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31. 发明申请

US20100120672A1 CYCLIC PEPTIDE COMPOUNDS 有权
标题翻译：环肽类化合物
公开(公告)号：US20100120672A1
公开(公告)日：2010-05-13
申请号：US12598404
申请日：2008-04-25
申请人： Toshio Yamanaka , Hidenori Ohki , Junya Ishida , Ayako Toda , Yu Harayama , Takuya Makino , Shigeki Kunikawa , Hiroaki Mizuno , Hiroaki Ohtake
发明人： Toshio Yamanaka , Hidenori Ohki , Junya Ishida , Ayako Toda , Yu Harayama , Takuya Makino , Shigeki Kunikawa , Hiroaki Mizuno , Hiroaki Ohtake
IPC分类号： A61K38/12 , C07K7/64 , A61P31/12
CPC分类号： C07K7/645 , A61K38/00
摘要： The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, a process for preparation thereof, a pharmaceutical composition comprising the same, and a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
摘要翻译：本发明涉及一种基于对丙型肝炎病毒复制子的RNA复制的抑制活性的抗丙型肝炎病毒活性的新的环肽化合物或其盐，其制备方法，包含其的药物组合物，以及在人或动物中预防和/或治疗丙型肝炎的方法。

32. 发明申请

US20050261177A1 Compound 审中-公开
标题翻译：复合
公开(公告)号：US20050261177A1
公开(公告)日：2005-11-24
申请号：US10469233
申请日：2002-03-07
申请人： Ayako Toda , Hiroaki Mizuno , Takahiro Matsuya , Hiroshi Matsuda , Kenji Murano , David Barrett , Takashi Ogino , Hitomi Ogino , Keiji Matsuda
发明人： Ayako Toda , Hiroaki Mizuno , Takahiro Matsuya , Hiroshi Matsuda , Kenji Murano , David Barrett , Takashi Ogino , Hitomi Ogino , Keiji Matsuda
IPC分类号： A61K38/00 , A61P31/00 , A61P31/10 , C07K1/113 , C07K7/50 , C07K7/56
CPC分类号： C07K7/56 , A61K38/00
摘要： This invention relates to new polypeptide compound represented by the following general formula (I): wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on β-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
摘要翻译：本发明涉及由以下通式（I）表示的新的多肽化合物：其中R 1，R 2，R 3，R 3， SUP> 4，R 5和R 6如说明书中所定义或其具有抗微生物活性（特别是抗真菌活性）的抑制活性 β-1,3-葡聚糖合酶，其制备方法，涉及含有该组合物的药物组合物，以及用于预防和/或治疗感染性疾病的方法，包括卡氏肺囊虫感染（例如肺孢子虫卡氏肺炎）人类或动物。

33. 发明申请

US20050014685A1 New compound 审中-公开
标题翻译：新化合物
公开(公告)号：US20050014685A1
公开(公告)日：2005-01-20
申请号：US10873305
申请日：2004-06-23
申请人： Hiroaki Mizuno , Hiroshi Matsuda , Takahiro Matsuya , David Barrett
发明人： Hiroaki Mizuno , Hiroshi Matsuda , Takahiro Matsuya , David Barrett
IPC分类号： A61K38/00 , C07K7/56 , C07K7/64 , A61K38/12
CPC分类号： C07K7/56 , A61K38/00
摘要： This invention relates to new lipopeptide compound represented by the following general formula (I): Wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on β-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
摘要翻译：本发明涉及由以下通式（I）表示的新的脂肽化合物：其中R 1，R 2，R 3，R 4，R 5和R 6如上所定义在具有抗微生物活性（特别是抗真菌活性）的描述中，其对β-1,3-葡聚糖合酶的抑制活性，其制备方法，含有该活性的药物组合物，以及预防性方法和/或治疗性处理感染性疾病，包括人或动物的卡氏肺囊虫感染（例如肺孢子虫肺炎）。

34. 发明授权

US06278508B1 Reflection type liquid crystal display device 失效
标题翻译：反射型液晶显示装置
公开(公告)号：US06278508B1
公开(公告)日：2001-08-21
申请号：US09351531
申请日：1999-07-12
申请人： Tetsu Ogawa , Shingo Fujita , Hiroaki Mizuno , Yoshio Iwai
发明人： Tetsu Ogawa , Shingo Fujita , Hiroaki Mizuno , Yoshio Iwai
IPC分类号： G02F11335
CPC分类号： G02F1/133553 , G02F1/1334 , G02F1/133502 , G02F1/133504 , G02F1/133514 , G02F2001/13756
摘要： A reflector electrode is provided with hills and valleys thereon, and the reflector electrode is formed on an inside face of a transparent substrate having a transparent electrode and an opposite substrate. Light-scattering-liquid-crystal is provided with forward-scattering component and back-scattering component, so that scattering of reflected light from the reflector electrode is increased when the light-scattering-liquid-crystal is transparent. As a result, contrast is less dependent on a viewing angle, and a brighter quality display with higher color purity can be obtained.
摘要翻译：反射器电极在其上设置有山丘和谷，并且反射器电极形成在具有透明电极和相对基板的透明基板的内表面上。光散射液晶具有前向散射分量和反向散射分量，使得当光散射液晶透明时，来自反射器电极的反射光的散射增加。结果，对比度不太依赖于视角，并且可以获得具有更高色纯度的更亮的质量显示。

35. 发明授权

US06232290B1 Cyclic hexapeptides with antimicrobial activity 失效
标题翻译：具有抗菌活性的环状六肽
公开(公告)号：US06232290B1
公开(公告)日：2001-05-15
申请号：US09446101
申请日：1999-12-22
申请人： Hidenori Ohki , Kenji Murano , Takashi Tojo , Nobuyuki Shiraishi , Takahiro Matsuya , Hiroshi Matsuda , Hiroaki Mizuno , David Barrett , Keiji Matsuda , Kohji Kawabata
发明人： Hidenori Ohki , Kenji Murano , Takashi Tojo , Nobuyuki Shiraishi , Takahiro Matsuya , Hiroshi Matsuda , Hiroaki Mizuno , David Barrett , Keiji Matsuda , Kohji Kawabata
IPC分类号： A61K3812
CPC分类号： C07K7/56 , A61K38/00
摘要： This invention relates to new polypeptide compounds represented by general formula (I), wherein R1, R2, R3 and R4 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on &bgr;-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
摘要翻译：本发明涉及由通式（I）表示的新的多肽化合物，其中R1，R2，R3和R4如说明书中所定义或其具有抗微生物活性（特别是抗真菌活性）的盐，对β-1的抑制活性 3-葡聚糖合酶，其制备方法，涉及含有该组合物的药物组合物，以及用于预防和/或治疗感染性疾病的方法，包括卡介菌肺炎卡介菌感染（例如肺孢子虫卡氏肺炎）在人或动物。

36. 发明授权

US6055033A Color liquid crystal display device using polymer and polarization films 有权
标题翻译：彩色液晶显示装置采用聚合物和偏振膜
公开(公告)号：US6055033A
公开(公告)日：2000-04-25
申请号：US304248
申请日：1999-05-03
申请人： Hisanori Yamaguchi , Hiroaki Mizuno , Shingo Fujita , Tetsu Ogawa
发明人： Hisanori Yamaguchi , Hiroaki Mizuno , Shingo Fujita , Tetsu Ogawa
IPC分类号： G02F1/133 , G02F1/1335 , G02F1/13363 , G02F1/139
CPC分类号： G02F1/13363 , G02F1/1397 , G02F2203/34 , G02F2413/02 , G02F2413/07 , G02F2413/08
摘要： A color liquid crystal display device comprises a liquid crystal cell and a polymer film. The liquid crystal cell comprises a liquid crystal layer positioned between a pair of transparent substrates, on whose innersides transparent electrodes are provided. The polymer film is positioned at one side of the liquid crystal cell. The liquid crystal layer and the polymer film are sandwiched by a pair of polarization films. A twist angle of the liquid crystal layer is set to be a predetermined value. The product of birefringence of the nematic liquid crystal, .DELTA.n.sub.LC, and a thickness of liquid crystal layer, d.sub.LC, .DELTA.n.sub.LC .multidot.d.sub.LC is set to be a predetermined value. The birefringence difference .DELTA.(R)=R.sub.Film -.DELTA.n.sub.LC .multidot.d.sub.LC, which is defined by using the .DELTA.n.sub.LC .multidot.d.sub.LC and retardation of the polymer film, R.sub.Film, is set to be a value between 0.0 .mu.m and 0.1 .mu.m. The present color liquid crystal device can express a black and white display in achromatic color having bright white and with high contrast, and a red display with high color purity.
摘要翻译：彩色液晶显示装置包括液晶单元和聚合物膜。液晶单元包括位于一对透明基板之间的液晶层，其上设置有透明电极。聚合物膜位于液晶单元的一侧。液晶层和聚合物膜被一对偏光膜夹在中间。将液晶层的扭转角设定为规定值。向列型液晶的双折射产物，DELTA nLC和液晶层dLC，DELTA nLCxdLC的厚度被设定为预定值。通过使用DELTA nLCxdLC和聚合物膜的延迟RFilm定义的双折射差DELTA（R）= RFilm-DELTA nLCxdLC被设置为在0.0μm和0.1μm之间的值。本发明的彩色液晶显示装置可以表现出具有明亮的白色和高对比度的无彩色的黑白显示，以及高纯度的红色显示。

37. 发明申请

US20130032966A1 METHOD OF MANUFACTURING MOLDED ARTICLE INCLUDING COMPONENT INSERT-MOLDED IN MOLDING MATERIAL MIXED WITH SOLID POWDER 有权
标题翻译：制造模制品的方法，包括与固体粉末混合的模塑材料中嵌入成分的组分
公开(公告)号：US20130032966A1
公开(公告)日：2013-02-07
申请号：US13566567
申请日：2012-08-03
申请人： Bahman Hossini Soltani , Hiroaki Mizuno , Motohiro Ishibashi , Sadamu Shiotsuki
发明人： Bahman Hossini Soltani , Hiroaki Mizuno , Motohiro Ishibashi , Sadamu Shiotsuki
IPC分类号： D04H1/60
CPC分类号： B29C39/10 , B01F3/14 , B01F7/30 , B01F7/32 , B01F11/0054 , B01F11/0082 , B01F11/0088 , B29C39/006 , B29C39/24 , B29K2023/06 , B29K2105/16 , B29K2301/10 , B29K2995/0008 , H01F41/0246
摘要： The method of manufacturing a molded article including a component insert-molded in a molding material mixed with solid powder includes an injecting step of injecting the molding material and the solid powder into a molding die, an agitating step of agitating the molding material and the solid powder within the molding die to disperse the solid powder in the molding material, and an embedding step of pressing and embedding the component into an agitated mixture of the molding material and the solid powder.
摘要翻译：制造包含嵌入成型在与固体粉末混合的成型材料中的部件的成型制品的方法包括将成型材料和固体粉末注入成型模具中的注入步骤，搅拌成型材料和固体的搅拌步骤将成型材料中的固体粉末分散在成型模具内，以及嵌入步骤，将成分加压成型成型材料和固体粉末的混合物。

38. 发明申请

US20060108700A1 Semiconductor device, method and apparatus for fabricating the same 有权
标题翻译：半导体器件，其制造方法和装置
公开(公告)号：US20060108700A1
公开(公告)日：2006-05-25
申请号：US11273415
申请日：2005-11-14
申请人： Shusaku Nakazawa , Tsutomu Onoue , Hiroaki Mizuno , Hidehisa Nasu
发明人： Shusaku Nakazawa , Tsutomu Onoue , Hiroaki Mizuno , Hidehisa Nasu
IPC分类号： H01L23/28
CPC分类号： H01L24/33 , H01L21/565 , H01L23/4334 , H01L24/32 , H01L24/45 , H01L24/48 , H01L24/49 , H01L24/73 , H01L25/072 , H01L2224/32245 , H01L2224/33 , H01L2224/45124 , H01L2224/45144 , H01L2224/48091 , H01L2224/48247 , H01L2224/48472 , H01L2224/49171 , H01L2224/73215 , H01L2224/73265 , H01L2924/00014 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/01019 , H01L2924/01029 , H01L2924/01033 , H01L2924/0105 , H01L2924/01079 , H01L2924/01082 , H01L2924/1301 , H01L2924/1305 , H01L2924/13055 , H01L2924/181 , H01L2924/1815 , H01L2924/00 , H01L2924/00012 , H01L2224/45015 , H01L2924/207
摘要： A semiconductor device has at least one semiconductor element, at least one radiator plate thermally connected with said semiconductor element, and a molded resin covering and sealing said semiconductor device and said radiator, wherein an outer main surface of the radiator plate and at least a part of the side surface adjoining the outer main surface are exposed from the molded resin.
摘要翻译：半导体器件具有至少一个半导体元件，与所述半导体元件热连接的至少一个散热板，以及覆盖并密封所述半导体器件和所述散热器的模制树脂，其中散热板的外主表面和至少一部分与外侧主表面相邻的侧面露出。

39. 发明授权

US06884774B2 Cyclic hexapeptide derivatives 失效
标题翻译：环六肽衍生物
公开(公告)号：US06884774B2
公开(公告)日：2005-04-26
申请号：US10030161
申请日：2001-02-20
申请人： Ayako Toda , Takahiro Matsuya , Hiroaki Mizuno , Hiroshi Matsuda , Kenji Murano , David Barrett , Takashi Ogino , Keiji Matsuda
发明人： Ayako Toda , Takahiro Matsuya , Hiroaki Mizuno , Hiroshi Matsuda , Kenji Murano , David Barrett , Takashi Ogino , Keiji Matsuda
IPC分类号： A61K38/00 , A01N43/90 , A61J1/03 , A61K38/12 , A61P31/00 , A61P31/10 , C07K1/113 , C07K7/54 , C07K7/56 , C07K5/00
CPC分类号： C07K7/56 , A61K38/00
摘要： This invention relates to new polypeptide compound represented by the general formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on β-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystic carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
摘要翻译：本发明涉及由通式（I）表示的新的多肽化合物，其中R 1，R 2，R 3，R 3， 4，R 5和R 6如描述中所定义，或其盐具有抗微生物活性（特别是抗真菌活性），对β的抑制活性 -1,3-葡聚糖合酶，其制备方法，涉及含有该组合物的药物组合物，以及用于预防和/或治疗感染性疾病的方法，包括人类卡氏肺囊虫感染（例如肺孢子虫卡氏肺炎）或动物。

40. 发明授权

US06522378B1 Liquid crystal display and manufacture therefore 有权
标题翻译：因此液晶显示和制造
公开(公告)号：US06522378B1
公开(公告)日：2003-02-18
申请号：US09647014
申请日：2000-11-27
申请人： Hiroaki Mizuno , Masaki Nishinaka , Shingo Fujita , Tetsu Ogawa
发明人： Hiroaki Mizuno , Masaki Nishinaka , Shingo Fujita , Tetsu Ogawa
IPC分类号： G02F11343
CPC分类号： G02F1/13452 , G02F1/1345 , G02F1/136204 , H05K1/117 , H05K3/242
摘要： An electrode width of intermediate connection wiring which connects terminal electrode and common electrode is made narrower than an electrode width of terminal electrode at forming an electrode pattern on one of substrates configuring a liquid crystal display device. This enables the prevention of detrimental effect of cutting and polishing the periphery of a liquid crystal cell onto the terminal electrode. A laser irradiation process required for removing the common electrode is eliminated, and thus manufacturing cost may be reduced.
摘要翻译：连接端子电极和公共电极的中间连接配线的电极宽度比构成液晶显示装置的基板的一个上形成电极图案时的端子电极的电极宽度窄。这样可以防止将液晶单元的周边切割和抛光到端电极上的不利影响。消除了除去公共电极所需的激光照射工艺，因此可以降低制造成本。

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