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31. 发明授权

US08877026B2 Electrode assembly 有权
标题翻译：电极组件
公开(公告)号：US08877026B2
公开(公告)日：2014-11-04
申请号：US13435897
申请日：2012-03-30
申请人： Hisashi Yamanouchi , Hiromi Ohkawa , Koji Ueda
发明人： Hisashi Yamanouchi , Hiromi Ohkawa , Koji Ueda
IPC分类号： G01N27/333 , G01N27/403 , G01N27/28 , G01N27/414
CPC分类号： G01N27/283 , G01N27/414
摘要： The electrode assembly is provided with: a rod-like body 1 that extends along a predetermined axis; a substrate that is formed with a through-hole penetrating between a front surface and a back surface and attached to a fore end part of the body; and a sensor chip for electrochemical measurement, which is attached on the back surface of the substrate such that a sensing part is exposed outside from the through-hole, wherein: on the back surface of the substrate, a wiring for obtaining an output signal from the ISFET chip is formed, and the sensor chip is attached to the wiring directly or closely; and the substrate is attached with being inclined with respect to the predetermined axis of the body, and thereby the front surface of the substrate forms at least a part of a fore end surface that is inclined with respect to the predetermined axis.
摘要翻译：电极组件设置有：沿预定轴线延伸的杆状体1; 形成有穿透前表面和后表面之间的通孔的基底，并附着到身体的前端部; 以及用于电化学测量的传感器芯片，其安装在所述基板的背面上，使得感测部分从所述通孔暴露在外部，其中：在所述基板的背面上，用于获得来自形成ISFET芯片，并且将传感器芯片直接或紧密地附接到布线; 并且基板相对于本体的预定轴线倾斜地附接，从而基板的前表面形成相对于预定轴线倾斜的前端表面的至少一部分。

32. 发明授权

US08673624B2 Calibratable sensor unit for reaction vessels 有权
标题翻译：用于反应容器的可校准传感器单元
公开(公告)号：US08673624B2
公开(公告)日：2014-03-18
申请号：US13024662
申请日：2011-02-10
申请人： Andreas Loebbert , Dirk Schoenfuss
发明人： Andreas Loebbert , Dirk Schoenfuss
IPC分类号： C12M1/34 , C12M3/00 , G01D18/00
CPC分类号： G01N33/00 , C12M23/26 , C12M23/28 , C12M41/26 , C12M41/32 , C12M41/34 , C12M41/36 , C12M41/40 , G01N27/283 , G01N27/4165 , G01N33/84
摘要： The present invention relates to a calibratable sensor unit for a reaction vessel, such as for example a fermenter (48), in particular a disposable fermenter, comprising at least one sensor device (14) to be calibrated and at least one compartment (26, 28, 30) containing a calibrating agent, the at least one sensor device and the at least one compartment (26, 28, 30) being accommodated movably relative to one another in a housing (12) that is connected to or can be connected to the reaction vessel (48), wherein the calibrating unit (10) is arranged to calibrate the at least one sensor device (14) by contact with the calibrating agent before chemical and/or physical parameters of a measurement substance are measured with the at least one sensor device (14). According to the invention it is proposed that the sensor device (10) is configured in such a way that the relative movement between the at least one sensor device (14) and the at least one compartment (26, 28, 30) can be carried out irreversibly.
摘要翻译：本发明涉及用于反应容器的可校准传感器单元，例如发酵罐（48），特别是一次性发酵罐，包括至少一个要校准的传感器装置（14）和至少一个隔室（26，包含校准剂的至少一个传感器装置和所述至少一个传感器装置和所述至少一个隔室（26,28,30）在壳体（12）中相对于彼此可移动地容纳，所述壳体连接到或可以连接到所述反应容器（48），其中所述校准单元（10）被布置成通过与所述校准剂接触来校准所述至少一个传感器装置（14），在测量所述测量物质的化学和/或物理参数被测量至少一个传感器装置（14）。根据本发明，提出传感器装置（10）被构造成使得至少一个传感器装置（14）和至少一个隔室（26,28,30）之间的相对运动可以被运送不可逆转

33. 发明授权

US08444835B2 Electronic and fluidic interface 有权
标题翻译：电子和流体界面
公开(公告)号：US08444835B2
公开(公告)日：2013-05-21
申请号：US12878135
申请日：2010-09-09
申请人： Oguz H. Elibol , Jonathan S. Daniels , Stephane L. Smith
发明人： Oguz H. Elibol , Jonathan S. Daniels , Stephane L. Smith
IPC分类号： G01N27/403
CPC分类号： B01L3/502715 , B01L2200/0689 , B01L2300/0645 , B01L2300/0877 , B01L2300/14 , B01L2400/0487 , G01N27/283
摘要： An electronic fluidic interface for use with an electronic sensing chip is provided. The electronic fluidic interface provides fluidic reagents to the surface of a sensor chip. The electronic sensing chip typically houses an array of electronic sensors capable of collecting data in a parallel manner. The electronic fluidic interface is used, for example, as part of a system that drives the chip and collects, stores, analyzes, and displays data from the chip and as part of a system for testing chips after manufacture. The electronic fluidic interface is useful, for example, nucleic sequencing applications.
摘要翻译：提供了一种与电子感测芯片一起使用的电子流体接口。电子流体界面向传感器芯片的表面提供流体试剂。电子感测芯片通常容纳能够以并行方式收集数据的电子传感器阵列。电子流体接口例如用作驱动芯片并且从芯片收集，存储，分析和显示数据的系统的一部分，并且作为用于在制造之后测试芯片的系统的一部分。电子流体界面是有用的，例如核酸测序应用。

34. 发明授权

US08418551B2 Retractable assembly for a sensor 有权
标题翻译：传感器伸缩组件
公开(公告)号：US08418551B2
公开(公告)日：2013-04-16
申请号：US13140086
申请日：2009-11-27
申请人： Ingrid Wunderlich , Thomas Pfauch
发明人： Ingrid Wunderlich , Thomas Pfauch
IPC分类号： G01D11/24
CPC分类号： G01N27/283
摘要： A retractable assembly for a sensor, which determines a physical and/or chemical, process variable in a process medium. The retractable assembly has a housing, in which a tubular holder for accommodating the sensor is arranged such that it can be moved linearly by a drive unit. At least one cascaded cylinder is provided for the linear shifting of the tubular holder, wherein the cascaded cylinder comprises at least two cylinders arranged one after the other in the direction of the stroke movement. Furthermore, the cascaded cylinder is, or the cascaded cylinders are, embodied and/or operable in such a manner that the sensor is movable into at least two different positions.
摘要翻译：用于传感器的可伸缩组件，其确定处理介质中的物理和/或化学过程变量。可伸缩组件具有壳体，其中用于容纳传感器的管状保持器布置成使得其可以通过驱动单元线性移动。提供至少一个级联的气缸用于管状保持器的线性移动，其中级联气缸包括在行程运动方向上一个接一个地布置的至少两个气缸。此外，级联的气缸是或级联的气缸被实施和/或可操作，使得传感器可移动到至少两个不同的位置。

35. 发明授权

US08197653B2 Electrolyte cartridge unit for an electrochemical sensor 有权
标题翻译：用于电化学传感器的电解质墨盒单元
公开(公告)号：US08197653B2
公开(公告)日：2012-06-12
申请号：US12269492
申请日：2008-11-12
申请人： Yannick Delessert , Daniel Rosset , Gérard Stehlé , James Hide , Serge Hediger
发明人： Yannick Delessert , Daniel Rosset , Gérard Stehlé , James Hide , Serge Hediger
IPC分类号： G01N27/403
CPC分类号： G01N27/283
摘要： Cartridge unit for an electrochemical sensor includes a cartridge (2) prefilled with electrolyte and having a first end closed by a selectively permeable membrane (7), and a second end (6) having a fastening device (11) arranged for fastening the cartridge to the electrochemical sensor (24). The cartridge unit further has a supporting member (3) to which the cartridge (2) is detachably fastened, and closing devices (4, 20) for closing the second end (6) of the cartridge (2). These closing devices (4, 20) are able to be opened by a user to allow the cartridge (2) to be fastened to the electrochemical sensor (24) and then to be detached from the supporting element (3).
摘要翻译：用于电化学传感器的盒单元包括预充满电解质并具有由选择性渗透膜（7）封闭的第一端的盒（2），以及具有紧固装置（11）的第二端（6），所述紧固装置电化学传感器（24）。墨盒单元还具有可拆卸地紧固墨盒（2）的支撑构件（3），以及用于封闭墨盒（2）的第二端（6）的关闭装置（4,20）。这些关闭装置（4,20）能够由使用者打开以允许盒（2）紧固到电化学传感器（24），然后从支撑元件（3）拆下。

36. 发明申请

US20110048942A1 Adjustable, Retractable Probe Insertion Assembly 有权
标题翻译：可调节伸缩式探头插入组件
公开(公告)号：US20110048942A1
公开(公告)日：2011-03-03
申请号：US12842729
申请日：2010-07-23
申请人： Stephen B. Talutis
发明人： Stephen B. Talutis
IPC分类号： G01N27/26 , B23P19/04
CPC分类号： G01N27/26 , G01N27/283 , Y10T29/49826
摘要： An adjustable insertion assembly for an electrochemical sensor includes an electrode holder to receive the sensor, having a distal aperture to permit process fluid to contact the sensor. A receptacle slidably receives the holder, for a sliding range of motion extending from fully inserted to fully retracted positions. An open distal end portion of the receptacle extends through a wall of a process fluid vessel, so that the aperture is open to the process fluid when fully inserted, and closed when fully retracted. A leverage member is releasably movable relative to the receptacle, and moves with a captured extension. An abutment of the receptacle engages the extension so that movement of the leverage member in opposite directions alternately clamps and releases the electrode holder relative to the receptacle to substantially prevent and permit movement at substantially any point within the range of movement.
摘要翻译：用于电化学传感器的可调节插入组件包括用于接收传感器的电极夹持器，具有远端孔径以允许工艺流体接触传感器。插座可滑动地容纳保持器，用于从完全插入到完全缩回位置延伸的滑动运动范围。容器的开放的远端部分延伸穿过过程流体容器的壁，使得当完全插入时孔径对工艺流体开放，并且在完全缩回时关闭。杠杆构件相对于容器可释放地移动，并且以捕获的延伸部移动。插座的支座接合延伸部，使得杠杆元件在相反方向上的运动交替地相对于插座夹紧并释放电极支架，从而基本上防止并允许在运动范围内的任何点上移动。

37. 发明授权

US07886624B1 Portable insertable probe assembly including hazardous operations capability 有权
标题翻译：便携式可插入探头组件，包括危险操作能力
公开(公告)号：US07886624B1
公开(公告)日：2011-02-15
申请号：US11836431
申请日：2007-08-09
申请人： Donald P. Mayeaux
发明人： Donald P. Mayeaux
IPC分类号： G01M19/00
CPC分类号： G01N1/2035 , G01N17/046 , G01N27/283 , G01N35/1079 , G01N2001/105
摘要： An assembly for insertion and retraction of probe or probe-like device which does not require a seal or packing gland, instead utilizing pressure equalization between pressurized process fluids and the housing containing a probe, so as to negate the use of a dynamic seal. The preferred embodiment of the present invention contemplates an inserting/retraction mechanism for raising and lowering the probe into and from the pressurized fluid, respectively. A housing having a valve is configured to allow fluid communication between the pressurized fluid source, and the interior of the housing assembly. A conduit engages the housing assembly, and is formed to slidingly receive the outer diameter of the probe therethrough, such that a sliding seal maintains a fluid seal between the outer wall of the probe and the inner wall of the conduit, as the probe is telescoped therethrough during insertion and retraction of the probe into/from the pressurized process.
摘要翻译：用于插入和缩回探针或探针状装置的组件，其不需要密封或密封压盖，而是使用加压工艺流体和包含探针的壳体之间的压力平衡，以便否定动态密封件的使用。本发明的优选实施例考虑了用于将探针分别升高和降低到加压流体和/或从压力流体降低的插入/缩回机构。具有阀的壳体被构造成允许加压流体源和壳体组件的内部之间的流体连通。导管接合壳体组件，并且形成为滑动地容纳穿过其中的探针的外径，使得滑动密封件在探针的外壁和导管的内壁之间保持流体密封，因为探针被套叠在将探针插入加压过程中或从加压过程中回缩时，其通过其流过。

38. 发明授权

US07806009B2 Immersion tube for a measuring probe 有权
标题翻译：用于测量探头的浸入管
公开(公告)号：US07806009B2
公开(公告)日：2010-10-05
申请号：US11763780
申请日：2007-06-15
申请人： Michael Tottewitz , Daniel Caderas
发明人： Michael Tottewitz , Daniel Caderas
IPC分类号： G01D21/00
CPC分类号： G01D11/245 , G01N27/283
摘要： An immersion tube for a measuring probe of a type where a sensor element is arranged at the end of the measuring probe has a sleeve and an end piece. The end piece includes a plug, a connector piece, and a protector basket arranged between the plug and the connector piece. The connector piece connects the end piece to the sleeve and has an internal diameter that is enlarged relative to the internal diameter of the protector basket. The enlarged internal diameter portion ends at a circular internal step that can be seat for a sealing means, can provide a circular sealing lip, or both. A breakthrough opening on the protector basket is arranged perpendicular to the longitudinal axis of the immersion tube, whereby the sensor element which in operation is located in the protector basket can be brought into direct contact with a measurement medium. All surfaces and edges of the immersion tube which are exposed to the measurement medium during operation are smooth and rounded.
摘要翻译：传感器元件布置在测量头端部的测量探针用浸入管具有套筒和端部件。端件包括插头，连接器部件和布置在插头和连接器部件之间的保护器篮。连接件将端件连接到套筒上，并具有相对于保护篮的内径增大的内径。扩大的内径部分以能够用于密封装置的圆形内部台阶结束，可以提供圆形密封唇缘或两者。保护篮上的突破开口垂直于浸入管的纵向轴线布置，由此操作中位于保护篮中的传感器元件可以与测量介质直接接触。在操作过程中暴露于测量介质的浸入管的所有表面和边缘是平滑和圆形的。

39. 发明授权

US07686931B2 Safety device for an insertion electrode device 失效
标题翻译：用于插入电极装置的安全装置
公开(公告)号：US07686931B2
公开(公告)日：2010-03-30
申请号：US10814280
申请日：2004-04-01
申请人： Jelena Milanovic
发明人： Jelena Milanovic
IPC分类号： G01N27/30
CPC分类号： G01D11/245 , G01N27/283
摘要： A insertion electrode device, which is configured for installing a sensor probe in a container for a measuring medium, includes a probe housing that can be attached to the container and has a probe protector tube serving to receive, hold and guide the sensor probe. The sensor probe has a coupling for electrical connections, and the probe housing is equipped with a protective sleeve to protect the coupling from mechanical stress and moisture. The protective sleeve is connectable to the probe protector tube. A safety adapter is coupled to the end of the probe protector tube that is outside the container. The safety adapter engages a recess of the sensor probe or reaches over a step of the sensor probe and thereby secures the latter against moving in the axial direction.
摘要翻译：被配置为将传感器探针安装在用于测量介质的容器中的插入电极装置包括可附接到容器并具有用于接收，保持和引导传感器探针的探针保护管的探针外壳。传感器探头具有用于电气连接的联轴器，探头外壳配有保护套，以保护联轴器免受机械应力和潮湿。保护套可连接到探针保护管。安全适配器联接到位于容器外部的探针保护管的端部。安全适配器接合传感器探头的凹部或达到传感器探头的台阶，从而固定传感器探针，以防止其沿轴向移动。

40. 发明申请

US20090301874A1 Electrochemical Sensor 有权
标题翻译：电化学传感器
公开(公告)号：US20090301874A1
公开(公告)日：2009-12-10
申请号：US12226270
申请日：2007-03-21
申请人： Lothar Auerswald , Christian Fanselow
发明人： Lothar Auerswald , Christian Fanselow
IPC分类号： G01N27/26
CPC分类号： G01N27/283
摘要： A combination electrode, including: A first tube; a measuring membrane, which sealedly closes the first tube to form a measuring chamber; a second tube, which surrounds the first tube and is connected borderingly with the first tube to form an annular reference chamber; a buffer solution located in the measuring chamber; an electrolyte solution located in the reference chamber; a first tapping electrode in contact with the buffer solution; and a second tapping electrode in contact with the electrolyte; wherein, additionally, arranged in the reference chamber is an axially shiftable, annular, sealing element, which bounds the volume occupied by the electrolyte solution, the sealing element is biased by means of an electrically conductive, elastic, deformation element, which surrounds the first tube, and the second tapping electrode is electrically connected with the deformation element, in order to tap the potential of the second electrode via the deformation element.
摘要翻译：组合电极，包括：第一管; 测量膜，密封地封闭第一管以形成测量室; 第二管，其围绕第一管并且与第一管边界连接以形成环形参考室; 位于测量室中的缓冲溶液; 位于参考室中的电解质溶液; 与缓冲溶液接触的第一敲击电极; 和与电解质接触的第二敲击电极; 其中，另外，布置在参考室中的是轴向移动的环形密封元件，其限定由电解质溶液占据的体积，密封元件通过导电的弹性变形元件偏置，该元件围绕第一管，并且第二分接电极与变形元件电连接，以便经由变形元件分离第二电极的电位。

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