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31. 发明授权

US09427525B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09427525B2
公开(公告)日：2016-08-30
申请号：US13993526
申请日：2011-12-21
申请人： Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/20 , A61M5/2033 , A61M5/3202 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/208 , A61M2005/2086
摘要： The invention refers to an auto-injector comprising: a body, a syringe with a hollow injection needle and a stopper, wherein the syringe is slidably arranged with respect to the body, a torsion spring capable of, upon activation: pushing the needle from a covered position inside the body into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection, wherein the torsion spring is grounded at one end in the body and at the other end in a first gear member rotatable about a longitudinal axis, wherein the first gear member, upon rotation, is arranged for translating a second gear member toward the proximal end (P), the second gear member prevented from rotating and arranged to be coupled to the stopper in order to push it towards the proximal end (P), wherein the first gear member is engaged with the activating means prior to manual operation in a manner to prevent rotation and disengaged from the activating means upon manual operation, characterized in that a ratchet wheel is arranged on the first gear member, the ratchet wheel having a number of circumferentially arranged teeth, wherein the activating means comprise at least one locking feature for engaging the ratchet wheel in a manner to prevent rotation and wherein the locking feature is arranged to allow rotation on manual operation.
摘要翻译：本发明涉及一种自动注射器，包括：主体，具有中空注射针的注射器和塞子，其中所述注射器相对于所述主体可滑动地布置，能够在启动时将所述针从一个在主体内部的覆盖位置通过孔口并通过近端（P）进入先进位置，操作注射器以供应剂量的药物（M）;以及启动装置，其被布置成在手动之前将弹簧装置锁定在加压状态操作并且能够在手动操作时释放用于注射的弹簧装置，其中扭转弹簧在主体的一端接地，而另一端在可绕纵向轴线旋转的第一齿轮构件中接地，其中第一齿轮构件，在旋转时被布置成用于将第二齿轮构件朝向近端（P）平移，防止第二齿轮构件旋转并布置成联接到止动件，以将其推向p 近端（P），其中所述第一齿轮构件在手动操作之前与所述致动装置接合以防止在手动操作时旋转和从所述致动装置脱离的方式，其特征在于，棘轮设置在所述第一齿轮构件所述棘轮具有多个周向布置的齿，其中所述致动装置包括用于以防止旋转的方式接合所述棘轮的至少一个锁定特征，并且其中所述锁定特征被布置成允许手动操作旋转。

32. 发明授权

US09358351B2 Gearbox 有权
标题翻译：变速箱
公开(公告)号：US09358351B2
公开(公告)日：2016-06-07
申请号：US13580268
申请日：2011-02-16
申请人： Matthew Ekman , Thomas Mark Kemp , Timothy Donald Barrow-Williams
发明人： Matthew Ekman , Thomas Mark Kemp , Timothy Donald Barrow-Williams
IPC分类号： A61M5/46 , A61M5/145 , A61M5/20 , F16H25/12 , A61M5/32 , A61M5/315
CPC分类号： A61M5/46 , A61M5/1452 , A61M5/20 , A61M5/2033 , A61M5/3202 , A61M5/3257 , A61M5/326 , A61M2005/206 , A61M2005/208 , A61M2005/3152 , A61M2005/3247 , F16H25/12 , Y10T74/18656
摘要： The invention relates to a gearbox for converting a first translation into a second translation, the gearbox comprising a drive collar connectable to a translative drive means and prevented from rotating with respect to a ground of the drive means, a drive sleeve rotatably arranged at least partially inside the drive collar, engaged to the drive collar by a first screw thread and prevented from translating, wherein a plunger is arranged at least partially inside the drive sleeve, engaged to the drive sleeve by a second screw thread and prevented from rotating.
摘要翻译：本发明涉及一种用于将第一平移件转换成第二平移件的变速箱，所述变速箱包括可连接到平移驱动装置并被阻止相对于驱动装置的地面旋转的驱动轴环，驱动套筒可旋转地至少部分地布置在驱动套环内部，通过第一螺纹接合到驱动套环并防止其平移，其中柱塞至少部分地布置在驱动套筒的内部，通过第二螺纹与驱动套筒接合并防止其旋转。

33. 发明授权

US09242045B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09242045B2
公开(公告)日：2016-01-26
申请号：US13876168
申请日：2011-10-06
申请人： Rosie Burnell , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Rosie Burnell , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/2033 , A61M5/3202 , A61M2005/206 , A61M2005/2073
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising a housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, drive means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, and operating the syringe to supply the dose of medicament, and activating means arranged to lock the drive means in a loaded state prior to manual operation and capable of, upon manual operation, releasing the drive means for injection, characterized in that the drive means is at least one spring essentially transversally arranged with respect to a longitudinal axis of the syringe at least when in the loaded state.
摘要翻译：本发明涉及一种用于施用一剂液体药物的自动注射器，其包括被布置成容纳具有中空针的注射器的壳体和用于密封注射器并使药剂移位的塞子，该壳体具有远端和近端末端具有旨在施加到注射部位的孔口，其中所述注射器相对于所述壳体可滑动地布置，所述驱动装置能够在启动时将所述针头从所述壳体内的覆盖位置推入通过所述孔口的前进位置并且通过近端操作，并且操作注射器以供应剂量的药剂;以及激活装置，其布置成在手动操作之前将驱动装置锁定在加载状态，并且能够在手动操作时释放用于注射的驱动装置，其特征在于因为驱动装置至少是至少一个弹簧，至少基本上横向地相对于注射器的纵向轴线布置加载状态。

34. 发明授权

US09132242B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09132242B2
公开(公告)日：2015-09-15
申请号：US13994146
申请日：2011-12-21
申请人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20 , A61M5/315
CPC分类号： A61M5/2033 , A61M5/3202 , A61M5/3234 , A61M5/326 , A61M2005/206 , A61M2005/208 , A61M2005/31516 , A61M2005/3152 , A61M2005/3263
摘要： The invention refers to an auto-injector for administering a dose of a liquid medicament, comprising: an outer casing, a syringe with a hollow needle and a stopper a torsion spring and a gear arrangement for inserting the needle, delivering the medicament, and retracting the syringe after injection. At least one skin contact trigger element is arranged at a proximal end of the outer case, the skin contact trigger element translatable in longitudinal direction between a proximal position and a distal position and biased in proximal direction in a manner to protrude from the outer casing in the proximal position, wherein in its proximal position the skin contact trigger element is arranged to prevent the spring means from being released and wherein the skin contact trigger element in its distal position is arranged to allow release of the spring means.
摘要翻译：本发明涉及一种用于给药液体药物的自动注射器，其包括：外壳，具有中空针的注射器和止动器，扭转弹簧和用于插入针头，递送药物的齿轮装置和收缩注射器后注射。至少一个皮肤接触触发元件布置在外壳的近端处，皮肤接触触发元件可以在近端位置和远端位置之间的纵向方向上平移，并且在近端方向上以从外壳突出的方式偏置近端位置，其中在其近侧位置，皮肤接触触发元件布置成防止弹簧装置被释放，并且其中其远侧位置处的皮肤接触触发元件布置成允许释放弹簧装置。

35. 发明申请

US20130289525A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130289525A1
公开(公告)日：2013-10-31
申请号：US13996321
申请日：2011-12-21
申请人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32
CPC分类号： A61M5/3204 , A61M5/2033 , A61M5/31583 , A61M5/326 , A61M2005/206 , A61M2005/208
摘要： The invention refers to an auto-injector for administering a dose of a liquid medicament, comprising:an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the elongate housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing,spring means capable of, upon activation, pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and covering the needle on removal of the auto-injector from the injection site,activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection, characterized in that the spring means is a torsion spring, wherein a first gear arrangement and a second gear arrangement are arranged for respectively converting torque from a first end and a second end of the torsion spring into a translative force, wherein the first end is arranged to be groundable in the housing while the second end is configured to act on a plunger through the second gear arrangement for advancing the needle and supplying the dose, wherein the activating means is arranged to block or release the second gear arrangement and wherein the first end is releasable from the ground in the housing for causing a translation through the first gear arrangement resulting in the needle getting covered.
摘要翻译：本发明涉及一种用于施用一定剂量的液体药物的自动注射器，其包括：细长壳体，布置成容纳具有中空针头的注射器和用于密封注射器并移位药剂的塞子，细长壳体具有远端以及近端，其具有旨在施加在注射部位上的孔，其中所述注射器相对于所述壳体可滑动地布置，弹簧装置能够在启动时将所述针从所述壳体内的覆盖位置推入到前进位置通过孔口并通过近端，操作注射器以提供剂量的药物，并且在从注射部位移除自动注射器时覆盖针头，激活装置被布置成在手动之前将弹性装置锁定在加压状态操作并且能够在手动操作时释放用于注射的弹簧装置，其特征在于，弹簧装置是扭簧，其中第一齿轮装置和第二齿轮装置被布置成分别将来自扭转弹簧的第一端和第二端的扭矩转换成平移力，其中第一端被布置成在壳体中是可磨削的，而第二端构造通过第二齿轮装置作用在柱塞上，用于推进针头并提供剂量，其中激活装置被布置成阻挡或释放第二齿轮装置，并且其中第一端部可从壳体中的地面释放以引起翻转通过第一齿轮装置导致针被覆盖。

36. 发明申请

US20130204195A1 Force Transmission Arrangement for Auto-Injector 有权
标题翻译：自动进样器的力传动装置
公开(公告)号：US20130204195A1
公开(公告)日：2013-08-08
申请号：US13580146
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Thomas Mark Kemp
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Thomas Mark Kemp
IPC分类号： A61M5/315 , A61M5/20
CPC分类号： A61M5/3158 , A61M5/20 , A61M5/2033 , A61M5/315 , A61M5/3202 , A61M5/326 , A61M5/46 , A61M5/482 , A61M5/484 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2418 , A61M2005/3103 , A61M2005/3152 , A61M2005/3247 , A61M2205/581 , A61M2205/583
摘要： The invention relates to a transmission arrangement for controlling a force of a translation, the transmission arrangement comprising a drive collar (13) connectable to a translative drive means (11) and prevented from rotating with respect to a ground (12) of the drive means (11), a flange face of the drive collar (13) bearing against a mating flange face of a friction collar (20), the friction collar (20) slidable in longitudinal direction and rotationally constrained by engagement in a cam track (12.3), another flange face of the friction collar (20) bearing against a mating flange face of a plunger (8), the plunger (8) slidable in longitudinal direction and prevented from rotating.
摘要翻译：本发明涉及一种用于控制平移力的传动装置，该传动装置包括可连接到平移驱动装置（11）并被阻止相对于驱动装置（12）旋转的驱动套环（13）（11），所述驱动轴环（13）的凸缘面抵靠摩擦轴环（20）的配合凸缘面，所述摩擦轴环（20）可在纵向方向上滑动并通过接合在凸轮轨道（12.3）中而被旋转地限制，，所述摩擦轴环（20）的另一凸缘面抵靠着柱塞（8）的配合凸缘面，所述柱塞（8）可沿纵向方向滑动并防止旋转。

37. 发明申请

US20130281935A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130281935A1
公开(公告)日：2013-10-24
申请号：US13994146
申请日：2011-12-21
申请人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/2033 , A61M5/3202 , A61M5/3234 , A61M5/326 , A61M2005/206 , A61M2005/208 , A61M2005/31516 , A61M2005/3152 , A61M2005/3263
摘要： The invention refers to an auto-injector for administering a dose of a liquid medicament, comprising: an outer casing, a syringe with a hollow needle and a stopper a torsion spring and a gear arrangement for inserting the needle, delivering the medicament, and retracting the syringe after injection. At least one skin contact trigger element is arranged at a proximal end of the outer case, the skin contact trigger element translatable in longitudinal direction between a proximal position and a distal position and biased in proximal direction in a manner to protrude from the outer casing in the proximal position, wherein in its proximal position the skin contact trigger element is arranged to prevent the spring means from being released and wherein the skin contact trigger element in its distal position is arranged to allow release of the spring means.
摘要翻译：本发明涉及一种用于给药液体药物的自动注射器，其包括：外壳，具有中空针的注射器和止动器，扭转弹簧和用于插入针头，递送药物的齿轮装置和收缩注射器后注射。至少一个皮肤接触触发元件布置在外壳的近端处，皮肤接触触发元件可以在近端位置和远端位置之间的纵向方向上平移，并且在近端方向上以从外壳突出的方式偏置近端位置，其中在其近侧位置，皮肤接触触发元件布置成防止弹簧装置被释放，并且其中其远侧位置处的皮肤接触触发元件布置成允许释放弹簧装置。

38. 发明申请

US20130204198A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130204198A1
公开(公告)日：2013-08-08
申请号：US13876168
申请日：2011-10-06
申请人： Rosie Burnell , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Rosie Burnell , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/3202 , A61M2005/206 , A61M2005/2073
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising a housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, drive means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, and operating the syringe to supply the dose of medicament, and activating means arranged to lock the drive means in a loaded state prior to manual operation and capable of, upon manual operation, releasing the drive means for injection, characterized in that the drive means is at least one spring essentially transversally arranged with respect to a longitudinal axis of the syringe at least when in the loaded state.
摘要翻译：本发明涉及一种用于施用一剂液体药物的自动注射器，其包括被布置成容纳具有中空针的注射器的壳体和用于密封注射器并使药剂移位的塞子，该壳体具有远端和近端末端具有旨在施加到注射部位的孔口，其中所述注射器相对于所述壳体可滑动地布置，所述驱动装置能够在启动时将所述针头从所述壳体内的覆盖位置推入通过所述孔口的前进位置并且通过近端操作，并且操作注射器以供应剂量的药剂;以及激活装置，其布置成在手动操作之前将驱动装置锁定在加载状态，并且能够在手动操作时释放用于注射的驱动装置，其特征在于因为驱动装置至少是至少一个弹簧，至少基本上横向地相对于注射器的纵向轴线布置加载状态。

39. 发明申请

US20130131602A1 AUTO-INJECTOR WITH NEEDLE SHROUD AND NEEDLE PROTECTION CAP 有权
标题翻译：自动注射器，带针头和针头保护帽
公开(公告)号：US20130131602A1
公开(公告)日：2013-05-23
申请号：US13580271
申请日：2011-02-16
申请人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/3202 , A61M5/2033 , A61M5/315 , A61M5/326 , A61M5/46 , A61M5/482 , A61M5/484 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2418 , A61M2005/3103 , A61M2005/3152 , A61M2005/3247 , A61M2205/581 , A61M2205/583 , F16H25/20 , F16H25/2056
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament (M). A shroud is arranged at least partially inside a housing, the shroud slidable in longitudinal direction between at least a retracted position, in which a hollow injection needle is exposable and an advanced position, in which the needle is covered by the shroud, wherein the shroud is arranged to be locked in the retracted position prior to manual operation of an activation means and wherein the shroud is arranged to be pushed towards the advanced position by a syringe spring when a drive means has been released by the activation means. A protective needle shield is attachable to the needle in a manner to partially protrude beyond the proximal end of the shroud through the orifice with the needle in its advanced position, wherein a syringe carrier is arranged inside the shroud for holding a syringe, the syringe carrier slidable with respect to the shroud, wherein the syringe carrier comprises at least one resilient snap for locking it to the shroud in order to prevent relative axial motion, wherein the snap is arranged to be supportable from inside by the protective needle shield when attached to the needle in order to remain engaged with the shroud and wherein the snap is inwardly biased to disengage from the shroud without support from inside in a manner to automatically disengage upon removal of the protective needle shield thus allowing the syringe and needle to be retracted into the covered position under load of the syringe spring.
摘要翻译：本发明涉及一种用于施用剂量的液体药物（M）的自动注射器。护罩至少部分地布置在壳体内部，护罩可在至少缩回位置（其中空心注射针可暴露于其中）和前进位置之间在纵向方向上滑动，在该位置中针被护罩覆盖，其中护罩被布置成在手动操作激活装置之前被锁定在缩回位置，并且其中所述护罩布置成当驱动装置已经被激活装置释放时被注射器弹簧推向前进位置。保护针护罩可以以针部分突出超过护罩的近端的方式穿过针头，其中针处于其前进位置，其中注射器托架布置在护罩内用于保持注射器，注射器托架可相对于护罩滑动，其中注射器托架包括至少一个弹性卡扣，用于将其锁定到护罩上以防止相对的轴向运动，其中卡扣被布置成当附接到护罩时由保护针护罩从内部支撑针，以便保持与护罩接合，并且其中卡扣被向内偏置以从内部脱离，而不需要内部的支撑，以便在移除保护针护罩时自动脱开，从而允许注射器和针头缩回到被覆盖注射器弹簧的负载位置。

40. 发明申请

US20130131595A1 GEARBOX 有权
标题翻译：齿轮箱
公开(公告)号：US20130131595A1
公开(公告)日：2013-05-23
申请号：US13580268
申请日：2011-02-16
申请人： Matthew Ekman , Thomas Mark Kemp , Timothy Donald Barrow-Williams
发明人： Matthew Ekman , Thomas Mark Kemp , Timothy Donald Barrow-Williams
IPC分类号： A61M5/46 , A61M5/20 , A61M5/32 , F16H25/12
CPC分类号： A61M5/46 , A61M5/1452 , A61M5/20 , A61M5/2033 , A61M5/3202 , A61M5/3257 , A61M5/326 , A61M2005/206 , A61M2005/208 , A61M2005/3152 , A61M2005/3247 , F16H25/12 , Y10T74/18656
摘要： The invention relates to a gearbox for converting a first translation into a second translation, the gearbox comprising a drive collar connectable to a translative drive means and prevented from rotating with respect to a ground of the drive means, a drive sleeve rotatably arranged at least partially inside the drive collar, engaged to the drive collar by a first screw thread and prevented from translating, wherein a plunger is arranged at least partially inside the drive sleeve, engaged to the drive sleeve by a second screw thread and prevented from rotating.
摘要翻译：本发明涉及一种用于将第一平移件转换成第二平移件的变速箱，所述变速箱包括可连接到平移驱动装置并被阻止相对于驱动装置的地面旋转的驱动轴环，驱动套筒可旋转地至少部分地布置在驱动套环内部，通过第一螺纹接合到驱动套环并防止其平移，其中柱塞至少部分地布置在驱动套筒的内部，通过第二螺纹与驱动套筒接合并防止其旋转。

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