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31. 发明申请

US20120128722A1 Novel Monensin Derivatives for the Treatment and Prevention of Protozoal Infections 有权
标题翻译：用于治疗和预防原生动物感染的新型莫能菌素衍生物
公开(公告)号：US20120128722A1
公开(公告)日：2012-05-24
申请号：US13297367
申请日：2011-11-16
申请人： Jean Delaveau , Emile Vialle , Marc Lemaire , Stephane Pellet-Rostaing , Bruno Andrioletti
发明人： Jean Delaveau , Emile Vialle , Marc Lemaire , Stephane Pellet-Rostaing , Bruno Andrioletti
IPC分类号： A61K31/35 , C07D493/22 , A61K31/366 , A61P33/06 , A61K39/002 , A61P37/04 , A61P33/02 , A61P1/12 , C07D493/10 , A61K31/365
CPC分类号： C07D493/10 , C07D519/00
摘要： This invention relates to novel polyether ionophores, formulations comprising same, and to methods of making and using these compounds and formulations for the treatment and/or prevention of parasitic infection in animals and humans. These compounds exhibit improved safety profiles and/or efficacies as compared to parent compounds.
摘要翻译：本发明涉及新型聚醚离子载体，包含其的制剂，以及制备和使用这些化合物和制剂用于治疗和/或预防动物和人类寄生虫感染的方法。与母体化合物相比，这些化合物表现出改善的安全性和/或功效。

32. 发明申请

US20090252816A1 Inhalable Gaseous Medicament Based On Xenon And Nitrous Oxide 审中-公开
标题翻译：基于氙气和一氧化二氮的可吸入气体药物
公开(公告)号：US20090252816A1
公开(公告)日：2009-10-08
申请号：US12417087
申请日：2009-04-02
申请人： Jacques Abraini , Marc Lemaire
发明人： Jacques Abraini , Marc Lemaire
IPC分类号： A61K33/00
CPC分类号： A61K33/00 , A61K2300/00
摘要： The invention concerns the use of a gaseous mixture containing gas xenon and gas nitrous oxide, and advantageously oxygen, for making all or part of an inhalable medicine for preventing or treating neurointoxication in a human. The xenon/nitrous oxide mixture of the invention acts on one or more cerebral receptors to reduce the release and/or the effects of dopamine, glutamate, serotonin, taurin, GABA, noradrenaline and/or any other neurotransmitter. The proportion by volume of xenon of the mixture ranges between 5 and 45%, and the proportion by volume of nitrous oxide ranges between 10 and 50%, the balance is preferably oxygen.
摘要翻译：本发明涉及使用含有气体氙气和一氧化二氮气体以及有利地为氧气的气体混合物，用于制备用于预防或治疗人类神经毒素的全部或部分可吸入药物。本发明的氙/一氧化二氮混合物作用于一种或多种脑受体，以减少多巴胺，谷氨酸，血清素，牛磺酸，GABA，去甲肾上腺素和/或任何其他神经递质的释放和/或作用。混合物的氙的体积比例为5〜45％，一氧化二氮的体积比为10〜50％，余量优选为氧。

33. 发明申请

US20060131213A1 Method for the denitrization of hydrocarbon charges in the presence of a polymeric mass 审中-公开
标题翻译：在聚合物存在下使烃电荷脱硝的方法
公开(公告)号：US20060131213A1
公开(公告)日：2006-06-22
申请号：US10508085
申请日：2003-03-18
申请人： Marc Lemaire , Mathieu Macaud , Alain Favre-Reguillon , Emmanuelle Schulz , Marc Sevignon , Roben Loutaty
发明人： Marc Lemaire , Mathieu Macaud , Alain Favre-Reguillon , Emmanuelle Schulz , Marc Sevignon , Roben Loutaty
IPC分类号： C10G49/22
CPC分类号： C10G25/003
摘要： A process for denitrogenation of hydrocarbonated compounds containing basic and/or neutral nitrogenous hydrocarbonated compounds characterized by the fact that the hydrocarbonated compounds are placed in contact with a polymeric material including at least one polymer P obtained from at least one non-styrenic monomer A with at least one polar function generating hydrogen bonds with the nitrogenous hydrocarbonated compounds.
摘要翻译：一种脱氮含有碱性和/或中性含氮烃化合物的烃化合物的方法，其特征在于将烃化合物与包含至少一种由至少一种非苯乙烯类单体A获得的聚合物P的聚合物材料接触，至少一个与含氮烃化合物产生氢键的极性官能团。

34. 发明申请

US20050180926A1 Inhalable aerosol medicament for the treatment or prevention of pain 审中-公开
标题翻译：用于治疗或预防疼痛的可吸入气雾剂
公开(公告)号：US20050180926A1
公开(公告)日：2005-08-18
申请号：US11107809
申请日：2005-04-18
申请人： Laurent Lecourt , Franck Lescure , Marc Lemaire
发明人： Laurent Lecourt , Franck Lescure , Marc Lemaire
IPC分类号： A61K9/00 , A61K9/10 , A61K9/12 , A61K9/72 , A61K31/167 , A61K31/192 , A61K31/4355 , A61K31/573 , A61K31/616 , A61K33/00 , A61K45/06 , A61M11/00 , A61P23/00 , A61P29/00 , A61L9/04 , A61K9/14 , A61K31/60
CPC分类号： A61K9/008 , A61K9/0073 , A61K9/124 , A61K33/00 , A61K45/06 , A61K2300/00
摘要： The invention concerns the use of at least one gas in combination with at least one active product for manufacturing an inhalable medicament or part of an inhalable medicament intended for the treatment or prevention of pain in humans or animals. The gas is chosen from among helim, oxygen, nitrogen, xenon, hydrogen, carbon monoxide (CO), carbon dioxide (CO2), argon, krypton, nitrogen monoxide (NO), nitrogen protoxide (N2O), carbonated hydrocarbons, fluorocarbons and mixtures of several of these gases. The active product is chosen from among paracetamol, acetylsalicylic acid, arylcarboxylic acid, corticosteroids, mineralosteroids, non-steoroidal anti-inflammatory drugs and their derivatives, codeine and its derivatives, morphine and morphine mimetics.
摘要翻译：本发明涉及至少一种气体与至少一种活性产品的组合用于制造用于治疗或预防人或动物疼痛的可吸入药物或可吸入药物的一部分。气体选自直升机，氧气，氮气，氙气，氢气，一氧化碳（CO），二氧化碳（CO 2/2），氩气，氪气，一氧化氮（NO），氮氧化氮（N O 2），碳酸烃，碳氟化合物和这些气体中的几种的混合物。活性产物选自对乙酰氨基酚，乙酰水杨酸，芳基羧酸，皮质类固醇，类固醇，非甾体抗炎药及其衍生物，可待因及其衍生物，吗啡和吗啡模拟物。

35. 发明授权

US5268448A Conducting polymers derived from fluorinated thiophenes 失效
标题翻译：衍生自氟化噻吩的聚合物的导电
公开(公告)号：US5268448A
公开(公告)日：1993-12-07
申请号：US899130
申请日：1992-06-16
申请人： Werner Buechner , Marc Lemaire , Jean Roncali , Robert Garreau , Francis Garnier , Etienne Hannecart
发明人： Werner Buechner , Marc Lemaire , Jean Roncali , Robert Garreau , Francis Garnier , Etienne Hannecart
IPC分类号： C07D333/12 , C08G61/12 , H01B1/12 , H01M4/60 , C08G75/00
CPC分类号： C08G61/126 , C07D333/12 , H01B1/127 , H01M4/60
摘要： Substituted thiophenes of general formula: ##STR1## in which: R represents hydrogen atom or an aliphatic group containing from 1 to 4 carbon atoms,X and Z may be identical or different and represent a hydrogen atom or a fluorine atom,Y represents an at least partially fluorinated aliphatic or aromatic group,m represents an integer equal to or greater than 1, andn represents an integer such that 0.ltoreq.n.ltoreq.12.The invention also relates to the electrically conducting polymers containing recurring units derived from monomers chosen from the substituted thiophenes.
摘要翻译：具有以下通式的取代的噻吩：其中：R表示氢原子或含有1至4个碳原子的脂族基团，X和Z可以相同或不同，表示氢原子或氟原子，Y表示最少部分氟化的脂族或芳族基团，m表示等于或大于1的整数，n表示0≤n≤12的整数。本发明还涉及含有衍生自选自取代的噻吩的单体的重复单元的导电聚合物。

36. 发明授权

US5132049A Substituted thiophenes, conducting polymers derived from these thiophenes, process for obtaining them and devices containing these polymers 失效
标题翻译：取代的THIOPHENES，从这些THIOPHENES衍生的导电聚合物，获得它们的方法和包含这些聚合物的装置
公开(公告)号：US5132049A
公开(公告)日：1992-07-21
申请号：US444885
申请日：1989-12-04
申请人： Robert Garreau , Jean Roncali , Marc Lemaire , Hafsa Korri , Francis Garnier , Etienne Hannecart
发明人： Robert Garreau , Jean Roncali , Marc Lemaire , Hafsa Korri , Francis Garnier , Etienne Hannecart
IPC分类号： C07D333/16 , C07D333/28 , C07D333/32 , C08G61/10 , C08G61/12 , C25B3/02 , C25B3/10 , C25B11/04 , H01B1/12 , H01M4/60 , H01M4/62
CPC分类号： C08G61/126 , C07D333/16 , H01B1/127 , H01M4/60
摘要： Substituted thiophenes of the general formula: ##STR1## in which: R represents a hydrogen atom, a halogen atom or an aliphatic group containing from 1 to 4 carbon atoms,X represents a hydrogen atom or a fluorine atom,Y represents an at least partially fluorinated aliphatic or aromatic group,m represents an integer equal to or greater than 2, andn represents an integer such that 0.ltoreq.n.ltoreq.7.The invention also relates to the electrically conducting polymers containing recurring units derived from monomers chosen from the substituted thiophenes.
摘要翻译：取代的以下通式的噻吩：其中：R表示氢原子，卤素原子或含有1至4个碳原子的脂族基团，X表示氢原子或氟原子，Y表示至少部分氟化脂族或芳族基团，m表示等于或大于2的整数，n表示0≤n≤7的整数。本发明还涉及含有衍生自选自取代的噻吩的单体的重复单元的导电聚合物。

37. 发明授权

US4909959A Conductive polymers derived from 3-alkylthiophenes, a process for manufacturing them and electroconductive devices containing them 失效
标题翻译：衍生自3-烷基噻吩的导电聚合物，其制备方法和含有它们的导电装置
公开(公告)号：US4909959A
公开(公告)日：1990-03-20
申请号：US32637
申请日：1987-04-01
申请人： Marc Lemaire , Jean Roncali , Robert Garreau , Francis Garnier , Etienne Hannecart
发明人： Marc Lemaire , Jean Roncali , Robert Garreau , Francis Garnier , Etienne Hannecart
IPC分类号： C08G61/10 , C08G61/12 , G02F1/15 , H01B1/12 , H01M4/60
CPC分类号： H01B1/127 , C08G61/126 , H01M4/60
摘要： The subject of the invention is mainly an electrically conductive polymer containing repeated units derived from 3-alkythiophenes in which the alkyl substituent contains from six to nine carbon atoms.The invention also relates to a process for manufacturing these polymers and to electroconductive devices containing them.
摘要翻译：本发明的主题主要是含有衍生自3-链噻吩的重复单元的导电聚合物，其中烷基取代基含有6至9个碳原子。本发明还涉及制造这些聚合物的方法和含有这些聚合物的导电装置。

38. 发明授权

US4567952A Process and apparatus for locking and releasing of a drilling shaft with essentially vertical axis 失效
标题翻译：具有基本垂直轴线的钻井轴的锁定和释放的过程和装置
公开(公告)号：US4567952A
公开(公告)日：1986-02-04
申请号：US489301
申请日：1983-04-28
申请人： Marc Lemaire , Roland Le Roc'h
发明人： Marc Lemaire , Roland Le Roc'h
IPC分类号： E21B19/10 , E21B19/16 , E21B3/00
CPC分类号： E21B19/16 , E21B19/10
摘要： Apparatus and method for the locking and releasing of a train of drilling shafts having an essentially vertical axis employ wedges adapted to penetrate an opening in a rotation table of a wellhole in order to lock upon a shaft projecting from the opening while another shaft is screwed to or unscrewed from the upper end of the first-mentioned shaft. The wedges have a tapered external shape complementary to the shape of the opening and an internal shape complementary to the external shape of the shafts. Each wedge is individually attached to an associated arm connected to a vertically movable plate by means of an articulation and a jack that applies the wedge to a shaft. The attachment of the wedges to the arms has sufficient freedom to permit the wedges to engage a shaft and center the shaft between the wedges automatically before the wedges are lowered into the opening of the rotation table to lock the engaged shaft therebetween.
摘要翻译：用于锁定和释放具有基本竖直轴线的钻杆串的装置和方法采用适于穿透井眼的旋转台中的开口的楔形件，以便锁定在从开口突出的轴上，而另一轴被拧到或从第一个提到的轴的上端旋下。楔形件具有与开口形状互补的锥形外形和与轴的外部形状互补的内部形状。每个楔子通过铰接和将楔子施加到轴上的千斤顶单独地附接到连接到可垂直移动的板的相关臂上。将楔形物附接到臂上具有足够的自由度，以允许楔形物接合轴并在楔形物下降到旋转台的开口之前自动地将轴中心在楔块之间，以将接合的轴锁定在其间。

39. 发明授权

US4545269A Machine to apply a screwing or unscrewing torque 失效
标题翻译：机器应用螺丝拧紧扭矩
公开(公告)号：US4545269A
公开(公告)日：1985-10-08
申请号：US489459
申请日：1983-04-28
申请人： Marc Lemaire , Roland Le Roc'h
发明人： Marc Lemaire , Roland Le Roc'h
IPC分类号： E21B3/04 , E21B19/16
CPC分类号： E21B19/16
摘要： A machine to apply screwing and unscrewing torque to successive drilling shafts employs upper and lower claws, one of which is fixed and the other of which rotates through a limited angular range. Each claw comprises a pair of right-angle branches extending oppositely from a base and terminating in spaced relation to provide a permanent opening at one side of the claw opposite to the base. Each claw has a jaw comprising three gripping elements positioned essentially at the vertices of an equilateral triangle, one gripping element being fixed to the base and the other gripping elements being movably mounted on the branches at opposite sides of the opening. One claw comprises a pair of parts relatively movable vertically to form a viewing opening when the machine is not applying torque.
摘要翻译：用于将螺丝拧松扭矩施加到连续钻孔的机器采用上下爪，其中一个固定，另一个在有限的角度范围内旋转。每个爪包括一对直角分支，其从基部相对地延伸并以间隔开的方式终止，以在与基部相对的爪的一侧提供永久的开口。每个爪具有夹爪，其包括基本上位于等边三角形的顶点处的三个夹紧元件，一个夹紧元件固定到基座，而另一个夹持元件可移动地安装在开口的相对侧上的分支上。一个爪包括一对垂直相对移动的部件，以在机器不施加扭矩时形成观察开口。

40. 发明申请

US20160326084A1 Process For Preparing A Carboxylic Acid 有权
标题翻译：制备羧酸的方法
公开(公告)号：US20160326084A1
公开(公告)日：2016-11-10
申请号：US15107855
申请日：2014-12-24
申请人： Marc LEMAIRE , Estelle METAY , Marc SUTTER , Yann RAOUL , Eric DA SILVA , Sophie SAMBOU , Philippe BLACH , Avril , Oleon SA , Université Claude Bernard Lyon 1 , Centre National de la Recherche Scientifique (CNRS)
发明人： Marc Lemaire , Estelle Metay , Marc Sutter , Yann Raoul , Eric Da Silva , Sophie Sambou , Philippe Blach
IPC分类号： C07C51/245 , C07C67/333 , C07C51/25 , C07C51/353 , C08K5/101 , C08K5/11 , C08K5/09 , C08K5/092 , C09J11/06 , A61K8/37 , A61K8/36 , A61K8/362 , A01N37/02 , B01J21/08 , B01J21/04 , B01J37/08 , C10M129/42 , C10M129/40 , A23L33/10 , C07C67/30
CPC分类号： C07C51/245 , A01N37/02 , A23L33/10 , A23V2002/00 , A61K8/361 , A61K8/362 , A61K8/37 , B01J21/04 , B01J21/08 , B01J37/08 , C07C51/23 , C07C51/25 , C07C51/353 , C07C67/30 , C07C67/333 , C08K5/09 , C08K5/092 , C08K5/101 , C08K5/11 , C09J11/06 , C10M129/40 , C10M129/42 , C10M2207/126 , C10M2207/127 , C07C53/126 , C07C69/48
摘要： A process for preparing a carboxylic acid, including a step of bringing at least one vicinal diol or at least one vicinal polyol into contact with an atmosphere including oxygen, and a catalyst, and in the absence of additional solvent.
摘要翻译：一种制备羧酸的方法，包括使至少一种邻位二醇或至少一个邻位多元醇与包含氧气和催化剂的气氛以及在不存在另外的溶剂的情况下接触的步骤。

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