds of general formula: (Formula (I)) wherein R1, R2, R3, R4 and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain and anxiety.
摘要翻译：通式为（式（I））的化合物，其中R 1，R 2，R 3，R 4， >和R 5如本说明书中所定义，以及其盐，对映体和包含该化合物的药物组合物。它们可用于治疗，特别是治疗疼痛和焦虑症。

49. 发明申请

US20060287361A1 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof as opoid receptors ligands 审中-公开
标题翻译：二芳基亚甲基哌啶衍生物，其制备方法及其用作opoid受体配体
公开(公告)号：US20060287361A1
公开(公告)日：2006-12-21
申请号：US10557069
申请日：2004-05-13
申请人： William Brown , Andrew Griffin
发明人： William Brown , Andrew Griffin
IPC分类号： A61K31/452 , C07D405/02 , C07D211/26 , A61K31/445
CPC分类号： C07D405/06 , C07D211/70 , C07D411/06
摘要： Compounds of general formula: (I) wherein R1, R2, R3 and A are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the treatment of pain and anxiety.
摘要翻译：通式（I）的化合物，其中R 1，R 2，R 3和A如说明书中所定义，以及盐，其对映异构体和包含该化合物的药物组合物。它们可用于治疗，特别是治疗疼痛和焦虑症。

50. 发明申请

US20060154964A1 Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof 审中-公开
标题翻译：二芳基亚甲基哌啶衍生物，其制备方法及用途
公开(公告)号：US20060154964A1
公开(公告)日：2006-07-13
申请号：US10541522
申请日：2004-01-13
申请人： William Brown , Andrew Griffin , Christopher Walpole
发明人： William Brown , Andrew Griffin , Christopher Walpole
IPC分类号： A61K31/4545 , A61K31/454 , C07D413/02 , C07D401/02
CPC分类号： C07D211/70 , C07D401/06 , C07D405/06 , C07D409/06 , C07D417/06
摘要： Compounds of general formula: (formula I) wherein R1, R2, R3, R4, and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译：通式为（式I）的化合物，其中R 1，R 2，R 3，R 4，和R 5如本说明书中所定义，以及其盐，对映异构体和包含该化合物的药物组合物。它们可用于治疗，特别是治疗疼痛。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式