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41. 发明授权

US4596707A Babesia parasite antigen useful in vaccine and diagnostic reagent 失效
标题翻译：用于疫苗和诊断试剂的巴贝虫寄生虫抗原
公开(公告)号：US4596707A
公开(公告)日：1986-06-24
申请号：US130481
申请日：1980-03-31
申请人： Miodrag Ristic , Carlos Arellano
发明人： Miodrag Ristic , Carlos Arellano
IPC分类号： A61K39/018 , G01N33/569 , A61K39/00
CPC分类号： A61K39/018 , G01N33/56905
摘要： Soluble antigen, specific for Babesia parasites, is isolated from growth media of Babesia-infected erythrocytes in cell culture and characterized, inter alia, by its ability to inhibit the capacity of specific Babesia serum antibodies to neutralize infectivity of Babesia merozoites in vitro. Antigen preparations provide immunologically active components useful for vaccination of animals against infection by Babesia parasites and may be employed in the preparation of diagnostic reagents.
摘要翻译：特异于巴贝虫寄生虫的可溶性抗原从细胞培养物中的巴贝虫感染的红细胞的生长培养基中分离出来，其特征在于其能够抑制特异性巴贝虫血清抗体在体外中和巴贝虫裂殖子的感染性的能力。抗原制剂提供免疫活性成分，用于疫苗接种疫苗以抵抗巴贝虫寄生虫的感染，并可用于制备诊断试剂。

42. 发明授权

US4535061A Bacteria capable of dissimilation of environmentally persistent chemical compounds 失效
标题翻译：能够区分环保化学化合物的细菌
公开(公告)号：US4535061A
公开(公告)日：1985-08-13
申请号：US334519
申请日：1981-12-28
申请人： Ananda M. Chakrabarty , Scott T. Kellogg
发明人： Ananda M. Chakrabarty , Scott T. Kellogg
IPC分类号： A62D3/00 , A62D3/02 , B09C1/10 , C02F3/34 , C12N15/52 , C12N1/20 , C02F3/00 , C12N15/00
CPC分类号： A62D3/02 , B09C1/10 , C02F3/34 , C12N15/52 , C12R1/06 , C12R1/38 , A62D2101/04 , A62D2101/20 , Y10S435/83 , Y10S435/874
摘要： Plasmid-assisted molecular breeding procedures for generating pure and mixed cultures of microorganisms capable of dissimilating environmentally persistent chemical compounds. Continuously cultured growth of microorganisms is carried out in the presence of a source of DNA plasmids participative in dissimilation of compounds structurally analogous to the persistent compounds and under chemostatic conditions including gradually increasing concentrations of the persistent compound. Novel microorganism products of the procedures include a mixed Arthrobacter and Pseudomonas culture, A.T.C.C. 39028, capable of total degradation of mixed polychlorinated biphenyls (e.g., Arochlor 1221) and a pure culture of Pseudomonas cepacia, A.T.C.C. 39027, which can utilize 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) as its sole carbon source. Disclosed also are procedures for using pure and mixed cultures of the invention in degrading persistent compounds contaminating soil and aqueous environments.
摘要翻译：用于产生纯化和混合的微生物培养物的质粒辅助分子育种程序，能够使环境持久化学化合物异化。持续培养微生物的生长是在DNA质粒来源的情况下进行的，所述DNA质粒来源于结构类似于持久性化合物的化合物的异构化，并且在化学条件下，包括持续化合物的逐渐增加的浓度。该方法的新型微生物产物包括混合的节杆菌和假单胞菌培养物A.T.C.C. 39028，能够使混合的多氯联苯（例如，Arochlor 1221）和纯洋葱假单胞菌（A.C.C.C）的纯培养物完全降解。 39027，其可以利用2,4,5-三氯苯氧基乙酸（2,4,5-T）作为其唯一的碳源。还公开了使用本发明的纯和混合培养物降解污染土壤和水环境的持久化合物的程序。

43. 发明授权

US4398392A System for separation of water from the working fluid in low temperature difference power plants 失效
标题翻译：低温差热发电厂工作液体水分离系统
公开(公告)号：US4398392A
公开(公告)日：1983-08-16
申请号：US300988
申请日：1981-09-10
申请人： Ejup N. Ganic
发明人： Ejup N. Ganic
IPC分类号： F01K25/10
CPC分类号： F01K25/106
摘要： Apparatus for separating an undesired foreign fluid, such as water, from the working fluid, such as ammonia, in a low temperature difference power plant which includes an evaporator and a condensor. A flash separator unit vaporizes the working fluid and separates it from the undesired foreign fluid. The vaporized working fluid is condensed in the condensor. The undesired foreign fluid is accumulated in the evaporator from which it can then be removed. In an alternative embodiment, the separated foreign fluid and liquid ammonia collected in the flash separator unit are not returned to the evaporator, but instead, are coupled back into the flash separator where the separated foreign fluid accumulates so that at the end of the separation process, the undesired foreign fluid can be removed from the flash separator. An alternative embodiment enables the power generating system to continue in operation, although with a decreased capacity during the fluid separation process.
摘要翻译：用于在包括蒸发器和冷凝器的低温差动力装置中从工作流体（例如氨）中分离不期望的外来流体（例如水）的装置。闪蒸分离器单元蒸发工作流体并将其与不期望的外来流体分离。蒸发的工作流体在冷凝器中冷凝。不期望的外来流体积聚在蒸发器中，然后从蒸发器中除去。在替代实施例中，收集在闪蒸分离器单元中的分离的外来流体和液态氨不会返回到蒸发器，而是返回到闪蒸分离器中，在该分离器中分离的外来流体积聚，使得在分离过程结束时，可以从闪光分离器中除去不需要的外来流体。尽管在流体分离过程中具有降低的容量，但是替代实施例使发电系统能够继续运行。

44. 发明授权

US4328125A Heterogeneous anionic transition metal catalysts 失效
标题翻译：非均相阴离子过渡金属催化剂
公开(公告)号：US4328125A
公开(公告)日：1982-05-04
申请号：US192793
申请日：1980-10-01
申请人： Russell S. Drago , Anton El A'mma
发明人： Russell S. Drago , Anton El A'mma
IPC分类号： B01J31/08 , B01J31/16 , B01J31/20 , C07C45/50 , C07C51/12 , C08F8/42
CPC分类号： B01J31/165 , B01J31/08 , B01J31/20 , C07C45/50 , C07C51/12 , B01J2231/321 , B01J2531/822
摘要： Novel heterogeneous catalysts consist essentially of an anion exchange resin to which is bound ionically an anionic metal carbonyl species having the general formula M.sub.n (CO).sub.m (X).sub.p.sup.z- where M is a transition metal such as for example rhodium, cobalt, ruthenium, osmium, iridium, or iron; X is an anion, for example halide, hydride, or alkyl; n ranges from 1 to 12; m ranges from 1 to 34; p ranges from 0 to 2n+1; and z is an integer charge ranging from 1 to 5. The catalyst in which M is rhodium, m=2, p=2, n=1, and z=1 is highly effective for the carbonylation of alcohols to acids and esters. Many of these anionic species have utility in the hydroformylation of olefins.
摘要翻译：新型非均相催化剂基本上由阴离子交换树脂组成，其中离子性地结合具有通式Mn（CO）m（X）pz-的阴离子金属羰基物质，其中M是过渡金属，例如铑，钴，钌，锇，铱或铁; X是阴离子，例如卤化物，氢化物或烷基; n范围从1到12; m范围从1到34; p范围从0到2n + 1; 并且z是1至5的整数.M是铑，m = 2，p = 2，n = 1和z = 1的催化剂对于将醇羰基化成酸和酯是非常有效的。许多这些阴离子物质在烯烃的加氢甲酰化中具有效用。

45. 发明授权

US4307191A Propagation of babesia parasites 失效
标题翻译：宝贝寄生虫的传播
公开(公告)号：US4307191A
公开(公告)日：1981-12-22
申请号：US130482
申请日：1980-03-31
申请人： Miodrag Ristic , Michael G. Levy
发明人： Miodrag Ristic , Michael G. Levy
IPC分类号： A61K39/018 , C12N1/10 , C12Q1/18
CPC分类号： A61K39/018 , C12N1/10 , C12Q1/18 , Y10S435/947
摘要： A method for quantitative propagation of hemotropic parasites, especially Babesia parasites, in vitro, Babesia-infected erythrocyte cultures are incubated in an environment of enhanced carbon dioxide tension wherein the culture medium overlay provides a barrier to oxygen transmission such that cellular hemoglobin is essentially maintained in its deoxy state. By varying environmental carbon dioxide tension, merozoite stages of the parasite are selectively reversibly induced to migration between residence in host cells or culture medium, rendering possible the isolation of infective antigenic merozoites in large quantities. Specific Babesia antigen is harvested in large quantity from the in vitro culture medium.
摘要翻译：血液寄生虫，特别是巴贝虫寄生虫，体外，巴贝虫感染的红细胞培养物的定量增殖的方法在增强的二氧化碳张力的环境中温育，其中培养基覆盖物提供对氧传递的屏障，使得细胞血红蛋白基本上保持在其脱氧状态。通过改变环境二氧化碳的张力，寄生虫的裂殖子阶段被选择性地可逆地诱导在宿主细胞或培养基中的迁移之间，从而可能大量分离感染性抗原性裂殖子。从体外培养基中大量收获特异性巴贝虫抗原。

46. 发明授权

US4281086A Polymer bound multidentate complexes 失效
标题翻译：聚合物结合的多齿络合物
公开(公告)号：US4281086A
公开(公告)日：1981-07-28
申请号：US148065
申请日：1980-05-12
申请人： John H. Gaul, Jr. , Russell S. Drago
发明人： John H. Gaul, Jr. , Russell S. Drago
IPC分类号： C08F8/28 , C08F8/32 , C08F8/42 , C08F8/18 , C08F8/26 , C08F8/30
CPC分类号： C08F8/28 , C08F12/18 , C08F212/08 , C08F2810/20
摘要： Polymer bound multidentate complexes are prepared by reacting pendant benzyl chloride and benzyl iodide groups on a variety of polymer supports, including crosslinked polystyrene, with 3,3'-iminodiproprionitrile and reducing the nitrile groups by treatment with, for example, a boron hydride-tetrahydrofuran complex to form the amine. The amine is a precursor for other ligand systems; for example, the primary amine groups formed condense with an aldehyde or ketone to yield five coordinate Schiff base ligands. The polydentate amine ligand systems are useful for synthesis of chelating agents for sequestering metal ions from solution for purification or concentration purposes. Metal complexes of these ligands with manganese, iron, cobalt, nickel, copper, and zinc can be prepared which are useful as heterogeneous oxidation catalysts.
摘要翻译：通过使各种聚合物载体（包括交联聚苯乙烯）与3,3'-亚氨基二丙腈反应，将苄基氯和苄基碘基团反应，通过用例如硼氢化物 - 四氢呋喃处理来还原腈基来制备聚合物结合的多齿络合物复合以形成胺。胺是其他配体体系的前体; 例如，伯胺基团与醛或酮缩合以产生五配位席夫碱配体。多齿胺配体体系可用于合成螯合剂，用于从溶液中螯合金属离子用于纯化或浓缩。可以制备这些配体与锰，铁，钴，镍，铜和锌的金属络合物，其可用作非均相氧化催化剂。

47. 发明授权

US4200849A Tuned unidirectional surface wave transducer 失效
标题翻译：调谐单向表面波传感器
公开(公告)号：US4200849A
公开(公告)日：1980-04-29
申请号：US920798
申请日：1978-06-30
申请人： Donald C. Malocha
发明人： Donald C. Malocha
IPC分类号： H03H3/08 , H03H9/145 , H03H9/04 , H01L41/10 , H03H9/20 , H03H9/26
CPC分类号： H03H9/14505
摘要： A surface acoustic wave device having a unidirectional input transducer is provided with an input tuning circuit which eliminates the reactive portions of the device's input impedance. The input transducer has a pair of input ports, each of which exhibits an impedance A.angle..phi.. A series tuning circuit including reactances having a magnitude of A(sin.phi.+cos.phi.) and A(sin.phi.-cos.phi.) respectively, is connected to the input ports. An alternative parallel reactive tuning circuit is disclosed whose reactances are A/(sin.phi.+cos.phi.) and A/(sin.phi.-cos.phi.) respectively.
摘要翻译：具有单向输入换能器的表面声波装置设置有输入调谐电路，其消除了装置的输入阻抗的无功部分。输入传感器具有一对输入端口，每个输入端口具有阻抗A ANGLE phi。包括分别具有A（sin phi + cos phi）和A（sin phi -cos phi）大小的电抗的串联调谐电路连接到输入端口。公开了另一种并联电抗调谐电路，其电抗分别为A /（sin phi + cos phi）和A /（sin phi -cos phi）。

48. 发明授权

US4133874A Lipid encapsulated hemoglobin cells 失效
标题翻译：脂质包封血红蛋白细胞
公开(公告)号：US4133874A
公开(公告)日：1979-01-09
申请号：US876717
申请日：1978-02-10
申请人： Irving F. Miller , Ljubomir Djordjevich
发明人： Irving F. Miller , Ljubomir Djordjevich
IPC分类号： A61K38/16 , A61K9/00 , A61K9/127 , A61K38/42 , A61K9/42 , A61K9/50 , A61K35/14 , A61K35/18
CPC分类号： A61K9/127 , A61K38/42 , Y10T428/2984
摘要： Synthetic erythrocytes. Hemoglobin is encapsulated in lipid materials to form cells which are typically 0.1 to 10 microns in their greatest dimension. Preferably cholesterol and one or more phospholipids are included in the cell membrane. The lipid membrane is of such character and thinness that O.sub.2 --CO.sub.2 transfer thereacross is readily accomplished. The preferred encapsulation process utilizes ultrasonic energy.
摘要翻译：合成红细胞。血红蛋白被包封在脂质材料中以形成其最大尺寸通常为0.1至10微米的细胞。优选胆固醇和一种或多种磷脂被包括在细胞膜中。脂质膜具有这样的性质和薄度，容易实现O 2 -CO 2转移。优选的封装工艺利用超声波能量。

49. 植物专利

USPP4217P Chrysanthemum plant 失效
公开(公告)号：USPP4217P
公开(公告)日：1978-02-21
申请号：US773978
申请日：1977-03-03
申请人： John Robert Culbert
发明人： John Robert Culbert
摘要： A novel chrysanthemum characterized by long lasting blossoms having spooned, white ray florets enclosing a yellow anemone center.

50. 发明授权

US4070243A Method for distinguishing subpopulations in a population of morphologically indistinguishable cells 失效
标题翻译：区分形态学上不可分辨细胞群体亚群的方法
公开(公告)号：US4070243A
公开(公告)日：1978-01-24
申请号：US718807
申请日：1976-08-30
申请人： Marius C. Teodorescu , Eugene P. Mayer , Sheldon Dray
发明人： Marius C. Teodorescu , Eugene P. Mayer , Sheldon Dray
IPC分类号： G01N33/50 , C12K1/02 , C12K9/00
CPC分类号： G01N33/5094
摘要： A method for identification of cell subpopulations in a population of cells which are morphologically alike, based on the ability of selected strains of bacteria to bind to the cell surface when they are brought in close contact.Selected strains of naturally occurring or artificially obtained bacteria of different species or genuses, having an affinity to bind to different subpopulations of a cell mixture, are brought into contact by centrifugation or the like with a mixture of cells such as leukocytes, the mixture is resuspended and the cells having bacteria attached are identified under the microscope. The method is useful particularly for the identification of B cells, several subpopulations of T cells, and the differentiation among leukemic cell populations.
摘要翻译：基于当所选菌株与细胞表面紧密接触时结合的能力，鉴定细胞群体中形态学相似的细胞亚群的方法。

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