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31. 发明申请

US20070010786A1 Catheter 审中-公开
标题翻译：导管
公开(公告)号：US20070010786A1
公开(公告)日：2007-01-11
申请号：US11311927
申请日：2005-12-19
申请人： Brendan Casey , Avril O'Higgins , Eamon Brady , Patrick Griffin
发明人： Brendan Casey , Avril O'Higgins , Eamon Brady , Patrick Griffin
IPC分类号： A61M31/00
CPC分类号： A61M25/0068 , A61B17/22031 , A61B17/3439 , A61F2002/011 , A61M25/0043 , A61M25/0052 , A61M25/0074 , A61M25/008 , A61M25/0082 , A61M2025/0081
摘要： A catheter 1 suitable for advancement through a body passageway of a patient. The catheter 1 comprises a catheter body 4 which is flexible to provide the necessary trackability for the catheter 1 to advance through a body passageway, and two stainless steel reinforcement wires 5 extending along the catheter body 4 which provide the necessary pushability to advance the catheter 1 through the passageway. The reinforcements 5 are positioned diametrically opposed to one another by approximately 180 degrees on opposite sides of the longitudinal axis of the catheter 1, and the catheter body 4 is relatively soft and twistable. This configuration enables the entire catheter 1 to spontaneously twist during advancement so that the reinforcements 5 orientate themselves along a plane of neutral bending during advancement of the catheter 1. In this way, any resistance to the trackability of the catheter 1 due to the stiff reinforcements 5 is minimised.
摘要翻译：适于通过患者的身体通道前进的导管1。导管1包括导管主体4，该导管主体4是灵活的，以便为导管1提供穿过身体通道提供必要的可追踪性，以及沿着导管主体4延伸的两根不锈钢加强线5，它们提供推进导管1 通过通道。加强件5在导管1的纵向轴线的相对侧上彼此径向相对地设置大约180度，并且导管主体4相对较软和可扭转。这种构造使得整个导管1能够在推进期间自发扭曲，使得加强件5在导管1的前进过程中沿着中性弯曲平面定向。以这种方式，由于刚性增强件导致的导管1的可追踪性的任何阻力 5被最小化。

32. 发明申请

US20060287669A1 Catheter 审中-公开
标题翻译：导管
公开(公告)号：US20060287669A1
公开(公告)日：2006-12-21
申请号：US11314152
申请日：2005-12-21
申请人： Brendan Casey , Avril O'Higgins , Eamon Brady , Patrick Griffin , Michael Gilvarry
发明人： Brendan Casey , Avril O'Higgins , Eamon Brady , Patrick Griffin , Michael Gilvarry
IPC分类号： A61M29/00
CPC分类号： A61M25/0068 , A61B17/22031 , A61B17/3439 , A61F2002/011 , A61M25/0043 , A61M25/0052 , A61M25/0074 , A61M25/008 , A61M25/0082 , A61M2025/0081
摘要： A retrieval catheter having a retrieval catheter tip 1 at a distal end thereof, the tip being suitable for retrieving an embolic protection filter into the tip 1. The tip 1 comprises a flexible tip body 2 and two stiff reinforcement columns 3. The tip body 2 is radially expandable to facilitate retrieval of a filter into the tip 1, and the columns 3 extend longitudinally along the tip body 2 to prevent buckling of the tip 1 upon retrieval of the filter into the tip. The cross-sectional area of the columns 3, the cross sectional area of the tip body 2, and the overall cross-sectional area of the tip 1 all remain substantially unchanged along the length of the tip 1. This ensures the reinforcement provided to the tip 1 by the columns 3 remains substantially uniform along the length of the tip 1. Thus no longitudinal squeezing of the filter as it is retrieved into the tip 1 will be caused.
摘要翻译：一种取出导管，其在其远端具有取回导管尖端1，所述尖端适于将栓塞保护过滤器收回到尖端1中。尖端1包括柔性末端主体2和两个刚性加强柱3。尖端体2是可径向扩张的，以便于将过滤器取出到尖端1中，并且柱3沿着尖端体2纵向延伸，以防止在将过滤器收回到尖端中时尖端1的弯曲。柱3的横截面面积，末端体2的横截面面积和尖端1的总横截面面积全部沿尖端1的长度基本保持不变。这确保了通过柱3提供给尖端1的加强沿着尖端1的长度保持基本均匀。因此，当过滤器被回收到尖端1中时，不会纵向挤压过滤器。

33. 发明申请

US20060247676A1 Retrieval device 审中-公开
标题翻译：检索装置
公开(公告)号：US20060247676A1
公开(公告)日：2006-11-02
申请号：US11475069
申请日：2006-06-27
申请人： David Vale , Paul Gilson , Patrick Griffin
发明人： David Vale , Paul Gilson , Patrick Griffin
IPC分类号： A61M29/00
CPC分类号： A61B17/22031 , A61F2/013 , A61F2002/011 , A61F2002/9528 , A61F2230/0006 , A61M25/104 , A61M2025/1093
摘要： A retrieval device (1) for retrieval of an embolic filter (2) from the vasculature (3) comprises a guide catheter (42), a retrieval catheter (10) and a centring catheter (11) which is threaded over a guidewire (25). The retrieval catheter (10) comprises an elongate flexible tube (15) including a radially expansible distal tip (19) with an open mouth (40) for retrieval of the embolic filter (2). The centring catheter (11) also comprises an elongate tube (20) which extends through the retrieval catheter tube (15) and terminates in a distal tapered end (21). The centring catheter (1) is used to centre the retrieval catheter (10) in the vasculature (3) to enable the retrieval catheter (10) to freely pass through a stenosis and/or stent to retrieve the filter (2). When the retrieval catheter (10) is in position the centring catheter (11) is withdrawn through the retrieval catheter (10).
摘要翻译：用于从脉管系统（3）检索栓塞过滤器（2）的检索装置（1）包括引导导管（42），取出导管（10）和定心导管（11），所述引导导管（10）和定心导管（11）穿过导丝）。取回导管（10）包括细长的柔性管（15），其包括具有用于抽吸栓塞过滤器（2）的开口（40）的可径向扩张的远端尖端（19）。定心导管（11）还包括延伸穿过取出导管（15）并终止于远端锥形端（21）的细长管（20）。定心导管（1）用于将取出导管（10）置于脉管系统（3）中，以使回收导管（10）自由通过狭窄和/或支架以取回过滤器（2）。当取回导管（10）就位时，定中心导管（11）通过取出导管（10）取出。

34. 发明申请

US20050156013A1 Method of making high performance heat sinks 失效
标题翻译：制造高性能散热片的方法
公开(公告)号：US20050156013A1
公开(公告)日：2005-07-21
申请号：US11033334
申请日：2005-01-11
申请人： Mohinder Bhatti , Patrick Griffin
发明人： Mohinder Bhatti , Patrick Griffin
IPC分类号： B23K1/00 , F28F3/02 , H01L21/48 , H01L23/367
CPC分类号： F28F3/025 , B23P2700/10 , F28D2021/0029 , H01L21/4882 , H01L23/3672 , H01L2924/0002 , Y10T156/10 , H01L2924/00
摘要： A method of heat sink manufacture in which the crests of a conductive fin are nested down into close fitting grooves in a flat, conductive base plate, with small interface gaps G. A compressive material is set inside the fin crests and the grooves, viscous enough to not intrude into the gaps G, to a level sufficient to substantially fill the grooves. The work piece thus created is subjected to a cold hydrostatic oil bath, crushing the outer surfaces of the fin crests into the internal surfaces of the grooves where the compressed seal covers, while the rest of the fin is supported against net deformation by the surrounding oil.
摘要翻译：一种散热器制造方法，其中导电翅片的顶部嵌入到具有小的界面间隙G的平坦导电基板中的紧密配合的凹槽中。压缩材料设置在翅片顶部和沟槽内，足够粘稠以不将间隙G侵入到足以基本上填充凹槽的水平。将如此制成的工件进行冷静液压油浴，将翅片顶部的外表面破碎成压缩密封件覆盖的凹槽的内表面，而其余的翅片由周围的油支撑而变形。

35. 发明授权

US08241319B2 Embolic protection system 有权
标题翻译：栓塞保护系统
公开(公告)号：US08241319B2
公开(公告)日：2012-08-14
申请号：US11841302
申请日：2007-08-20
申请人： Paul Gilson , Charles Taylor , Patrick Griffin , John Nielan , David Vale , Eamon Brady
发明人： Paul Gilson , Charles Taylor , Patrick Griffin , John Nielan , David Vale , Eamon Brady
IPC分类号： A61M29/00
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection system 1 comprises a guidewire 99 for advancing through a vasculature, the guidewire 99 having a distal end and a proximal end; an embolic protection filter 1 having a filter body 41 with a distal end and a proximal end, the filter body 41 providing for a collapsed configuration and an expanded deployed configuration. The embolic protection filter body 41 has a guidewire path for slidably receiving the guidewire 99 to permit movement of the filter 1 relative to the guidewire 99 when the filter 1 is in the collapsed configuration and the expanded deployed configuration. A delivery catheter 2 is advanceable over the guidewire 99 for delivery of the embolic protection filter 1; the delivery catheter 2 having a proximal end and a distal end. The filter 1 is deployed from the distal end of the delivery catheter 2 into the expanded deployed configuration. A retrieval catheter 3 is also advanceable over the guidewire 99 for retrieval of the filter 1, the retrieval catheter 3 having a distal end and a proximal end; and engagement elements for engaging the embolic protection filter 1 with the guidewire 99 for retrieval of the filter 1 into the retrieval catheter 3 in the collapsed configuration.
摘要翻译：栓塞保护系统1包括用于前进通过脉管系统的导丝99，导丝99具有远端和近端; 一种栓塞保护过滤器1，其具有带有远端和近端的过滤器本体41，过滤体41提供收缩构型和展开的展开构型。栓塞保护过滤器主体41具有用于可滑动地接收导丝99的导丝路径，以允许过滤器1相对于导丝99移动，当过滤器1处于折叠构型和展开展开构型时。输送导管2可以在引导线99上前进，用于输送栓塞保护过滤器1; 输送导管2具有近端和远端。过滤器1从输送导管2的远端部署到展开的部署构型中。取出导管3也可以在引导线99上前进，用于取出过滤器1，回收导管3具有远端和近端; 以及用于使栓塞保护过滤器1与导线99接合以用于以折叠构型将过滤器1回收到回收导管3中的接合元件。

36. 发明授权

US07846176B2 Embolic protection system 有权
公开(公告)号：US07846176B2
公开(公告)日：2010-12-07
申请号：US11669460
申请日：2007-01-31
申请人： Paul Gilson , Charles Taylor , Patrick Griffin , Michael Gilvarry , David Vale , Eamon Brady
发明人： Paul Gilson , Charles Taylor , Patrick Griffin , Michael Gilvarry , David Vale , Eamon Brady
IPC分类号： A61M29/00
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： An assembly for loading a collapsible embolic protection filter 1 into a catheter 2, comprises a catheter 2 defining a reception space at a distal end of the catheter 2 for receiving a collapsed embolic protection filter 1; and a separate removable pushing device 8 for delivering the embolic protection filter 1 into the reception space. The pushing device 8 comprises an elongate stem 71 with a proximal stop 72 for engagement with the filter 1. A separate loading device 7 to collapse the embolic protection filter 1 is also provided. The loading device 7 defines an inlet end and an outlet end, the outlet end being configured for co-operative alignment with the reception space.

37. 发明申请

US20080262506A1 CATHETER 审中-公开
标题翻译：导管
公开(公告)号：US20080262506A1
公开(公告)日：2008-10-23
申请号：US11841259
申请日：2007-08-20
申请人： Patrick Griffin , Brendan Casey , Avril O'Higgins , Michael Gilvarry , Siora Coll
发明人： Patrick Griffin , Brendan Casey , Avril O'Higgins , Michael Gilvarry , Siora Coll
IPC分类号： A61M25/00
CPC分类号： A61F2/013 , A61F2/95 , A61F2002/011 , A61F2002/9528 , A61F2230/0006
摘要： A retrieval catheter 1 for retrieval of an embolic protection filter from a vasculature. The catheter 1 comprises a proximal hypotube 3, a radially offset distal shaft 4 and a centering shank 9. A guidewire lumen 13 is provided through the shank 9 in communication with a larger guidewire lumen 7 through the shaft 4 for a continuous guidewire passageway to accommodate passage of a guidewire 21 through the shank 9, the shaft 4 and out through a proximal guidewire opening 6 to facilitate rapid exchange of the catheter 1 over a guidewire 21. The shank 9 is movable between an introduction configuration in which the shank 9 protrudes distally from the shaft 4 to centre the catheter 1 during advancement through a vasculature, and a retrieval configuration in which the shank 9 is located within the guidewire lumen 7 to facilitate retrieval of an embolic protection filter into the shaft 4.
摘要翻译：一种用于从脉管系统检索栓塞保护过滤器的检索导管1。导管1包括近端海波管3，径向偏移的远端轴4和定心柄9。导丝管腔13设置成穿过柄部9，通过轴4与较大的导丝管腔7连通，用于连续的导丝通道，以适应导丝21通过柄9，轴4的通过，并通过近端导丝开口6 以促进导管1在导丝21上的快速交换。柄9可以在引导构型之间移动，在引入构型中，柄9从轴4向远端突出，以便在通过脉管系统推进期间使导管1居中;以及取出构型，其中柄9位于导丝管腔7内以便于取出的栓塞保护过滤器进入轴4。

38. 发明申请

US20070282369A1 EMBOLIC PROTECTION DEVICE 审中-公开
标题翻译：嵌入式保护装置
公开(公告)号：US20070282369A1
公开(公告)日：2007-12-06
申请号：US11691130
申请日：2007-03-26
申请人： Paul Gilson , Charles Taylor , Patrick Griffin , John Nielan , David Vale , Eamon Brady
发明人： Paul Gilson , Charles Taylor , Patrick Griffin , John Nielan , David Vale , Eamon Brady
IPC分类号： A61F2/01
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection system 1 comprises a guidewire 99 for advancing through a vasculature, the guidewire 99 having a distal end and a proximal end; an embolic protection filter 1 having a filter body 41 with a distal end and a proximal end, the filter body 41 providing for a collapsed configuration and an expanded deployed configuration. The embolic protection filter body 41 has a guidewire path for slidably receiving the guidewire 99 to permit movement of the filter 1 relative to the guidewire 99 when the filter 1 is in the collapsed configuration and the expanded deployed configuration. A delivery catheter 2 is advanceable over the guidewire 99 for delivery of the embolic protection filter 1; the delivery catheter 2 having a proximal end and a distal end. The filter 1 is deployed from the distal end of the delivery catheter 2 into the expanded deployed configuration. A retrieval catheter 3 is also advanceable over the guidewire 99 for retrieval of the filter 1, the retrieval catheter 3 having a distal end and a proximal end; and engagement elements for engaging the embolic protection filter 1 with the guidewire 99 for retrieval of the filter 1 into the retrieval catheter 3 in the collapsed configuration.
摘要翻译：栓塞保护系统1包括用于前进通过脉管系统的导丝99，导丝99具有远端和近端; 一种栓塞保护过滤器1，其具有带有远端和近端的过滤器本体41，过滤体41提供收缩构型和展开的展开构型。栓塞保护过滤器主体41具有用于可滑动地接收导丝99的导丝路径，以允许过滤器1相对于导丝99移动，当过滤器1处于折叠构型和展开展开构型时。输送导管2可以在引导线99上前进，用于输送栓塞保护过滤器1; 输送导管2具有近端和远端。过滤器1从输送导管2的远端部署到展开的部署构型中。取出导管3也可以在引导线99上前进，用于取出过滤器1，回收导管3具有远端和近端; 以及用于使栓塞保护过滤器1与导线99接合以用于以折叠构型将过滤器1回收到回收导管3中的接合元件。

39. 发明申请

US20070208372A1 EMBOLIC PROTECTION SYSTEM 有权
公开(公告)号：US20070208372A1
公开(公告)日：2007-09-06
申请号：US11669447
申请日：2007-01-31
申请人： Paul GILSON , Charles Taylor , Patrick Griffin , Michael Gilvarry , David Vale , Eamon Brady
发明人： Paul GILSON , Charles Taylor , Patrick Griffin , Michael Gilvarry , David Vale , Eamon Brady
IPC分类号： A61F2/06 , A61B17/00
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： An assembly for loading a collapsible embolic protection filter 1 into a catheter 2, comprises a catheter 2 defining a reception space at a distal end of the catheter 2 for receiving a collapsed embolic protection filter 1; and a separate removable pushing device 8 for delivering the embolic protection filter 1 into the reception space. The pushing device 8 comprises an elongate stem 71 with a proximal stop 72 for engagement with the filter 1. A separate loading device 7 to collapse the embolic protection filter 1 is also provided. The loading device 7 defines an inlet end and an outlet end, the outlet end being configured for co-operative alignment with the reception space.

40. 发明申请

US20070005101A1 Filter catheter 审中-公开
标题翻译：过滤导管
公开(公告)号：US20070005101A1
公开(公告)日：2007-01-04
申请号：US11406819
申请日：2006-04-18
申请人： Gary Fahey , Ronald Kelly , Patrick Griffin , Eamon Brady
发明人： Gary Fahey , Ronald Kelly , Patrick Griffin , Eamon Brady
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2230/0006 , A61M2025/0059 , A61M2025/0183
摘要： A filter retrieval catheter for retrieving an embolic protection filter (50) from a vasculature. The catheter comprises a catheter shaft (2) having a rapid exchange guidewire opening (4) in a sidewall of the catheter shaft (2) to facilitate rapid exchange of the catheter over a guidewire (5). To prevent buckling or kinking of the catheter shaft (2) in the region of the guidewire opening (4) during retrieval of the embolic protection filer (50), the catheter comprises two elongate reinforcement elements (6, 3) extending along the catheter shaft (2). The first reinforcement element (6) comprises an elongate wire element extending from a proximal end located proximally of the guidewire opening (4) to a distal end located distally of the guidewire opening (4). The second reinforcement element (3) comprises an elongate tubular element extending from a proximal end located adjacent to and distally of the guidewire opening (4) to a distal end (9) located further distally of the guidewire opening (4). The tube (3) tapers distally radially outwardly adjacent to the distal end (9). This tapered part (9) of the tube (3) is fixedly attached to the interior surface of the catheter shaft (2).
摘要翻译：一种用于从脉管系统检索栓塞保护过滤器（50）的过滤器取回导管。导管包括在导管轴（2）的侧壁中具有快速交换导丝开口（4）的导管轴（2），以便于在导线（5）上快速更换导管。为了防止导管轴（2）在引导线开口（4）的区域中在栓塞保护滤波器（50）的取回期间的屈曲或扭结，导管包括沿着导管轴延伸的两个细长的加强元件（6,3）（2）。第一增强元件（6）包括从位于导丝开口（4）的近侧的近端延伸到位于导丝开口（4）的远侧的远端的细长线元件。第二加强元件（3）包括细长管状元件，其从邻近导丝开口（4）的远端的近端延伸到远离导丝开口（4）的远端（9）。管（3）沿与远端（9）相邻的径向向外径向逐渐变细。管（3）的该锥形部分（9）固定地附接到导管轴（2）的内表面。

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