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    • 32. 发明授权
    • Cyclic amine compound
    • 环胺化合物
    • US07601734B2
    • 2009-10-13
    • US11578169
    • 2005-04-08
    • Toshihito KumagaiToshio NakamuraYuri AmadaYoshinori Sekiguchi
    • Toshihito KumagaiToshio NakamuraYuri AmadaYoshinori Sekiguchi
    • A61K31/44A61P25/18A61P25/24
    • C07D491/048C07D471/04C07D495/04
    • An object of the present invention is to provide a cyclic amine compound which has a potent inhibitory effect on the binding of α2C-adrenoceptor and is useful in preventing and treating disorders attributable to α2C-adrenoceptor.The above-described object is solved by the following cyclic amine compound, etc., wherein X is O, S, SO, SO2 or NR2, etc.; R1 is a hydrogen atom, a cyano group, a carboxyl group, a C2-C13 alkoxycarbonyl group, a carbamoyl group, etc.; Ar1 and Ar2 are the same or different and each represent an aryl or heteroaryl group which may be substituted by 1 to 3 substituents and so on; ring B is a benzene ring may be substituted by 1 to 3 substituents and so on; n is an integer from 1 to 10; and p and q are the same or different and each represent an integer of 1 or 2.
    • 本发明的目的是提供对α2C-肾上腺素能受体的结合具有强效抑制作用的环胺化合物,可用于预防和治疗归因于α2C-肾上腺素受体的病症。 上述目的通过以下环胺化合物等来解决,其中X是O,S,SO,SO 2或NR 2等; R1是氢原子,氰基,羧基,C2-C13烷氧基羰基,氨基甲酰基等; Ar 1和Ar 2相同或不同,各自表示可被1〜3个取代基等取代的芳基或杂芳基; 环B为苯环可被1〜3个取代基取代等; n是1至10的整数; p和q相同或不同,各自表示1或2的整数。
    • 33. 发明申请
    • Cyclic Amine Compound
    • 环胺化合物
    • US20070244145A1
    • 2007-10-18
    • US11578169
    • 2005-04-08
    • Toshihito KumagaiToshio NakamuraYuri AmadaYoshinori Sekiguchi
    • Toshihito KumagaiToshio NakamuraYuri AmadaYoshinori Sekiguchi
    • A61K31/44A61P25/18A61P25/24
    • C07D491/048C07D471/04C07D495/04
    • An object of the present invention is to provide a cyclic amine compound which has a potent inhibitory effect on the binding of α2C-adrenoceptor and is useful in preventing and treating disorders attributable to α2C-adrenoceptor. The above-described object is solved by the following cyclic amine compound, etc., wherein X is O, S, SO, SO2 or NR2, etc.; R1 is a hydrogen atom, a cyano group, a carboxyl group, a C2-C13 alkoxycarbonyl group, a carbamoyl group, etc.; Ar1 and Ar2 are the same or different and each represent an aryl or heteroaryl group which may be substituted by 1 to 3 substituents and so on; ring B is a benzene ring may be substituted by 1 to 3 substituents and so on; n is an integer from 1 to 10; and p and q are the same or different and each represent an integer of 1 or 2.
    • 本发明的目的是提供对α2C-肾上腺素能受体的结合具有强效抑制作用的环胺化合物,可用于预防和治疗归因于α2C-肾上腺素受体的病症。 上述目的通过以下环胺化合物等来解决,其中X是O,S,SO,SO 2或NR 2等; R 1是氢原子,氰基,羧基,C 1 -C 13烷氧基羰基,氨基甲酰基等 。 Ar 1和Ar 2相同或不同,各自表示可被1至3个取代基等取代的芳基或杂芳基; 环B为苯环可被1〜3个取代基取代等; n是1至10的整数; p和q相同或不同,各自表示1或2的整数。
    • 37. 发明授权
    • Turntable and disk driving device
    • 转盘和磁盘驱动装置
    • US06549508B1
    • 2003-04-15
    • US09636279
    • 2000-08-10
    • Yukio MatsumotoSatoshi OtomoToshio Nakamura
    • Yukio MatsumotoSatoshi OtomoToshio Nakamura
    • G11B2300
    • G11B17/022
    • A turntable can be manufactured inexpensively using a comparatively inexpensive material and in accordance with ordinary injection molding technique and mold management. A thin-walled cylindrical fixing portion having an insertion hole, into which a rotational shaft is pressed, is formed at a central portion of the turntable. A thin-walled cylindrical reinforcing portion, which is concentric with the fixing portion and has a large diameter, is formed at the outer circumferential side of the fixing portion. Reinforcing rib portions are provided radially between the fixing portion and the reinforcing portion. In this way, deformation due to sink or the like does not occur at the time of injection molding, and extracting force of the rotational shaft which was pressed into the insertion hole can be adjusted to a predetermined value.
    • 可以使用相对便宜的材料并且根据通常的注塑技术和模具管理廉价地制造转台。 在转盘的中央部形成有具有插入孔的薄壁圆柱形固定部,旋转轴被压入其中。 在固定部分的外周侧形成有与固定部分同心且具有大直径的薄壁圆柱形加强部分。 增强肋部分径向设置在固定部分和加强部分之间。 以这种方式,在注射成型时不会发生由于凹陷等引起的变形,并且可以将压入插入孔的旋转轴的提取力调节到预定值。
    • 39. 发明授权
    • Optical filter module and optical amplification using it
    • 光滤波器模块和光放大使用它
    • US5790301A
    • 1998-08-04
    • US805559
    • 1997-02-25
    • Hidenari MaedaTakashi WatanabeToshio NakamuraManabu Wakabayashi
    • Hidenari MaedaTakashi WatanabeToshio NakamuraManabu Wakabayashi
    • G02B5/20G02B6/34G02B6/42H01S3/067H01S3/10H04B10/079H04B10/27H04B10/29H04B10/297H04J14/02H01S3/00G02B27/14
    • G02B6/4246G02B6/29364G02B6/29367H01S3/10023H04B10/2537H01S3/06787H04J14/02
    • In an optical filter module and an optical amplification apparatus for a wavelength division multiplex (WDM light), the respective wavelength intervals of the plural passing center wavelengths and the filter characteristics in the vicinities of the respective center wavelengths can be set independently, whereby the BPF1 is provided with different passing center wavelengths .lambda.1, .lambda.2 . . . .lambda.n and different filter characteristics. And, when the WDM signal light including wavelengths .lambda.1, .lambda.2 . . . .lambda.n is inputted into the port 2-1a, the .lambda.k (k=1,2 . . . n) component is transmitted by the corresponding BPF1-k, and the transmitted light is multiplexed sequentially and outputted from the port 2-nb and the other wavelength components (noise light components) are reflected by all of the BPFs and outputted from the port 2-nc. When the WDM signal light including wavelengths except for .lambda.1, .lambda.2 . . . .lambda.n is inputted into the port 2-nc, the component of the wavelength .lambda.n (noise light component) is outputted from the port 2-1d and the other wavelength components are outputted from the port 2-1a. And, the optical coupler 6 monitors the output light of the BPF 1 to perceive the levels of the respective wavelength components in the WDM signal light.
    • 在用于波分复用(WDM光)的光学滤波器模块和光学放大装置中,可以独立地设置多个中心波长的多个通过中心波长的各个波长间隔和各个中心波长附近的滤波器特性,从而BPF1 具有不同的通过中心波长λ1,λ2。 。 。 λn和不同的滤波器特性。 而且,当WDM信号光包括波长λ1,λ2时。 。 。 λn被输入到端口2-1a中,λk(k = 1,2 ...)分量被相应的BPF1-k发送,并且发送的光被顺序复用并从端口2-nb输出 并且其他波长分量(噪声光分量)被所有BPF反射并从端口2-nc输出。 当WDM信号光包括除λ1,λ2之外的波长时。 。 。 λn被输入到端口2-nc中,波长λn(噪声光分量)的分量从端口2-1d输出,其它波长分量从端口2-1a输出。 并且,光耦合器6监视BPF 1的输出光以感知WDM信号光中各波长分量的电平。