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31. 发明申请

US20060258694A1 HISTONE DEACETYLASE INHIBITORS 失效
标题翻译： HISTONE脱乙酰酶抑制剂
公开(公告)号：US20060258694A1
公开(公告)日：2006-11-16
申请号：US11382659
申请日：2006-05-10
申请人： Jerome Bressi , Jason Brown , Anthony Gangloff , Jeffrey Stafford , Phong Vu
发明人： Jerome Bressi , Jason Brown , Anthony Gangloff , Jeffrey Stafford , Phong Vu
IPC分类号： A61K31/513 , C07D403/02
CPC分类号： C07D513/04 , C07D239/80 , C07D285/24 , C07D417/04 , C07D417/06 , C07D417/12
摘要： Compounds, pharmaceutical compositions, kits and methods are provided for use with HDAC that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要翻译：提供化合物，药物组合物，试剂盒和方法用于HDAC，其包含选自以下的化合物：其中变量如本文所定义。

32. 发明申请

US20050153966A1 Kinase inhibitors 失效
标题翻译：激酶抑制剂
公开(公告)号：US20050153966A1
公开(公告)日：2005-07-14
申请号：US11015348
申请日：2004-12-17
申请人： Anthony Gangloff , Jacek Nowakowski , Bheema Paraselli , Jeffrey Stafford , Michael Tennant
发明人： Anthony Gangloff , Jacek Nowakowski , Bheema Paraselli , Jeffrey Stafford , Michael Tennant
IPC分类号： A61K31/519 , A61K31/53 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D471/04 , C07D487/02 , C07D513/04
CPC分类号： C07D409/14 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D471/04 , C07D513/04
摘要： The invention relates to compounds of the following formula that may be used to inhibits kinases, as well as compositions of matter and kits comprising these compounds. The present invention also relates to methods for inhibiting kinases, as well as treatment methods using compounds according to the present invention.
摘要翻译：本发明涉及可用于抑制激酶的下式的化合物，以及包含这些化合物的物质组合物和试剂盒。本发明还涉及抑制激酶的方法，以及使用根据本发明的化合物的治疗方法。

33. 发明申请

US20100257551A1 DYNAMIC VIDEO CONTENT 审中-公开
标题翻译：动态视频内容
公开(公告)号：US20100257551A1
公开(公告)日：2010-10-07
申请号：US12416270
申请日：2009-04-01
申请人： Jeffrey Sweeney , Kelsyn D.S Rooks , Jeffrey Stafford
发明人： Jeffrey Sweeney , Kelsyn D.S Rooks , Jeffrey Stafford
IPC分类号： H04N7/025 , H04N7/173
CPC分类号： H04N7/165 , H04N21/23424 , H04N21/2343 , H04N21/812 , H04N21/845
摘要： Embodiments of the disclosed invention include a system and method for providing customized video content to a viewer. For example, in one embodiment, the method includes analyzing a video file for identifying a geometric shape associated with a replaceable item within the video file. The method selects from a database a second item corresponding to the geometric shape of the replaceable item based on information associated with a user profile of the viewer. The method overlays a respective viewable portion of the second item on top of a respective viewable portion of the replaceable item within the video file to generate a new video file. The method transmits the new video file to the viewer.
摘要翻译：所公开的发明的实施例包括用于向观看者提供定制的视频内容的系统和方法。例如，在一个实施例中，该方法包括分析用于识别与视频文件内的可替换项目相关联的几何形状的视频文件。该方法基于与观众的用户简档相关联的信息，从数据库中选择与可替换项目的几何形状相对应的第二项目。所述方法将所述第二项目的相应可见部分覆盖在所述视频文件内的所述可替换项目的相应可见部分之上，以生成新的视频文件。该方法将新的视频文件发送给观看者。

34. 发明申请

US20070142437A1 CHEMICAL COMPOUNDS 审中-公开
标题翻译：化学化合物
公开(公告)号：US20070142437A1
公开(公告)日：2007-06-21
申请号：US11670498
申请日：2007-02-02
申请人： Matthew Brown , Mui Cheung , Scott Dickerson , Cassandra Gauthier , Philip Harris , Robert Hunter , Gregory Pacofsky , Michael Peel , Jeffrey Stafford
发明人： Matthew Brown , Mui Cheung , Scott Dickerson , Cassandra Gauthier , Philip Harris , Robert Hunter , Gregory Pacofsky , Michael Peel , Jeffrey Stafford
IPC分类号： A61K31/4439 , A61K31/427 , A61K31/423 , C07D413/02 , C07D417/02
CPC分类号： C07D263/48 , C07D413/04 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/10 , C07D417/12 , C07D417/14
摘要： Oxazole derivatives, which are useful as VEGFR2, CDK2, and CDK4 inhibitors are described herein. The described invention also includes methods of making such oxazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译：本文描述了可用作VEGFR2，CDK2和CDK4抑制剂的恶唑衍生物。所述的发明还包括制备这种恶唑衍生物的方法以及使用它们在治疗过度增殖性疾病中的方法。

35. 发明申请

US20070135420A1 Short-acting benzodiazepines 有权
标题翻译：短效苯二氮卓类
公开(公告)号：US20070135420A1
公开(公告)日：2007-06-14
申请号：US11650636
申请日：2007-01-05
申请人： Paul Feldman , David Jung , Istvan Kaldor , Gregory Pacofsky , Jeffrey Stafford , Jeffrey Tidwell
发明人： Paul Feldman , David Jung , Istvan Kaldor , Gregory Pacofsky , Jeffrey Stafford , Jeffrey Tidwell
IPC分类号： A61K31/5513 , C07D403/02 , C07D243/14
CPC分类号： C07D243/20 , C07D401/04 , C07D401/12 , C07D403/12 , C07D487/04
摘要： It has now been found that compounds of the present invention as described in Benzodiazepine derivatives of Formula (I) containing a carboxylic ester moiety and thereby capable of being inactivated by nonspecific tissue esterases in an organ-independent elimination mechanism and thereby providing a more predictable and reproducible pharmacodynamic profile. The compounds of the present invention are suitable for therapeutic purposes, including sedative-hypnotic, anxiolytic, muscle relaxant and anticonvulsant purposes and are useful to be administered intravenously in the following clinical settings: preoperative sedation, anxiolysis, and amnestic use for perioperative events; conscious sedation during short diagnostic, operative or endoscopic procedures; as a component for the induction and maintenance of general anesthesia, prior and/or concomitant to the administration of other anesthetic agents; ICU sedation.
摘要翻译：现已发现如在含有羧酸酯部分的式（I）的苯并二氮杂衍生物中所描述的本发明化合物，由此能够在器官非依赖性消除机制中被非特异性组织酯酶灭活，从而提供更可预测和可重现的药效学特征。本发明的化合物适用于治疗目的，包括镇静催眠，抗焦虑药，肌肉松弛剂和抗惊厥药物，并可用于在以下临床环境中静脉内施用：术前镇静，抗焦虑和围手术期的遗忘用途; 短期诊断，手术或内窥镜手术中有意义的镇静; 作为全身麻醉的诱导和维持的组成部分，先前和/或伴随其他麻醉剂的施用; ICU镇静。

36. 发明申请

US20050015940A1 Anchoring clamp 审中-公开
标题翻译：锚固夹
公开(公告)号：US20050015940A1
公开(公告)日：2005-01-27
申请号：US10612492
申请日：2003-07-02
申请人： Jeffrey Stafford
发明人： Jeffrey Stafford
IPC分类号： B64F1/16 , F16G11/00 , F16G11/06
CPC分类号： B64F1/16 , F16G11/06 , F16G11/143 , Y10T24/3958 , Y10T24/3967
摘要： A clamp assembly for securing a flexible cable comprising an elongated body portion, a bore extending through the body portion, a clamping screw mounted in a sidewall of the body portion mounting a shoe at its inner end which snugly fits in a pocket, said shoe having an arcuate face to snugly embrace the cable and a means to finding a recess in the bore wall located opposite said show whereby rotation of screw in direction to advance the shoe inwardly presses the cable into the recess to firmly lock it in place.
摘要翻译：一种用于固定柔性电缆的夹具组件，包括细长主体部分，延伸通过主体部分的孔，安装在主体部分的侧壁中的夹紧螺钉，其安装在其内端处的鞋底，该内部端部紧密配合在口袋中，所述鞋具有弧形表面以紧密地包围电缆，并且在位于所述示意图相对位置的孔壁中找到凹槽的装置，由此螺钉在推进鞋的方向上的旋转将电缆进入凹部以将其牢固地锁定在适当的位置。

37. 发明授权

US08571532B2 System and method for providing cellular call gating via a femto cell 有权
标题翻译：通过毫微微小区提供蜂窝呼叫门控的系统和方法
公开(公告)号：US08571532B2
公开(公告)日：2013-10-29
申请号：US12403060
申请日：2009-03-12
申请人： Jeffrey Sweeney , Kelsyn D. S. Rooks , Jeffrey Stafford
发明人： Jeffrey Sweeney , Kelsyn D. S. Rooks , Jeffrey Stafford
IPC分类号： H04M3/42
CPC分类号： H04M1/663 , H04M1/66 , H04M3/42161 , H04M3/436 , H04M2207/18 , H04W4/16
摘要： Embodiments of the disclosed invention include a system and method for providing cellular call gating. For example, in one embodiment, a femto cell is disclosed that includes a transceiver configured to send and receive signals associated with a registered cellular device; a processing unit configured to execute instructions to enable call gating function associated with the registered cellular device; a network interface configured to receive an incoming call to the registered cellular device; a caller identification module configured to identifying a caller ID associated with the incoming call; a data storage unit containing a list of allowed caller IDs associated with the registered cellular device; and a call gating module configured to route the incoming call to the registered cellular device if the caller ID associated with the incoming call is on the list of allowed caller IDs.
摘要翻译：所公开的发明的实施例包括用于提供蜂窝呼叫门控的系统和方法。例如，在一个实施例中，公开了一种毫微微小区，其包括被配置为发送和接收与注册的蜂窝设备相关联的信号的收发器; 处理单元，被配置为执行指令以启用与所注册的蜂窝设备相关联的呼叫门控功能; 网络接口，被配置为接收到所登记的蜂窝设备的呼入; 呼叫者识别模块，被配置为识别与所述呼入呼叫相关联的呼叫者ID; 数据存储单元，其包含与所注册的蜂窝设备相关联的允许呼叫者ID的列表; 以及呼叫门控模块，其被配置为如果与所述来电相关联的呼叫者ID在所允许的呼叫者ID的列表上，则将所述呼入路由到所述注册的蜂窝设备。

38. 发明申请

US20070135419A1 Short-acting benzodiazepines 有权
公开(公告)号：US20070135419A1
公开(公告)日：2007-06-14
申请号：US11650635
申请日：2007-01-05
申请人： Paul Feldman , David Jung , Istvan Kaldor , Gregory Pacofsky , Jeffrey Stafford , Jeffrey Tidwell
发明人： Paul Feldman , David Jung , Istvan Kaldor , Gregory Pacofsky , Jeffrey Stafford , Jeffrey Tidwell
IPC分类号： A61K31/5513 , C07D243/14
CPC分类号： C07D243/20 , C07D401/04 , C07D401/12 , C07D403/12 , C07D487/04
摘要： The present invention provides a compound of formula (I): wherein all variables are as defined herein, pharmaceutical formulations containing the same, processes for preparing the same and their use therapy.

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