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31. 发明申请

US20050142155A1 Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods 审中-公开
标题翻译：细胞保护化合物，药物和化妆品制剂及方法
公开(公告)号：US20050142155A1
公开(公告)日：2005-06-30
申请号：US11055895
申请日：2005-02-10
申请人： Bing Wang , Yong-Kang Zhang , Jian Chen , Wei Zhang , Jiangao Song , Ughetta Del Balzo , Lesley Brown , Sekhar Boddupalli , Steven Bobzin , Sylvain Gilat , Guy Miller
发明人： Bing Wang , Yong-Kang Zhang , Jian Chen , Wei Zhang , Jiangao Song , Ughetta Del Balzo , Lesley Brown , Sekhar Boddupalli , Steven Bobzin , Sylvain Gilat , Guy Miller
IPC分类号： C07D295/18 , A61K8/00 , A61K8/30 , A61K31/05 , A61K31/055 , A61K31/06 , A61K31/085 , A61K31/09 , A61K31/10 , A61K31/122 , A61K31/15 , A61K31/166 , A61K31/18 , A61K31/192 , A61K31/21 , A61K31/235 , A61K31/277 , A61K31/28 , A61K31/30 , A61K31/315 , A61K31/343 , A61K31/353 , A61K31/36 , A61K31/381 , A61K31/4164 , A61K31/4184 , A61K31/426 , A61K31/4425 , A61K31/444 , A61K31/4453 , A61K31/5375 , A61K31/555 , A61K31/662 , A61K31/7024 , A61K33/32 , A61P1/04 , A61P3/10 , A61P5/24 , A61P9/00 , A61P9/04 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/10 , A61P17/16 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/28 , A61P27/02 , A61P29/00 , A61P37/06 , A61P43/00 , A61Q19/00 , A61Q19/02 , C07C39/21 , C07C39/373 , C07C39/44 , C07C43/215 , C07C43/23 , C07C45/30 , C07C45/71 , C07C49/737 , C07C49/747 , C07C50/34 , C07C69/007 , C07C69/76 , C07C69/94 , C07C205/17 , C07C205/20 , C07C205/22 , C07C205/35 , C07C205/57 , C07C235/42 , C07C255/15 , C07C255/36 , C07C255/53 , C07C255/54 , C07C311/29 , C07C317/22 , C07D213/30 , C07D213/53 , C07D231/22 , C07D231/26 , C07D233/24 , C07D233/64 , C07D235/08 , C07D277/20 , C07D277/24 , C07D277/30 , C07D277/34 , C07D295/22 , C07D295/26 , C07D307/83 , C07D311/72 , C07D317/62 , C07D333/16 , C07F1/08 , C07F9/40 , C07H13/08 , A61K7/42 , A61K31/4152 , A61K31/42 , C07D231/08 , C07D261/12
CPC分类号： C07D213/30 , C07C43/23 , C07C45/30 , C07C45/71 , C07C49/737 , C07C69/94 , C07C205/17 , C07C205/20 , C07C205/22 , C07C205/35 , C07C205/57 , C07C235/42 , C07C255/36 , C07C311/29 , C07C2603/24 , C07D213/53 , C07D231/26 , C07D277/20 , C07D277/24 , C07D295/26 , C07D311/72 , C07F9/4021 , C07C47/575
摘要： Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
摘要翻译：细胞保护性化合物，其中许多是以具有某些缀合键的取代苯酚为特征的酚类衍生物，可用于治疗某些缺血性或炎症性疾病，包括但不限于中风，心肌梗死，充血性心力衰竭和特征为炎症或氧化损伤。它们也可用于制造用于治疗这些病症的药物和化妆品制剂。

32. 发明申请

US20050142080A1 Cosmetic or dermatological light protection formulation with a benzoxazole derivative 审中-公开
标题翻译：化妆品或皮肤科防晒配方用苯并恶唑衍生物
公开(公告)号：US20050142080A1
公开(公告)日：2005-06-30
申请号：US10871819
申请日：2004-06-18
申请人： Anja Goppel , Jens Schulz , Heike Lerg
发明人： Anja Goppel , Jens Schulz , Heike Lerg
IPC分类号： A61K8/49 , A61Q17/04 , A61K7/42
CPC分类号： A61K8/49 , A61Q17/04
摘要： The invention is a light protection-active cosmetic or dermatological preparation comprising (a) at least one benzoxazole derivative, and (b) at least one oil component having a surface tension (σ) of less than 37 mN/m (at 25° C). The invention is also a method of treating or preventing cosmetic or dermatological changes in the skin, a method of tanning or accelerating tanning of the skin, and a method of protecting the skin against light-induced aging, each comprising applying the cosmetic or dermatological preparation to the skin. The invention is also a method of increasing the solubility of benzoxazole in a preparation comprising adding at least one oil component. The invention also includes a wipe impregnated with the preparation.
摘要翻译：本发明是一种防光活性化妆品或皮肤病学制剂，其包含（a）至少一种苯并恶唑衍生物，和（b）至少一种表面张力（σ）小于37mN / m（在25℃））。本发明还是一种治疗或预防皮肤的化妆品或皮肤病学改变的方法，鞣制或加速皮肤鞣制的方法，以及保护皮肤免受光诱导的老化的方法，每种方法包括施用化妆品或皮肤病学制剂到皮肤。本发明也是增加苯并恶唑在包含添加至少一种油组分的制剂中的溶解度的方法。本发明还包括浸渍有制剂的擦拭物。

33. 发明申请

US20050129631A1 Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates 有权
标题翻译：化妆品和皮肤科防晒配方，含羟基二苯甲酮和烷基萘磺酸盐
公开(公告)号：US20050129631A1
公开(公告)日：2005-06-16
申请号：US10500869
申请日：2002-11-02
申请人： Anja Goppel , Jens Schulz , Volker Wendel
发明人： Anja Goppel , Jens Schulz , Volker Wendel
IPC分类号： A61K8/35 , A61K8/37 , A61Q17/04 , A61K7/42
CPC分类号： A61K8/35 , A61K8/37 , A61Q17/04
摘要： The invention relates to light-protective cosmetic or dermatological preparations that contain (a) at least one hydroxy-benzophenone, and (b) at last one dialkyl naphthalate of the structural formula (1), wherein R1 and R2 are independently selected form the group of the branched and unbranched alkyl groups that have 6 to 24 carbon atoms. The invention further relates to the use of said formulations.
摘要翻译：本发明涉及含有（a）至少一种羟基 - 二苯甲酮的光保护性化妆品或皮肤病学制剂，和（b）最后一种结构式（1）的萘二甲酸二烷基酯，其中R 1，和R 2独立地选自具有6至24个碳原子的支链和非支链烷基的基团。本发明还涉及所述制剂的用途。

34. 发明授权

US06905690B2 Citrullinylarginine dipeptide analogs and their dermatological uses as care and treatment agents 有权
标题翻译：柠檬酰精氨酸二肽类似物及其皮肤病学用途作为护理和治疗剂
公开(公告)号：US06905690B2
公开(公告)日：2005-06-14
申请号：US10404058
申请日：2003-04-02
申请人： Marie-Christine Seguin
发明人： Marie-Christine Seguin
IPC分类号： A61K8/44 , A61K8/64 , A61K8/97 , A61K36/02 , A61K36/04 , A61K38/05 , A61K38/16 , A61P17/00 , A61Q19/00 , A61Q19/06 , A61Q19/08 , A61K35/80 , A61K7/42
CPC分类号： A61Q19/08 , A61K8/44 , A61K8/64 , A61K8/9706 , A61K36/02 , A61K36/04 , A61K38/05 , A61Q19/00 , A61Q19/06
摘要： The present invention relates to an algal adduct of the citrullinylarginine natural dipeptide as well as to its dermatological use and the use of chemical analogs issued from the same dipeptide displaying no toxic potential, as skin and phanera care and treatment agents, the said analogs having the following general formula (I): in which: R1 represents an acyl or acycloxy radical, R2 represents a hydroxyl, amine, alkylamine or alcoxy radical, R3 represents a hydrogen atom or a hydroxyl radical.
摘要翻译：本发明涉及瓜氨酸精氨酸天然二肽的藻类加合物以及其皮肤病学用途以及使用由不具有毒性潜力的相同二肽发出的化学类似物作为皮肤和香精护理和治疗剂，所述类似物具有通式（I）：其中：R 1表示酰基或酰基，R 2表示羟基，胺，烷基胺或烷氧基，R 1， 3 表示氢原子或羟基。

35. 发明授权

US06902722B2 Aqueous antisun/sunscreen compositions comprising amphiphilic 2-acrylamidomethylpropanesulfonic acid polymers and water-soluble silicones 失效
标题翻译：包含两亲性2-丙烯酰胺基甲基丙磺酸聚合物和水溶性有机硅的水性防晒/防晒组合物
公开(公告)号：US06902722B2
公开(公告)日：2005-06-07
申请号：US10823669
申请日：2004-04-14
申请人： Didier Candau , Karl Boutelet , Nathalie Seyler
发明人： Didier Candau , Karl Boutelet , Nathalie Seyler
IPC分类号： A61K8/58 , A61K8/81 , A61K8/891 , A61K8/894 , A61Q17/04 , A61K7/42 , A61K7/00 , A61K7/44
CPC分类号： A61K8/894 , A61K8/585 , A61K8/8152 , A61K8/8158 , A61Q17/04 , B82Y5/00
摘要： Photoprotective compositions well suited for the photoprotection of the skin, lips and/or hair against the damaging effect of UV-radiation comprise at least one aqueous phase and at least one system for screening out UV-radiation, and which also contain: (a) at least one partially or totally neutralized, crosslinked or non-crosslinked amphiphilic polymer of 2-acrylamidomethylpropanesulfonic acid (AMPS), and (b) at least one water-soluble silicone comprising at least one terminal or pendent monovalent polyoxyalkylene group.
摘要翻译：抗紫外线辐射的破坏性影响的皮肤，嘴唇和/或头发的光保护的光保护组合物包含至少一个水相和至少一个用于筛选紫外线辐射的系统，并且还包含：（a）至少一种部分或完全中和的交联或非交联的2-丙烯酰胺基甲基丙磺酸（AMPS）的两亲性聚合物，和（b）至少一种包含至少一个末端或侧挂单价聚氧化烯基团的水溶性硅氧烷。

36. 发明申请

US20050118118A1 Lipid A-type compound and composition containing it 有权
标题翻译：脂质A型化合物和含有它的组合物
公开(公告)号：US20050118118A1
公开(公告)日：2005-06-02
申请号：US10972411
申请日：2004-10-26
申请人： Richard Martin
发明人： Richard Martin
IPC分类号： A61K8/60 , A61K8/99 , A61K31/166 , A61Q17/04 , A61Q19/08 , C07H3/04 , C07H11/04 , C08B37/00 , A61K7/42
CPC分类号： C07H3/04 , A61K8/602 , A61K8/99 , A61K31/166 , A61K2039/55594 , A61Q17/04 , A61Q19/08 , C07H11/04 , A61K2300/00
摘要： Compounds of the formula: and compositions containing one or more such compounds, the compositions preferably being suitable for topical application to the skin.
摘要翻译：下式的化合物和含有一种或多种这样的化合物的组合物，该组合物优选适于局部施用于皮肤。

37. 发明授权

US06899866B2 Photostabilization of a sunscreen composition with a combination of an α-cyano-β, β-diphenylacrylate compound and a dialkyl naphithalate 失效
标题翻译：使用α-氰基-β，β-二苯基丙烯酸酯化合物和二烷基萘甲酸酯的组合的防晒组合物的光稳定化
公开(公告)号：US06899866B2
公开(公告)日：2005-05-31
申请号：US10785271
申请日：2004-02-24
申请人： Craig A. Bonda
发明人： Craig A. Bonda
IPC分类号： A61K8/35 , A61K8/37 , A61K8/39 , A61K8/40 , A61K8/85 , A61K8/86 , A61Q17/04 , A61K7/00 , A61K7/42 , A61K7/44
CPC分类号： A61K8/37 , A61K8/35 , A61K8/40 , A61K8/85 , A61K8/86 , A61K2800/52 , A61Q17/04
摘要： Sunscreen compositions including a dibenzoylmethane derivative, such as avobenzone, that are made more stable by the addition of (a) an α-cyano-β,β-diphenylacrylate compound, e.g., octocrylene and (b) a diester or polyester of naphthalene dicarboxylic acid (diethylhexyl 2,6-naphthalate), having a weight ratio of (a)/(b) of at least 0.95, preferably at least about 1.0. More particularly, the invention relates to sunscreen compositions which utilize a combination of octocrylene and diethylhexyl 2,6-naphthalate to stabilize other photoactive compounds present in a sunscreen composition and, in particular, to stabilize dibenzoylmethane derivatives, without, or with levels less than 0.5% by weight of, a methoxy-substituted benzophenone derivative, such as benzophenone-3.
摘要翻译：通过添加（a）α-氰基-β-二苯基丙烯酸酯化合物（例如，八亚甲基）和（b）萘二羧酸的二酯或聚酯来制备包含二苯甲酰甲烷衍生物如阿伏苯宗的防晒组合物，（a）/（b）的重量比为至少0.95，优选至少约1.0的（2,6-萘二甲酸二乙基己酯）。更具体地说，本发明涉及防晒组合物，其使用辛基苯二酚和2,6-萘二甲酸二乙基己酯的组合来稳定存在于防晒组合物中的其它光活性化合物，特别是稳定二苯甲酰甲烷衍生物，不含或低于0.5 重量％的甲氧基取代的二苯甲酮衍生物，例如二苯甲酮-3。

38. 发明授权

US06890522B2 Cosmetic and personal care compositions 失效
标题翻译：化妆品和个人护理组合物
公开(公告)号：US06890522B2
公开(公告)日：2005-05-10
申请号：US10698067
申请日：2003-10-30
申请人： Jean M. J. Frechet , Damian Hajduk , Ezat Khoshdel , Mingjun Liu , Ralph B. Nielsen , Euan Stuart Reid , Keith Leslie Rutherford
发明人： Jean M. J. Frechet , Damian Hajduk , Ezat Khoshdel , Mingjun Liu , Ralph B. Nielsen , Euan Stuart Reid , Keith Leslie Rutherford
IPC分类号： A61K8/00 , A61K8/90 , A61Q5/00 , A61Q5/06 , A61K7/06 , A61K7/075 , A61K7/08 , A61K7/42 , A61K47/32
CPC分类号： A61Q5/06 , A61K8/90 , A61K2800/54
摘要： Cosmetic or personal care compositions, such as for styling hair, comprise a thermoplastic elastomer which is a block copolymer comprising a core polymer having a backbone comprising at least a proportion of C—C bonds and two or more flanking polymers. Each flanking polymer is covalently bound to an end of the core polymer and the core polymer and/or at least one of the flanking polymers is a copolymer derived from two or more monomers. The compositions comprise a cosmetically acceptable diluent or carrier.
摘要翻译：化妆品或个人护理组合物，例如用于造型头发，包含热塑性弹性体，其是包含具有包含至少一部分C-C键和两个或更多个侧翼聚合物的主链的芯聚合物的嵌段共聚物。每个侧翼聚合物共价结合到芯聚合物的末端，并且核心聚合物和/或至少一个侧翼聚合物是衍生自两种或更多种单体的共聚物。组合物包含美容上可接受的稀释剂或载体。

39. 发明授权

US06881415B1 Emulsifier-free finely dispersed water-in-oil type systems 失效
标题翻译：无乳化剂的细分散的油包水型系统
公开(公告)号：US06881415B1
公开(公告)日：2005-04-19
申请号：US10031554
申请日：2000-07-18
申请人： Heinrich Gers-Barlag , Anja Moller , Michaela Kohut
发明人： Heinrich Gers-Barlag , Anja Moller , Michaela Kohut
IPC分类号： A61K9/10 , A61K8/06 , A61K8/19 , A61K8/25 , A61K8/27 , A61K8/29 , A61K8/30 , A61K8/46 , A61K8/49 , A61K8/72 , A61K8/73 , A61K8/92 , A61K9/107 , A61K45/00 , A61K47/02 , A61K47/20 , A61K47/22 , A61P17/00 , A61Q17/04 , B01F17/54 , A61K7/00 , A61K7/42 , A61K7/44 , A61K31/53
CPC分类号： A61K8/064 , A61K8/06 , A61K8/25 , A61K8/27 , A61K8/29 , A61K8/466 , A61K8/4946 , A61K8/4966 , A61K8/498 , A61K2800/33 , A61Q17/04 , B01F17/0071 , Y10S514/938
摘要： Cosmetic or dermatological preparations which are finely disperse systems of the water-in-oil type, comprising 1. an oil phase, 2. a water phase, 3. at least one modified phyllosilicate which exhibits both hydrophilic and lipophilic properties, i.e. which has amphiphilic character and positions itself at the water/oil interface and 4. at most 0.5% by weight of one or more emulsifiers and optionally comprising further cosmetic or pharmaceutical auxiliaries, additives and/or active ingredients.
摘要翻译：油包水型的细分散系统的化妆品或皮肤病学制剂，包括1.油相，2.水相，3.至少一种表现出亲水性和亲脂性的两种修饰的页硅酸盐，即具有两亲性特征和位置在水/油界面和4.至多0.5重量％的一种或多种乳化剂，并且任选地包含其它化妆品或药物助剂，添加剂和/或活性成分。

40. 发明授权

US06878378B1 External skin care composition 有权
标题翻译：外用护肤品
公开(公告)号：US06878378B1
公开(公告)日：2005-04-12
申请号：US09564549
申请日：2000-05-04
申请人： Kazuhiro Yamaki , Tomohiko Sano , Kimihiko Hori , Yutaka Takagi , Yukihiro Ohashi
发明人： Kazuhiro Yamaki , Tomohiko Sano , Kimihiko Hori , Yutaka Takagi , Yukihiro Ohashi
IPC分类号： A61K8/00 , A61K8/58 , A61K8/67 , A61K8/68 , A61K8/73 , A61K8/81 , A61K8/86 , A61K8/891 , A61K8/894 , A61K8/898 , A61K8/96 , A61K8/97 , A61K36/61 , A61Q1/02 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q1/12 , A61Q3/02 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/10 , A61K7/00 , A61K7/021 , A61K7/04 , A61K7/42 , A61K9/14
CPC分类号： A61K8/894 , A61K8/585 , A61K8/675 , A61K8/73 , A61K8/8152 , A61K8/8176 , A61K8/86 , A61K8/891 , A61K8/97 , A61Q1/02 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q1/12 , A61Q3/02 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/10
摘要： The invention relates to an external skin care composition comprising a ceramide production-accelerating agent and a film-forming polymer. The external skin care composition can enhance the barrier function of the skin and has an excellent skin roughness-improving effect.
摘要翻译：本发明涉及包含神经酰胺生产促进剂和成膜聚合物的外用皮肤护理组合物。外用护肤组合物可以增强皮肤的屏障功能，并且具有优异的皮肤粗糙度改善效果。

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