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31. 发明申请

US20070140288A1 Method and apparatus for accommodating TDM traffic in an ethernet passive optical network 有权
标题翻译：用于在以太网无源光网络中适应TDM业务的方法和装置
公开(公告)号：US20070140288A1
公开(公告)日：2007-06-21
申请号：US11385431
申请日：2006-03-20
申请人： Edward Boyd , Ryan Hirth , Duncan Gray , Sourigno Outsama
发明人： Edward Boyd , Ryan Hirth , Duncan Gray , Sourigno Outsama
IPC分类号： H04B7/212
CPC分类号： H04Q11/0067 , H04Q2011/0064
摘要： One embodiment of the present invention provides a system for accommodating time-division multiplexing (TDM) traffic in an Ethernet passive optical network (EPON). During operation, the system receives data from an upstream TDM channel at a remote node and stores received data in a segmentation buffer. The system encapsulates the data stored in the segmentation buffer into a packet. The system receives a message from the central node granting a TDM transmission window starting at a designated time. The system further communicates the packet to an upstream transmission mechanism within the remote node before the designated time, and transmits to the central node an upstream frame containing the packet at the designated time.
摘要翻译：本发明的一个实施例提供一种用于在以太网无源光网络（EPON）中适应时分复用（TDM）业务的系统。在操作期间，系统从远程节点的上游TDM信道接收数据，并将接收的数据存储在分段缓冲器中。系统将存储在分段缓冲器中的数据封装成一个数据包。系统从指定的时间开始从中央节点接收授予TDM传输窗口的消息。该系统进一步在指定时间之前将分组传送到远程节点内的上行传输机制，并在指定时间向中央节点发送包含分组的上行帧。

32. 发明授权

US07226923B2 Phthalazinone derivatives 失效
标题翻译：酞嗪衍生物
公开(公告)号：US07226923B2
公开(公告)日：2007-06-05
申请号：US11233311
申请日：2005-09-23
申请人： Edward Boyd , Frederick Brookfield , Guy Georges , Bernhard Goller , Sabine Huensch , Petra Rueger , Matthias Rueth , Stefan Scheiblich , Christine Schuell , Wolfgang von der Saal , Justin Warne , Stefan Weigand
发明人： Edward Boyd , Frederick Brookfield , Guy Georges , Bernhard Goller , Sabine Huensch , Petra Rueger , Matthias Rueth , Stefan Scheiblich , Christine Schuell , Wolfgang von der Saal , Justin Warne , Stefan Weigand
IPC分类号： C07D403/12 , C07D403/14 , A61K31/502
CPC分类号： C07D403/12
摘要： Compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates are disclosed. Also disclosed are methods for the preparation of the above-mentioned compounds, pharmaceutical compositions containing them, as well as the use of the above-mentioned compounds in the treatment, control or prevention of illnesses such as cancer.
摘要翻译：公开了式I化合物的药学上可接受的盐，对映体形式，非对映异构体和外消旋体。还公开了制备上述化合物的方法，含有它们的药物组合物，以及上述化合物在治疗，控制或预防诸如癌症等疾病中的用途。

33. 发明申请

US20060287385A1 Small organic molecule regulators of cell proliferation 有权
公开(公告)号：US20060287385A1
公开(公告)日：2006-12-21
申请号：US11412424
申请日：2006-04-27
申请人： Anthony Baxter , Edward Boyd , Maria Frank-Kamenetsky , Oivin Guicherit , Jeffery Porter , Stephen Price , Lee Rubin , John Stibbard
发明人： Anthony Baxter , Edward Boyd , Maria Frank-Kamenetsky , Oivin Guicherit , Jeffery Porter , Stephen Price , Lee Rubin , John Stibbard
IPC分类号： A61K31/381 , C07D333/56 , C07D333/72 , C07D409/02
CPC分类号： A61K31/381 , A61K31/422 , A61K31/44 , A61K31/4436 , A61K31/50 , A61K31/517 , C07D333/70 , C07D409/12 , C07D409/14
摘要： The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a hedgehog agonist, such as the compounds depicted in FIGS. 32 and 33. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal ptc pathway or agonizing smoothened or hedgehog activity.

34. 发明申请

US20060270874A1 Styrylsulfonamides 失效
标题翻译：苯乙烯基磺酰胺
公开(公告)号：US20060270874A1
公开(公告)日：2006-11-30
申请号：US11414042
申请日：2006-04-28
申请人： Edward Boyd , Frederick Brookfield , Jonathan Gridley , Matthias Koerner , Manfred Kubbies , Raymond Lau , Ulrike Reiff , Georg Tiefenthaler , Wolfgang von der Saal , Timothy Woodcock
发明人： Edward Boyd , Frederick Brookfield , Jonathan Gridley , Matthias Koerner , Manfred Kubbies , Raymond Lau , Ulrike Reiff , Georg Tiefenthaler , Wolfgang von der Saal , Timothy Woodcock
IPC分类号： C07C311/45
CPC分类号： C07C311/51
摘要： The present invention relates to the compounds of formula I: their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.
摘要翻译：本发明涉及式I化合物：其药学上可接受的盐或酯，对映体形式，非对映异构体和外消旋物，上述化合物的制备，含有它们的药物组合物及其制备，以及这些化合物在控制或预防癌症等疾病。

35. 发明申请

US20050256151A1 Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them 有权
公开(公告)号：US20050256151A1
公开(公告)日：2005-11-17
申请号：US11020793
申请日：2004-12-23
申请人： Barbara Salom , Matteo D'Anello , Maria Brasca , Patrizia Giordano , Katia Martina , Francesco Angelucci , Frederick Brookfield , William Trigg , Edward Boyd , Jonathan Larard
发明人： Barbara Salom , Matteo D'Anello , Maria Brasca , Patrizia Giordano , Katia Martina , Francesco Angelucci , Frederick Brookfield , William Trigg , Edward Boyd , Jonathan Larard
IPC分类号： C07D471/04 , G01N33/53 , A61K31/4745 , C07D471/02
CPC分类号： C07D471/04
摘要： Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.

36. 发明申请

US20050243837A1 Method and apparatus for L3-aware switching in an ethernet passive optical network 有权
标题翻译：以太网无源光网络中L3感知交换的方法和装置
公开(公告)号：US20050243837A1
公开(公告)日：2005-11-03
申请号：US11115753
申请日：2005-04-26
申请人： Edward Boyd , Russell Smith
发明人： Edward Boyd , Russell Smith
IPC分类号： H04L12/28 , H04L12/56 , H04Q11/00
CPC分类号： H04L45/00 , H04L45/502 , H04Q11/0066 , H04Q11/0067 , H04Q11/0071
摘要： One embodiment of the present invention provides a system that performs layer 3 (L3) aware switching in an Ethernet passive optical network (EPON) which includes a central node and at least one remote node. During operation, the system maintains a set of mapping information which indicates a correspondence relationship between a logical link identifier of a remote node, a medium access control (MAC) address for a subscriber coupled to the remote node, and an IP address for the subscriber. Upon receiving a packet which contains an IP address, the system selectively attaches a proper logical link identifier to the packet based on the mapping information and the IP address contained in the packet, thereby allowing only one proper remote node to receive the packet.
摘要翻译：本发明的一个实施例提供一种在包括中央节点和至少一个远程节点的以太网无源光网络（EPON）中执行层3（L3）感知交换的系统。在操作期间，系统维护一组映射信息，其指示远程节点的逻辑链路标识符，耦合到远程节点的用户的介质访问控制（MAC）地址和用户的IP地址之间的对应关系。在接收到包含IP地址的分组时，系统基于分组中包含的映射信息和IP地址，选择性地将附加适当的逻辑链路标识符附加到分组，从而仅允许一个适当的远程节点接收分组。

37. 发明申请

US20050207450A1 Method and apparatus for remote network management over Ethernet connections 有权
标题翻译：通过以太网连接进行远程网络管理的方法和装置
公开(公告)号：US20050207450A1
公开(公告)日：2005-09-22
申请号：US10805088
申请日：2004-03-18
申请人： Hung Nguyen , Edward Boyd
发明人： Hung Nguyen , Edward Boyd
IPC分类号： H04L12/24 , H04J3/00
CPC分类号： H04L41/00
摘要： One embodiment of the present invention provides a system that performs remote network management over an Ethernet connection between a local node and a remote node, wherein the Ethernet connection uses x-bit/y-bit (xB/yB) encoding. During operation, the system accepts a local Ethernet bit stream containing x-bit words at the local node. The system forms a second bit stream which carries network management information. The system then selectively encodes the x-bit words from the local Ethernet bit stream into y-bit words according to the bits from the second bit stream, thereby forming a third bit stream comprising y-bit words, wherein the third bit stream carries both information from the Ethernet bit stream and information from the second bit stream. The system then transmits the third bit stream on a physical medium from the local node to the remote node.
摘要翻译：本发明的一个实施例提供一种通过本地节点和远程节点之间的以太网连接执行远程网络管理的系统，其中以太网连接使用x位/ y位（xB / yB）编码。在操作期间，系统接收本地节点上包含x位字的本地以太网位流。系统形成携带网络管理信息的第二比特流。然后，该系统根据来自第二比特流的比特，将本地以太网比特流中的x比特字选择性地编码为y比特字，从而形成包括y比特字的第三比特流，其中第三比特流携带两者来自以太网比特流的信息和来自第二比特流的信息。然后，该系统将物理介质上的第三比特流从本地节点发送到远程节点。

38. 发明申请

US20050070578A1 Small organic molecule regulators of cell proliferation 审中-公开
标题翻译：细胞增殖的小有机分子调节剂
公开(公告)号：US20050070578A1
公开(公告)日：2005-03-31
申请号：US10491225
申请日：2002-09-18
申请人： Anthony Baxter , Edward Boyd , Maria Frank-Kamenetsky , Jeffery Porter , Stephen Price , Lee Rubin , John Stibbard
发明人： Anthony Baxter , Edward Boyd , Maria Frank-Kamenetsky , Jeffery Porter , Stephen Price , Lee Rubin , John Stibbard
IPC分类号： A61K31/381 , A61K31/422 , A61K31/44 , A61K31/4436 , A61K31/50 , A61K31/517 , C07D333/70 , C07D409/12 , C07D409/14 , A61K31/4025 , C07D333/56 , C07D49/02
CPC分类号： C07D409/12 , A61K31/381 , A61K31/422 , A61K31/44 , A61K31/4436 , A61K31/50 , A61K31/517 , C07D333/70 , C07D409/14
摘要： The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a hedgehog agonist, such as the compounds depicted in FIGS. 32 and 33. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal ptc pathway or agonizing smoothened or hedgehog activity.
摘要翻译：本发明提供用于调节细胞或组织中的增殖或分化的可用方法和试剂，包括使细胞与刺猬激动剂接触，所述刺猬激动剂例如图1和图2所示的化合物。在某些实施方案中，可以使用方法和试剂来校正或抑制异常或不想要的生长状态，例如通过拮抗正常的ptc途径或激动平滑的或刺猬活性。

39. 发明申请

US20050014796A1 Mediators of hedgehog signaling pathways, compositions and uses related thereto 审中-公开
标题翻译：刺猬信号通路的调解者，与之相关的组合物和用途
公开(公告)号：US20050014796A1
公开(公告)日：2005-01-20
申请号：US10732669
申请日：2003-12-09
申请人： Anthony Baxter , Edward Boyd , Oivin Guicherit , Jeffrey Porter , Stephen Price , Lee Rubin
发明人： Anthony Baxter , Edward Boyd , Oivin Guicherit , Jeffrey Porter , Stephen Price , Lee Rubin
IPC分类号： A61K31/381 , A61K31/422 , A61K31/44 , A61K31/50 , A61K31/517 , C07D333/70 , C07D409/12 , C07D409/14 , A61K31/444 , A61K31/137 , A61K31/40
CPC分类号： C07D409/12 , A61K31/381 , A61K31/422 , A61K31/44 , A61K31/50 , A61K31/517 , C07D333/70 , C07D409/14
摘要： The present invention makes available methods and reagents for inducing activation of a hedgehog pathway in a cell or tissue comprising contacting the cell with a hedgehog agonist, such as a small molecule, in a sufficient amount to achieve a therapeutic result. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal ptc pathway or agonizing smoothened or hedgehog activity.
摘要翻译：本发明提供用于诱导细胞或组织中刺猬蛋白通路激活的可用方法和试剂，包括以足够的量使细胞与刺猬激动剂如小分子接触以获得治疗结果。在某些实施方案中，可以使用所述方法和试剂来校正或抑制异常或不想要的生长状态，例如通过拮抗正常的ptc途径或激动平滑的或刺猬活性。

40. 外观设计

USD447977S1 Portion of a watch housing 失效
公开(公告)号：USD447977S1
公开(公告)日：2001-09-18
申请号：US29138929
申请日：2001-03-22
申请人： Sung-Ho Joe Tan , Edward Boyd
设计人： Sung-Ho Joe Tan , Edward Boyd

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