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31. 发明申请

US20110182991A1 METHOD FOR IMPROVED FIBRIN SEALING 有权
标题翻译：改进纤维素密封方法
公开(公告)号：US20110182991A1
公开(公告)日：2011-07-28
申请号：US13015999
申请日：2011-01-28
申请人： Erez Ilan , Kfir Regev , Israel Nur
发明人： Erez Ilan , Kfir Regev , Israel Nur
IPC分类号： A61K9/14 , A61K38/48 , A61P17/02 , A61P17/00
CPC分类号： A61L24/043 , A61L24/0015 , A61L24/0042 , A61L24/10 , A61L24/106 , A61L2300/252 , A61L2300/254 , A61L2300/418 , A61L2300/45 , A61L2300/61 , A61L2400/04 , B65D81/32
摘要： The present invention relates to a fibrin matrix, its preparation and use for effectively sealing a defect in a mucosa or other moist tissue.
摘要翻译：本发明涉及一种纤维蛋白基质，其制备和用途，用于有效地密封粘膜或其它潮湿组织中的缺陷。

32. 发明申请

US20100310524A1 Compositions Suitable for Treatment of Spinal Disease, Disorder or Condition 有权
标题翻译：适用于治疗脊髓疾病，疾病或病症的组合物
公开(公告)号：US20100310524A1
公开(公告)日：2010-12-09
申请号：US12675234
申请日：2008-08-29
申请人： Edna Bechor , Liliana Bar , Israel Nur
发明人： Edna Bechor , Liliana Bar , Israel Nur
IPC分类号： A61K35/16 , C12N5/02 , A61K38/43 , A61P19/00
CPC分类号： A61K35/16 , A61K35/545 , A61K38/1709 , A61K38/363 , A61L27/3616 , A61L27/3804 , A61L27/3856 , A61L27/3878 , A61L2430/38 , C12N5/0655 , C12N2500/84 , A61K2300/00
摘要： The invention relates to the use of viral inactivated-plasma cryoprecipitate concentrate (VIPCC) comprising a suitable fibronectin/fibrinogen ratio for treating a spine disease, disorder or condition such as intervertebral disc degeneration.
摘要翻译：本发明涉及包含适当的纤连蛋白/纤维蛋白原比例的病毒灭活血浆冷沉淀物浓缩物（VIPCC）用于治疗脊椎疾病，病症或病症如椎间盘退变的用途。

33. 发明申请

US20100203033A1 Kits, formulations and solutions having enzymatically- permissive amounts of visualization agents and uses thereof 审中-公开
标题翻译：具有酶允许量的可视化试剂的试剂盒，制剂和溶液及其用途
公开(公告)号：US20100203033A1
公开(公告)日：2010-08-12
申请号：US12665810
申请日：2008-07-01
申请人： Israel Nur , Roberto Meidler , Liliana Bar
发明人： Israel Nur , Roberto Meidler , Liliana Bar
IPC分类号： A61L24/10
CPC分类号： A61L24/106 , A61L24/043 , A61L24/108 , A61L31/046 , C08L89/00
摘要： The invention relates to a proteolytic enzyme which is capable of forming fibrin when it reacts with fibrinogen, a fibrin-glue kit and a fibrin-glue formulation comprising an enzymatically-permissive concentration of a visualization agent and to their use in methods for prevention and/or reduction of adhesions and/or methods for promotion of blood coagulation sealing or filling body surfaces.
摘要翻译：本发明涉及当与纤维蛋白原反应时能够形成纤维蛋白的蛋白水解酶，纤维蛋白胶试剂盒和包含酶允许浓度的可视化试剂的纤维蛋白胶制剂，以及它们在预防和/ 或减少用于促进血液凝固密封或填充体表面的粘合和/或方法。

34. 发明申请

US20060257458A1 Reinforced absorbable multilayered hemostatis wound dressing 有权
标题翻译：增强吸收性多层切割伤口敷料
公开(公告)号：US20060257458A1
公开(公告)日：2006-11-16
申请号：US11400849
申请日：2006-04-10
申请人： Anne Gorman , Sanyog Pendharkar , Guanghui Zhang , Liliana Bar , Israel Nur , Roberto Meidler
发明人： Anne Gorman , Sanyog Pendharkar , Guanghui Zhang , Liliana Bar , Israel Nur , Roberto Meidler
IPC分类号： A61L15/00
CPC分类号： A61L15/26 , A61F13/00029 , A61L15/28 , A61L15/32 , A61L15/44 , A61L15/64 , A61L2300/418 , A61L2300/608 , A61L2400/04 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B23/02 , B32B23/10 , B32B27/36 , B32B2250/20 , B32B2262/0276 , B32B2262/04 , B32B2262/06 , B32B2262/062 , B32B2307/726 , B32B2556/00 , Y10T442/2525 , C08L67/04
摘要： The present invention is directed to a reinforced absorbable multilayered hemostatic wound dressing comprising a first absorbable nonwoven fabric, a second absorbable woven or knitted fabric, thrombin and/or fibrinogen.
摘要翻译：本发明涉及包含第一可吸收无纺布，第二可吸收编织物或针织物，凝血酶和/或纤维蛋白原的增强可吸收多层止血伤口敷料。

35. 发明申请

US20060088589A1 Reinforced absorbable multilayered hemostatic wound dressing 审中-公开
标题翻译：增强吸收性多层止血伤口敷料
公开(公告)号：US20060088589A1
公开(公告)日：2006-04-27
申请号：US11252175
申请日：2005-10-17
申请人： Anne Gorman , Sanyog Pendharkar , Guanghui Zhang , Lillian Bar , Israel Nur , Orgad Laub
发明人： Anne Gorman , Sanyog Pendharkar , Guanghui Zhang , Lillian Bar , Israel Nur , Orgad Laub
IPC分类号： A61K9/66
CPC分类号： A61L15/26 , A61F13/00029 , A61L15/28 , A61L15/32 , A61L15/44 , A61L15/64 , A61L2300/418 , A61L2300/608 , A61L2400/04 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B23/02 , B32B23/10 , B32B27/36 , B32B2250/20 , B32B2262/0276 , B32B2262/04 , B32B2262/06 , B32B2262/062 , B32B2307/726 , B32B2556/00 , Y10T442/2525 , C08L67/04
摘要： The present invention is directed to a reinforced absorbable multilayered hemostatic wound dressing comprising a first absorbable nonwoven fabric, a second absorbable woven or knitted fabric, thrombin and fibrinogen.
摘要翻译：本发明涉及包含第一可吸收无纺布，第二可吸收编织物或针织物，凝血酶和纤维蛋白原的增强可吸收多层止血伤口敷料。

36. 发明授权

US09439997B2 Reinforced absorbable multilayered hemostatis wound dressing 有权
公开(公告)号：US09439997B2
公开(公告)日：2016-09-13
申请号：US11400849
申请日：2006-04-10
申请人： Anne Jessica Gorman , Sanyog Manohar Pendharkar , Guanghui Zhang , Liliana Bar , Israel Nur , Roberto Meidler
发明人： Anne Jessica Gorman , Sanyog Manohar Pendharkar , Guanghui Zhang , Liliana Bar , Israel Nur , Roberto Meidler
IPC分类号： A61L15/00 , A61L15/26 , A61L15/28 , A61L15/32 , A61L15/44 , A61L15/64 , B32B5/02 , B32B5/26 , B32B23/02 , B32B23/10 , B32B27/36
CPC分类号： A61L15/26 , A61F13/00029 , A61L15/28 , A61L15/32 , A61L15/44 , A61L15/64 , A61L2300/418 , A61L2300/608 , A61L2400/04 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B23/02 , B32B23/10 , B32B27/36 , B32B2250/20 , B32B2262/0276 , B32B2262/04 , B32B2262/06 , B32B2262/062 , B32B2307/726 , B32B2556/00 , Y10T442/2525 , C08L67/04
摘要： The present invention is directed to a reinforced absorbable multilayered hemostatic wound dressing comprising a first absorbable nonwoven fabric, a second absorbable woven or knitted fabric, thrombin and/or fibrinogen.

37. 发明授权

US09125906B2 Treatment of peripheral vascular disease using umbilical cord tissue-derived cells 有权
标题翻译：使用脐带组织来源的细胞治疗外周血管疾病
公开(公告)号：US09125906B2
公开(公告)日：2015-09-08
申请号：US13206913
申请日：2011-08-10
申请人： Charito S. Buensuceso , Anthony J. Kihm , Sridevi Dhanaraj , Roee Atlas , Israel Nur , Roberto Meidler , Liliana Bar
发明人： Charito S. Buensuceso , Anthony J. Kihm , Sridevi Dhanaraj , Roee Atlas , Israel Nur , Roberto Meidler , Liliana Bar
IPC分类号： A61K35/51 , A61K45/00 , A61K38/48 , A61K45/06 , A61L27/38 , C12N5/073 , A61K38/36
CPC分类号： A61K35/51 , A61K35/34 , A61K35/44 , A61K35/545 , A61K38/363 , A61K38/4833 , A61K45/06 , A61L27/3834 , A61L27/3839 , A61L27/3886 , A61L27/3895 , C12N5/0605 , C12N2510/00 , A61K2300/00 , A61K35/15
摘要： Compositions and methods of using cells derived from umbilical cord tissue, to stimulate and support angiogenesis, to improve blood flow, to regenerate, repair, and improve skeletal muscle damaged by a peripheral ischemic event, and to protect skeletal muscle from ischemic damage in peripheral vascular disease patients are disclosed. In particular, methods of treating a patient having a peripheral vascular disease with umbilical derived cells and fibrin glue are disclosed.
摘要翻译：使用衍生自脐带组织的细胞刺激和支持血管生成，改善血流量，再生，修复和改善由外周缺血事件损伤的骨骼肌的组合物和方法，以及保护骨骼肌免受外周血管中的缺血性损伤疾病患者被披露。特别地，公开了用脐带血细胞和纤维蛋白胶治疗患有外周血管疾病的患者的方法。

38. 发明授权

US08857694B2 Staple cartridge loading assembly 有权
标题翻译：装钉盒装载装置
公开(公告)号：US08857694B2
公开(公告)日：2014-10-14
申请号：US13097869
申请日：2011-04-29
申请人： Frederick E. Shelton, IV , Chester O. Baxter, III , Taylor W. Aronhalt , Venkataramanan Mandakolathur Vasudevan , Israel Nur , John V. Hunt , Geoffrey C. Hueil , Gregory J. Fanuele
发明人： Frederick E. Shelton, IV , Chester O. Baxter, III , Taylor W. Aronhalt , Venkataramanan Mandakolathur Vasudevan , Israel Nur , John V. Hunt , Geoffrey C. Hueil , Gregory J. Fanuele
IPC分类号： A61B17/10 , A61B17/04
CPC分类号： A61B17/105 , A61B17/00234 , A61B17/00491 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/07292 , A61B17/1155 , A61B17/2909 , A61B17/295 , A61B90/92 , A61B2017/00004 , A61B2017/003 , A61B2017/00314 , A61B2017/00323 , A61B2017/00327 , A61B2017/00526 , A61B2017/0053 , A61B2017/00818 , A61B2017/00862 , A61B2017/00884 , A61B2017/00893 , A61B2017/0409 , A61B2017/0641 , A61B2017/0688 , A61B2017/07214 , A61B2017/07221 , A61B2017/07228 , A61B2017/07235 , A61B2017/07242 , A61B2017/0725 , A61B2017/07257 , A61B2017/07264 , A61B2017/07271 , A61B2017/07278 , A61B2017/2902 , A61B2017/2908 , A61B2017/291 , A61B2017/2919 , A61B2017/292 , A61B2017/2923 , A61B2017/2927 , A61B2017/2931 , A61B2017/2933 , A61B2017/2936 , A61B2017/2944 , A61B2017/2946 , A61B2017/320052 , A61B2090/037 , A61B2090/0811
摘要： A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened.
摘要翻译：紧固件盒可以包括支撑部分，相对于支撑部分定位的组织厚度补偿器，以及定位在支撑部分内的多个紧固件和/或可用于紧固组织的组织厚度补偿器。在使用中，紧固件盒可以定位在手术紧固装置的第一钳口中，其中第二钳口或砧座可以定位成与第一钳口相对。为了部署紧固件，订书钉展开构件通过紧固件盒推进，以将紧固件移向砧座。当紧固件被部署时，紧固件可以将组织厚度补偿器的至少一部分与至少一部分被紧固的组织一起捕获在其中。

39. 发明授权

US08814025B2 Fibrin pad matrix with suspended heat activated beads of adhesive 有权
标题翻译：纤维蛋白垫基质与悬浮热活化的粘合剂珠
公开(公告)号：US08814025B2
公开(公告)日：2014-08-26
申请号：US13233633
申请日：2011-09-15
申请人： Matthew C. Miller , Yi-Lan Wang , Israel Nur , Aron O. Zingman
发明人： Matthew C. Miller , Yi-Lan Wang , Israel Nur , Aron O. Zingman
IPC分类号： A61B17/068 , A61B17/00 , A61B17/072 , A61B17/29
CPC分类号： A61B17/07207 , A61B17/00491 , A61B17/07292 , A61B2017/005 , A61B2017/2929
摘要： A surgical instrument includes a handle portion, a shaft housing a firing bar, an end effector comprising an anvil, a lower jaw, and a stapling and severing assembly responsive to a longitudinal closing motion produced by the handle portion and the shaft. The lower jaw is configured to receive a cartridge when in an open position. The cartridge includes a housing, a plurality of staples disposed in the housing, and a deck disposed over the plurality of staples. The deck defines apertures, with each aperture being substantially disposed over each staple. The cartridge further receives a matrix including glue beads suspended in the matrix. The staples are driven through the matrix to secure the matrix to tissue. The glue beads are activated when the matrix is secured to the tissue, such that the activated adhesive further secures the staple line in the tissue.
摘要翻译：手术器械包括手柄部分，容纳击球杆的轴，包括砧座的末端执行器，下颚和响应于由手柄部分和轴产生的纵向关闭运动的装订和切断组件。下颚构造成在处于打开位置时接收盒。盒包括壳体，设置在壳体中的多个钉，以及设置在多个钉上的甲板。甲板限定孔，每个孔基本上设置在每个钉上。墨盒进一步接收包括悬浮在基质中的胶珠的基质。订书钉被驱动通过矩阵将矩阵固定在组织上。当基质被固定到组织上时，胶珠被活化，使得活化的粘合剂进一步固定组织中的缝合线。

40. 发明授权

US08640921B2 Device, system and method for dispensing a fixed dose of fluid 有权
标题翻译：用于分配固定剂量流体的装置，系统和方法
公开(公告)号：US08640921B2
公开(公告)日：2014-02-04
申请号：US13209650
申请日：2011-08-15
申请人： Moti Meron , Aner Tsuk , Roee Atlas , Israel Nur
发明人： Moti Meron , Aner Tsuk , Roee Atlas , Israel Nur
IPC分类号： B67D7/70
CPC分类号： A61B17/00491 , A61B2017/00495 , A61M5/19 , A61M5/204 , A61M5/31586 , A61M35/003
摘要： The invention relates to a device for dispensing a fixed dose of fluid, the device comprising at least one barrel; at least one plunger at least partially enclosed within the barrel; a motion conversion mechanism for transferring actuated pressure force applied outside the barrel into movement of the at least one plunger in a dispensing direction, wherein the motion conversion mechanism comprises at least one rotating gear; and a releasing mechanism for disconnecting the plunger from the motion conversion mechanism, wherein at a released position the at least one plunger can move in a direction opposite to the dispensing direction, independent of a rotational movement of the at least one gear, and wherein the movement of the plunger in the opposite direction to the dispensing enables loading the fluid into the barrel.
摘要翻译：本发明涉及一种用于分配固定剂量的流体的装置，该装置包括至少一个桶; 至少一个柱塞至少部分地封闭在所述筒体内; 运动转换机构，用于将施加到所述筒外部的致动压力传递到所述至少一个柱塞在分配方向上的运动，其中所述运动转换机构包括至少一个旋转齿轮; 以及用于将活塞与运动转换机构分离的释放机构，其中在释放位置，所述至少一个柱塞可以在与所述分配方向相反的方向上移动，而与所述至少一个齿轮的旋转运动无关，并且其中柱塞在与分配相反的方向上的运动使得能够将流体装载到筒中。

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