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31. 发明授权

US06796164B2 Integrated fluidics system for simplified analysis of aerosolized biological particles and particle detection ticket thereof 有权
标题翻译：集成流体系统，用于简化雾化生物颗粒的分析和颗粒检测票
公开(公告)号：US06796164B2
公开(公告)日：2004-09-28
申请号：US10288128
申请日：2002-11-04
申请人： Michael P. McLoughlin , Micah A. Carlson
发明人： Michael P. McLoughlin , Micah A. Carlson
IPC分类号： G01N100
CPC分类号： G01N1/2273 , G01N35/1004 , G01N2001/2217
摘要： An integrated fluidics system for simplified analysis of aerosolize biological particles has a unitary self-contained ticket provided with a sample fluid reservoir, an array of particle-detection strips, which is located adjacent to the sample reservoir, and, optionally, a cleaning fluid reservoir and an impinging nozzle. The fluidics system is, thus, configured to substantially minimize the fluid paths between the components of the system.
摘要翻译：用于简化气雾化生物颗粒分析的集成流体系统具有一个单独的独立票，其中提供有样品流体储存器，位于样本储存器附近的颗粒检测条的阵列，以及可选地，清洁流体储存器和冲击喷嘴。因此，流体系统构造成基本上最小化系统的部件之间的流体路径。

32. 发明申请

US20040025963A1 Air samplers 有权
标题翻译：空气取样器
公开(公告)号：US20040025963A1
公开(公告)日：2004-02-12
申请号：US10381947
申请日：2003-03-31
发明人： David James Squirrell , William Hunter Symonds , Hilary Anne Bird , Martin John Berry
IPC分类号： B65B003/26 , B65B001/30
CPC分类号： G01N1/2273 , G01N1/2211 , G01N1/24 , G01N1/26 , G01N1/34 , G01N2001/2217 , G01N2001/2223 , G01N2001/4066
摘要： With reference to FIG. 1, and air sampler 1 for use in analysing biological or other analytes, comprises an airflow chamber 2 having an air inlet 3 and an air outlet 4. An extract from 5, draws ambient air in through the inlet 3, and then through the chamber 2, to discharge it back to atmosphere by way of an outlet 6. The airflow chamber 2 houses a cyclone air/liquid separator 7 through which the inflowing air is caused to pass. An injector 8 introduces liquid into air flowing through the air inlet 3. The cyclone separator 7 extracts this liquid and any entrained particles therein and discharges it from the airflow chamber 2, initially by way of a duct 9, where it is then conveyed to a collection vessel 12, by way of a three channel peristaltic pump 13, and a duct 14. The collection vessel 12 is housed within a Peltier-cooled holder 15 to maintain the contents of the vessel 12 within the 2null C.-8null C. range which is desirable for maintaining the integrity of biological analytes such as bacteria or proteins. Analyses such as PCR, culture on agar plates or immunoassays may be performed on the collected samples. The holder 15 also houses sample bottles 16, 17, 18 and 19.
摘要翻译：参考图1。 1和用于分析生物或其它分析物的空气取样器1包括具有空气入口3和空气出口4的气流室2.来自5的提取物通过入口3吸入环境空气，然后通过室 2，通过出口6将其排放回大气。气流室2容纳旋风分离器空气/液体分离器7，通过该旋风分离器空气/液体分离器7使流入的空气通过。喷射器8将液体引入流过空气入口3的空气中。旋风分离器7将该液体和任何夹带的颗粒提取出来，并将其从气流室2排出，最初通过管道9，然后将其输送到收集容器12，通过三通道蠕动泵13和管道14.收集容器12容纳在珀尔帖冷却的保持器15内，以将容器12的内容物保持在2℃-8℃ 对于保持生物分析物如细菌或蛋白质的完整性是期望的。可以在收集的样品上进行PCR，琼脂平板培养或免疫测定等分析。保持器15还容纳样品瓶16,17,18和19。

33. 发明授权

US06485686B1 Method and apparatus for counting submicron sized particles 有权
标题翻译：亚微米尺寸颗粒计数的方法和装置
公开(公告)号：US06485686B1
公开(公告)日：2002-11-26
申请号：US09662787
申请日：2000-09-15
申请人： Charles Harold Wick
发明人： Charles Harold Wick
IPC分类号： G01N930
CPC分类号： G01N15/1031 , G01N1/2202 , G01N1/2273 , G01N1/40 , G01N1/4077 , G01N15/0255 , G01N15/0272 , G01N15/042 , G01N15/065 , G01N15/1456 , G01N33/48714 , G01N33/497 , G01N2001/2217 , G01N2001/2223 , G01N2001/4066 , G01N2015/1486
摘要： A system for detecting the presence of different size groups of submicron size particles in a fluid sample collected from the environment includes apparatus for collecting the environment. The collected a liquid sample containing submicron size particles selected from the group of viruses, prions, macromolecules, proteins and satellites, is directed to an electrospray assembly having an electrospray capillary for ejecting droplets of the fluid sample under the influence of an electric field. The ejected droplets from the electrospray assembly are directed to a differential mobility analyzer which passes the ejected droplets through an electric field, and the particles are then directed to a condensation particle device for counting the number of particles that pass through the electric field.
摘要翻译：用于检测从环境收集的流体样品中存在不同大小的亚微米尺寸颗粒的系统包括用于收集环境的装置。收集的含有选自病毒，朊病毒，大分子，蛋白质和卫星组的亚微米尺寸颗粒的液体样品被引导到具有用于在电场影响下喷射流体样品的液滴的电喷雾毛细管的电喷雾组件。来自电喷雾组件的喷射的液滴被引导到将喷射的液滴通过电场的差分迁移率分析仪，然后将颗粒引导到用于计数通过电场的颗粒数量的冷凝颗粒装置。

34. 发明申请

US20020062702A1 Vacuum air component sampler 失效
标题翻译：真空空气成分取样器
公开(公告)号：US20020062702A1
公开(公告)日：2002-05-30
申请号：US09728790
申请日：2000-11-30
发明人： Bruce J. Bradley
IPC分类号： G01N001/14 , G01N001/00
CPC分类号： G01N1/2214 , G01N1/2208 , G01N2001/2217 , G01N2001/2223 , G01N2001/248
摘要： The invention is an air sampler which utilizes a hydrophobic filter and an entrapment fluid contained within a sampler body. Air to be sampled is bubbled through the entrapment fluid, which traps and retains a selected air component for later testing. Air which is thus bubbled through the entrapment fluid passes through a hydrophobic filter before leaving the sampler body. A hydrophobic filter prevents aqueous liquids from exiting the sampler body. This allows a higher rate of air flow, because the sampling fluid does not diminish as quickly due to suspended droplets exiting the sampler body. The sampler body may also be inverted to rinse down the walls of the sampler body without losing any liquid, due to the presence of the hydrophobic filter. The entrapment fluid can be poured or drained out of the sampler body.
摘要翻译：本发明是采用疏水过滤器和包含在采样器体内的捕集液的空气取样器。待采样的空气通过捕集流体鼓泡，捕集并保留选定的空气组分供以后测试。在离开采样器主体之前，通过吸引流体鼓泡的空气通过疏水过滤器。疏水过滤器防止含水液体离开采样器主体。这允许更高的空气流速，因为采样流体不会由于离开采样器主体的悬浮液体而快速减少。由于疏水性过滤器的存在，采样器主体也可以倒置以冲洗采样器主体的壁而不会损失任何液体。捕集液可以从采样器体中倒出或排出。

35. 发明授权

US6146591A Biochemical detection system for rapid determination of the presence of toxins, bacteria, and other substances 失效
标题翻译：生化检测系统可快速测定毒素，细菌等物质的存在
公开(公告)号：US6146591A
公开(公告)日：2000-11-14
申请号：US70737
申请日：1998-05-01
申请人： C David Miller
发明人： C David Miller
IPC分类号： G01N1/22 , G01N21/25 , G01N35/02 , G01N35/04 , G01N21/00
CPC分类号： G01N21/253 , G01N35/028 , G01N2001/2217 , G01N2035/0436 , Y10T436/110833 , Y10T436/112499 , Y10T436/113332 , Y10T436/114998 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： This device discloses a portable sequential contaminant detection system which can test samples for contaminants at predetermined timed intervals. The detection system has a motor to advance a matrix, a motor to raise and lower syringes holding liquefied samples of air to be tested, and a motor to raise and lower plungers within the syringes to draw up fluids or expel fluids into reservoir wells of the matrix to test air or other samples for contaminants. The system relies upon a "matrix" which will hold reagents with which the air samples will be mixed. The matrix is stepped to move into precise registration with the "read" module where the relative reflectance of each capture membrane reads statically by a fixed LED, silicon photodiode and amplifier associated with each channel.
摘要翻译：该装置公开了一种便携式顺序污染物检测系统，其可以以预定的时间间隔测试样品的污染物。检测系统具有马达推进矩阵，马达升高和降低保持要测试的空气的液化样品的注射器，以及用于升高和降低注射器内的柱塞的马达，以便将流体排出流体或将流体排出到用于测试空气或其他样品的污染物。该系统依赖于“基质”，其将容纳将与空气样品混合的试剂。矩阵被逐步移动到与“读取”模块的精确配准，其中每个捕获膜的相对反射率由与每个通道相关联的固定LED，硅光电二极管和放大器静态地读取。

36. 发明授权

US5868928A Microbial sampler and concentrator 失效
标题翻译：微生物取样器和浓缩器
公开(公告)号：US5868928A
公开(公告)日：1999-02-09
申请号：US872268
申请日：1997-06-10
申请人： Bruce J. Bradley
发明人： Bruce J. Bradley
IPC分类号： B01D21/26 , C12M1/26 , B01D63/00
CPC分类号： C12M33/04 , B01D21/262 , B01D2221/06 , B01D2221/08 , G01N2001/028 , G01N2001/2217
摘要： A microbial sampling, filtration, and recovery device which utilizes a wash solution on meat carcasses and a vacuum source to vacuum the wash solution and suspended microbes into a collection device. The collection device includes pre-filters for removing debris, and a microbial filter. The filter is small enough to filter out bacteria, and since this size of filter seriously reduces air flow, an alternate route for air is provided through a hydrophobic filter. Bacteria captured on the filter is back-flushed into a collection vessel where it is concentrated in a subsequent centrifuge step. The concentrated microbial sample is available for use in rapid detection methods.
摘要翻译：微生物采样，过滤和回收装置，其利用肉体上的洗涤溶液和真空源将洗涤溶液和悬浮微生物真空吸收到收集装置中。收集装置包括用于去除碎屑的预过滤器和微生物过滤器。过滤器足够小以过滤掉细菌，并且由于这种过滤器的尺寸严重降低了空气流量，所以通过疏水过滤器提供了空气的替代途径。将在过滤器上捕获的细菌回冲入收集容器中，在收集容器中将其浓缩在随后的离心机步骤中。浓缩的微生物样品可用于快速检测方法。

37. 发明授权

US5328851A High-throughput liquid-absorption preconcentrator sampling methods 失效
标题翻译：高通量液体吸收预浓缩器取样方法
公开(公告)号：US5328851A
公开(公告)日：1994-07-12
申请号：US993080
申请日：1992-12-18
申请人： Solomon Zaromb
发明人： Solomon Zaromb
IPC分类号： G01N1/02 , G01N1/22 , G01N1/24 , G01N1/34 , G01N30/00 , G01N30/06 , G01N30/14 , G01N1/18 , G01N35/08
CPC分类号： G01N1/34 , G01N1/2205 , G01N30/00 , G01N30/06 , G01N1/2214 , G01N1/24 , G01N1/405 , G01N2001/022 , G01N2001/2217 , G01N2001/4016 , G01N2030/146 , Y10T436/117497 , Y10T436/255
摘要： A system for detecting trace concentrations of an analyte in air includes a preconcentrator for the analyte and an analyte detector. The preconcentrator includes an elongated tubular container comprising a wettable material. The wettable material is continuously wetted with an analyte-sorbing liquid which flows from one part of the container to a lower end. Sampled air flows through the container in contact with the wetted material with a swirling motion which results in efficient transfer of analyte vapors or aerosol particles to the sorbing liquid and preconcentration of traces of analyte in the liquid. The preconcentrated traces of analyte may be either detected within the container or removed therefrom for injection into a separate detection means or for subsequent analysis.
摘要翻译：用于检测空气中分析物的微量浓度的系统包括用于分析物的预浓缩器和分析物检测器。预浓缩器包括细长的管状容器，其包括可润湿的材料。可湿性材料用从容器的一部分流向下端的分析物吸附液连续地润湿。取样的空气以与旋转运动接触的容器流动，这导致分析物蒸汽或气溶胶颗粒有效转移到吸附液体中，并且浓缩液体中痕量的分析物。分析物的预浓缩痕迹可以在容器内检测或从其中移出，用于注射到单独的检测装置中或用于随后的分析。

38. 发明授权

US5302191A Denuder for gas sampling 失效
标题翻译：取样器用于气体取样
公开(公告)号：US5302191A
公开(公告)日：1994-04-12
申请号：US938854
申请日：1992-09-01
申请人： Petros Koutrakis , Stephen T. Ferguson , Jack M. Wolfson
发明人： Petros Koutrakis , Stephen T. Ferguson , Jack M. Wolfson
IPC分类号： B01D50/00 , B01D51/10 , G01N1/22 , B01D46/24
CPC分类号： B01D51/10 , B01D50/002 , G01N1/2205 , G01N1/2214 , G01N2001/2217 , G01N2001/2223
摘要： A denuder for collection of gases, consisting of a plurality of generally parallel elongated tubes having a surface formed from an inert non-metallic material, said tubes being configured and arranged to allow recovery of gaseous material collected on each said surface.
摘要翻译：一种用于收集气体的分解器，由多个具有由惰性非金属材料形成的表面的大致平行的细长管组成，所述管被构造和布置成允许回收在每个所述表面上收集的气态物质。

39. 发明授权

US5301536A Apparatus for obtaining on-line gas samples for the measurement of crude oil content 失效
标题翻译：用于获取在线气体样品用于测量原油含量的装置
公开(公告)号：US5301536A
公开(公告)日：1994-04-12
申请号：US928289
申请日：1992-08-12
申请人： Pedro Ortega , Fernando Cassani , Enrique Poleo , Daniel Fernandez
发明人： Pedro Ortega , Fernando Cassani , Enrique Poleo , Daniel Fernandez
IPC分类号： F17D3/10 , G01N1/22 , G01N1/40 , G01N33/00 , G01N33/28 , B01D53/00 , B01D57/00 , G01N21/75 , G01N31/00
CPC分类号： G01N33/0016 , F17D3/10 , G01N1/2247 , G01N1/40 , G01N33/2823 , G01N2001/2217 , G01N2001/2267 , G01N2001/4033
摘要： The present invention is drawn to a method for measuring crude oil contained in a gas flowing in a gas line which incorporates the steps of obtaining a sample of gas from the gas line, passing the sample of gas through a selective crude oil trap, measuring the volume of the sample of gas, and measuring the volume of trapped crude oil. The selective crude oil trap includes a cooled coil and at least one cylinder filled with a fluid which is non-soluble with oil and which is preferably refrigerated. The selective crude oil trap may alternatively include a filter device which has a cylinder filled with a polymerized porous medium bound with a phenolic resin. The apparatus for carrying out the method has inlet and outlet connectors which allow the apparatus to be releasably connected to a gas flow line to obtain a sample of gas and to be disconnected and physically transported to a remote facility for completion of the testing.
摘要翻译：本发明涉及用于测量在气体管线中流动的气体中所含的原油的方法，该方法包括以下步骤：从气体管线获得气体样品，使气体样品通过选择性原油阱，测量气体样品的体积，并测量被捕原油的体积。选择性原油捕集器包括冷却的盘管和至少一个填充有不可溶于油并且优选冷藏的流体的气缸。选择性原油阱可以可选地包括过滤器装置，其具有填充有与酚醛树脂结合的聚合多孔介质的圆筒。用于执行该方法的装置具有入口和出口连接器，其允许装置可释放地连接到气体流动管线以获得气体样本并被断开并物理地运输到远程设施以完成测试。

40. 发明授权

US5131260A Device and method for the continuous measurement of the ammonia concentration in gases in the ppm range 失效
标题翻译：在PPM范围内连续测量气体浓度的装置和方法
公开(公告)号：US5131260A
公开(公告)日：1992-07-21
申请号：US676707
申请日：1991-03-29
申请人： Reinhold Brand , Bernd Engler , Wolfgang Honen , Edgar Koberstein
发明人： Reinhold Brand , Bernd Engler , Wolfgang Honen , Edgar Koberstein
IPC分类号： G01N31/00 , G01N1/22 , G01N1/34 , G01N1/40 , G01N33/00
CPC分类号： G01N1/405 , G01N1/2258 , G01N33/0054 , G01N2001/2217 , G01N2001/2282 , G01N2001/4033
摘要： A device for the continuous measurement of the ammonia concentration in gases in the ppm range includes a columnar absorption vessel (1) with a hemispherical bottom (4). The bottom of the column includes an overflow (3) and an outlet (5). The gas introduction pipe (7,8) empties above the bottom (4) and below a sieve bottom (6) arranged in the column (1). A packing material (10) rests on the sieve bottom (6), which packing (10) essentially fills the absorption column (1). A cooling part (11) extends from the absorption column (1). The cooling part (11) includes a cooling zone (15) and a gas collection space (16) above it with a closable connection piece (13). A pipe (14), which may include a serrated crown on each end, runs from the gas collecting space (16) downward in a cooled manner to the packing 10. The liquid absorption agent is introduced through a lateral connection piece (18) into the gas collection space (16). For the measurement of ammonia concentration, a certain volume flow of the gas to be measured is washed in a countercurrent flow with the absorption agent, and the NH.sub.3 content is determined in a part of the ammonia containing absorption agent. The volume flow rate of the absorption agent and of the gas from which NH.sub.3 has been removed is measured (the latter being dried), and the ammonia concentration is thereby calculated.
摘要翻译：在ppm范围内连续测量气体中的氨浓度的装置包括具有半球形底部（4）的柱状吸收容器（1）。塔的底部包括溢流（3）和出口（5）。气体导入管（7,8）在布置在塔（1）中的底部（4）和下方的筛底（6）之上排空。包装材料（10）搁置在筛底（6）上，该填料（10）基本上填充吸收塔（1）。冷却部件（11）从吸收塔（1）延伸。冷却部件（11）在其上方包括一个冷却区（15）和一个气体收集空间（16），并具有可关闭的连接件（13）。可以在每个端部包括锯齿状冠的管道（14）从气体收集空间（16）以冷却的方式向下延伸到填料10.液体吸收剂通过横向连接件（18）引入气体收集空间（16）。为了测量氨浓度，将要测量的气体的一定体积流量与吸收剂以逆流流动洗涤，并且在含氨吸收剂的一部分中测定NH 3含量。测量吸收剂和从其中除去NH 3的气体的体积流量（后者被干燥），由此计算氨浓度。

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