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31. 发明授权

US08560053B2 Methods and apparatuses for endoscopic retrograde cholangiopancreatography 失效
标题翻译：内窥镜逆行胰胆管造影的方法和装置
公开(公告)号：US08560053B2
公开(公告)日：2013-10-15
申请号：US12843001
申请日：2010-07-23
申请人： Pankaj Jay Pasricha
发明人： Pankaj Jay Pasricha
IPC分类号： A61B6/00 , A61B1/00
CPC分类号： A61B1/2733 , A61B1/00094 , A61B1/015 , A61B1/018 , A61B17/3474 , A61B17/3478 , A61B2017/306 , A61M25/0084
摘要： A method is disclosed for distending a body lumen in the performance of endoscopic retrograde cholangiopancreatography (ERCP). The method comprises insufflating the body lumen with contrast agent to distend the body lumen. The contrast agent includes gas.
摘要翻译：公开了一种在内窥镜逆行胰胆管造影（ERCP）的表现中扩张体腔的方法。该方法包括用造影剂吹动体腔以扩张体腔。造影剂包括气体。

32. 发明授权

US08467884B2 Gastrointestinal electrical stimulation 有权
标题翻译：胃肠电刺激
公开(公告)号：US08467884B2
公开(公告)日：2013-06-18
申请号：US11681249
申请日：2007-03-02
申请人： Jiande Chen , Pankaj Jay Pasricha
发明人： Jiande Chen , Pankaj Jay Pasricha
IPC分类号： A61N1/05
CPC分类号： A61N1/36007
摘要： The present invention is directed to a method of stimulating the vagus nerve of a subject.
摘要翻译：本发明涉及刺激受试者的迷走神经的方法。

33. 发明申请

US20120164139A1 Dopamine 3 receptor agonist and antagonist treatment of gastrointestinal motility disorders 审中-公开
标题翻译：多巴胺3受体激动剂和拮抗剂治疗胃肠动力障碍
公开(公告)号：US20120164139A1
公开(公告)日：2012-06-28
申请号：US13413480
申请日：2012-03-06
申请人： Pankaj Jay Pasricha , Maria-Adelaide Micci
发明人： Pankaj Jay Pasricha , Maria-Adelaide Micci
IPC分类号： A61K39/395 , A61K31/5383 , A61K31/565 , A61K31/57 , A61K31/573 , A61K31/606 , A61K38/13 , A61K35/60 , A61K33/24 , A61K31/727 , A61K31/4439 , A61K31/426 , A61K31/4164 , A61K33/06 , A61K31/7048 , A61K31/55 , A61P1/00 , A61P29/00 , A61P31/00 , A61P25/00 , A61P1/06 , A61P1/04 , A61P7/10 , A61P37/02 , A61P3/04 , A61P1/08 , A61K31/40
CPC分类号： A61K31/135 , A61K31/445 , A61K31/4745 , A61K31/485 , A61K31/525 , A61K31/56 , A61K31/727
摘要： Provided herein are methods of treating gastrointestinal motility disorders by targeting the dopamine 3 receptor (D3R). A D3R agonist is administered to a subject to decrease gastrointestinal motility to treat the disorder. A D3R antagonist is administered to a subject to decrease gastrointestinal motility to treat the disorder.
摘要翻译：本文提供了通过靶向多巴胺3受体（D3R）来治疗胃肠蠕动障碍的方法。向受试者施用D3R激动剂以降低胃肠道运动以治疗该病症。对受试者施用D3R拮抗剂以降低胃肠蠕动以治疗病症。

34. 发明申请

US20120071867A1 DIODE LASER SYSTEMS AND METHODS FOR ENDOSCOPIC TREATMENT OF TISSUE 审中-公开
标题翻译：二极管激光系统和组织内镜治疗方法
公开(公告)号：US20120071867A1
公开(公告)日：2012-03-22
申请号：US13051891
申请日：2011-03-18
申请人： Andrew Ryan , Ramsey Shanbaky , Pankaj Jay Pasricha
发明人： Andrew Ryan , Ramsey Shanbaky , Pankaj Jay Pasricha
IPC分类号： A61B18/22
CPC分类号： A61B18/24 , A61N5/062 , A61N2005/0609 , A61N2005/0662 , A61N2005/067
摘要： Embodiments of the present invention provide improved laser systems and methods for endoscopic laser treatment of abnormal tissue such as abnormal mucosal tissue, for example esophageal dysplasia that is also referred to as Barrett's esophagus (BE). The systems and methods described here can also be used in many applications where treatment of shallow surface layers with minimal damage to the tissue beneath is desirable, for example BE tissue comprising hemoglobin. In many embodiments, the system is configured to emit light energy having an optical wavelength to treat tissue having oxygenated hemoglobin.
摘要翻译：本发明的实施例提供了改进的激光系统和用于内窥镜激光治疗异常组织如异常粘膜组织的激光系统和方法，例如也被称为Barrett食管（BE）的食管发育不良。这里描述的系统和方法也可以用于许多应用，其中处理对最下层组织的损伤最小的浅表面层，例如包含血红蛋白的BE组织。在许多实施例中，该系统被配置为发射具有光波长的光能以处理具有氧合血红蛋白的组织。

35. 发明申请

US20120022322A1 Methods and Devices for Treating Obesity 有权
标题翻译：治疗肥胖的方法和设备
公开(公告)号：US20120022322A1
公开(公告)日：2012-01-26
申请号：US13195354
申请日：2011-08-01
申请人： Pankaj Jay Pasricha
发明人： Pankaj Jay Pasricha
IPC分类号： A61F2/02
CPC分类号： A61F5/003 , A61F5/0003 , A61F5/0069 , G06F19/00
摘要： Methods and devices for treating obesity. Pressure is applied to gastric walls in at least one segment of a stomach such that the pressure distends the gastric walls and induces satiety. A hollow capsule can be used to distend the gastric walls. Alternatively, a doughnut- shaped ring may be inflated to an amount sufficient to create intragastric tension and induce satiety. A c-ring including at least one balloon may be placed at a segment of the stomach, where the balloon inflates to a size that creates tension at the segment. A biocompatible material can be injected into the fundus and antrum of the stomach to stiffen the gastric wall to create a fullness feeling.
摘要翻译：治疗肥胖的方法和装置。在胃的至少一个部分的胃壁施加压力，使得压力膨胀胃壁并诱导饱腹感。可以使用中空胶囊来扩张胃壁。或者，可以将面团形的环充气至足以产生胃内张力并引起饱腹感的量。包括至少一个气囊的c环可以放置在胃的一部分处，其中气囊膨胀到在该段处产生张力的尺寸。可以将生物相容性材料注射到胃底和胃窦中，以加强胃壁以产生丰满感。

36. 发明授权

US08021355B2 System, kit, and method of transgastric removal of visceral fat and other related methods 有权
标题翻译：经胃清除内脏脂肪的系统，试剂盒和方法等相关方法
公开(公告)号：US08021355B2
公开(公告)日：2011-09-20
申请号：US11202855
申请日：2005-08-12
申请人： Pankaj Jay Pasricha
发明人： Pankaj Jay Pasricha
IPC分类号： A61M1/00
CPC分类号： A61B1/273 , A61B1/00165 , A61B17/29 , A61B17/320016 , A61B2217/005 , A61B2217/007 , A61M1/0058
摘要： Embodiments of systems, kits, and methods to perform transgastric procedures to removing visceral fat in the peritoneal cavity are described. Am embodiment includes deliberately breaching a wall of a gastrointestinal tract to enter the peritoneal cavity to physically remove visceral fat adjacent or on outer surfaces of organs located within the peritoneal cavity. A user can identify regions of visceral fat desired to be removed. A user can insert an instrument through the mouth into the stomach of the patient. The user makes an incision in the wall of the organ adjacent the visceral fat to be removed. Using visual guidance for the instrument, the user passes a distal end of the instrument through an opening formed by the incision into the peritoneal cavity. A user utilizes removes the visceral fat from outer surfaces of the organ, the opening is closed, and the tool is removed from the patient.
摘要翻译：描述了在腹膜腔中进行胃内过程去除内脏脂肪的系统，试剂盒和方法的实施方案。实施方案包括有意地破坏胃肠道的壁以进入腹膜腔以物理去除位于腹膜腔内的器官相邻或外表面的内脏脂肪。用户可以识别想要去除的内脏脂肪的区域。用户可以将仪器通过口插入患者的胃中。使用者在靠近内脏脂肪的脏器的壁上进行切口以被去除。使用仪器的视觉指导，使用者将仪器的远端通过由切口形成的开口传入腹腔。使用者利用从器官的外表面去除内脏脂肪，开口关闭，并且将工具从患者身上取出。

37. 发明申请

US20110028833A1 METHODS AND APPARATUSES FOR ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY 失效
标题翻译：内镜手术切除术的方法与装置
公开(公告)号：US20110028833A1
公开(公告)日：2011-02-03
申请号：US12843001
申请日：2010-07-23
申请人： Pankaj Jay Pasricha
发明人： Pankaj Jay Pasricha
IPC分类号： A61B6/00
CPC分类号： A61B1/2733 , A61B1/00094 , A61B1/015 , A61B1/018 , A61B17/3474 , A61B17/3478 , A61B2017/306 , A61M25/0084
摘要： A method is disclosed for distending a body lumen in the performance of endoscopic retrograde cholangiopancreatography (ERCP). The method comprises insufflating the body lumen with contrast agent to distend the body lumen. The contrast agent includes gas.
摘要翻译：公开了一种在内窥镜逆行胰胆管造影（ERCP）的表现中扩张体腔的方法。该方法包括用造影剂吹动体腔以扩张体腔。造影剂包括气体。

38. 发明授权

US07659306B2 Method of increasing gastric emptying 失效
标题翻译：增加胃排空的方法
公开(公告)号：US07659306B2
公开(公告)日：2010-02-09
申请号：US11266686
申请日：2005-11-03
申请人： Pankaj Jay Pasricha , Maria-Adelaide Micci
发明人： Pankaj Jay Pasricha , Maria-Adelaide Micci
IPC分类号： A61K31/40
CPC分类号： A61K31/135 , A61K31/445 , A61K31/4745 , A61K31/485 , A61K31/525 , A61K31/56 , A61K31/727
摘要： The invention discloses the administration of nafadotride partially reverse the effect of dopamine on gastric emptying in patients suffering from gastroesophageal reflux.
摘要翻译：本发明公开了给予奈非多肽部分逆转多巴胺对胃食管反流患者胃排空的作用。

39. 发明申请

US20080312678A1 Methods and Devices for Treating Obesity 审中-公开
标题翻译：治疗肥胖的方法和设备
公开(公告)号：US20080312678A1
公开(公告)日：2008-12-18
申请号：US11914073
申请日：2006-05-11
申请人： Pankaj Jay Pasricha
发明人： Pankaj Jay Pasricha
IPC分类号： A61M29/00
CPC分类号： A61F5/003 , A61F5/0003 , A61F5/0069
摘要： Methods and devices for treating obesity. Pressure is applied to gastric walls in at least one segment of a stomach such that the pressure distends the gastric walls and induces satiety. A hollow capsule can be used to distend the gastric walls. Alternatively, a doughnut-shaped ring may be inflated to an amount sufficient to create intragastric tension and induce satiety. A c-ring including at least one balloon may be placed at a segment of the stomach, where the balloon inflates to a size that creates tension at the segment. A biocompatible material can be injected into the fundus and antrum of the stomach to stiffen the gastric wall to create a fullness feeling.
摘要翻译：治疗肥胖的方法和装置。在胃的至少一个部分的胃壁施加压力，使得压力膨胀胃壁并诱导饱腹感。可以使用中空胶囊来扩张胃壁。或者，环形环可以膨胀至足以产生胃内张力并引起饱腹感的量。包括至少一个气囊的c环可以放置在胃的一部分处，其中气囊膨胀到在该段处产生张力的尺寸。可以将生物相容性材料注射到胃底和胃窦中，以加强胃壁以产生丰满感。

40. 发明授权

US5846235A Endoscopic cryospray device 失效
标题翻译：内窥镜冷冻喷雾装置
公开(公告)号：US5846235A
公开(公告)日：1998-12-08
申请号：US840290
申请日：1997-04-14
申请人： Pankaj Jay Pasricha , Anthony N. Kalloo , John G. Baust , Lawrence Potorff
发明人： Pankaj Jay Pasricha , Anthony N. Kalloo , John G. Baust , Lawrence Potorff
IPC分类号： A61B17/00 , A61B18/02 , F25B9/02 , A61B17/36
CPC分类号： F25B9/02 , A61B18/0218 , A61B2017/00292 , A61B2018/0212
摘要： A cryoprobe instrument for endoscopic use has been provided that permits the delivery of liquid or gaseous cryogens in the form of a spray. In an embodiment, the cryoprobe instrument includes an elongated, flexible tube having a fluid passage defined therethrough; a proximal connector portion provided at the proximal end of the tube for coupling the tube to a pressurized source of cryogenic refrigerant; and a nozzle tip mounted to the distal end of the tube. The nozzle tip has an outlet orifice constructed and arranged such that through the Joule-Thompson effect, cryogenic refrigerant exiting through the outlet orifice rapidly and substantially expands and cools.
摘要翻译：已经提供了用于内窥镜使用的冷冻探头仪器，其允许以喷雾形式输送液体或气态冷冻剂。在一个实施例中，冷冻探头仪器包括细长的柔性管，其具有通过其限定的流体通道; 近端连接器部分，设置在管的近端处，用于将管连接到加压的低温制冷剂源; 以及安装到管的远端的喷嘴尖端。喷嘴尖端具有构造和布置成使得通过焦耳 - 汤普森效应的出口孔口，通过出口孔排出的低温制冷剂快速且基本上膨胀和冷却。

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