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31. 发明申请

US20080221017A1 Pharmaceutical or cosmetic composition and use of a PKC inhibitor with an MMP inhibitor for inhibiting langerhans cell migration 审中-公开
标题翻译：药物或化妆品组合物和PKC抑制剂与MMP抑制剂的用途，用于抑制朗格汉斯细胞迁移
公开(公告)号：US20080221017A1
公开(公告)日：2008-09-11
申请号：US12073220
申请日：2008-03-03
申请人： Philippe Msika , Nathalie Piccardi , Antoine Piccirilli
发明人： Philippe Msika , Nathalie Piccardi , Antoine Piccirilli
IPC分类号： A61K38/00 , A61K31/07 , A61P17/00
CPC分类号： A61K31/13 , A61K8/41 , A61K8/68 , A61K31/045 , A61K31/56 , A61K36/48 , A61K2800/75 , A61Q19/00 , A61Q19/005 , A61K2300/00
摘要： The invention concerns a pharmaceutical or cosmetic composition, characterized in that it comprises at least a compound for inhibiting Langerhans' cell migration, said active compound being selected in the group consisting of protein kinase C (PKC) inhibiting compounds, matrix metalloprotease (MMP) inhibiting compounds, and combinations thereof, and at least a pharmaceutically or cosmetically acceptable carrier. Said composition enables to inhibit considerably Langerhans' cell migration induced by the presence of an allergenic agent.
摘要翻译：本发明涉及药物或化妆品组合物，其特征在于其至少包含用于抑制朗格汉斯细胞迁移的化合物，所述活性化合物选自蛋白激酶C（PKC）抑制化合物，基质金属蛋白酶（MMP）抑制剂化合物及其组合，以及至少一种药学上或化妆品上可接受的载体。所述组合物能够显着抑制由过敏原的存在引起的朗格汉斯细胞迁移。

32. 发明申请

US20070238777A1 Use of Furan Alkyls for Preparing a Drug for Treating Obesity and Cosmetically Treating Overweight 有权
标题翻译：使用呋喃烷基酯制备治疗肥胖和化妆品治疗超重的药物
公开(公告)号：US20070238777A1
公开(公告)日：2007-10-11
申请号：US11597634
申请日：2005-05-27
申请人： Antoine Piccirilli , Philippe Msika , Nathalie Piccardi
发明人： Antoine Piccirilli , Philippe Msika , Nathalie Piccardi
IPC分类号： A61K31/34
CPC分类号： A61K31/341 , A61K8/4973 , A61Q19/06
摘要： The invention relates to the use of one or several synthetic or natural furan alkyls for preparing a drug preventing and/or treating obesity or overweight. The use of one or several synthetic or natural furan alkyls for cosmetically treating local excessive weight is also disclosed. Said furan alkyls preferably correspond to formula (I), wherein identical or different R1, R2, R3et R4 are independently of each other a hydrogen atom, a C1-C35alkyl radical, C1-C35 alkenyl radical or a C1-C35 alcynyl radical, preferably C10-C22, wherein said alkyl, alkenyl and alcynyl radicals are substitutable and R1, R2, R3 are preferably a hydrogen atom.
摘要翻译：本发明涉及一种或多种合成或天然呋喃烷基酯用于制备预防和/或治疗肥胖或超重的药物的用途。还公开了一种或几种合成或天然呋喃烷基化合物用于化妆处理局部过量的用途。所述呋喃烷基优选对应于式（I），其中相同或不同的R 1，R 2，R 3和R 4 氢原子，C 1 -C 3 - 烷基，C 1 -C 3烷基，C 1 -C 3烷基，C 1 -C 3烷基， 35个链烯基或C 1 -C 35烷基，优选C 10 -C 22亚烷基 >，其中所述烷基，烯基和烷酰基是可取代的，并且R 1，R 2，R 3，R 3优选为氢原子。

33. 发明申请

US20060216249A1 Use of a cosmetic of pharmaceutical composition, comprising a lupeol-rich extract as an active ingredient for stimulating the synthesis of heat shock proteins 有权
标题翻译：使用药物组合物的化妆品，其包含富含富勒酚的提取物作为刺激热休克蛋白合成的活性成分
公开(公告)号：US20060216249A1
公开(公告)日：2006-09-28
申请号：US10564785
申请日：2004-07-19
申请人： Philippe Msika , Antoine Piccirilli , Nathalie Piccardi
发明人： Philippe Msika , Antoine Piccirilli , Nathalie Piccardi
IPC分类号： A61K8/97 , A61K36/48
CPC分类号： A61K8/97 , A61K31/045 , A61K36/48 , A61Q11/00 , A61Q19/00 , A61Q19/08
摘要： The present invention relates to the use of a lupeol-rich extract for the production of a cosmetic or pharmaceutical composition for treating and/or preventing a connective tissue degeneration. Said invention also relates to the use of a lupeol-rich extract for the production of a pharmaceutical composition for preventing and/or treating non-inflammatory articular pathologies, periodontal diseases and stretch marks. The invention also relates to the use of a lupeol-rich extract for the production of a cosmetic composition as a cicatrizing agent, a restructuring agent and an anti-sagging agent for skin and/or mucosae.
摘要翻译：本发明涉及富含富勒索的提取物用于生产用于治疗和/或预防结缔组织变性的化妆品或药物组合物的用途。所述发明还涉及富含富勒酸的提取物用于制备用于预防和/或治疗非炎性关节病变，牙周疾病和妊娠纹的药物组合物的用途。本发明还涉及富含富勒酸的提取物用于生产化妆品组合物作为痤疮剂，重组剂和用于皮肤和/或粘膜的抗流挂剂的用途。

34. 发明申请

US20140096577A1 PROCESS OF REACTIVE TRITURATION DIRECTLY ON AN OIL CAKE 有权
标题翻译：反应性直接进入油加工过程
公开(公告)号：US20140096577A1
公开(公告)日：2014-04-10
申请号：US14122081
申请日：2012-05-23
申请人： Jean-Luc Dubois , Antoine Piccirilli
发明人： Jean-Luc Dubois , Antoine Piccirilli
IPC分类号： C11C1/02 , C11C1/08
CPC分类号： C11C1/02 , C07C67/03 , C07C67/48 , C10L1/026 , C11B1/04 , C11B1/06 , C11B1/10 , C11B13/00 , C11C1/08 , C11C3/003 , Y02E50/10 , Y02E50/13 , Y02E50/30 , Y02E50/343 , Y02W30/47 , Y02W30/74
摘要： A process including at least one reactive trituration step which includes putting an oil cake including from 3% to 30% oil in contact with an anhydrous light alcohol and an alkaline catalyst under temperature and time conditions that are sufficient to allow for the extraction and transesterification of the vegetable oil and lead to the production of a mixture including fatty acid esters and glycerol, and a de-oiled cake including less than 3% oil. Also, a detoxified de-oiled cake as well as to a mixture of fatty acid esters with improved stability and resistance to oxidation.
摘要翻译：一种包括至少一种活性研磨步骤的方法，该方法包括在足以允许萃取和酯交换的温度和时间条件下将包含3％至30％油的油饼与无水轻质醇和碱性催化剂接触，植物油并导致生产包括脂肪酸酯和甘油的混合物，以及含油少于3％的脱油滤饼。另外，一种解毒的去油滤饼以及具有改善的稳定性和耐氧化性的脂肪酸酯的混合物。

35. 发明申请

US20120219709A1 USE OF HYDROXYCARBOXYLIC ACID OLIGOMERS AS ADHESIVES, MANUFACTURING METHOD AND HYDROXYCARBOXYLIC ACID OLIGOMERS OBTAINED 有权
标题翻译：使用羟基羧酸低聚物作为粘合剂，制造方法和羟基羧酸低聚物获得
公开(公告)号：US20120219709A1
公开(公告)日：2012-08-30
申请号：US13503882
申请日：2010-10-27
申请人： Antoine Piccirilli , Cedric Dever
发明人： Antoine Piccirilli , Cedric Dever
IPC分类号： B05D5/10 , C09J11/00 , C07C69/73 , C07C67/08 , C07C69/67
CPC分类号： C09J167/04 , C08G18/4283 , C08G63/06 , C08G2230/00 , C09J175/06
摘要： Disclosed is a method of using at least one functionalized hydroxycarboxylic acid oligomer as an adhesive for bonding materials. Also described is a process for manufacturing functionalized hydroxycarboxylic acid oligomers including at least one stage for polycondensation of a hydroxycarboxylic acid and a functional agent, as well as functionalized hydroxycarboxylic acid oligomers that can be obtained and the adhesive compositions that include them.
摘要翻译：公开了使用至少一种官能化羟基羧酸低聚物作为粘合材料的粘合剂的方法。还描述了制备官能化羟基羧酸低聚物的方法，其包括至少一个羟基羧酸和官能剂的缩聚阶段，以及可以获得的官能化羟基羧酸低聚物和包括它们的粘合剂组合物。

36. 发明申请

US20110142875A1 METHOD FOR OBTAINING ALGAE EXTRACTS AND USE OF THESE EXTRACTS 有权
标题翻译：获取提取物的方法和使用这些提取物
公开(公告)号：US20110142875A1
公开(公告)日：2011-06-16
申请号：US13003977
申请日：2009-07-17
申请人： Antoine Piccirilli
发明人： Antoine Piccirilli
IPC分类号： A61K36/02 , C07C29/76 , C11B3/00 , A23L1/28
CPC分类号： C12N1/066 , A23K10/30 , A23K50/80 , A23L17/60 , A61K8/37 , A61K8/9706 , A61K36/00 , A61K36/02 , A61Q19/00 , C05F11/10 , C05G3/0064 , C10L1/023 , C10L1/026 , C12N1/12 , Y02E50/13
摘要： A process for obtaining algae extracts, includes at least the following stages: a) pretreatment of an algal sample, b) rapid heating, c) application of pressure that is greater than or equal to 1 bar, d) instantaneous expansion to a pressure that is less than or equal to 1 bar, and e) recovery of the products that are obtained in d) in liquid, solid and/or gaseous form. The use of algae extract products obtained by the implementation of this process is also described.
摘要翻译：获得藻类提取物的方法至少包括以下阶段：a）预处理藻类样品，b）快速加热，c）施加大于或等于1巴的压力，d）瞬时膨胀至小于或等于1巴，e）回收在d）中以液体，固体和/或气体形式获得的产品。还描述了通过实施该方法获得的藻类提取物产品的使用。

37. 发明申请

US20100323984A1 COSMETIC ORAL AND/OR PARENTERAL USE OF GLUCOSAMINE OPTIONALLY IN COMBINATION WITH AT LEAST ONE POLYPHENOL COMPOUND, AND CORRESPONDING COMPOSITION 审中-公开
标题翻译：化妆品口服和/或使用葡萄糖胺选择性地与至少一种多酚化合物组合，以及相应的组合物
公开(公告)号：US20100323984A1
公开(公告)日：2010-12-23
申请号：US12445960
申请日：2007-10-19
申请人： Antoine Piccirilli , Patricia Manissier , Christiane Montastier
发明人： Antoine Piccirilli , Patricia Manissier , Christiane Montastier
IPC分类号： A61K31/7008 , A61K8/60 , A61K31/715 , A61P17/00 , A61Q19/00 , A61Q19/08 , A61Q19/06 , A61P17/02
CPC分类号： A61K31/05 , A61K8/60 , A61Q19/06 , A61Q19/08
摘要： The present invention relates to the cosmetic oral and/or parenteral use of glucosamine as an active agent for preventing and/or treating the cutaneous signs of ageing, optionally in combination with at least one polyphenol compound.The present invention also relates to a composition for oral and/or parenteral administration comprising, as active agent, the combination of glucosamine and of at least one polyphenol compound derived from pine bark.
摘要翻译：本发明涉及葡萄糖胺作为预防和/或治疗老化皮肤征象的活性剂的美容口服和/或肠胃外使用，任选地与至少一种多酚化合物组合。本发明还涉及用于口服和/或肠胃外给药的组合物，其包含作为活性剂的葡糖胺和至少一种衍生自松树皮的多酚化合物的组合。

38. 发明授权

US09090877B2 Method for obtaining algae extracts and use of these extracts 有权
标题翻译：获取藻类提取物和使用这些提取物的方法
公开(公告)号：US09090877B2
公开(公告)日：2015-07-28
申请号：US13003977
申请日：2009-07-17
申请人： Antoine Piccirilli
发明人： Antoine Piccirilli
IPC分类号： A01N65/00 , C12N1/06 , A61K36/00 , A23K1/14 , A23K1/18 , A23L1/337 , A61K8/37 , A61K8/97 , A61K36/02 , A61Q19/00 , C05F11/10 , C05G3/00 , C10L1/02 , C12N1/12
CPC分类号： C12N1/066 , A23K10/30 , A23K50/80 , A23L17/60 , A61K8/37 , A61K8/9706 , A61K36/00 , A61K36/02 , A61Q19/00 , C05F11/10 , C05G3/0064 , C10L1/023 , C10L1/026 , C12N1/12 , Y02E50/13
摘要： A process for obtaining algae extracts, includes at least the following stages: a) pretreatment of an algal sample, b) rapid heating, c) application of pressure that is greater than or equal to 1 bar, d) instantaneous expansion to a pressure that is less than or equal to 1 bar, and e) recovery of the products that are obtained in d) in liquid, solid and/or gaseous form. The use of algae extract products obtained by the implementation of this process is also described.
摘要翻译：获得藻类提取物的方法至少包括以下阶段：a）预处理藻类样品，b）快速加热，c）施加大于或等于1巴的压力，d）瞬时膨胀至小于或等于1巴，e）回收在d）中以液体，固体和/或气体形式获得的产品。还描述了通过实施该方法获得的藻类提取物产品的使用。

39. 发明授权

US08735615B2 Method for extracting unsaponifiables from renewable raw materials 有权
标题翻译：从可再生原料中提取不皂化物的方法
公开(公告)号：US08735615B2
公开(公告)日：2014-05-27
申请号：US13503509
申请日：2010-10-21
申请人： Antoine Piccirilli
发明人： Antoine Piccirilli
IPC分类号： C11B1/10 , C11B3/06
CPC分类号： C11B3/006 , C11B3/04 , C11B3/06
摘要： A method for extracting an unsaponifiable fraction from a renewable raw material selected among oilfruits, oleaginous seeds, oleoproteaginous seeds, seed husks, oil-yielding almonds, sprouts, stones and cuticles of fruits, high-fat raw materials from animals, algae, fungus or yeast, includes the following steps: a) dehydrating and packaging the renewable raw material, not resulting in any extraction of the fat; b) reactive crushing of the fatty packaged raw material in the presence of a light alcohol and a catalyst; c) evaporating the light alcohol; d) concentrating the liquid phase such as to obtain a concentrate including the unsaponifiable fraction diluted in fatty acid alkyl esters; e) saponifying the unsaponifiable concentrate; f) extracting the unsaponifiable fraction from the saponified mixture. The use of an unsaponifiable fraction or co-products obtained by implementing the method for preparing a composition such as a cosmetic, drug, food, or food additive or supplement is also described.
摘要翻译：从可可原料中提取不可皂化部分的方法，该可再生原料选自油果，油质种子，油蛋白质种子，种子壳，产油杏仁，芽果，果实的石头和角质层，动物，藻类，真菌等的高脂肪原料酵母，包括以下步骤：a）脱水和包装可再生原料，不会导致任何脂肪的提取; b）在轻质醇和催化剂存在下对脂肪包装原料的反应性破碎; c）蒸发轻酒精; d）浓缩液相，以获得包含稀释在脂肪酸烷基酯中的不皂化的级分的浓缩物; e）皂化不皂化的浓缩液; f）从皂化混合物中提取不皂化的部分。还描述了通过实施用于制备组合物如化妆品，药物，食品或食品添加剂或补充剂的方法获得的不皂化部分或共同产品的用途。

40. 发明授权

US07883729B2 Natural vegetable oil concentrated in unsaponifiable matters as food ingredient 有权
标题翻译：天然植物油集中在不皂化物质中作为食物成分
公开(公告)号：US07883729B2
公开(公告)日：2011-02-08
申请号：US10239298
申请日：2001-03-19
申请人： Carole Kohler , Philippe Msika , Antoine Piccirilli
发明人： Carole Kohler , Philippe Msika , Antoine Piccirilli
IPC分类号： A61K36/28 , A61K36/00
CPC分类号： C11B3/12 , A21D2/16 , A23D9/00 , A23L27/60 , A23L33/11 , A23L33/115 , A23L33/15 , A23V2002/00 , A61K8/922 , A61K31/01 , A61K31/015 , A61K31/355 , A61K31/56 , A61K45/06 , A61Q19/00 , A61Q19/08 , A61K2300/00 , A23V2250/188 , A23V2250/712 , A23V2250/21368 , A23V2250/211 , A23V2250/1874
摘要： The invention concerns a natural vegetable oil selected among palm oil, corn germ oil, sunflower oil and canola oil, concentrated in unsaponifiable matters, such that said oil unsaponifiable matter content is 3 to 15% m/m. Said concentrated natural vegetable oil constitutes a novel food ingredient enriched in particular in vitamin E and phytosterol, useful as favored food source in vitamin E and phytosterol, meeting recommended daily intake.
摘要翻译：本发明涉及一种选自棕榈油，玉米胚芽油，向日葵油和卡诺拉油中的天然植物油，其浓缩在不皂化物质中，使得所述油不皂化物质含量为3至15％m / m。所述浓缩天然植物油构成特别富含维生素E和植物甾醇的新型食品成分，可用作维生素E和植物甾醇中有利的食物来源，满足推荐的每日摄入量。

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