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31. 发明申请

US20070185124A1 Cancer treatment with topoisomerase-ii inhibitor, a bis-dioxypiperazine and radiation 有权
标题翻译：用拓扑异构酶-II抑制剂，双二氧嘧啶和辐射进行癌症治疗
公开(公告)号：US20070185124A1
公开(公告)日：2007-08-09
申请号：US10591847
申请日：2005-03-02
申请人： Kenneth Hofland , Maxwell Sehested , Paul Kristjansen , Annenette Thougaard , Peter Jensen
发明人： Kenneth Hofland , Maxwell Sehested , Paul Kristjansen , Annenette Thougaard , Peter Jensen
IPC分类号： A61K31/497 , A61K31/357
CPC分类号： A61K31/496 , A61K31/7048 , A61K41/00 , A61K2300/00
摘要： The present invention relates to a method of treatment of a tumour cell which comprises administering to a subject in need of treatment an effective amount of a topoisomerase-II poison, e.g. etoposide, in combination with a bis-dioxypiperazine, e.g. dexrazoxane wherein said subject is further treated with radiation.
摘要翻译：本发明涉及一种治疗肿瘤细胞的方法，其包括向需要治疗的受试者施用有效量的拓扑异构酶II毒物，例如，依托泊苷，与双 - 二氧代哌嗪，其中所述受试者进一步用辐射治疗。

32. 发明申请

US20060144780A1 Process for removing perchlorate ions from water streams 有权
标题翻译：从水流中除去高氯酸根离子的方法
公开(公告)号：US20060144780A1
公开(公告)日：2006-07-06
申请号：US11219335
申请日：2005-09-01
申请人： Peter Jensen , Bryan Zinn , John Zitlau
发明人： Peter Jensen , Bryan Zinn , John Zitlau
IPC分类号： B01D35/28
CPC分类号： C02F1/42 , B01J41/04 , B01J47/00 , B01J2220/606 , C02F2001/422
摘要： Methods and systems for removing perchlorate from water are disclosed. They involve: Methods and systems for removing perchlorate from water are disclosed which involve the use of a plurality of vessels containing an ion exchange resin having affinity for perchlorate ions, and in which perchlorate-contaminated water is passed over the resin in some but not all of the plurality of vessels operating in parallel to one another thereby removing perchlorate ion from the water stream and generating reduced perchlorate content product water streams and in which a subset of the plurality of vessels is removed from service, their resin is removed and replaced and they are returned to service.
摘要翻译：公开了从水中除去高氯酸盐的方法和系统。它们涉及：从水中除去高氯酸盐的方法和系统，其涉及使用含有对高氯酸根离子具有亲和力的离子交换树脂的多个容器，其中高氯酸盐污染的水在一些但不是全部的多个容器彼此平行地操作，从而从水流中除去高氯酸根离子并产生降低的高氯酸盐含量的产物水流，并且其中多个容器的一部分被去除使用，它们的树脂被去除和替换，并且它们返回服务。

33. 发明申请

US20060094078A1 Method of improving the production of biomass or a desired product from a cell 失效
标题翻译：从细胞中提高生物质或所需产物的生产的方法
公开(公告)号：US20060094078A1
公开(公告)日：2006-05-04
申请号：US11075398
申请日：2005-03-07
申请人： Peter Jensen , Jacky Snoep , Hans Westerhoff
发明人： Peter Jensen , Jacky Snoep , Hans Westerhoff
IPC分类号： C12P21/06 , C12N15/74 , C12N1/18 , C12N1/21
CPC分类号： C12N1/16 , C12N1/20 , C12N9/14 , C12P1/00
摘要： The production of biomass or a desired product from a cell can be improved by inducing conversion of ATP to ADP without primary effects on other cellular metabolites or functions which is achieved by expressing an uncoupled ATPase activity in said cell and incubating the cell with a suitable substrate to produce said biomass or product. This is conveniently done by expressing in said cell the soluble part (F1) of the membrane bound (F0F1 type) H+-ATPase or a portion of F1 exhibiting ATPase activity. The organism from which the F1 ATPase or portions thereof is derived, or in which the F1 ATPase or portions thereof is expressed, may be selected from prokaryotes and eukaryotes. In particular, the DNA encoding F1 or a portion thereof may be derived from bacteria and eukaryotic microorganisms such as yeast, other fungi and cell lines of higher organisms and be selected from the group consisting of the gene encoding the F1 subunit beta or a portion thereof and various combinations of said gene or portion with the genes encoding the other F1 subunits or portions thereof. The method can be used i.a. for optimizing the formation of biomass or a desired product by a cell by expressing different levels of uncoupled ATPase activity in the cell, incubating the cell on a suitable substrate, measuring the conversion rate of substrate into biomass or the desired product at each level of ATPase expression, and choosing a level of ATPase expression at which the conversion rate is optimized.
摘要翻译：通过诱导ATP向ADP的转化而不会对其它细胞代谢物或功能产生主要影响，可以改善生物量或细胞所需产物的产生，这通过在所述细胞中表达非偶联的ATP酶活性并将细胞与合适的底物以产生所述生物质或产品。方便地通过在所述细胞中表达所结合的膜的可溶部分（F 1 O 1 H 1 H 2） -ATPase或显示出ATP酶活性的F 1 N 1的一部分。衍生自其中的F 1 N 1 ATP酶或其部分或其中表达F 1 N ATP酶或其部分的生物可以选自原核生物和真核生物。特别地，编码F 1 N或其一部分的DNA可以衍生自细菌和真核微生物如酵母，其他真菌和高等生物的细胞系，并且可以选自编码 F亚基β或其部分以及所述基因或部分与编码其他F 1 N亚基或其部分的基因的各种组合。该方法可以使用i.a 通过在细胞中表达不同水平的解偶联的ATP酶活性来优化生物量或所需产物的形成，将细胞孵育在合适的底物上，测量底物转化成生物质或每种ATPase水平的所需产物的转化率表达，并选择转化率优化的ATPase表达水平。

34. 发明申请

US20050161404A1 High efficiency ion exchange system for removing contaminants from water 有权
标题翻译：用于从水中去除污染物的高效离子交换系统
公开(公告)号：US20050161404A1
公开(公告)日：2005-07-28
申请号：US11085961
申请日：2005-03-21
申请人： Peter Jensen , Gerald Guter , Dan Ziol
发明人： Peter Jensen , Gerald Guter , Dan Ziol
IPC分类号： B01J47/14 , B01J49/00 , C02F1/00 , C02F1/42 , C02F1/72 , C02F1/76
CPC分类号： C02F1/42 , B01J47/14 , B01J49/05 , B01J49/85 , C02F1/008 , C02F1/72 , C02F1/76 , C02F2101/10 , C02F2101/103 , C02F2101/12 , C02F2101/16 , C02F2101/163 , C02F2101/22 , C02F2209/005 , C02F2303/16 , Y10S210/902 , Y10S210/903 , Y10S210/912 , Y10S210/913
摘要： The disclosed invention is a fixed bed ion exchange water purification system. It employs a combination of electronically controlled process steps and specific systems configurations to duplicate the effects of moving resin beds from one operation position to another as is required in moving bed ion exchange water purification systems. The invention combines features of single fixed bed ion exchange systems with those of a moving bed system. The invention applies to the treatment of water having typical industrial and drinking water concentrations of various ions.
摘要翻译：所公开的发明是固定床离子交换水净化系统。它采用电子控制工艺步骤和特定系统配置的组合，以将移动树脂床从一个操作位置到另一个操作位置的影响，如移动床离子交换水净化系统所需。本发明结合了单一固定床离子交换系统与移动床系统的特征。本发明适用于具有各种离子典型工业和饮用水浓度的水的处理。

35. 发明授权

US06478363B2 Protective cover device for use with a snowmobile 失效
标题翻译：用于雪地车的防护罩装置
公开(公告)号：US06478363B2
公开(公告)日：2002-11-12
申请号：US09784562
申请日：2001-02-15
申请人： Peter Jensen
发明人： Peter Jensen
IPC分类号： B60J1100
CPC分类号： B62M27/02 , B62J19/00
摘要： A protective cover device is disclosed for use with a snowmobile having an engine compartment, windshield, handlebars, seat, track and skis. The protective cover is used for protecting the snowmobile from the elements during transportation thereof. The device includes a first portion for covering and protecting the engine compartment, windshield, handlebars and seat of the snowmobile. A second portion covers the track and skis. An arrangement is provided for removably sealing the first and second portions together such that when the first and second portions are sealed together, the first and second portions define therebetween an enclosure for the snowmobile. The arrangement is such that during transportation of the snowmobile, ingress of the elements such as H2O, snow, slush and road contaminants onto the snowmobile is inhibited. The protective cover device enables the snowmobile to be completely protected and insulated from the elements that would otherwise tend to damage, corrode and reduce the usefulness of the snowmobile in the absence of the cover device.
摘要翻译：公开了一种用于具有发动机舱，挡风玻璃，车把，座椅，轨道和滑雪板的雪地车的保护盖装置。保护罩用于在运输过程中保护雪地车辆免受元件的伤害。该装置包括用于覆盖和保护发动机舱，挡风玻璃，车把和雪地车的座椅的第一部分。第二部分覆盖轨道和滑雪板。提供了一种用于可拆卸地将第一和第二部分密封在一起的装置，使得当第一和第二部分被密封在一起时，第一和第二部分在其间限定了用于雪地车辆的外壳。这种布置使得在雪车的运输过程中，诸如H2O，雪，泥浆和道路污染物等元素的侵入被抑制在雪地车上。保护盖装置能够使雪地摩托车完全受到保护，并且与在没有盖装置的情况下会趋于损坏，腐蚀并降低雪地车的有用性的元件完全保护和绝缘。

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