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31. 发明申请

US20160158405A1 LIPOSOMAL DRUG DELIVERY SYSTEM FOR BONE CEMENTS 有权
标题翻译：用于骨骼化学物质的药物输送系统
公开(公告)号：US20160158405A1
公开(公告)日：2016-06-09
申请号：US14903803
申请日：2014-07-09
申请人： Stephen DENYER , Samuel EVANS , Wayne AYRE , UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED
发明人： Stephen Denyer , Samuel Evans , Wayne Ayre
IPC分类号： A61L24/00 , A61K31/7036 , A61L24/04 , A61K9/127
CPC分类号： A61L24/0015 , A61K9/1271 , A61K31/7036 , A61L24/0094 , A61L24/046 , A61L27/54 , A61L2300/23 , A61L2300/406 , A61L2300/626 , A61L2430/02 , C08L33/12
摘要： The invention relates to a novel antibiotic delivery vehicle for impregnating bone cement wherein said vehicle is an antibiotic encapsulated liposome having a block co-polymer on its surface; a method for the manufacture of a bone cement impregnated with antibiotic or a mixture of antibiotics using said vehicle; and also a novel bone cement made therewith and/or thereby.
摘要翻译：本发明涉及一种用于浸渍骨水泥的新型抗生素递送载体，其中所述载体是其表面上具有嵌段共聚物的抗生素包封的脂质体; 使用所述载体制造浸渍有抗生素或抗生素混合物的骨水泥的方法; 以及由此制成的新型骨水泥和/或由此制成的骨水泥。

32. 发明申请

US20070088108A1 Stabilization of polyolefins with liquid cyclic phosphites 审中-公开
标题翻译：用液体环状亚磷酸酯稳定聚烯烃
公开(公告)号：US20070088108A1
公开(公告)日：2007-04-19
申请号：US11545844
申请日：2006-10-11
申请人： Samuel Evans , Sai Shum , Roswell King , Walid Al-Akhdar
发明人： Samuel Evans , Sai Shum , Roswell King , Walid Al-Akhdar
IPC分类号： C08K5/5399 , C09K15/32
CPC分类号： C07F9/65742 , C08K5/527 , C09K15/322 , C08L23/02
摘要： The present invention discloses liquid cyclic phosphites of for example the formula where n is 1 or 2; when n is 1, R17 is straight or branched chain alkyl of 1 to 18 carbon atoms, when n is 2, R17 is —CtH2t— or —CH2CH2-T3-CH2CH2— where T3 is —S— or >N—R22 where R22 is straight or branched chain alkyl of 1 to 12 carbon atoms and t is an integer of from 2 to 6, R1, R2, R3, R4, R5 and R6 are independently hydrogen, methyl, ethyl, i-propyl, n-propyl, n-butyl, sec-butyl or t-butyl and R is hydrogen. Also disclosed is a stabilized composition comprising polyolefin and a present liquid cyclic phosphite and a process for the stabilization of polyolefin by incorporating therein or applying thereto a present liquid cyclic phosphite. The present liquid phosphite stabilizers are especially compatible with polyolefins.
摘要翻译：本发明公开了例如其中n为1或2的式的液体环状亚磷酸酯; 当n为1时，R 17为具有1至18个碳原子的直链或支链烷基，当n为2时，R 17为-C≡C- 2 H 2 - 或-CH 2 CH 2 - - - - 3 CH 2 - 其中T 3为-S-或> NR 22，其中R 22为直链或 - 1至12个碳原子的支链烷基，t为2至6的整数，R 1，R 2，R 3， R 4，R 5和R 6独立地是氢，甲基，乙基，异丙基，正丙基，正丁基，仲丁基丁基或叔丁基，R为氢。还公开了包含聚烯烃和本发明的液体环状亚磷酸酯的稳定化组合物，以及通过在其中引入或施加本发明的液体环状亚磷酸酯来稳定聚烯烃的方法。本发明的液体亚磷酸酯稳定剂与聚烯烃特别相容。

33. 发明授权

US07160955B2 Sulfoxides or sulfones grafted onto polymers 失效
标题翻译：接枝到聚合物上的亚砜或砜
公开(公告)号：US07160955B2
公开(公告)日：2007-01-09
申请号：US10473848
申请日：2002-03-26
申请人： Hans-Rudolf Meier , Gerrit Knobloch , Pierre Rota-Graziosi , Samuel Evans , Paul Dubs , Michèle Gerster
发明人： Hans-Rudolf Meier , Gerrit Knobloch , Pierre Rota-Graziosi , Samuel Evans , Paul Dubs , Michèle Gerster
IPC分类号： C08F8/34
CPC分类号： C07D303/22 , C07C317/04 , C07C317/10 , C07C317/18 , C07C317/44 , C07C323/12 , C07C323/25 , C07C323/52 , C07C323/65 , C07C2601/14 , C07D303/16 , C07D405/12 , C07F7/1804 , C08C19/20 , C08C19/22 , C08K5/36
摘要： Polymers grafted with a compound of formula I, formula (I) wherein the general symbols are as defined in claim 1, have outstanding stability against oxidative, thermal, dynamic, light-induced and/or ozone-induced degradation [R1—SOmnR—SOp—R2. (I)
摘要翻译：用式I化合物（I）接枝的聚合物，其中通式如权利要求1所定义，具有优异的抗氧化，热，动态，光诱导和/或臭氧诱导的降解的稳定性，公式描述=“在线公式”end =“lead”？> [R＆lt; 1＆lt;＆lt;＆lt;＆lt;＆gt;＆lt; img id =“PRIVATE-USE-CHARACTER-00001” =“6.77mm”wi =“8.47mm”file =“US07160955-20070109-Brketclosest.TIF”alt =“私人使用字符Brketclosest”img-content =“character”img-format =“tif”/> R 2 SO 2 -R 2。（I）<？in-line-formula description =“In-line Formulas”end =“tail”？>

34. 发明授权

US06407231B1 Process for the preparation of a mixture of alkylated phenothiazines and diphenylamines 失效
标题翻译：制备烷基化吩噻嗪和二苯胺的混合物的方法
公开(公告)号：US06407231B1
公开(公告)日：2002-06-18
申请号：US09609960
申请日：2000-07-05
申请人： Samuel Evans , Stephan Allenbach , Paul Dubs
发明人： Samuel Evans , Stephan Allenbach , Paul Dubs
IPC分类号： C07D27918
CPC分类号： C07D279/36 , C07C209/68 , C07D279/20 , C07C211/55
摘要： This invention relates to a novel, technically advantageous process for the preparation of a mixture of alkylated phenothiazines and diphenylamines. Starting from diphenylamine, this is reacted with elemental sulfur in the presence of iodine, and the substance mixture of diphenylamine and phenothiazine is treated with an olefin in the presence of an acid catalyst.
摘要翻译：本发明涉及一种制备烷基化吩噻嗪和二苯胺的混合物的技术上有利的方法。从二苯胺开始，在碘的存在下，与元素硫反应，在酸催化剂存在下用烯烃处理二苯胺与吩噻嗪的物质混合物。

35. 发明授权

US06362138B1 Heterocyclic thioethers as additives for lubricants 失效
标题翻译：杂环硫醚作为润滑剂的添加剂
公开(公告)号：US06362138B1
公开(公告)日：2002-03-26
申请号：US09663822
申请日：2000-09-15
申请人： Hugo Camenzind , Samuel Evans , Alfred Dratva , Peter Hänggi
发明人： Hugo Camenzind , Samuel Evans , Alfred Dratva , Peter Hänggi
IPC分类号： C10M13536
CPC分类号： C07D285/08 , C07D277/74 , C10L1/2456 , C10L10/04 , C10L10/08 , C10M135/36 , C10M2219/10 , C10M2219/102 , C10M2219/104 , C10M2219/106 , C10N2240/08 , C10N2240/40 , C10N2270/02
摘要： This invention relates to compounds which are suitable as ash-free antiwear additives and antioxidants, to lubricant compositions comprising said compounds as well as to their use. are particularly preferred. In the preferred compounds I′, R2 is isooctyloxycarbonylmethyl, R3 is isooctyloxycarbonylmethylthiomethyl and R4 is hydrogen; or R2 is tert-nonyl and R3 is tert-nonylthiomethyl and R4 is hydrogen; or R2 is isooctyloxycarbonylmethyl, R3 is hydrogen and R4 is isooctyloxycarbonylmethylthiomethyl; or R2 is tert-nonyl, R3 is hydrogen and R4 I is tert-nonylthiomethyl. In the preferred compounds II′, R2 and R2′ are isooctyloxycarbonylmethyl, R3 and R3′ are isooctyloxycarbonylmethylthiomethyl and R4 and R4′ are hydrogen; or R2 and R2′ are tert-nonyl, R3 and R3′ are tert-nonylthiomethyl and R4 and R4′ are hydrogen; or R2 and R2′ are isooctyloxycarbonylmethyl, R3 and R3′ are hydrogen and R4 and R4′ are isooctyloxycarbonylmethylthio; or R2 and R2′ are tert-nonyl, R3 and R3′ are hydrogen and R4 and R4′ are tert-nonylthiomethyl.
摘要翻译：本发明涉及适合作为无灰抗磨添加剂和抗氧化剂的化合物，包含所述化合物的润滑剂组合物及其用途，特别优选。在优选的化合物I'中，R 2为异辛氧基羰基甲基，R 3为异辛氧基羰基甲硫基甲基和R4 是氢; 或R 2为叔壬基，R 3为叔壬硫基甲基，R 4为氢; 或R 2为异辛氧基羰基甲基，R 3为氢，R 4为异辛氧基羰基甲硫基甲基; 或R 2是叔丁基，R 3是氢，R 4是叔壬基硫基甲基。在优选的化合物II'中，R 2和R 2'是异辛氧基羰基甲基，R 3和R 3'是异辛氧基羰基甲硫基甲基，R 4和R 4'是氢; 或R 2和R 2'是叔壬基，R 3和R 3'是叔壬硫基甲基，R 4和R 4'是氢; 或R2和R2'是异辛氧基羰基甲基，R3和R3'是氢，R4和R4'是异辛氧基羰基甲硫基; 或R 2和R 2'是叔壬基，R 3和R 3'是氢，R 4和R 4'是叔壬基硫基甲基。

36. 发明授权

US06359148B1 3-arylbenzofuranones as stabilizers 失效
标题翻译： 3-芳基苯并呋喃酮作为稳定剂
公开(公告)号：US06359148B1
公开(公告)日：2002-03-19
申请号：US09121583
申请日：1998-07-23
申请人： Peter Nesvadba , Samuel Evans , Christoph Kröhnke , Jürg Zingg
发明人： Peter Nesvadba , Samuel Evans , Christoph Kröhnke , Jürg Zingg
IPC分类号： C07D40904
CPC分类号： C07D307/91 , C07D307/83 , C07D405/04 , C08K5/1535 , C08K5/17 , C08K5/20 , C08K5/372 , C08K5/45 , C10M129/20 , C10M129/24 , C10M129/68 , C10M133/44 , C10M135/32 , C10M2207/044 , C10M2207/046 , C10M2207/28 , C10M2215/22 , C10M2215/221 , C10M2215/224 , C10M2215/225 , C10M2215/226 , C10M2215/30 , C10M2219/10 , C10M2219/102 , C10M2219/104 , C10M2219/106 , C10N2240/08 , C10N2240/10 , C10N2240/101 , C10N2240/104 , C10N2240/106 , C10N2240/40 , C08L23/02
摘要： The invention described novel compounds of formula wherein the general symbols are as defined in claim 1, as stabilisers for protecting organic materials, in particular polymers and lubricants, against thermal, oxidative or light-induced degradation.
摘要翻译：本发明描述了通式符号如权利要求1中所定义的新型化合物，作为用于保护有机材料，特别是聚合物和润滑剂的稳定剂，防止热，氧化或光诱导的降解。

37. 发明授权

US06150307A Heterocyclic thioethers as additives for lubricants 失效
标题翻译：杂环硫醚作为润滑剂的添加剂
公开(公告)号：US06150307A
公开(公告)日：2000-11-21
申请号：US128086
申请日：1998-08-03
申请人： Hugo Camenzind , Samuel Evans , Alfred Dratva , Peter Hanggi
发明人： Hugo Camenzind , Samuel Evans , Alfred Dratva , Peter Hanggi
IPC分类号： C07D277/70 , C07D277/74 , C07D285/08 , C07D285/125 , C10L1/24 , C10L10/04 , C10M105/70 , C10M105/72 , C10M135/36 , C10N30/10
CPC分类号： C07D285/08 , C07D277/74 , C10L1/2456 , C10L10/04 , C10L10/08 , C10M135/36 , C10M2219/10 , C10M2219/102 , C10M2219/104 , C10M2219/106 , C10N2240/08 , C10N2240/40 , C10N2270/02
摘要： This invention relates to compounds which are suitable as ash-free antiwear additives and antioxidants, to lubricant compositions comprising said compounds as well as to their use. Compounds of formulae ##STR1## are particularly preferred. In the preferred compounds I',R.sub.2 is isooctyloxycarbonylmethyl, R.sub.3 is isooctyloxycarbonylmethylthiomethyl and R.sub.4 is hydrogen; orR.sub.2 is tert-nonyl and R.sub.3 is tert-nonylthiomethyl and R.sub.4 is hydrogen; orR.sub.2 is isooctyloxycarbonylmethyl, R.sub.3 is hydrogen and R.sub.4 is isooctyloxycarbonylmethylthiomethyl; orR.sub.2 is tert-nonyl, R.sub.3 is hydrogen and R.sub.4 I is tert-nonylthiomethyl.In the preferred compounds II',R.sub.2 and R.sub.2 ' are isooctyloxycarbonylmethyl, R.sub.3 and R.sub.3 ' are isooctyloxycarbonylmethylthiomethyl and R.sub.4 and R.sub.4 ' are hydrogen; orR.sub.2 and R.sub.2 ' are tert-nonyl, R.sub.3 and R.sub.3 ' are tert-nonylthiomethyl and R.sub.4 and R.sub.4 ' are hydrogen; orR.sub.2 and R.sub.2 ' are isooctyloxycarbonylmethyl, R.sub.3 and R.sub.3 ' are hydrogen and R.sub.4 and R.sub.4 ' are isooctyloxycarbonylmethylthio; orR.sub.2 and R.sub.2 ' are tert-nonyl, R.sub.3 and R.sub.3 ' are hydrogen and R.sub.4 and R.sub.4 ' are tert-nonylthiomethyl.
摘要翻译：本发明涉及适合作为无灰抗磨添加剂和抗氧化剂的化合物，包括所述化合物的润滑剂组合物及其用途。式的化合物是特别优选的。在优选的化合物I'中，R 2为异辛氧基羰基甲基，R 3为异辛氧基羰基甲硫基甲基，R4为氢; 或R 2为叔壬基，R 3为叔壬基硫基甲基，R 4为氢; 或R2是异辛氧基羰基甲基，R3是氢，R4是异辛氧基羰基甲硫基甲基; 或R 2为叔壬基，R 3为氢，R 4'为叔壬基硫基甲基。在优选的化合物II'中，R2和R2'是异辛氧基羰基甲基，R3和R3'是异辛氧基羰基甲硫基甲基，R4和R4'是氢; 或R 2和R 2'为叔壬基，R 3和R 3'为叔壬硫基甲基，R 4和R 4'为氢; 或R 2和R 2'为异辛氧基羰基甲基，R 3和R 3'为氢，且R 4和R 4'为异辛氧基羰基甲硫基; 或R 2和R 2'为叔壬基，R 3和R 3'为氢，且R 4和R 4'为叔壬基硫基甲基。

38. 发明授权

US5696281A Liquid phenolic antioxidants 失效
标题翻译：液体酚类抗氧化剂
公开(公告)号：US5696281A
公开(公告)日：1997-12-09
申请号：US454362
申请日：1995-06-20
申请人： Samuel Evans
发明人： Samuel Evans
IPC分类号： C07C67/03 , C07C67/08 , C07C67/14 , C07C69/732 , C08K5/10 , C08K5/101 , C08K5/134 , C09K15/08 , C10M129/66 , C10N30/10 , C07C69/76
CPC分类号： C07C69/732 , C08K5/134
摘要： The present invention relates to novel liquid phenolic antioxidants, to organic materials stabilized with said compounds against thermal, oxidalive and/or actinic degradation, and to the use of said novel compounds as stabilizers.
摘要翻译： PCT No.PCT / EP93 / 03502 Sec。 371日期：1995年6月20日 102（e）1995年6月20日PCT 1993年12月10日PCT PCT。第WO94 / 14748号公报日本时间1994年7月7日本发明涉及新型液体酚类抗氧化剂，所述有机物质用所述化合物稳定化，防止热，氧化和/或光化降解，以及使用所述新化合物作为稳定剂。

39. 发明授权

US5672574A Stabilizers for organic materials 失效
标题翻译：有机材料稳定剂
公开(公告)号：US5672574A
公开(公告)日：1997-09-30
申请号：US530974
申请日：1995-09-20
申请人： Samuel Evans , Stephan Allenbach
发明人： Samuel Evans , Stephan Allenbach
IPC分类号： C07C39/21 , C07C39/225 , C07C43/23 , C07C69/14 , C07C69/22 , C07C323/18 , C08K5/00 , C08K5/04 , C09K15/08 , C09K15/14 , C09K15/24 , C10M169/04 , D06M13/02 , D06M13/144 , D06M13/152 , D06M13/224 , D06M13/248 , D06M13/252 , D06M101/00 , D06M101/16 , D06M101/18 , C10M129/10 , C10M129/16
CPC分类号： C08K5/005
摘要： Compositions comprising compounds of formula ##STR1## wherein the radicals R and R.sub.1 to R.sub.5 are as defined in claim 1, are described. Some of those compounds are novel. They are suitable for the stabilization of organic materials.
摘要翻译：描述了包含式（I）的化合物的组合物，其中基团R和R 1至R 5如权利要求1中所定义。这些化合物中的一些是新的。它们适用于有机材料的稳定化。

40. 发明授权

US5614572A Benzofuran-2-ones as stabilizers 失效
标题翻译：苯并呋喃-2-酮作为稳定剂
公开(公告)号：US5614572A
公开(公告)日：1997-03-25
申请号：US304470
申请日：1994-09-12
申请人： Peter Nesvadba , Samuel Evans
发明人： Peter Nesvadba , Samuel Evans
IPC分类号： C07D307/88 , C07D307/83 , C08K5/15 , C08K5/1535 , C09K15/06 , C09K15/20 , C09K15/28
CPC分类号： C08K5/1535 , C07D307/83
摘要： The invention relates to compounds of formula I ##STR1## wherein the general symbols are as defined in claim 1, as stabilisers for protecting organic materials against thermal, oxidative or light-induced degradation.
摘要翻译：本发明涉及式I化合物，其中通式如权利要求1所定义，作为保护有机材料免受热，氧化或光诱导降解的稳定剂。

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