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31. 发明申请

US20050065207A1 Method for the preparation of escitalopram 审中-公开
标题翻译：艾司西酞普兰的制备方法
公开(公告)号：US20050065207A1
公开(公告)日：2005-03-24
申请号：US10483824
申请日：2002-07-12
申请人： Michael Sommer , Ole Nielsen , Hans Petersen , Haleh Ahmadian , Henrik Pedersen , Peter Brosen , Fiona Geiser , James Lee , Geoffrey Cox , Olivier Dapremont , Christina Suteu , Sebastian Assenza , Shankar Hariharan , Usha Nair
发明人： Michael Sommer , Ole Nielsen , Hans Petersen , Haleh Ahmadian , Henrik Pedersen , Peter Brosen , Fiona Geiser , James Lee , Geoffrey Cox , Olivier Dapremont , Christina Suteu , Sebastian Assenza , Shankar Hariharan , Usha Nair
IPC分类号： A61K31/343 , A61P25/24 , C07B20060101 , C07C215/32 , C07C215/34 , C07D20060101 , C07D307/87
CPC分类号： C07C215/32 , C07D307/87
摘要： A novel method is provided for the manufacture of escitalopram. The method comprises chromatographic separation of the enantiomers of citalopram or an intermediate in the production of citalopram using a chiral stationary phase such as Chiralpak™ or Chiralcel™ OD. Novel chiral intermediates for the synthesis of Escitalopram made by said method are also provided.
摘要翻译：提供了一种制备依他普仑的新方法。该方法包括使用手性固定相（例如Chiralpak TM或Chiralcel TM OD）对西酞普兰对映异构体或西酞普兰生产中的中间体进行色谱分离。还提供了通过所述方法制备的用于合成依他普仑的新型手性中间体。

32. 发明申请

US20050053652A1 Pharmaceutical composition containing citalopram 审中-公开
标题翻译：含西酞普兰的药物组合物
公开(公告)号：US20050053652A1
公开(公告)日：2005-03-10
申请号：US10966725
申请日：2004-10-15
申请人： Ken Liljegren , Per Holm , Ole Nielsen , Sven Wagner
发明人： Ken Liljegren , Per Holm , Ole Nielsen , Sven Wagner
IPC分类号： A61K9/20 , A61K9/48 , A61K9/64 , A61K31/343 , C07D307/87 , A61K31/495
CPC分类号： C07D307/87 , A61K9/2054 , A61K9/4866 , A61K31/343
摘要： A solid unit dosage form comprising citalopram, which is prepared by direct compression of a mixture of citalopram base or a pharmaceutically acceptable salt thereof and pharmaceutically acceptable excipients, or by filling of said mixture in a hard gelatine capsule. Large crystals of a pharmaceutical acceptable salt of citalopram and method for the manufacture of said large crystals.
摘要翻译：包含西酞普兰的固体单位剂型，其通过直接压制西酞普兰碱或其药学上可接受的盐和药学上可接受的赋形剂的混合物或通过将所述混合物填充在硬明胶胶囊中来制备。西酞普兰药物可接受盐的大晶体和用于制造所述大晶体的方法。

33. 发明授权

US06849659B2 Pharmaceutical composition containing citalopram 有权
公开(公告)号：US06849659B2
公开(公告)日：2005-02-01
申请号：US09730380
申请日：2000-12-05
申请人： Ken Liljegren , Per Holm , Ole Nielsen , Sven Wagner
发明人： Ken Liljegren , Per Holm , Ole Nielsen , Sven Wagner
摘要： A solid unit dosage form comprising citalopram, which is prepared by direct compression of a mixture of citalopram base or a pharmaceutically acceptable salt thereof and pharmaceutically acceptable excipients, or by filling of said mixture in a hard gelatine capsule. Large crystals of a pharmaceutical acceptable salt of citalopram and method for the manufacture of said large crystals.

34. 发明授权

US06327981B1 Carriage body 失效
标题翻译：车身
公开(公告)号：US06327981B1
公开(公告)日：2001-12-11
申请号：US09423886
申请日：1999-11-19
申请人： Kjeld Nørregaard , Claus Bratsbjerg , Jens Jørgen Graakjær Jensen , Ole Nielsen
发明人： Kjeld Nørregaard , Claus Bratsbjerg , Jens Jørgen Graakjær Jensen , Ole Nielsen
IPC分类号： B61D1700
CPC分类号： B61D17/18 , B61D17/043
摘要： A carriage body for a vehicle is described. It is possible to perform a displacement of a frame element (8) with respect to the outlook through windows (5) from each seat (14) in a train coach. Thus, the frame elements (8) are fastened to the cover plates (3, 4) of the coach above and below the window (5) via grooves (11) in which there are provided connecting means (13) sliding in the grooves (11). Hereby the frame elements (8) may be displaced longitudinally relative to the coach.
摘要翻译：描述车辆的车体。可以通过来自列车车厢中的每个座（14）的窗口（5）来执行框架元件（8）相对于前景的位移。因此，框架元件（8）经由槽（11）紧固到车窗上方和下方的教练座（3,4），其中设置有在凹槽中滑动的连接装置（13） 11）。因此，框架元件（8）可以相对于教练纵向移位。

35. 发明授权

US5237943A Manipulating and sewing two trouser portions having rim strips to a zipper and apparatus used therein 失效
标题翻译：操作和缝制带有拉链的RIM条带和使用的装置的两个TROUSER部分
公开(公告)号：US5237943A
公开(公告)日：1993-08-24
申请号：US785503
申请日：1991-10-30
申请人： Michael Klein , Benny Lapp , Ole Nielsen
发明人： Michael Klein , Benny Lapp , Ole Nielsen
IPC分类号： A44B19/00 , A41H37/06 , D05B35/06
CPC分类号： A41H37/06 , D05B35/064
摘要： In addition to a sewing machine, a sewing unit has a workpiece holder, which has two workpiece bearing plates displaceable relative to each other, a holding bar, a folding, bar, a thrower device, a cloth slider and a folding device. By these devices, first and second trouser parts having rim strips are faced and overlapped inside-out onto a zipper. The front inseam is sewn, then the rim strip of the second trouser part is folded over and a first zipper seam is sewn. The second trouser part is folded over right-side out and the j-seam is sewn. The rim strips of the first and second trouser parts can be folded before sewing, seam locks can be provided, and a lower covering strip can be provided to the zipper as well. Thus, all three seams can be sewn with a single sewing arrangement.
摘要翻译：除了缝纫机之外，缝纫单元具有工件保持器，其具有可相对于彼此移位的两个工件轴承板，保持杆，折叠杆，投掷器装置，布滑块和折叠装置。通过这些装置，具有边缘条的第一和第二长裤部分面向内并重叠到拉链上。将前部内缝缝合，然后将第二裤部的边缘条折叠起来，缝制第一拉链缝。第二个裤子部分从右侧折叠出来，缝合j缝。第一和第二裤子部件的边缘条可以在缝合之前折叠，可以提供缝缝，并且也可以向拉链提供下覆盖带。因此，所有三个接缝都可以缝合一个单一的缝合布置。

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