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31. 发明申请

US20150086662A1 EMBELIA CONCINNA EXTRACT COMPRISING FLAVONOIDS IN COSMETIC AND PHARMACEUTICAL COMPOSITIONS 有权
标题翻译：化妆品和药物组合物中包含香草素的EMBELIA CONCINNA提取物
公开(公告)号：US20150086662A1
公开(公告)日：2015-03-26
申请号：US14394268
申请日：2013-04-10
申请人： BAYER CONSUMER CARE AG
发明人： Virginie Petit , Eric Theron
IPC分类号： A61K36/185 , A61Q19/00 , A61K45/06 , A61K8/97 , A61K31/352 , A61K31/7048
CPC分类号： A61K36/185 , A61K8/345 , A61K8/498 , A61K8/602 , A61K8/97 , A61K31/352 , A61K31/7048 , A61K45/06 , A61K47/10 , A61K2236/333 , A61K2800/75 , A61K2800/805 , A61Q19/00 , A61Q19/005
摘要： The present invention deals with an Embelia extract—preferably an extract from Embelia concinna titrated in flavonoids—, its process for preparation and its use in a cosmetical or pharmaceutical composition for the treatment of skin sensitivity, for the treatment of allergic reactions of the skin, for soothing and for the treatment of itching skin and for the regulation of inflammatory drifts in the skin.
摘要翻译：本发明涉及一种Embelia提取物，优选地是以类黄酮滴定的Embelia concinna的提取物，其制备方法及其在美容或药物组合物中用于治疗皮肤敏感性，用于治疗皮肤过敏反应的提取物，用于舒缓和治疗皮肤瘙痒和调节皮肤炎症漂移。

32. 发明申请

US20150051296A1 USE OF FATTY ACID TO REDUCE SKIN IRRITATION ASSOCIATED WITH RETINOID THERAPY 审中-公开
标题翻译：使用脂肪酸减少与复发治疗相关的皮肤刺激
公开(公告)号：US20150051296A1
公开(公告)日：2015-02-19
申请号：US14454146
申请日：2014-08-07
申请人： John F. Rebhun , Rodney A. Velliquette , Samantha Westveer
发明人： John F. Rebhun , Rodney A. Velliquette , Samantha Westveer
IPC分类号： A61K8/36 , A61Q19/08 , A61Q19/00 , A61K8/34
CPC分类号： A61K8/361 , A61K8/342 , A61K8/671 , A61K2800/70 , A61K2800/75 , A61Q19/00 , A61Q19/08
摘要： A composition and a method that is effective to reduce, limit, or diminish one or more side effects of a retinoid are described. The composition includes a retinoid and a free fatty acid. The composition may further include one or more cosmetically suitable ingredients so long as they do not interfere with the efficaciousness of the free fatty acid. The method for reducing, limiting, or diminishing a side effect associated with the topical administration of a retinoid to a skin area of a subject includes topically administering a free fatty acid to the skin area prior to, during, and/or after topical administration of the retinoid.
摘要翻译：描述了有效减少，限制或减少类视黄醇的一种或多种副作用的组合物和方法。组合物包含类视色素和游离脂肪酸。组合物可以进一步包括一种或多种美容上合适的成分，只要它们不干扰游离脂肪酸的有效性即可。用于减少，限制或减少与类视黄醇局部给予受试者皮肤区域的副作用的方法包括在局部施用之前，期间和/或之后向皮肤区域局部施用游离脂肪酸，类视黄醇

33. 发明申请

US20150045420A1 SKIN CARE COMPOSITIONS HAVING CYCLIC DIESTERS AND METHODS THEREOF 审中-公开
公开(公告)号：US20150045420A1
公开(公告)日：2015-02-12
申请号：US14455115
申请日：2014-08-08
申请人： E I DU PONT DE NEMOURS AND COMPANY
发明人： WILLIAM R. CAHILL, JR. , Robert Ray Burch , Jeffrey Jon Horsager , Jessica Linda Reisack , Jennifer Marie Altland
IPC分类号： A61K8/49 , A61Q19/00
CPC分类号： A61K8/498 , A61K8/31 , A61K8/375 , A61K8/4973 , A61K2800/31 , A61K2800/75 , A61Q19/00 , A61Q19/007
摘要： The present invention generally relates to topical skin care compositions having at least one cyclic diester. More specifically, the present invention relates to novel topical skin care compositions having at least one cyclic diester of an alpha hydroxy acid, and at least one polar non-aqueous solvent.

34. 发明申请

US20150038457A1 COMPOSITION COMPRISING HYALURONIC ACID AND MEPIVACAINE 有权
标题翻译：包含羟丙酸和去乙酰胺的组合物
公开(公告)号：US20150038457A1
公开(公告)日：2015-02-05
申请号：US13954360
申请日：2013-07-30
申请人： Teoxane
发明人： Francois Bourdon , Stephane Meunier
IPC分类号： A61K31/445 , A61K31/16
CPC分类号： A61L27/54 , A61K8/24 , A61K8/4926 , A61K8/735 , A61K9/0019 , A61K9/0024 , A61K31/16 , A61K31/167 , A61K31/445 , A61K31/451 , A61K31/728 , A61K47/02 , A61K2800/524 , A61K2800/75 , A61K2800/91 , A61L27/12 , A61L27/20 , A61L2300/204 , A61L2300/402 , A61L2400/06 , A61Q19/08 , A61K2300/00
摘要： Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
摘要翻译：提供了一种用于皮肤受试者表面外观的组合物和方法。一种至少含有透明质酸或其盐的可注射组合物; 并提供有效量的至少甲哌卡因或其盐。透明质酸任选地具有50,000至10,000,000道尔顿的平均分子量，并且在一些实施方案中可以是交联的透明质酸，非交联透明质酸或组合。本发明的组合物和方法可用于治疗和预防皮肤老化迹象和/或外部因素如应激，空气污染，烟草或长时间暴露于紫外线（UV）暴露，受损的表面外观，皮肤，皮肤受损的粘弹性或生物力学性质，和/或皮肤体积缺陷的持久的填充。

35. 发明申请

US20140373864A1 AQUEOUS OXIDIZING COMPOSITION 有权
标题翻译：水分氧化组合物
公开(公告)号：US20140373864A1
公开(公告)日：2014-12-25
申请号：US14368682
申请日：2012-12-20
申请人： KAO GERMANY GMBH
发明人： Jürgen Ehmig , Sandra Schmelz , Martin Uellner
IPC分类号： A61K8/49 , A61Q5/10
CPC分类号： A61K8/4946 , A61K2800/4324 , A61K2800/75 , A61K2800/882 , A61Q5/10
摘要： Present invention relates to an oxidative dyeing composition having especially mild properties to the scalp. The object of the present invention is an oxidative dyeing composition for hair comprising at least one dyestuff and allantoin and/or its derivative.
摘要翻译：本发明涉及对头皮具有特别温和性质的氧化染色组合物。本发明的目的是一种用于头发的氧化染色组合物，其包含至少一种染料和尿囊素和/或其衍生物。

36. 发明授权

US08858968B2 Use of tyrosine-arginine dipeptide and niacinamide as substance P antagonist 有权
标题翻译：使用酪氨酸 - 精氨酸二肽和烟酰胺作为P物质拮抗剂
公开(公告)号：US08858968B2
公开(公告)日：2014-10-14
申请号：US11566708
申请日：2006-12-05
申请人： Anthony Potin
发明人： Anthony Potin
IPC分类号： A61K8/64 , A61K8/49 , A61Q19/00 , A61K38/05 , A61K8/67 , A61Q7/00
CPC分类号： A61K8/675 , A61K8/64 , A61K38/05 , A61K2800/75 , A61Q7/00 , A61Q19/00 , A61Q19/005 , A61K2300/00
摘要： Use of the combination of the tyrosine-arginine dipeptide or derivatives thereof and of niacinamide as a substance P antagonist for treating red blotches on the skin, skin oedema and sensitive skin. Use of this combination for the preparation of a composition for use in treating disorders associated with an excess synthesis and/or release of substance P.
摘要翻译：使用酪氨酸 - 精氨酸二肽或其衍生物和烟酰胺作为物质P拮抗剂的组合来治疗皮肤上的红斑，皮肤水肿和敏感皮肤。使用这种组合来制备用于治疗与物质P的过量合成和/或释放有关的疾病的组合物。

37. 发明授权

US08840869B2 Body cavity foams 有权
标题翻译：体腔泡沫
公开(公告)号：US08840869B2
公开(公告)日：2014-09-23
申请号：US11116761
申请日：2005-04-28
申请人： Doron Friedman , Alex Besonov , Dov Tamarkin , Meir Eini
发明人： Doron Friedman , Alex Besonov , Dov Tamarkin , Meir Eini
IPC分类号： A61K8/00 , A61Q19/04 , A61K9/12 , A61Q7/00 , A61Q19/02 , A61K8/60 , A61Q17/02 , A61K9/00 , A61Q17/04 , A61K9/46 , A61K8/04 , A61Q7/02
CPC分类号： A61K47/46 , A01N25/16 , A61K8/046 , A61K8/60 , A61K9/0007 , A61K9/0014 , A61K9/0034 , A61K9/107 , A61K9/12 , A61K9/122 , A61K31/137 , A61K31/351 , A61K31/4164 , A61K31/4174 , A61K31/522 , A61K31/535 , A61K31/567 , A61K31/573 , A61K31/7036 , A61K31/7048 , A61K38/12 , A61K38/212 , A61K47/10 , A61K47/14 , A61K47/20 , A61K47/26 , A61K47/34 , A61K47/38 , A61K2800/75 , A61Q7/00 , A61Q7/02 , A61Q17/02 , A61Q17/04 , A61Q19/02 , A61Q19/04
摘要： The invention relates to an alcohol-free cosmetic or therapeutic foam carrier comprising water, a hydrophobic organic carrier, a foam adjuvant agent, a surface-active agent and a gelling agent. The cosmetic or therapeutic foam carrier does not contain aliphatic alcohols, making it non-irritating and non-drying. The alcohol-free foam carrier is suitable for inclusion of both water-soluble and oil soluble therapeutic and cosmetic agents.
摘要翻译：本发明涉及包含水，疏水性有机载体，泡沫助剂，表面活性剂和胶凝剂的无醇化妆品或治疗泡沫载体。化妆品或治疗泡沫载体不含脂肪醇，使其不刺激和不干燥。无醇泡沫载体适合包含水溶性和油溶性治疗和美容剂。

38. 发明申请

US20140235577A1 EXTERNAL SKIN AGENT COMPRISING MODIFIED CLAY FOR PREVENTING INFLAMMATION 审中-公开
标题翻译：包含改性粘土以防止炎症的外用皮肤试剂
公开(公告)号：US20140235577A1
公开(公告)日：2014-08-21
申请号：US14244600
申请日：2014-04-03
申请人： Taisho Pharmaceutical Co., Ltd. , Pola Chemical Industries Inc.
发明人： Yasuhiro Ohara , Masashi SUZUKI , Norikazu Takano , Shunpei Mitsuyama
IPC分类号： A61K31/695 , A61K31/56
CPC分类号： A61K31/695 , A61K8/26 , A61K8/416 , A61K8/891 , A61K9/0014 , A61K31/56 , A61K33/06 , A61K35/02 , A61K47/32 , A61K47/34 , A61K2800/75 , A61Q17/00 , A61K2300/00
摘要： To provide An external skin agent that prevents onset of atopic skin inflammations and is low irritant to skin, which is characterized by including: 1) clay modified by a compound having a quaternary amino group; and 2) a polymer or copolymer that has a side chain including a structure similar to a biological component.
摘要翻译：提供防止特应性皮肤炎症发作的皮肤外用剂，对皮肤的刺激性低，其特征在于包括：1）由具有季氨基的化合物改性的粘土; 和2）具有包含类似于生物组分的结构的侧链的聚合物或共聚物。

39. 发明授权

US08790631B2 Use of biocompatible polymers for the preparation of a composition or a medical device 有权
标题翻译：使用生物相容性聚合物制备组合物或医疗器械
公开(公告)号：US08790631B2
公开(公告)日：2014-07-29
申请号：US10577637
申请日：2004-10-28
申请人： Denis Barritault , Veronique Barbier-Chassefiere
发明人： Denis Barritault , Veronique Barbier-Chassefiere
IPC分类号： A61K31/716
CPC分类号： A61Q17/00 , A61K8/73 , A61K8/731 , A61K8/733 , A61K31/737 , A61K31/795 , A61K2800/75 , A61Q19/00
摘要： The invention relates to a biocompatible polymer having general formula (I) AaXxYy, wherein: A denotes a monomer; X denotes an RCOOR′ group; Y denotes an O or N-sulphonate group which is fixed to A and which has either formula —ROS03R′ or —RNS03R′ in which R denotes an optionally branched and/or unsaturated aliphatic hydrocarbon chain which can contain one or more aromatic rings and R′ denotes a hydrogen atom or a cation; a denotes the number of monomers; x denotes the rate of substitution of the A monomers by the X groups; and y denotes the rate of substitution of the A monomers by the Y groups. More specifically, the invention relates to the use of said biocompatible polymers for the preparation of a pharmaceutical, dermatological or cosmetic composition or a medical device, which are intended to prevent, relieve and/or treat discomfort, distress, itches, irritations and/or pain and/or to protect tissues against same. In addition, in certain cases, the use of said biocompatible polymers for pain treatment can impact on the actual curing of certain diseases. Significant improvements and even cures have been observed in relation to chronic and painful diseases that are associated with alterations in the extracellular matrix regardless of the origin thereof.
摘要翻译：本发明涉及具有通式（I）A a X x Y y的生物相容性聚合物，其中：A表示单体; X表示RCOOR'基团; Y表示固定在A上并具有式-ROS03R'或-RNS03R'的O或N-磺酸盐基团，其中R表示可含有一个或多个芳环的任选支链和/或不饱和脂族烃链，R '表示氢原子或阳离子; a表示单体数目; x表示X单体的A单体的取代率; y表示Y单体由Y基取代的比例。更具体地，本发明涉及所述生物相容性聚合物用于制备药物，皮肤病学或化妆品组合物或医疗装置的用途，其旨在防止，缓解和/或治疗不适，痛苦，瘙痒，刺激和/或疼痛和/或保护组织免受同样的影响。此外，在某些情况下，使用所述生物相容性聚合物进行疼痛治疗可能会影响某些疾病的实际固化。对于与细胞外基质的改变相关的慢性和疼痛性疾病，观察到显着的改善甚至治愈，不管其来源如何。

40. 发明授权

US08741323B2 External skin agent comprising modified clay for preventing inflammation 有权
标题翻译：包含用于预防炎症的改性粘土的外用皮肤剂
公开(公告)号：US08741323B2
公开(公告)日：2014-06-03
申请号：US11722338
申请日：2005-11-25
申请人： Yasuhiro Ohara , Masashi Suzuki , Norikazu Takano , Shunpei Mitsuyama
发明人： Yasuhiro Ohara , Masashi Suzuki , Norikazu Takano , Shunpei Mitsuyama
IPC分类号： A61Q19/00
CPC分类号： A61K31/695 , A61K8/26 , A61K8/416 , A61K8/891 , A61K9/0014 , A61K31/56 , A61K33/06 , A61K35/02 , A61K47/32 , A61K47/34 , A61K2800/75 , A61Q17/00 , A61K2300/00
摘要： To provide An external skin agent that prevents onset of atopic skin inflammations and is low irritant to skin, which is characterized by including: 1) clay modified by a compound having a quaternary amino group; and 2) a polymer or copolymer that has a side chain including a structure similar to a biological component.
摘要翻译：提供防止特应性皮肤炎症发作的皮肤外用剂，对皮肤的刺激性低，其特征在于包括：1）由具有季氨基的化合物改性的粘土; 和2）具有包含类似于生物组分的结构的侧链的聚合物或共聚物。

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