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41. 发明授权

US08785619B1 Nucleosides and oligonucleotides for studies on reversal of cytotoxic and mutagenic damage of DNA potential diagnostics tools 有权
标题翻译：用于DNA潜力诊断工具逆转细胞毒性和诱变性损伤研究的核苷和寡核苷酸
公开(公告)号：US08785619B1
公开(公告)日：2014-07-22
申请号：US11018567
申请日：2004-12-20
申请人： Sant K. Srivastav , Suresh C. Srivastava , Satya P Bajpai
发明人： Sant K. Srivastav , Suresh C. Srivastava , Satya P Bajpai
IPC分类号： C07H19/20 , C07H19/04 , C07H21/00
CPC分类号： C07H21/00 , C07H19/06 , C07H19/16 , Y02P20/55
摘要： This invention relates to n-alkylated synthetic nucleosides and phosphoramidites of high regio-specific purity and stability and for selective deprotection of the protecting group in oligonucleotides for the purpose of synthesis of high purity selectively n-alkylated sequence specific DNA and RNA. Such oligonucleotides are useful for study of mechanism of cytotoxic and mutagenic DNA damage, detection and reversal of cellular cytotoxic and mutagenic damages that occurs from the incorporation of methylated nucleosides, the corresponding phosphates and triphosphates and their precursors, via de novo DNA synthesis. The reagents could be extremely valuable tools as diagnostics and mutagenic reversal reagents. The present invention describes N-1-nitrogen alkylated purine and N-3 nitrogen alkylated pyrimidines with appropriate nucleobase amino protection, which are selectively deprotected with minimal migration of the alkyl substituent under the condition which are required for synthesizing high purity regiospecific N-1 and N-3 nitrogen alkylated oligonucleotides. A novel process has been developed to synthesize N-3 nitrogen alkylated cytidine.
摘要翻译：本发明涉及具有高区域特异性纯度和稳定性的N-烷基化合成核苷和亚磷酰胺，并且为了合成高纯度选择性N-烷基化序列特异性DNA和RNA的目的，寡核苷酸中保护基的选择性脱保护。这种寡核苷酸可用于研究通过从头DNA合成从引入甲基化核苷，相应的磷酸酯和三磷酸酯及其前体而发生的细胞毒性和诱变性DNA损伤，检测和逆转细胞毒性和诱变性损伤的机制。这些试剂可以作为诊断和诱变反转试剂非常有价值的工具。本发明描述了具有适当核碱基氨基保护的N-1-氮烷基化嘌呤和N-3氮烷基化嘧啶，其在合成高纯度区域特异性N-1所需的条件下以极少的烷基取代基迁移选择性脱保护， N-3氮烷基化寡核苷酸。已经开发了一种合成N-3氮烷基化胞苷的新方法。

42. 发明授权

US11613679B2 Adhesive composition, adhesive comprising same, and manufacturing method therefor 有权
公开(公告)号：US11613679B2
公开(公告)日：2023-03-28
申请号：US16638401
申请日：2018-08-22
申请人： KOLON INDUSTRIES, INC. , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
发明人： Hong Gu Hwang , Ick Kyung Sung , Du Hwan Kim , Jung Seok Hahn , Haeshin Lee , Dai Heon Lee
IPC分类号： C09J129/04 , A61K47/32 , A61K47/22 , C09J11/08
摘要： The present invention relates to an adhesive composition comprising a polyvinyl alcohol and a water-soluble polyphenol compound, to an adhesive comprising the same, and to a manufacturing method therefor and, more specifically, to an adhesive composition, which has little toxicity, can adhere even without a curing process unlike a conventional adhesive, enables the manufacturing of a gel by hydrogen binding characteristics between the polyvinyl alcohol compound and the water-soluble polyphenol compound, and retains adhesive properties in water.

43. 发明授权

US11585739B2 Method for extracting nucleic acid using cartridge 有权
公开(公告)号：US11585739B2
公开(公告)日：2023-02-21
申请号：US16956589
申请日：2018-12-20
申请人： SD BIOSENSOR, INC.
发明人： Young Shik Cho , Hyo Guen Lee , Hae Joon Park , Sun Young Lee , Kwan Hun Lim , In Ae Kim , Jae Young Kim , Hyo Lim Park , Dong Hun Kim
IPC分类号： G01N1/40 , G01N1/34 , G01N35/08 , G01N35/02 , G01N35/10 , G01N35/00 , G01N35/04
摘要： There is provided a nucleic acid extraction method using a cartridge comprising: (a) a driving part of a nucleic acid extraction device is connected to a control rod module disposed in an inner space of the upper body of a piston and a rotation control module coupled to the lower body of the piston; (b) driving the rotation control module and the control rod module, sequentially sucking sample and reagents from the plurality of chambers separated from each other into an interior space, and discharging the mixture of the interior space into the chamber of the cartridge; and (c) driving the rotation control module and the control rod module to suck the reagent inside the master mix bead chamber of the cartridge into the interior space of the piston upper body and then discharge the mixed reagent to a nucleic acid amplification module.

44. 发明授权

US11567480B2 Integrated management method and system for heterogeneous logistics automation equipment 有权
公开(公告)号：US11567480B2
公开(公告)日：2023-01-31
申请号：US17627924
申请日：2020-08-12
申请人： CJ LOGISTICS CORPORATION
发明人： Do Hun Kwon , Hoi Kwon Moon , Sa Yeok Min , Byung Gyo Suh
IPC分类号： G05B19/418 , G06Q10/08 , H04L67/12 , G05B19/048 , H04L69/00
摘要： The present invention relates to an integrated management system for heterogeneous logistics automation equipment, including: an equipment standard protocol server adapted to receive commands from a plurality of warehouse management systems (WMS), to check equipment standard protocol identification (ESP ID) matching the received commands, and to produce work information in the form of telegram: a plurality of warehouse control systems (WCS) adapted to control the logistics automation equipment through the work information produced from the equipment standard protocol server; and a plurality of equipment control systems (ECS) adapted to receive the work information from the plurality of warehouse control systems (WCS) to control the logistics automation equipment.

45. 发明授权

US11560128B2 Electronic brake system 有权
公开(公告)号：US11560128B2
公开(公告)日：2023-01-24
申请号：US17271211
申请日：2019-08-27
申请人： HL MANDO CORPORATION
发明人： Sang Hoon Kim , Seong Ho Choi
IPC分类号： B60T13/66 , B60T7/04 , B60T13/74 , B60T17/22
摘要： The present disclosure relates to a control method of a brake system including a reservoir in which oil is stored, wherein the control method includes detecting a first level of a liquid level of oil stored in the reservoir, detecting a second level of the liquid level of oil stored in the reservoir, determining a decrease trend of an oil amount stored in the reservoir based on a time point when the first level is detected and a time point when the second level is detected, and limiting at least one additional function based on the decrease trend of the oil amount.

46. 发明授权

US11549876B2 Apparatus and method for determining chemical input 有权
公开(公告)号：US11549876B2
公开(公告)日：2023-01-10
申请号：US15700988
申请日：2017-09-11
申请人： DOOSAN ENERBILITY CO., LTD.
发明人： Seongjoon Kim , Jungwon Park , Youngkyu Lee
IPC分类号： G01N15/06 , C02F1/00 , G01N25/00 , C02F1/52 , C02F1/24 , C02F1/66 , C02F103/08
摘要： An apparatus and method for determining an amount of chemical input, and more particularly to an apparatus and method for determining the amount of a chemical to be added, which is necessary to achieve target water quality, wherein a required chemical concentration can be accurately calculated based on the temperature of the water and the target turbidity of the water includes an information-receiving unit configured to receive at least one of environmental information, chemical information, and water-quality information of the water present in a specific area and a chemical input determination unit configured to derive a multiple regression equation based on the received environmental information, chemical information, and water-quality information and to determine the future input of a chemical that is added to satisfy a target turbidity of the water present in the specific area based on the multiple regression equation.

47. 发明授权

US11543131B2 Nozzle assembly, combustor, and gas turbine having same 有权
公开(公告)号：US11543131B2
公开(公告)日：2023-01-03
申请号：US17548498
申请日：2021-12-11
申请人： DOOSAN ENERBILITY CO., LTD
发明人： Han Jin Jeong
IPC分类号： F23R3/28 , F23R3/14 , F23R3/16
摘要： A nozzle assembly for injecting fuel and compressed air into a combustion chamber of a gas turbine combustor is provided. The nozzle assembly includes a nozzle body disposed in the combustor and having a coolant outlet on one end of which an inside of the nozzle body communicates with the combustion chamber, a spray nozzle disposed in the nozzle body and including a plurality of first nozzle tubes each having a first flow path formed therein to allow combustion air to flow into the combustion chamber and a fuel hole formed to supply fuel, and a second nozzle tube having through-holes to allow the first nozzle tubes to pass therethrough and a second flow path formed to supply fuel, and a diaphragm disposed inside of the nozzle body and including a plurality of coolant flow holes through which a coolant supplied to the nozzle body is supplied towards one end of the nozzle body and a plurality of tube holes through which the first nozzle tubes pass.

48. 发明授权

US11541401B2 Dust collecting tower apparatus 有权
公开(公告)号：US11541401B2
公开(公告)日：2023-01-03
申请号：US16855942
申请日：2020-04-22
申请人： DOOSAN ENERBILITY CO., LTD.
发明人： Jin Woon Lee , Sang Rin Lee , Jae Dong Hwang , Sang Chul Moon
IPC分类号： B03C3/78 , B03C3/41 , B03C3/47 , B03C3/66 , B03C3/88 , B03C3/82 , B03C3/02 , G09F9/33
摘要： Disclosed herein is a dust collecting tower apparatus that includes a housing having an inlet, into which gas is introduced, and an outlet from which the gas is discharged, and a collection module disposed in the housing and configured to collect particulates with a corona discharge. The collection module includes a plurality of discharge electrodes, to which a voltage is applied, a plurality of collection electrodes disposed between the respective discharge electrodes, where the collection electrodes is grounded, and a first setting beam having a plurality of lower slots into which the discharge electrodes are inserted. The apparatus further includes a washing water feeder configured to spray washing water to the collection module.

49. 发明授权

US11525405B2 Turbine apparatus 有权
公开(公告)号：US11525405B2
公开(公告)日：2022-12-13
申请号：US17492572
申请日：2021-10-02
申请人： DOOSAN ENERBILITY CO., LTD
发明人： Jin Woong Ha , GeonHwan Cho
IPC分类号： F01D11/00 , F02C7/28 , F02C3/04
摘要： Disclosed is a turbine apparatus. The turbine apparatus includes s stator, a rotor rotatably installed in the stator, and a sealing mechanism provided to prevent a working fluid from leaking between the stator and the rotor. The sealing mechanism is configured such that when the rotor is stopped, the sealing mechanism is brought into contact with the rotor, and when the rotor is rotated, the sealing mechanism is formed to be spaced from the rotor by a predetermined gap.

50. 发明授权

US11499438B2 Turbine vane, and turbine and gas turbine including the same 有权
公开(公告)号：US11499438B2
公开(公告)日：2022-11-15
申请号：US17684733
申请日：2022-03-02
申请人： DOOSAN ENERBILITY CO., LTD.
发明人： Hyun Woo Joo
IPC分类号： F01D9/06 , F01D9/04 , F01D9/02 , F01D5/18 , F01D25/12
摘要： A turbine vane, a turbine, and a gas turbine capable of reducing thermal stress are provided. The turbine vane may include an airfoil including a leading edge and a trailing edge, an inner shroud disposed at one end of the airfoil to support the airfoil, an outer shroud disposed at the other end of the airfoil to support the airfoil and configured to face the inner shroud, a first cooling passage and a second cooling passage configured to extend in a height direction thereof, and a first passage bending part configured to connect the first cooling passage and the second cooling passage, and the first passage bending part is positioned inside the inner shroud or the outer shroud.

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