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    • 32. 发明授权
    • Synthesis of isoimide of chlorins and bacteriochlorins and their use for
diagnosis and treatment of cancer
    • 二氢卟酚和细菌二氢卟酚的异构酰亚胺的合成及其在癌症诊断和治疗中的应用
    • US5864035A
    • 1999-01-26
    • US812029
    • 1997-03-06
    • Ravindra K. PandeyAndrei N. KozyrevThomas J. Dougherty
    • Ravindra K. PandeyAndrei N. KozyrevThomas J. Dougherty
    • A61K41/00C07D471/22C07D491/22C07D487/22
    • C07D471/22A61K41/0071C07D491/22
    • Compounds having utility as light absorbing compounds, especially in the area of photodynamic therapy. Such compounds have the formula: ##STR1## where z is .dbd.O or NR.sub.14 ; R.sub.14 is alkyl or substituted alkyl; R.sub.1 is an amino acid group, a polyamine group, a polyether group or OR.sub.13 where R.sub.13 is alkyl; R.sub.4 through R.sub.11 are --H, --OH alkyl, alkoxy, alkenyl, alkylene, aryl, or aryloxy, or a carbonyl containing group, wherein carbon containing groups may be substituted with carbonyl, hydroxy, phosphoro, carboxy, halo, sulfo, amino and ether substituents, provided that; R.sub.4 may be taken together with R.sub.7 to form .dbd.O; R.sub.8 may be taken together with R.sub.9 to form .dbd.O; R.sub.10 may be taken together with R.sub.11 to form .dbd.O; and R.sub.4 and R.sub.7 may together form a chemical bond and R.sub.8 and R.sub.11 may together form a chemical bond; and R.sub.12 is hydrogen or lower alkyl; provided that if one z is O, the other z is --NR.sub.14.
    • 具有作为光吸收化合物用途的化合物,特别是在光动力疗法领域。 这些化合物具有下式:其中z为= O或NR14; R14是烷基或取代的烷基; R1是氨基酸基团,多胺基团,聚醚基团或OR13,其中R13是烷基; R4至R11是-H,-OH烷基,烷氧基,烯基,亚烷基,芳基或芳氧基或含羰基,其中含碳基团可以被羰基,羟基,磷酰基,羧基,卤素,磺基,氨基和 醚取代基,条件是 R4可以与R7一起形成= O; R8可以与R9一起形成= O; R10可以与R11一起形成= O; 并且R 4和R 7可以一起形成化学键,并且R 8和R 11可以一起形成化学键; 和R 12是氢或低级烷基; 条件是如果一个z是O,另一个Z是-NR 14。
    • 33. 发明授权
    • Vent cap with electrolyte drain and explosion attenuation capabilities
    • 排气盖具有电解液排水和防爆功能
    • US5284720A
    • 1994-02-08
    • US68415
    • 1993-05-27
    • David A. ThuerkDebra L. SmithThomas J. DoughertyRandy K. Hulsebus
    • David A. ThuerkDebra L. SmithThomas J. DoughertyRandy K. Hulsebus
    • H01M2/04H01M2/12
    • H01M2/127H01M2/1217
    • The explosion attenuating vent cap for storage batteries according to the present invention features an electrolyte drain and baffle design adapted for maximizing return to the battery of any liquid which may enter the vent from vibration, tilting, overheating, overcharge and the like. The vent barrel(s) include a step to assist in closure of the fill openings, and baffles within the vent prevent accumulation of electrolyte within the cap. The arrangement of the entrance to the gas escape passage (leading through an explosion attenuation device such as a disc of microporous polymer) is located on the center lines of the barrel and at the highest possible location within the vent to minimize the intrusion of electrolyte into the attenuation material. This location of the entrance prevents accumulation of electrolyte at that location. Preferably, the vent cap is of the ganged variety, i.e. useful for simultaneously capping three or more fill openings of the battery.
    • 根据本发明的用于蓄电池的爆炸衰减通气帽的特征在于电解液排泄和挡板设计,其适于最大程度地使可能从振动,倾斜,过热,过充电等进入通风口的任何液体的电池返回。 排气筒包括一个辅助关闭填充开口的步骤,并且通气孔内的挡板防止电解液在盖内积聚。 气体排放通道的入口(通过诸如微孔聚合物盘的爆炸衰减装置)的布置位于筒的中心线和通风口内的最高可能位置处,以最小化电解质入侵 衰减材料。 入口处的这个位置防止了电解液在该位置积聚。 优选地,通气盖是组合的,可用于同时封盖电池的三个或更多个填充开口。
    • 34. 发明授权
    • Long lived dual battery with automatic latching switch
    • 长寿命双电池带自动闭锁开关
    • US5204610A
    • 1993-04-20
    • US656772
    • 1991-02-15
    • John R. PiersonThomas J. DoughertyRonald C. Klassen
    • John R. PiersonThomas J. DoughertyRonald C. Klassen
    • H02J9/06
    • H02J9/061Y10T307/625
    • A latching automatic dual battery switch employs a first comparator to determine that a condition requiring engagement of a secondary battery exists. For example, a primary battery voltage is below a predetermined threshold, current drawn from the primary battery exceeds a predetermined threshold or ambient temperature is below a predetermined threshold. Engagement of an ignition switch is detected and used to clock the output of the comparator to a trigger circuit. The trigger circuit activates the triggerable switch on the leading edge of a signal generated by the detector circuit to connect a secondary battery or power source in parallel with the primary power source. The trigger circuit is leading edge activated so that conditions immediately prior to engagement of the ignition switch determine if the secondary battery is engaged. This avoids engaging the secondary battery as a result of a load surge dragging down the voltage after activation of an ignition switch. In addition, when the ignition switch is released, a timing circuit is engaged to limit the additional time during which the secondary battery is switched in the circuit. The automatic engagement of the secondary battery eliminates the need for manually switching to an emergency backup and manually disengaging the emergency backup after a vehicle is started.
    • 闩锁自动双电池开关采用第一比较器来确定需要二次电池接合的状况。 例如,一次电池电压低于预定阈值,从初级电池抽出的电流超过预定阈值或环境温度低于预定阈值。 检测点火开关的接合,并将其用于将比较器的输出定时到触发电路。 触发电路激活由检测器电路产生的信号的前沿上的可触发开关,以将二次电池或电源与主电源并联连接。 触发电路处于前沿被激活,使得紧接在点火开关接合之前的状态确定二次电池是否接合。 这避免了由于在启动点火开关之后负载浪涌向下拖动电压而使二次电池接合。 此外,当点火开关被释放时,接合定时电路以限制二次电池在电路中切换的附加时间。 二次电池的自动接合消除了在车辆启动之后手动切换到紧急备用和手动分离紧急备用的需要。
    • 37. 发明授权
    • Engine having opposed pistons and opposed cylinders and side dual power output shafts
    • 发动机具有相对的活塞和相对的气缸和侧面双功率输出轴
    • US08800506B2
    • 2014-08-12
    • US12901235
    • 2010-10-08
    • Thomas J. Dougherty
    • Thomas J. Dougherty
    • F01B7/12F02B75/24F02B25/08
    • F02B75/246F01B7/12F02B25/08F02B75/24
    • The engine includes a cylinder; a first piston and a second piston that reciprocate in the cylinder wherein the first piston has a first end piston head; a first piston rod attached to the first piston at a second end of the first piston opposite the first end; wherein the second piston has a first end forming a second piston head; a second piston rod attached to the second piston at a second end opposite the first end of the second piston; a first connecting rod connected to the first piston rod and coupled to a power output shaft; and a second connecting rod connected to the second piston rod and coupled to the power output shaft. The first and second piston head move away from each other on a first power stroke of the first piston and a second power stroke of the second piston.
    • 发动机包括气缸; 第一活塞和第二活塞,其在所述气缸中往复运动,其中所述第一活塞具有第一端活塞头; 在所述第一活塞的与所述第一端相对的第二端处附接到所述第一活塞的第一活塞杆; 其中所述第二活塞具有形成第二活塞头的第一端; 在与第二活塞的第一端相对的第二端附接到第二活塞的第二活塞杆; 连接到第一活塞杆并联接到动力输出轴的第一连杆; 以及连接到第二活塞杆并联接到动力输出轴的第二连杆。 第一和第二活塞头在第一活塞的第一动力冲程和第二活塞的第二动力冲程上彼此远离。