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    • 37. 发明申请
    • PREPARATIONS WITH IMPROVED PHYSICAL PROPERTIES
    • 具有改进的物理性质的制备
    • US20150250693A1
    • 2015-09-10
    • US14638367
    • 2015-03-04
    • SYMRISE AG
    • Anja FinkeSabine LangeGerhard Schmaus
    • A61K8/37A61Q5/02A61K8/06A61Q19/10
    • A61K8/37A61K8/062A61K8/34A61K2800/52A61Q5/02A61Q19/10B01F17/0021
    • A preparation is described comprising one or more alcohols of the formula (I), wherein in each case one of the two moieties Ra or Rb represents hydrogen and the other moiety Ra or Rb in each case represents a straight-chain or branched acyl moiety having 2 to 10 carbon atoms, and one or more further compounds, wherein the preparation is an O/W emulsion, the particle size distribution for which the following applies: D(v, 0.9)=40 μm or less, wherein in the preparation the total quantity of the alcohol(s) of the formula (I) is selected in such a way that the O/W emulsion, compared to a comparison emulsion which having an otherwise identical composition does not comprise any alcohol of the formula (I), has an increased emulsion stability, and/or wherein the preparation is a surfactant-containing preparation and the total quantity of the alcohol(s) of the formula (I) in the preparation is selected in such a way that the preparation, compared to a comparison preparation which having an otherwise identical composition does nor comprise any alcohol of the formula (I), has an increased viscosity at 22.7° C.
    • 描述了包含一种或多种式(I)的醇的制剂,其中在每种情况下,两个部分Ra或Rb中的一个表示氢,而另一个部分Ra或Rb在每种情况下表示具有直链或支链酰基部分, 2至10个碳原子,和一种或多种其它化合物,其中制剂是O / W乳液,其适用的粒径分布:D(v,0.9)=40μm或更小,其中在制备中 选择式(I)的醇的总量,使得O / W乳液与具有相同组成的比较乳液相比不包含任何式(I)的任何醇, 具有增加的乳液稳定性,和/或其中制剂是含表面活性剂的制剂,并且选择制剂中式(I)的醇的总量,使得制剂与 比较准备 相同的组成不含或不包含式(I)的任何醇,在22.7℃具有增加的粘度