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41. 发明申请

US20110065991A1 HANDGRIP FOR ASSESSMENT OF COLONOSCOPE MANIPULATION 有权
标题翻译：用于评估结肠镜手术的手术
公开(公告)号：US20110065991A1
公开(公告)日：2011-03-17
申请号：US12558737
申请日：2009-09-14
申请人： Armen P. Sarvazyan , Sergey Tsyuryupa , Vladimir Egorov , Louis Y. Korman
发明人： Armen P. Sarvazyan , Sergey Tsyuryupa , Vladimir Egorov , Louis Y. Korman
IPC分类号： A61B1/31
CPC分类号： A61B1/31 , A61B1/0052 , G06F19/00
摘要： A handgrip for colonoscope shaft is equipped with force, torque, and acceleration sensors allowing for a comprehensive characterization of colonoscope shaft motion, including recognition of obstacles and recording of forces and torques applied at various times during a colonoscopy procedure. An electronic unit is adapted to receive sensors data wirelessly and calculate a variety of motion parameters guiding a medical practitioner during the procedure and aimed at making colonoscopy safer and less painful.
摘要翻译：结肠镜手柄的手柄配备有力，扭矩和加速度传感器，可以全面表征结肠镜轴运动，包括识别障碍物以及在结肠镜检查过程中在不同时间施加的力和扭矩记录。电子单元适于无线地接收传感器数据，并计算在手术过程中指导医师的各种运动参数，并且旨在使结肠镜检查更安全且不那么痛苦。

42. 发明申请

US20110054357A1 METHODS FOR CHARACTERIZING VAGINAL TISSUE ELASTICITY 有权
标题翻译：表征VAG组织弹性的方法
公开(公告)号：US20110054357A1
公开(公告)日：2011-03-03
申请号：US12874583
申请日：2010-09-02
申请人： Vladimir Egorov , Armen P. Sarvazyan
发明人： Vladimir Egorov , Armen P. Sarvazyan
IPC分类号： A61B5/103
CPC分类号： A61B5/4337 , A61B5/0053 , A61B5/065 , A61B5/6847 , A61B5/6885 , A61B2562/0247 , A61B2562/0261 , A61B2562/046
摘要： Methods for characterizing elasticity of vaginal tissue are provided. A transvaginal probe is used to deform vaginal tissue during examination. The probe is equipped with pressure sensors and a motion tracking sensor. Stress and strain data is recorded during examination. Elasticity of vaginal tissue is then characterized by calculating a stress gradient defined as a ratio of stress over strain for each point of measurement. Vaginal tactile image may also be compiled to include a family of surfaces representing locations of measurement points at predefined constant levels of stress. Pelvic organ abnormality condition may be detected if the stress gradient is below either a predetermined threshold or a normal stress gradient obtained from clinical data.
摘要翻译：提供了表征阴道组织弹性的方法。经阴道探针用于在检查期间使阴道组织变形。探头配有压力传感器和运动跟踪传感器。在检查期间记录应力和应变数据。然后通过计算应力梯度来定义阴道组织的弹性，该应力梯度定义为每个测量点的应力与应变之比。阴道触觉图像也可以被编译成包括表示测量点的位置的表面系列，其具有预定的不变应力水平。如果应力梯度低于从临床数据获得的预定阈值或正常应力梯度，则可以检测到骨盆器官异常状况。

43. 发明申请

US20090052272A1 ULTRASONIC STIRRING OF LIQUIDS IN SMALL VOLUMES 审中-公开
标题翻译：超声波在小容量液体中的搅拌
公开(公告)号：US20090052272A1
公开(公告)日：2009-02-26
申请号：US11841456
申请日：2007-08-20
申请人： Armen P. Sarvazyan
发明人： Armen P. Sarvazyan
IPC分类号： B01F11/02
CPC分类号： B01F13/0059 , B01F11/0266 , B01F11/0283
摘要： Ultrasound-assisted contactless stirring of liquids in a resonator cell by microparticles is achieved by repeated creating and destruction of nodal patterns associated with standing waves of various resonance frequencies causing continuous movements of microparticles inside the cell. Swept-frequency sonication methods include using constant or variable rate of frequency change as well as a stepwise change of frequency of the transducer within a predefined range. Other useful steps include initial detection of the set of resonance frequencies and periodic refreshing of that set. Control systems are described including means to automatically detect the resonance frequencies and maintain the operation of the transducer thereon. Advantageous designs of the apparatus are described for use in microstirring, mixing of liquids using magnetic microbeads, microbubbles, microtiter plates, microarray plates, etc.
摘要翻译：通过重复产生和破坏与各种谐振频率的驻波相关联的节点图案，导致微粒在细胞内的连续移动，实现了通过微粒在谐振器单元中超声辅助的非接触式液体搅拌。扫频超声处理方法包括使用常数或可变速率的频率变化以及在预定范围内逐次改变换能器的频率。其他有用的步骤包括初始检测该组谐振频率和周期性刷新该组。描述了控制系统，其包括自动检测谐振频率并保持换能器在其上的操作的装置。该设备的有利设计被描述为用于微型搅拌，使用磁性微珠混合液体，微泡，微量滴定板，微阵列板等。

44. 发明授权

US06981945B1 Colonoscope handgrip with force and torque monitor 失效
标题翻译：结肠镜手柄与力和扭矩监视器
公开(公告)号：US06981945B1
公开(公告)日：2006-01-03
申请号：US10986662
申请日：2004-11-12
申请人： Armen Sarvazyan , Louis Y. Korman , Sergey Tsyuryupa
发明人： Armen Sarvazyan , Louis Y. Korman , Sergey Tsyuryupa
IPC分类号： A61B1/00
CPC分类号： A61B1/31 , A61B1/00147 , A61B1/0052
摘要： A handgrip for a colonoscope shaft capable of measuring and presenting to the operator of radial and longitudinal forces applied by the operator during the manipulation with the colonoscope. The handgrip includes an internal sleeve positioned over the shaft of the colonoscope so that it can be released and repositioned by depressing a release button. And external sleeve covers the internal sleeve and provides for a convenient grip by the operator. The only means of transmission of force applied by the operator from the external sleeve to the internal sleeve is the engaging means such as a flexible rectangular bar or a set of engaging plates imbedded between the external sleeve and internal sleeve. The engaging means are equipped with a set of sensors such as strain gages positioned on all sides of the bar to measure the forces between the sleeves, which correspond to the forces applied by the operator to the shaft of the colonoscope. The measurements are then transmitted to an electronic unit for data processing and then further to a display system such as a personal computer.
摘要翻译：一种用于殖民镜轴的手柄，其能够在与结肠镜操作期间测量并向操作者呈现由操作者施加的径向和纵向力。手柄包括位于结肠镜的轴上方的内部套筒，以便通过按下释放按钮来释放和重新定位。并且外部套筒覆盖内部套筒，并提供操作者方便的抓地力。操作者从外部套筒施加到内部套筒上的力的唯一传递手段是接合装置，例如嵌入在外部套筒和内部套筒之间的柔性矩形杆或一组接合板。接合装置配备有一组传感器，例如位于杆的所有侧面上的应变计，以测量套筒之间的力，其对应于操作者施加到结肠镜的轴上的力。然后将测量值发送到电子单元进行数据处理，然后进一步传送到诸如个人计算机的显示系统。

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