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    • 36. 发明申请
    • System for administering a combination of therapies to a body lumen
    • 用于将治疗组合施用于体腔的系统
    • US20050222485A1
    • 2005-10-06
    • US11131001
    • 2005-05-16
    • William ShawJames BarryPaul GollMaria Palasis
    • William ShawJames BarryPaul GollMaria Palasis
    • A61B17/22A61B18/02A61B18/04A61K9/00A61K9/22A61N5/10A61N5/00
    • A61K9/0024A61B2017/22051A61B2018/0022A61B2018/0212A61B2018/0262A61B2018/046A61F2/82A61N5/1002
    • The invention provides a system which comprises a medical device that delivers a combination of therapies. These therapies include the administration of radiation, biologically active materials, cryotherapy, and thermotherapy. The present invention is also directed to a method of treating body lumen surfaces using the system of the invention. A system is provided for delivering a biologically active material to a surface of a body lumen being exposed to a radioactive source. In one aspect, the system comprises an implantable medical device which has two opposing ends, each having a surface, and a middle portion. The two opposing ends comprise a biologically active material and the middle portion of the medical device is substantially free of any biologically active material. In another aspect, the system delivers a genetic material to a surface of a body lumen which is exposed to a radioactive source. Another system is provided for treating a surface of a body lumen in which the system comprises an implantable medical device which comprises a biologically active material and a device for applying a therapy source to the parts of the body lumen surface that are in contact with the opposing ends of the medical device. The therapy source may be a cryotherapy source or a thermotherapy source.
    • 本发明提供了一种系统,其包括递送治疗组合的医疗装置。 这些疗法包括辐射,生物活性物质,冷冻疗法和热疗法的管理。 本发明还涉及使用本发明的系统来治疗体腔表面的方法。 提供了一种用于将生物活性材料递送到暴露于放射源的体腔表面的系统。 一方面,该系统包括可植入医疗装置,其具有两个相对的端部,每个端部具有表面和中间部分。 两个相对端包括生物活性材料,并且医疗装置的中间部分基本上不含任何生物活性物质。 在另一方面,系统将遗传物质递送到暴露于放射源的体腔表面。 提供了一种用于处理体腔表面的另一系统,其中该系统包括可植入医疗装置,其包括生物活性材料和用于将治疗源施加到与相对侧接触的体腔表面部分的装置 医疗器械的末端。 治疗源可以是冷冻治疗源或热疗源。