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31. 发明申请

US20140276103A1 MEDICAL IMAGING DEVICE AND METHODS OF USE 审中-公开
公开(公告)号：US20140276103A1
公开(公告)日：2014-09-18
申请号：US14211259
申请日：2014-03-14
申请人： Lumicell, Inc.
发明人： W. David Lee , Jorge Ferrer , David B. Strasfeld
IPC分类号： A61B5/00
CPC分类号： A61B5/0091 , A61B5/0071 , A61B5/0075 , A61B5/0086 , A61B5/4312 , A61B5/6886 , A61B10/0041 , A61B90/361 , A61B2090/306 , A61B2090/309 , A61B2090/3616 , A61B2090/3941 , A61B2505/05 , A61B2560/0431 , A61K49/0032 , A61K49/0056
摘要： Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.

32. 发明申请

US20140213895A1 RADIATION IMAGE DISPLAY METHOD AND APPARATUS 审中-公开
标题翻译：辐射图像显示方法和装置
公开(公告)号：US20140213895A1
公开(公告)日：2014-07-31
申请号：US14229256
申请日：2014-03-28
申请人： FUJIFILM CORPORATION
发明人： Takao KUWABARA , Yasuko YAHIRO , Yasunori OHTA , Akira HASEGAWA
IPC分类号： A61B5/06 , A61B5/00
CPC分类号： A61B5/061 , A61B5/0091 , A61B6/022 , A61B6/025 , A61B6/0414 , A61B6/12 , A61B6/463 , A61B6/466 , A61B6/469 , A61B6/502 , A61B6/5235 , A61B10/0041 , A61B10/0233
摘要： Two radiation images are acquired by emitting radiation to a subject from two imaging directions that form a first imaging angle, and two radiation images are acquired imaged from two imaging directions that form a second imaging angle. The radiation images of the first imaging angle are displayed as two-dimensional images while the radiation images of the second imaging angle are displayed as a stereoscopic image. Designation of a predetermined position in the radiation images that are displayed as two-dimensional images is received to obtain position information. The obtained position information in the radiation images of the first imaging angle is projected onto the radiation images of the second imaging angle based on the position information and three-dimensional position information is obtained. Based on the three-dimension position information, markers are displayed on the radiation images of the second imaging angle which are displayed as a stereoscopic image.
摘要翻译：通过从形成第一成像角度的两个成像方向向对象发射辐射来获取两个辐射图像，并且从形成第二成像角度的两个成像方向拍摄两个辐射图像。将第一成像角度的放射线图像显示为二维图像，而将第二成像角度的放射线图像显示为立体图像。接收用于显示为二维图像的放射线图像中的预定位置的指定以获得位置信息。将获得的第一成像角度的放射线图像中的位置信息基于位置信息投影到第二成像角度的放射线图像上，并获得三维位置信息。基于三维位置信息，将标记显示在作为立体图像显示的第二成像角度的放射线图像上。

33. 发明申请

US20140135620A1 BIOMETRIC APPARATUS AND IMAGE-GENERATING METHOD 有权
标题翻译：生物量装置和图像生成方法
公开(公告)号：US20140135620A1
公开(公告)日：2014-05-15
申请号：US14130690
申请日：2012-06-28
申请人： Hiroyuki Kudo , Naoya Saito , Yukio Ueda , Kenji Yoshimoto , Yutaka Yamashita
发明人： Hiroyuki Kudo , Naoya Saito , Yukio Ueda , Kenji Yoshimoto , Yutaka Yamashita
IPC分类号： A61B5/00 , A61B8/15
CPC分类号： A61B5/7203 , A61B5/0073 , A61B5/0082 , A61B6/5247 , A61B8/15 , A61B8/5207 , A61B10/0041 , G01N21/4795 , G06T11/006
摘要： The bioinstrumentation apparatus includes a light irradiation unit irradiating a measurement region with light, a light detection unit detecting diffused light from the measurement region, and a computing unit generating a reconstructed image for the interior of the measurement region. The computing unit calculates J coefficients wj set for every pixel of the reconstructed image and more than 0 and not more than 1 (where J is the number of pixels of the reconstructed image) and carries out successive approximation computation by the following iterative formula xj(k+1)=xj(k)+wjdj(k) (where k is an integer from 1 to N, N is the number of times of iterative computation, xj(k) is a pixel value of the jth pixel on the kth iterative computation, and dj(k) is an update amount of the jth pixel on the kth iterative computation) to generate the reconstructed image.
摘要翻译：生物仪器装置包括用光照射测量区域的光照射单元，检测来自测量区域的漫射光的光检测单元和产生测量区域内部的重建图像的计算单元。计算单元计算对于重构图像的每个像素设置的J个系数wj，大于0且不大于1（其中J是重构图像的像素数），并且通过以下迭代公式xj执行逐次逼近计算 k + 1）= xj（k）+ wjdj（k）（其中k是从1到N的整数，N是迭代计算的次数，xj（k）是第k个像素的像素值迭代计算，并且dj（k）是第k次迭代计算中的第j个像素的更新量）以生成重构图像。

34. 发明申请

US20140030799A1 APPARATUS FOR DETECTING TUMOR CELLS 有权
标题翻译：检测肿瘤细胞的装置
公开(公告)号：US20140030799A1
公开(公告)日：2014-01-30
申请号：US14110759
申请日：2012-05-04
申请人： Chris C. Yu , Xuedong Du , He Yu
发明人： Chris C. Yu , Xuedong Du , He Yu
IPC分类号： G01N33/50 , C12Q1/68
CPC分类号： G01N33/574 , A61B5/07 , A61B5/14503 , A61B5/1451 , A61B5/14517 , A61B5/14528 , A61B5/14546 , A61B10/0041 , A61B2562/028 , A61B2562/12 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0652 , B01L2200/0663 , B01L2200/0668 , B01L2300/0627 , B01L2300/0636 , B01L2300/0645 , B01L2300/0681 , B01L2300/0858 , B01L2300/0887 , B01L2300/123 , B01L2300/163 , B01L2400/0487 , C12Q1/68 , G01N1/34 , G01N1/4077 , G01N15/1056 , G01N15/1484 , G01N33/487 , G01N33/5091 , G01N33/54366 , G01N2001/4088 , G01N2015/0065 , G01N2015/1006 , G01N2015/1062 , G01N2015/1486
摘要： Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro-chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio-electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination thereof, of the biologic subject.
摘要翻译：其中，本发明提供了一种检测循环肿瘤细胞的装置，包括系统递送生物体和探测和检测装置，其中探测和检测装置包括第一微器件和支撑第一微器件的第一基片，第一微型装置接触待检测的生物材料，并且能够在微观层面上测量电，磁，电磁，热，光，声，生物，化学，机电，电化学，电光学，电热，电化学机械，生物化学，生物机械，生物光学，生物热，生物物理，生物电机械，生物电化学，生物电光学，电热，生物机械光学，生物机械热学，生物热光学，生物电化学光学，生物机电光学，生物电热光学，生物电化学机械，物理或机械 rty或其组合。

35. 发明申请

US20130231586A1 MRI BIOPSY APPARATUS INCORPORATING A SLEEVE AND MULTI-FUNCTION OBTURATOR 审中-公开
标题翻译：装有多功能多功能电脑的MRI生物仪器
公开(公告)号：US20130231586A1
公开(公告)日：2013-09-05
申请号：US13869273
申请日：2013-04-24
申请人： DEVICOR MEDICAL PRODUCTS, INC.
发明人： Mark Tsonton , Timothy G. Dietz , John A. Hibner , Jessica Pyzoha Leimbach , Michael J. Andreyko , Keshava Datta , Michael A. Murray
IPC分类号： A61B10/02 , A61B5/055
CPC分类号： A61B10/02 , A61B5/055 , A61B5/0555 , A61B10/0041 , A61B10/0233 , A61B10/0275 , A61B10/0283 , A61B17/3403 , A61B17/3417 , A61B17/3421 , A61B90/11 , A61B90/17 , A61B2010/0208 , A61B2010/0225 , A61B2017/00477 , A61B2017/00796 , A61B2017/00911 , A61B2017/3411 , A61B2090/034 , A61B2090/036 , A61B2090/374 , A61B2090/3908 , A61B2090/3933 , A61B2090/3954 , A61B2090/3987
摘要： An apparatus for use with a minimally invasive medical procedure into human breast tissue includes a cannula and an obturator. The cannula includes an open distal end, a lateral opening proximate to the open distal end, and a longitudinal lumen communicating with the lateral opening and the open distal end. The lumen has a non-circular cross-section. The obturator is sized for insertion into the cannula. The obturator has a distal end extending from the open distal end of the cannula when the obturator is inserted fully into the cannula. The obturator has a recess proximate of the distal end of the obturator. The recess is positioned along a portion of the length of the obturator to align with the lateral opening of the cannula when the obturator is inserted fully into the cannula.
摘要翻译：将用于微创医疗程序用于人乳房组织的装置包括套管和闭孔器。套管包括敞开的远端，靠近开口远端的侧向开口，以及与侧向开口和开口远端连通的纵向腔。内腔具有非圆形横截面。闭孔器的尺寸适于插入插管。当闭塞器完全插入插管中时，闭塞器具有从插管的开放远端延伸的远端。闭塞器具有靠近密封件远端的凹陷。当闭塞器完全插入插管中时，凹部沿密封件的长度的一部分定位，以与插管的侧向开口对齐。

36. 发明申请

US20130123831A1 TEMPORARY CATHETER FOR BIOPSY SITE TISSUE FIXATION 审中-公开
标题翻译：用于生物场地组织固定的临时导管
公开(公告)号：US20130123831A1
公开(公告)日：2013-05-16
申请号：US13708216
申请日：2012-12-07
申请人： SENORX, INC.
发明人： Paul Lubock , Michael L. Jones
IPC分类号： A61M29/02 , A61M29/00
CPC分类号： A61M29/02 , A61B10/0041 , A61B17/0218 , A61B90/02 , A61B2017/00557 , A61B2017/00796 , A61B2090/3908 , A61M25/10 , A61M29/00 , A61M2025/1095 , A61N5/1015
摘要： Devices and methods are provided for temporarily maintaining access to a body cavity in a targeted tissue region within a patient's body. A catheter for temporarily at least partially filing a body cavity in a targeted tissue region within a patient's body includes a shaft having a distal end, a proximal end, and a cavity filling member on a distal shaft section configured to at least partially fill the body cavity. A proximal shaft section is configured to be folded so as to be subcutaneously deployed within the patient when the cavity filling member is disposed within the body cavity so as to prevent intrusion of bacteria. An anti-bacterial material is applied to or incorporated within a surface of the shaft and the cavity filling member so as to prevent bacteria growth.
摘要翻译：提供了用于暂时维持对患者体内的目标组织区域中的体腔的访问的装置和方法。用于临时至少部分地将患者身体内的目标组织区域中的体腔填充的导管包括：轴，其具有远侧末端，远端轴部分上的空腔填充构件，构造成至少部分地填充身体腔。近端轴部被配置为当空腔填充构件设置在体腔内时被折叠成皮下部署在患者体内，以防止细菌侵入。将抗菌材料施加到或结合在轴和空腔填充构件的表面内，以防止细菌生长。

37. 发明授权

US08419656B2 Post decompression marker introducer system 有权
标题翻译：后减压标记导引系统
公开(公告)号：US08419656B2
公开(公告)日：2013-04-16
申请号：US11535092
申请日：2006-09-26
申请人： Steven E Field
发明人： Steven E Field
IPC分类号： A61B17/00
CPC分类号： A61B90/17 , A61B10/0041 , A61B10/0275 , A61B10/0283 , A61B90/39 , A61B2017/3488 , A61B2090/3908 , A61B2090/3987
摘要： An apparatus for implanting a locatable marker at a target site within a tissue mass comprises an insertion device and a marker introducer system that is received within the insertion device. The marker introducer system is anchored in a compressed tissue mass and a locatable marker is deployed from the introducer system after the tissue mass is decompressed.
摘要翻译：用于在组织块内的靶位置植入可定位标记的装置包括插入装置和标记导入器系统，其被插入到插入装置内。标记导引器系统锚定在压缩的组织块中，并且在组织块被减压之后从引导器系统展开定位标记。

38. 发明授权

US07862517B2 MRI biopsy device 有权
标题翻译： MRI活检装置
公开(公告)号：US07862517B2
公开(公告)日：2011-01-04
申请号：US11834034
申请日：2007-08-06
申请人： Mark Tsonton , Timothy G. Dietz , John A. Hibner , Jessica M. Pyzoha , Michael J. Andreyko , Keshava Datta , Michael A. Murray
发明人： Mark Tsonton , Timothy G. Dietz , John A. Hibner , Jessica M. Pyzoha , Michael J. Andreyko , Keshava Datta , Michael A. Murray
IPC分类号： A61B10/00
CPC分类号： A61B10/02 , A61B5/055 , A61B5/0555 , A61B10/0041 , A61B10/0233 , A61B10/0275 , A61B10/0283 , A61B17/3403 , A61B17/3417 , A61B17/3421 , A61B90/11 , A61B90/17 , A61B2010/0208 , A61B2010/0225 , A61B2017/00477 , A61B2017/00796 , A61B2017/00911 , A61B2017/3411 , A61B2090/034 , A61B2090/036 , A61B2090/374 , A61B2090/3908 , A61B2090/3933 , A61B2090/3954 , A61B2090/3987
摘要： A localization mechanism, or fixture, is used in conjunction with a breast coil for breast compression and for guiding a core biopsy instrument during prone biopsy procedures in both open and closed Magnetic Resonance Imaging (MRI) machines. The localization fixture includes a three-dimensional Cartesian positionable guide for supporting and orienting an MRI-compatible biopsy instrument, and in particular a sleeve, to a biopsy site of suspicious tissues or lesions. A depth stop enhances accurate insertion, and prevents over-insertion or inadvertent retraction of the sleeve. The sleeve receives a probe of the MRI-compatible biopsy instrument and may contain various features to enhance its imagability, to enhance vacuum and pressure assist therethrough, and marker deployment etc.
摘要翻译：定位机构或夹具与乳房线圈一起用于乳房压缩，并用于在开放和闭合的磁共振成像（MRI）机器中的易行活检过程中引导核心活检仪器。定位固定装置包括一个三维笛卡尔定位指南，用于支持和定向MRI兼容的活检仪器，特别是套筒，用于可疑组织或病变的活检部位。深度限位器可以提高精确的插入，并防止套筒的过度插入或无意的收回。袖子接受MRI兼容活检器械的探头，并且可以包含各种特征以增强其成像能力，以增强通过其中的真空和压力辅助以及标记部署等。

39. 发明申请

US20100160818A1 MRI Biopsy Device 审中-公开
标题翻译： MRI活检装置
公开(公告)号：US20100160818A1
公开(公告)日：2010-06-24
申请号：US12719173
申请日：2010-03-08
申请人： Wells D. Haberstich , Raj G. Raghavendran , John A. Hibner
发明人： Wells D. Haberstich , Raj G. Raghavendran , John A. Hibner
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B5/055 , A61B5/065 , A61B5/743 , A61B5/7435 , A61B10/0041 , A61B10/0266 , A61B10/0283 , A61B17/3403 , A61B90/11 , A61B90/17 , A61B90/36 , A61B2010/0208 , A61B2017/00128 , A61B2017/00199 , A61B2017/00212 , A61B2017/00796 , A61B2017/00911 , A61B2017/3411 , A61B2018/00928 , A61B2090/0811 , A61B2090/374 , A61B2090/3908 , A61B2090/3954 , A61B2090/3987 , A61B2560/0266 , A61B2560/0462
摘要： A magnetic resonance imaging (MRI) compatible core biopsy system uses a biopsy device having intuitive graphical displays and a detachable remote keypad that advantageously allows convenient control even within the close confines afforded by a localization fixture installed within a breast coil that localizes a patient's breast and guides a probe of the biopsy device relative to the localized breast. A control module for interactive control and power generation are remotely positioned and communicate and transmit rotational mechanical energy via sheathed cable.
摘要翻译：磁共振成像（MRI）兼容的核心活检系统使用具有直观的图形显示的活检装置和可拆卸的远程键盘，其有利地允许即使在由安装在乳房线圈内的定位夹具提供的紧密限制内的方便的控制下，使定位患者的乳房和引导活检装置相对于局部乳房的探针。用于交互控制和发电的控制模块被远程定位，并通过护套电缆传送和传输旋转机械能。

40. 发明授权

US07725170B2 Breast carcinoma detector 有权
标题翻译：乳腺癌检测器
公开(公告)号：US07725170B2
公开(公告)日：2010-05-25
申请号：US10471015
申请日：2002-03-13
申请人： Mitsuharu Miwa
发明人： Mitsuharu Miwa
IPC分类号： A61B6/00
CPC分类号： A61B5/4312 , A61B5/0091 , A61B10/0041
摘要： The breast cancer detector of the invention comprising a transparent breast pressing member 1 having a pressing face 4 which is pressed to a breast of a subject that makes it possible to observe the breast pressed to the body from the opposite face to the pressing face 4, a light source means 2 for irradiating light of a designated wavelength with respect to the breast in an area to which the pressing face 4 is pressed and an image pickup means 3 sensitive to light from the breast derived from irradiated light of the light source means 2 and obtaining the breast image through the breast pressing member 1, wherein breast cancer is detected from the breast image obtained by the image pickup means. Therefore, the breast is pressed to the body by using the breast pressing member 1 to keep the breast thin, thus making it possible to irradiate uniformly the light emitted from the light source 2 to an area of the breast to which the pressing face 4 is pressed. The light from the breast derived from the irradiated light is obtained from the image pickup means 3 to detect breast cancer in the breast from the thus-obtained image.
摘要翻译：本发明的乳腺癌检测器包括：透明乳房按压构件1，其具有按压面4，按压面4被按压到被检体的乳房，使得可以从与按压面4相反的面观察被按压到身体的乳房; 光源装置2，用于在按压面4的区域中照射相对于乳房的指定波长的光;以及摄像装置3，其对来自源自照射光的光源装置2的来自乳房的光敏感; 并且通过乳房按压部件1获得乳房图像，其中从由图像拾取装置获得的乳房图像中检测乳腺癌。因此，通过使用乳房按压部件1将乳房按压到身体，以保持乳房变薄，从而可以将从光源2发射的光均匀地照射到按压面4为乳房的区域按下。来自照射光的来自乳房的光从图像拾取装置3获得，以从如此获得的图像中检测乳房中的乳腺癌。

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