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31. 发明授权

US08124382B2 Methods, microarray, and kits for detection of drug resistance genes in gram-negative bacteria 有权
标题翻译：用于检测革兰氏阴性菌耐药基因的方法，微阵列和试剂盒
公开(公告)号：US08124382B2
公开(公告)日：2012-02-28
申请号：US12097237
申请日：2007-01-18
申请人： Lingxiang Zhu , Zhiwei Zhang , Di Jiang , Ning Du , Can Wang , Huawei Yang , Qiong Zhang , Huafang Gao , Yuxiang Zhou , Jing Cheng
发明人： Lingxiang Zhu , Zhiwei Zhang , Di Jiang , Ning Du , Can Wang , Huawei Yang , Qiong Zhang , Huafang Gao , Yuxiang Zhou , Jing Cheng
IPC分类号： C12P19/34
CPC分类号： C12Q1/689 , C12Q2600/156 , C12Q2600/16 , C12Q2600/166
摘要： The present invention provides kits and microarrays containing primer pairs for amplifying drug resistance genes and/or probes for detection of drug resistance genes. Also provided are methods of detecting drug resistance genes using kits and microarrays described herein.
摘要翻译：本发明提供了包含用于扩增用于检测药物抗性基因的药物抗性基因和/或探针的引物对的试剂盒和微阵列。还提供了使用本文所述的试剂盒和微阵列检测药物抗性基因的方法。

32. 发明申请

US20110264511A1 ONLINE SERVING THRESHOLD AND DELIVERY POLICY ADJUSTMENT 有权
标题翻译：在线服务门槛和交付政策调整
公开(公告)号：US20110264511A1
公开(公告)日：2011-10-27
申请号：US12764732
申请日：2010-04-21
申请人： Qiong Zhang
发明人： Qiong Zhang
IPC分类号： G06Q30/00 , G06Q10/00 , G06F15/18
CPC分类号： G06Q30/02 , G06Q30/0242 , G06Q30/0244
摘要： The present invention provides techniques for use in association with online advertising, relating to use of serving thresholds, associated with predicted click through rates, and delivery policies, associated with advertising inventory serving and distribution. An offline-trained machine learning-based model may be utilized in advertising serving decision-making in connection with serving opportunities. However, serving thresholds and delivery policies, for use in association with the model in serving decision-making, may be adjusted online, such as in real-time or near real-time, based on information obtained online affecting factors such as predicted click through rates and advertising inventory distribution.
摘要翻译：本发明提供了与在线广告相关联的技术，涉及与广告库存服务和分发相关联的与预测的点击率和递送策略相关联的服务阈值的使用。基于离线训练的机器学习型模型可以用于与服务机会相关的广告服务决策。然而，根据在线获取的信息，可以在线调整用于与服务决策中的模型配合的服务阈值和交付政策，例如实时或接近实时的影响因素，如预测的点击率价格和广告库存分配。

33. 发明申请

US20110243030A1 SYSTEMS AND METHODS FOR DETERMINING PROTECTION PATHS IN A MULTI-DOMAIN NETWORK 有权
标题翻译：用于确定多域网络中的保护程序的系统和方法
公开(公告)号：US20110243030A1
公开(公告)日：2011-10-06
申请号：US12751599
申请日：2010-03-31
申请人： Qiong Zhang , Mohammad Masud Hasan , Xi Wang , Paparao Palacharla , Takao Naito , Fredrick S. Gruman
发明人： Qiong Zhang , Mohammad Masud Hasan , Xi Wang , Paparao Palacharla , Takao Naito , Fredrick S. Gruman
IPC分类号： H04L12/28
CPC分类号： H04L45/04 , H04L45/128 , H04L45/22 , H04L45/24 , H04L45/28
摘要： Systems and methods for determining multiple paths in a multi-domain network are provided. In some embodiment, a method for determining multiple paths in a network is provided. The method may include determining a first path between a source node and a destination node and determining a second path disjoint from the first path. In some embodiments, to determine the second path includes determining which ingress nodes are available in a domain that includes the destination node, where the available ingress nodes are not part of the first path, and implementing a disjoint path algorithm for each of the available ingress nodes. To determine the first path includes implementing forward path calculations.
摘要翻译：提供了用于确定多域网络中的多个路径的系统和方法。在一些实施例中，提供了一种用于确定网络中的多个路径的方法。该方法可以包括确定源节点和目的地节点之间的第一路径并确定与第一路径不相交的第二路径。在一些实施例中，为了确定第二路径包括确定哪些入口节点在包括目的地节点的域中是可用的，其中可用入口节点不是第一路径的一部分，并且为每个可用入口实现不相交路径算法节点。确定第一条路径包括实现前向路径计算。

34. 发明申请

US20110208708A1 Systems and Methods for Finding Keyword Relationships Using Wisdoms from Multiple Sources 有权
标题翻译：使用多个来源的智慧查找关键词关系的系统和方法
公开(公告)号：US20110208708A1
公开(公告)日：2011-08-25
申请号：US12712800
申请日：2010-02-25
申请人： Weiguo Liu , Qiong Zhang
发明人： Weiguo Liu , Qiong Zhang
IPC分类号： G06F17/30
CPC分类号： G06F17/3064 , G06Q30/0241
摘要： Systems and methods for finding related terms based on three different sources are disclosed. Generally, a first plurality of distances is determined based on one or more received terms and a first plurality of terms derived from an algorithmic search list. A second plurality of distances is determined based on the one or more received terms and a second plurality of terms derived from a sponsored search list. A third plurality of distances is determined based on the one or more received terms and a third plurality of terms derived from search logs. The first, second, and third pluralities of distances are combined to derive a fourth plurality of distances. Finally, a plurality of related terms related to the one or more received terms is generated based on the fourth plurality of distances.
摘要翻译：公开了基于三种不同来源查找相关术语的系统和方法。通常，基于从算法搜索列表导出的一个或多个接收到的项和第一多个项来确定第一多个距离。基于从赞助的搜索列表导出的一个或多个接收到的项和第二多个项来确定第二多个距离。基于从搜索日志导出的一个或多个接收到的项和第三多个项来确定第三多个距离。将第一，第二和第三多个距离组合以得出第四多个距离。最后，基于第四多个距离生成与一个或多个所接收的项相关的多个相关项。

35. 发明申请

US20110167183A1 Minimizing Interconnections In A Multi-Shelf Switching System 有权
标题翻译：最小化多层交换系统中的互连
公开(公告)号：US20110167183A1
公开(公告)日：2011-07-07
申请号：US12683504
申请日：2010-01-07
申请人： Qiong Zhang , Paparao Palacharla , Xi Wang , Takao Naito
发明人： Qiong Zhang , Paparao Palacharla , Xi Wang , Takao Naito
IPC分类号： G06F13/14 , G06F13/00
CPC分类号： H04L47/10 , H04L41/12
摘要： In certain embodiments, minimizing interconnections in a multi-shelf switching system includes receiving a map describing the switching system, where the switching system comprises shelves and input/output (I/O) points. The map is transformed to yield a graph comprising nodes and edges. A node represents an I/O point, and a node weight represents a number of interface cards of the I/O point represented by the node. An edge between a node pair represents traffic demand between the I/O points represented by the node pair, and an edge weight represents the amount of the traffic demand represented by the edge. The graph is partitioned to yield a groups that minimize interconnection traffic among the shelves, where each group represents a shelf of the multi-shelf switching system.
摘要翻译：在某些实施例中，最小化多货架交换系统中的互连包括接收描述交换系统的映射，其中交换系统包括货架和输入/输出（I / O）点。该图被变换以产生包括节点和边的图。节点表示I / O点，节点权重表示由节点表示的I / O点的接口卡数量。节点对之间的边缘表示由节点对表示的I / O点之间的业务需求，边缘权重表示由边缘表示的业务量需求量。该图被分割以产生使架之间的互连流量最小化的组，其中每个组表示多货架交换系统的货架。

36. 发明申请

US20100003246A1 Novel heterocyclic compounds and uses therof 失效
标题翻译：新型杂环化合物并使用
公开(公告)号：US20100003246A1
公开(公告)日：2010-01-07
申请号：US12383035
申请日：2009-03-19
申请人： Zilin Hunag , Jeff Jin , Timothy Machajewski , William R. Antonios-McCrea , Maureen McKenna , Daniel Poon , Paul A. Renhowe , Martin Sendzik , Cynthia Shafer , Aaron Smith , Yongjin Xu , Qiong Zhang , Zheng Chen
发明人： Zilin Hunag , Jeff Jin , Timothy Machajewski , William R. Antonios-McCrea , Maureen McKenna , Daniel Poon , Paul A. Renhowe , Martin Sendzik , Cynthia Shafer , Aaron Smith , Yongjin Xu , Qiong Zhang , Zheng Chen
IPC分类号： A61K31/444 , C07D401/14 , C07D403/14 , C07D471/04 , A61K31/506 , A61K31/437 , A61P35/00 , A61K31/4545 , A61K31/7068 , A61K31/505 , A61K33/24 , A61K39/395
CPC分类号： C07D498/04 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04
摘要： New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
摘要翻译：提供了新的取代的杂环化合物，含有它们的组合物，以及使用它们来抑制Raf激酶活性的方法。新化合物和组合物可以单独使用或与至少一种另外的药物组合使用，用于治疗Raf激酶介导的病症，例如癌症。

37. 发明授权

US09580437B2 Triazolopyrimidine compounds and uses thereof 有权
标题翻译：三唑并嘧啶化合物及其用途
公开(公告)号：US09580437B2
公开(公告)日：2017-02-28
申请号：US14977273
申请日：2015-12-21
申请人： Ho Man Chan , Xiang-Ju Justin Gu , Ying Huang , Ling Li , Yuan Mi , Wei Qi , Martin Sendzik , Yongfeng Sun , Long Wang , Zhengtian Yu , Hailong Zhang , Ji Yue (Jeff) Zhang , Man Zhang , Qiong Zhang , Kehao Zhao
发明人： Ho Man Chan , Xiang-Ju Justin Gu , Ying Huang , Ling Li , Yuan Mi , Wei Qi , Martin Sendzik , Yongfeng Sun , Long Wang , Zhengtian Yu , Hailong Zhang , Ji Yue (Jeff) Zhang , Man Zhang , Qiong Zhang , Kehao Zhao
IPC分类号： C07D487/04 , A61K31/519 , A61K31/541 , A61K31/551 , A61K45/06 , A61K31/5377
CPC分类号： A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K45/06 , C07D487/04
摘要： A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.
摘要翻译：提供式（I）化合物或其药学上可接受的盐，其已被证明可用于治疗PRC2介导的疾病或病症：其中R1，R2，R3，R4，R5和n如所定义这里。

38. 发明授权

US09154858B2 Probability-based regenerator site analysis 有权
标题翻译：基于概率的再生器现场分析
公开(公告)号：US09154858B2
公开(公告)日：2015-10-06
申请号：US13585663
申请日：2012-08-14
申请人： Xi Wang , Qiong Zhang , Paparao Palacharla , Motoyoshi Sekiya
发明人： Xi Wang , Qiong Zhang , Paparao Palacharla , Motoyoshi Sekiya
IPC分类号： G06G7/48 , H04Q11/00 , H04J14/00 , H04L12/24
CPC分类号： H04Q11/00 , H04J14/00 , H04L41/142 , H04L41/145 , H04Q2213/13164 , H04Q2213/13335
摘要： An optical network analysis tool includes a computer-readable storage medium having computer-readable instructions stored thereon. The computer-readable instructions are executable by a computing device to perform operations. The operations include generating a simulated network that models an optical network. The simulated network includes regenerator candidate sites. The operations may also include conducting an analysis of the optical network. The analysis includes introducing a multiple signals transmitted between source/destination pairs and recording a number of times each of the regenerator candidate sites are selected as a regenerator site while applying each of a set of data traffic conditions in the simulated network. The operations may also include statistically analyzing the number of times each of the regenerator candidate sites is selected to generate statistically analyzed information and presenting the statistically analyzed information.
摘要翻译：光网络分析工具包括其上存储有计算机可读指令的计算机可读存储介质。计算机可读指令可由计算设备执行以执行操作。这些操作包括生成模拟光网络的模拟网络。模拟网络包括再生器候选站点。这些操作还可以包括进行光网络的分析。该分析包括引入在源/目的地对之间传输的多个信号，并且在将模拟网络中的一组数据业务条件应用中的每一个的同时，将每个再生器候选站点选择为多个次数作为再生站站点进行记录。操作还可以包括统计分析每个再生器候选位点被选择以产生统计分析的信息并呈现统计分析的信息的次数。

39. 发明授权

US09014559B2 Methods for efficient transmission in OTN networks 有权
标题翻译： OTN网络中高效传输的方法
公开(公告)号：US09014559B2
公开(公告)日：2015-04-21
申请号：US13116710
申请日：2011-05-26
申请人： Qiong Zhang , Paparao Palacharla , Motoyoshi Sekiya
发明人： Qiong Zhang , Paparao Palacharla , Motoyoshi Sekiya
IPC分类号： G02F1/00 , G02F2/00 , H01S3/00 , H04B10/00 , H04J14/00 , H04J3/16 , H04J3/14
CPC分类号： H04J3/1652 , H04J3/14
摘要： In accordance with some embodiments of the present disclosure a method for shared mesh protection in an optical transport network comprises provisioning a route for each of a plurality of working demands through the optical transport network. The method further comprises provisioning a route for backup demands corresponding to each of the plurality of working demands. The method additionally comprises packing into a single optical data unit a first backup demand corresponding to a first of the plurality of working demands and a second backup demand corresponding to a second of the plurality of working demands, wherein the first and second of the plurality of working demands share at least one common link in the optical transport network. The method also comprises unpacking the first and second backup demands from the optical data unit.
摘要翻译：根据本公开的一些实施例，用于光传送网络中的共享网格保护的方法包括通过光传输网络为多个工作需求中的每个提供路由。该方法还包括为与多个工作需求中的每一个相对应的备份需求提供路由。该方法还包括将单个光学数据单元包装成与多个工作需求中的第一个相对应的第一备份需求和对应于多个工作需求中的第二个的第二备份需求，其中多个工作需求在光传输网络中共享至少一个公共链路。该方法还包括从光学数据单元解包第一和第二备份需求。

40. 发明授权

US08938163B2 Method and system for hybrid multi-layer mesh restoration in a communication network 有权
标题翻译：通信网络混合多层网状网恢复方法与系统
公开(公告)号：US08938163B2
公开(公告)日：2015-01-20
申请号：US13348915
申请日：2012-01-12
申请人： Qiong Zhang , Xi Wang , Paparao Palacharia , Motoyoshi Sekiya
发明人： Qiong Zhang , Xi Wang , Paparao Palacharia , Motoyoshi Sekiya
IPC分类号： H04B10/00 , H04J14/00 , H04J14/02 , H04Q11/00 , H04L12/24
CPC分类号： H04Q11/0062 , H04J14/0284 , H04J14/0295 , H04L41/0654 , H04Q2011/0081
摘要： In accordance with embodiments of the present disclosure, a method may include sorting potential optical layer link failures in a network in an increasing order of failed traffic amount. The method may further include, for each potential optical link failure in increasing order of failed traffic amount: determining the additional higher layer link capacity required on existing higher layer links associated with the potential optical link failure using higher layer restoration of the potential optical link failure; determining the additional optical layer capacity required for restoring the existing higher layer links associated with the potential optical link failure using optical layer restoration; and selecting one of the higher layer and the optical layer as a restoration layer for restoration of the existing higher layer links associated with the potential optical link failure based on the determined additional higher layer link capacity and the determined additional optical layer capacity.
摘要翻译：根据本公开的实施例，一种方法可以包括按照故障业务量的增加顺序对网络中的潜在光层链路故障进行排序。该方法还可以包括：针对每个潜在的光链路故障以增加的故障业务量的顺序：使用更高层恢复潜在光链路故障来确定与潜在光链路故障相关联的现有较高层链路上所需的附加较高层链路容量 ; 使用光学层恢复来确定恢复与潜在光链路故障相关联的现有较高层链路所需的附加光层容量; 并且基于所确定的附加较高层链路容量和所确定的附加光层容量，选择较高层和光层之一作为恢复层，用于恢复与潜在光链路故障相关联的现有较高层链路。

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