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31. 发明申请

US20100204559A1 DEVICE AND METHOD FOR DETERMINING ANALYTE LEVELS 有权
公开(公告)号：US20100204559A1
公开(公告)日：2010-08-12
申请号：US12763016
申请日：2010-04-19
申请人： Mark C. Shults , Stuart J. Updike , Rathbun K. Rhodes
发明人： Mark C. Shults , Stuart J. Updike , Rathbun K. Rhodes
IPC分类号： A61B5/145
CPC分类号： A61B5/14865 , A61B5/0004 , A61B5/14532 , A61B5/1495 , C12Q1/006
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

32. 发明申请

US20100160760A1 DEVICE AND METHOD FOR DETERMINING ANALYTE LEVELS 有权
标题翻译：用于确定分析水平的装置和方法
公开(公告)号：US20100160760A1
公开(公告)日：2010-06-24
申请号：US12696003
申请日：2010-01-28
申请人： Mark C. Shults , Stuart J. Updike , Rathbun K. Rhodes , Barbara J. Gilligan , Mark A. Tapsak
发明人： Mark C. Shults , Stuart J. Updike , Rathbun K. Rhodes , Barbara J. Gilligan , Mark A. Tapsak
IPC分类号： A61B5/145
CPC分类号： C12Q1/006 , A61B5/0031 , A61B5/14532 , A61B5/14558 , A61B5/14865
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
摘要翻译：描述了用于确定分析物水平的装置和方法。装置和方法允许植入分析物监测装置，例如葡萄糖监测装置，其导致输送可靠的血液流以将样品输送到植入装置。这些设备在传感器区域中包括独特的架构布置，可以在长时间内获得准确的数据。

33. 发明申请

US20090045055A1 SENSOR HEAD FOR USE WITH IMPLANTABLE DEVICES 有权
标题翻译：传感器头用于可移植设备
公开(公告)号：US20090045055A1
公开(公告)日：2009-02-19
申请号：US12260017
申请日：2008-10-28
申请人： Rathbun K. Rhodes , Mark C. Shults , Mark A. Tapsak , James H. Brauker
发明人： Rathbun K. Rhodes , Mark C. Shults , Mark A. Tapsak , James H. Brauker
IPC分类号： G01N27/26
CPC分类号： G01N27/3272 , A61B5/14532 , A61B5/14865 , C12Q1/002 , C12Q1/006 , G01N33/48707 , G01N33/48785
摘要： The present invention provides a sensor head for use in an implantable device that measures the concentration of an analyte in a biological fluid which includes: a non-conductive body; a working electrode, a reference electrode and a counter electrode, wherein the electrodes pass through the non-conductive body forming an electrochemically reactive surface at one location on the body and forming an electronic connection at another location on the body, further wherein the electrochemically reactive surface of the counter electrode is greater than the surface area of the working electrode; and a multi-region membrane affixed to the nonconductive body and covering the working electrode, reference electrode and counter electrode. In addition, the present invention provides an implantable device including at least one of the sensor heads of the invention and methods of monitoring glucose levels in a host utilizing the implantable device of the invention.
摘要翻译：本发明提供了一种用于可植入装置的传感器头，其用于测量生物流体中分析物的浓度，其包括：非导电体; 工作电极，参考电极和对电极，其中电极穿过非导电体，其在身体的一个位置处形成电化学反应性表面，并在身体的另一位置形成电子连接，其中电化学反应性对电极的表面大于工作电极的表面积; 以及附着在非导体上并覆盖工作电极，参比电极和对电极的多区域膜。此外，本发明提供一种可植入装置，其包括本发明的至少一个传感器头和利用本发明的可植入装置监测主机中的葡萄糖水平的方法。

34. 发明授权

US07136689B2 Device and method for determining analyte levels 有权
标题翻译：用于确定分析物水平的装置和方法
公开(公告)号：US07136689B2
公开(公告)日：2006-11-14
申请号：US11039269
申请日：2005-01-19
申请人： Mark C. Shults , Stuart J. Updike , Rathbun K. Rhodes , Barbara J. Gilligan , Mark A. Tapsak
发明人： Mark C. Shults , Stuart J. Updike , Rathbun K. Rhodes , Barbara J. Gilligan , Mark A. Tapsak
IPC分类号： A61B5/00 , A61B5/05
CPC分类号： C12Q1/006 , A61B5/0031 , A61B5/14532 , A61B5/14558 , A61B5/14865
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that slows accurate date to be obtained over long periods of time.
摘要翻译：描述用于确定分析物水平的装置和方法。装置和方法允许植入分析物监测装置，例如葡萄糖监测装置，其导致输送可靠的血液流以将样品输送到植入装置。这些设备在传感器区域中包括独特的架构布置，可以减慢长时间获得的准确日期。

35. 发明授权

US06862465B2 Device and method for determining analyte levels 有权
标题翻译：用于确定分析物水平的装置和方法
公开(公告)号：US06862465B2
公开(公告)日：2005-03-01
申请号：US09916858
申请日：2001-07-27
申请人： Mark C. Shults , Stuart J. Updike , Rathbun K. Rhodes , Barbara J. Gilligan , Mark A. Tapsak
发明人： Mark C. Shults , Stuart J. Updike , Rathbun K. Rhodes , Barbara J. Gilligan , Mark A. Tapsak
IPC分类号： A61B5/00 , C12Q1/00 , A61F7/00
CPC分类号： C12Q1/006 , A61B5/0031 , A61B5/14532 , A61B5/14558 , A61B5/14865
摘要： Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
摘要翻译：描述了用于确定分析物水平的装置和方法。装置和方法允许植入分析物监测装置，例如葡萄糖监测装置，其导致输送可靠的血液流以将样品输送到植入装置。这些设备在传感器区域中包括独特的架构布置，可以在长时间内获得准确的数据。

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