会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 36. 发明申请
    • Bioactive graded zirconia-based structures
    • 生物活性分级氧化锆基结构
    • US20090118114A1
    • 2009-05-07
    • US12284620
    • 2008-09-22
    • Yu ZhangRacquel RegerosJae-Won Kim
    • Yu ZhangRacquel RegerosJae-Won Kim
    • C04B35/053
    • C04B41/5022A61L27/10A61L27/427C04B41/009C04B41/86C04B2111/00405C04B2111/00836C04B41/4539C04B41/4535C04B41/455C04B35/10C04B35/119C04B35/48C04B35/488
    • The present invention provides a functionally graded bioactive glass/ceramic composite structure or bioactive glass/ceramic/bioactive glass sandwich structure for use in such applications as damage resistant, ceramic dental implants, immediate tooth replacement, endodontic posts, orthopedic prostheses, orthopedic stems, bone substitutes, bone screws, plates, and anchors, nonunion fractures repair, alveolar ridge augmentation, missing small bone parts (e.g. fingers, toes, etc), maxilla facial reconstruction, spinal fusion, and scaffolds for bone regeneration, comprising a residual bioactive glass or glass-ceramic layer at all accessible surfaces, followed by an underlying graded glass-ceramic layer, and then an dense interior ceramic. The residual bioactive glass or glass-ceramic layer can be further transformed to a carbonate apatite (CHA) layer by immersing in calcifying solution or simulated body fluid (SBF) with electrolyte composition similar to that of serum. The interior ceramic preferably contains yttria-tetragonal zirconia polycrystal (Y-TZP) or ceria stabilized tetragonal zirconia polycrystal (Ce-TZP) or magnesia stabilized zirconia (Mg-PSZ) or calcia stabilized zirconia (Ca-PSZ) or alumina or zirconia-alumina composites. Further, the invention provides methods for making the same functionally graded bioactive glass/ceramic composite structure or graded bioactive glass/ceramic/bioactive glass sandwich structure.
    • 本发明提供功能梯度的生物活性玻璃/陶瓷复合结构或生物活性玻璃/陶瓷/生物活性玻璃夹层结构,用于诸如耐损伤陶瓷牙科植入物,立即牙齿置换,牙髓根管,矫形假体,矫形骨,骨骼 替代物,骨螺钉,板和锚,不愈合骨折修复,牙槽嵴隆起,缺少小骨部分(例如手指,脚趾等),上颌面部重建,脊柱融合和用于骨再生的支架,包括残留生物活性玻璃或 玻璃陶瓷层,随后是下层玻璃陶瓷层,然后是密集的内部陶瓷。 残留的生物活性玻璃或玻璃陶瓷层可以通过浸入含钙血浆或模拟体液(SBF)的电解质组成与血清类似的碳酸钙磷灰石(CHA)层。 内部陶瓷优选含有氧化钇 - 四方晶氧化锆多晶(Y-TZP)或二氧化铈稳定的四方晶氧化锆多晶(Ce-TZP)或氧化镁稳定的氧化锆(Mg-PSZ)或氧化钙稳定的氧化锆(Ca-PSZ)或氧化铝或氧化锆 - 氧化铝 复合材料。 此外,本发明提供了制造相同功能梯度生物活性玻璃/陶瓷复合结构或分级生物活性玻璃/陶瓷/生物活性玻璃夹心结构的方法。