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31. 发明申请

US20120150040A1 APPARATUS, SYSTEM, AND METHOD FOR ADAPTIVELY CONTROLLING A FRAME INTERVAL BETWEEN ULTRASOUND SCANNING FRAMES FOR AN ULTRASOUND ELASTICITY IMAGING SCAN 审中-公开
标题翻译：用于自适应控制用于超声弹性成像扫描的超声波扫描框架之间的帧间隔的装置，系统和方法
公开(公告)号：US20120150040A1
公开(公告)日：2012-06-14
申请号：US13399361
申请日：2012-02-17
申请人： Feng Lin , Christopher Robert Hazard , Mirsaid Seyed-Bolorforosh , Karsten Hiltawsky , Zhe Wu
发明人： Feng Lin , Christopher Robert Hazard , Mirsaid Seyed-Bolorforosh , Karsten Hiltawsky , Zhe Wu
IPC分类号： A61B8/13
CPC分类号： A61B8/485 , A61B8/08 , A61B8/0858 , G01N29/041 , G01N29/043 , G01S7/52085
摘要： An apparatus, system and method for adaptively controlling a frame interval between ultrasound scanning frames of an ultrasound elasticity imaging scan. The system includes a transmitter for transmitting ultrasound beams to a subject during an ultrasound elasticity imaging scan, and a receiver for receiving ultrasound beam echoes from the subject responsive to transmitted ultrasound beams. The system also includes a processor for processing a plurality of the ultrasound beam echoes to determine a strain variation of the tissue undergoing strain, calculating a value for an ultrasound scanning frame interval adapted for imaging the tissue undergoing the determined strain variation, and setting the value of the ultrasound scanning frame interval for acquiring ultrasound elasticity images of the tissue undergoing the determined strain variation.
摘要翻译：一种用于自适应地控制超声波弹性成像扫描的超声扫描帧之间的帧间隔的装置，系统和方法。该系统包括用于在超声波弹性成像扫描期间将超声波束发送到被摄体的发射器，以及用于响应于所发送的超声波束从受检者接收超声波束回波的接收器。该系统还包括处理器，用于处理多个超声波束回波以确定经历应变的组织的应变变化，计算适于对经历所确定的应变变化的组织进行成像的超声扫描帧间隔的值，以及设定值的超声扫描帧间隔，用于获取经历所确定的应变变化的组织的超声弹性图像。

32. 发明授权

US08123692B2 Apparatus, system, and method for adaptively controlling a frame interval between ultrasound scanning frames for an ultrasound elasticity imaging scan 有权
标题翻译：用于自动控制用于超声波弹性成像扫描的超声扫描帧之间的帧间隔的装置，系统和方法
公开(公告)号：US08123692B2
公开(公告)日：2012-02-28
申请号：US11567285
申请日：2006-12-06
申请人： Feng Lin , Christopher Robert Hazard , Mirsaid Seyed-Bolorforosh , Karsten Hiltawsky , Zhe Wu
发明人： Feng Lin , Christopher Robert Hazard , Mirsaid Seyed-Bolorforosh , Karsten Hiltawsky , Zhe Wu
IPC分类号： A61B8/00
CPC分类号： A61B8/485 , A61B8/08 , A61B8/0858 , G01N29/041 , G01N29/043 , G01S7/52085
摘要： An apparatus, system and method for adaptively controlling a frame interval between ultrasound scanning frames of an ultrasound elasticity imaging scan. The system includes a transmitter for transmitting ultrasound beams to a subject during an ultrasound elasticity imaging scan, and a receiver for receiving ultrasound beam echoes from the subject responsive to transmitted ultrasound beams. The system also includes a processor for processing a plurality of the ultrasound beam echoes to determine a strain variation of the tissue undergoing strain, calculating a value for an ultrasound scanning frame interval adapted for imaging the tissue undergoing the determined strain variation, and setting the value of the ultrasound scanning frame interval for acquiring ultrasound elasticity images of the tissue undergoing the determined strain variation.
摘要翻译：一种用于自适应地控制超声波弹性成像扫描的超声扫描帧之间的帧间隔的装置，系统和方法。该系统包括用于在超声波弹性成像扫描期间将超声波束发送到被摄体的发射器，以及用于响应于所发送的超声波束从受检者接收超声波束回波的接收器。该系统还包括处理器，用于处理多个超声波束回波以确定经历应变的组织的应变变化，计算适于对经历所确定的应变变化的组织进行成像的超声扫描帧间隔的值，以及设定值的超声扫描帧间隔，用于获取经历所确定的应变变化的组织的超声弹性图像。

33. 发明申请

US20120046963A1 METHOD, EVALUATION UNIT AND MEDICAL EXPANSION APPARATUS TO DETERMINE AND INVOICE THE USE OF THE MEDICAL EXPANSION APPARATUS 审中-公开
标题翻译：方法，评估单位和医疗扩展装置，用于确定和发送医疗扩展装置的使用
公开(公告)号：US20120046963A1
公开(公告)日：2012-02-23
申请号：US13213242
申请日：2011-08-19
申请人： Christoph Hachmoeller , Karsten Hiltawsky , Sebastian Schmidt , Sabine Schaeffer-Kundler
发明人： Christoph Hachmoeller , Karsten Hiltawsky , Sebastian Schmidt , Sabine Schaeffer-Kundler
IPC分类号： G06Q50/22 , G06Q30/04
CPC分类号： G06F19/328 , G06Q30/04 , G06Q50/22
摘要： In a method to determine and invoice the use of a medical expansion apparatus provided to a user (in particular a service provider) by an owner (in particular a referring physician), the medical expansion apparatus expanding the functionality of a primary medical apparatus, the following steps can be implemented automatically by an evaluation unit. Data describing the usage of the expansion apparatus and/or measurement signals from which the usage data are derived are received from the expansion apparatus and/or the primary apparatus. The usage data are evaluated to create an invoice, in particular a cost calculation. The invoice is sent to the owner and/or the user, in particular to processing devices and/or program means associated with the user and/or the owner.
摘要翻译：在由所有者（特别是转诊医师）确定和发明使用提供给用户（特别是服务提供者）的医疗扩张装置的方法中，扩大主要医疗装置的功能的医疗扩张装置，以下步骤可以由评估单元自动实现。从扩展装置和/或主装置接收描述使用数据导出的扩展装置和/或测量信号的使用的数据。评估使用数据以创建发票，特别是成本计算。发票被发送给所有者和/或用户，特别是处理与用户和/或所有者相关联的设备和/或程序装置。

34. 发明申请

US20110092853A1 INTERVENTION DEVICE FOR COLLECTING BIOLOGICAL MATERIAL AND METHOD FOR THE PRODUCTION THEREOF 审中-公开
标题翻译：用于收集生物材料的干预装置及其生产方法
公开(公告)号：US20110092853A1
公开(公告)日：2011-04-21
申请号：US12996121
申请日：2009-05-29
申请人： Karsten Hiltawsky , Sven Meyburg , Daniel Sickert
发明人： Karsten Hiltawsky , Sven Meyburg , Daniel Sickert
IPC分类号： A61B5/15 , G01N1/28
CPC分类号： G01N33/54366 , A61L29/08 , A61L29/14 , A61L31/08 , A61L31/14
摘要： An intervention device is disclosed for collecting biological material comprises a surface with a coating covering the surface at least in part. In at least one embodiment, capture molecules, by which the biological material can be bound, are immobilized on the coating. The capture molecules are distributed stochastically on the coating.
摘要翻译：公开了用于收集生物材料的干预装置，其包括具有至少部分地覆盖该表面的涂层的表面。在至少一个实施方案中，可以将生物材料结合的捕获分子固定在涂层上。捕获分子随机分布在涂层上。

35. 发明申请

US20110076684A1 APPARATUS AND METHOD FOR ACQUIRING, DETECTING, AND ANALYZING CELLS IN A MICROFLUIDIC SYSTEM 审中-公开
标题翻译：在微流感系统中获取，检测和分析细胞的装置和方法
公开(公告)号：US20110076684A1
公开(公告)日：2011-03-31
申请号：US12880379
申请日：2010-09-13
申请人： Alexander FREY , Karsten Hiltawsky , Daniel Sickert
发明人： Alexander FREY , Karsten Hiltawsky , Daniel Sickert
IPC分类号： C12Q1/68 , C12M1/34 , G01N33/53 , G01N33/574 , C12Q1/02
CPC分类号： G01N33/57492 , B01L3/502761 , B01L2200/0647 , B01L2200/10 , B01L2300/0809 , B01L2300/0877 , B01L2400/0487 , G01N33/56966
摘要： An apparatus is disclosed for acquiring, detecting, and, optionally, analyzing cells in a biological liquid, which apparatus has a microfluidic system. In at least one embodiment, the apparatus includes at least one microfluidic channel having a small cross-section which is completely or partially coated with cell-specific binding molecules and which has no flow obstacles dividing the fluid flow; at least one apparatus for generating a steady and alterable liquid flow through the microfluidic channel, and optionally at least one apparatus for analyzing the genetic information of the cell. In at least one embodiment, the method includes a sample of a biological liquid being conducted through an apparatus defined above at a defined velocity V1 so that cells possibly present in the sample are bound to the cell-specific binding molecules; the sample of the biological liquid and/or a suitable liquid being conducted one or more times through the apparatus at a (different) defined velocity V2 so that nonspecifically bound constituents of the sample are removed; the cells bound to the cell-specific binding molecules being appropriately detected; and optionally the cells bound in the channel being released and the genetic information of the cells being optionally analyzed, with the ratio of the velocities, V1:V2, being in the range from 1:5 to 1:10.
摘要翻译：公开了用于获取，检测和可选地分析生物液体中的细胞的装置，该装置具有微流体系统。在至少一个实施方案中，该装置包括至少一个具有小截面的微流体通道，其完全或部分涂覆有细胞特异性结合分子，并且没有流动障碍物分流流体流动; 用于产生通过微流体通道的稳定和可变的液体流的至少一个装置，以及可选地用于分析细胞的遗传信息的至少一个装置。在至少一个实施方案中，该方法包括以限定的速度V1通过上述设备传导的生物液体的样品，使得可能存在于样品中的细胞与细胞特异性结合分子结合; 生物液体样品和/或合适的液体以（不同的）限定速度V2进行一次或多次穿过设备，从而去除样品的非特异性结合的成分; 与细胞特异性结合分子结合的细胞被适当地检测; 并且可选地，在通道中结合的细胞被释放，并且可选地分析细胞的遗传信息，速度比V1：V2在1:5至1:10的范围内。

36. 发明申请

US20100331833A1 IN-VITRO DEVICE MONITORING DURING MINIMALLY INVASIVE ABLATION THERAPY 审中-公开
标题翻译：在最小的入侵治疗期间的体内装置监测
公开(公告)号：US20100331833A1
公开(公告)日：2010-12-30
申请号：US12492315
申请日：2009-06-26
申请人： Michael Maschke , Gudrun Zahlmann , Sebastian Schmidt , Karsten Hiltawsky
发明人： Michael Maschke , Gudrun Zahlmann , Sebastian Schmidt , Karsten Hiltawsky
IPC分类号： A61B18/02 , A61B18/14 , A61N7/00 , C12Q1/00 , C40B30/00
CPC分类号： G01N33/50 , A61B18/02 , A61B18/14 , A61B18/20 , A61B34/20 , A61B2090/376 , G06F19/3481
摘要： A method and apparatus for monitoring and controlling interventional therapy is described, where the interventional therapy results in the destruction of tissue and the release of chemical markers. When interventional therapy results in destruction of a patient tissue, such as cancerous tissue, a variety of chemical markers may be released into the bloodstream. An in-vitro diagnostic (IVD) device may be used to measure the concentration of an analyte representing a marker and compare the measured concentration with a predetermined set point so as to monitor or control the procedure. The blood for the analysis may be obtained either inter-procedurally or intra-procedurally depending on the promptness of the effect being measured and the speed of measurement.
摘要翻译：描述了用于监测和控制介入治疗的方法和装置，其中介入治疗导致组织的破坏和化学标记的释放。当介入治疗导致患者组织（例如癌组织）的破坏时，各种化学标记物可被释放到血流中。可以使用体外诊断（IVD）装置来测量表示标记物的分析物的浓度，并将测量的浓度与预定设定点进行比较，以便监测或控制程序。用于分析的血液可以通过程序间或程序内获得，这取决于所测量的效果的快速性和测量速度。

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